Modeling of Enterococcus faecalis D-alanine: D-alanine ligase: Structure-based study of the active site in the wild-type enzyme and in glycopeptide-dependent mutants

Journal of Molecular Microbiology and Biotechnology

Volumn 2, Issue 3, 2000, Pages 321-330

  Prévost, Martine ^a   Van Belle, Daniel ^a   Tulkens, Paul M ^b   Courvalin, Patrice ^c   Van Bambeke, Françoise ^b  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; DEXTRO ALANINE DEXTRO ALANINE LIGASE;

ARTICLE; CATALYSIS; DELETION MUTANT; DRUG DESIGN; DRUG TARGETING; ENTEROCOCCUS FAECALIS; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROGEN BOND; MOLECULAR MODEL; NONHUMAN; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

ADENOSINE DIPHOSPHATE; AMINO ACID SEQUENCE; BINDING SITES; CATALYTIC DOMAIN; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; GLYCOPEPTIDES; MAGNESIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE SYNTHASES; PHOSPHATES; PHOSPHINES; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI;

EID: 0342264622     PISSN: 14641801     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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