D-alanine:D-alanine ligase: Phosphonate and phosphinate intermediates with wild type and the Y216F mutant

Biochemistry

Volumn 36, Issue 9, 1997, Pages 2531-2538

  Fan, Chang ^a   Park, Il Seon ^b   Walsh, Christopher T ^b   Knox, James R ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRO ALANINE DEXTRO ALANINE LIGASE; PHOSPHONIC ACID DERIVATIVE; VANCOMYCIN;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; ENZYME BINDING; ENZYME INHIBITION; ENZYME STRUCTURE; ESCHERICHIA COLI; INHIBITION KINETICS; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HYDROXYBUTYRATES; MOLECULAR SEQUENCE DATA; PEPTIDE SYNTHASES; PHOSPHINIC ACIDS; PHOSPHONIC ACIDS;

ESCHERICHIA COLI;

EID: 0031020216     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962431t     Document Type: Article

References (33)

1. Arthur, M., & Courvalin, P. (1993) Antimicrob. Agents Chemother. 37, 1563-1571.
2. Artymiuk, P. J., Poirrette, A. R., Rice, D. W., & Willett, P. (1996) Nat. Struct. Biol. 3, 128-132.
3. Brunger, A. T. (1990) X-PLOR Manual, Version 2.1, Yale University, New Haven, CT.
4. Brunger, A. T. (1992) Nature 355, 472-475.
5. Carson, M. (1987) J. Mol. Graphics 5, 103-106.
6. Chakravarty, P. K., Greenlee, W. J., Parsons, W. H., Patchett, A. A., Combs, P., Roth, A., Busch, R. D., & Mellin, T. N. (1989) J. Med. Chem. 32, 1886-1890.
7. Duncan, K., & Walsh, C. T. (1988) Biochemistry 27, 3709-3714.
8. Duncan, K., Faraci, W. S., Matteson, D. S., & Walsh, C. T. (1989) Biochemistry 28, 3541-3549.
9. Dutka-Malen, S., Molinas, C., Arthur, M., & Courvalin, P. (1990) Mol. Gen. Genet. 224, 364-372.
10. Ellsworth, B. A., Tom, N. J., & Bartlett, P. A. (1996) Chem. Biol. 3, 37-44.
11. Fan, C., Moews, P. C., Walsh, C. T., & Knox, J. R. (1994) Science 266, 439-443.
12. Fan, C., Moews, P. C., Shi, Y., Walsh, C. T., & Knox, J. R. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 1172-1176.
13. Hibi, T., Nishioka, T., Kato, H., Tanizawa, K., Fukui, T., Katsube, T., & Uda, J. (1996) Nat. Struct. Biol. 3, 16-18.
14. Hiratake, J., Kato, H., & Oda, J. (1994) J. Am. Chem. Soc. 116, 12059-12060.
15. Howard, A. J., Gilliland, G. L., Finzel, B. C., Poulos, T. L., Ohlendorf, D. H., & Salemme, F. R. (1987) J. Appl. Crystallogr. 20, 383-387.
16. Jones, T. A. (1985) Methods Enzymol. 115, 157-170.
17. Knox, J. R. (1995) Antimicrob. Agents Chemother. 39, 2593-2601.
18. Konnert, J. H., & Hendrickson, W. A. (1980) Acta Crystallogr., Sect. A 36, 344-349.
19. Kraulis, P. (1991) J. Appl. Crystallogr. 24, 946-950.
20. Leclerq, R., Derlot, E., Duval, J., & Courvalin, P. (1988) N. Engl. J. Med. 319, 157-161.
21. Luzzati, V. (1952) Acta Crystallogr. 5, 802-810.
22. McDermott, A. E., Creuzet, F., Griffin, R. G., Zawadzke, L. E., Ye, Q.-Z., & Walsh, C. T. (1990) Biochemistry 29, 5767-5775.
23. Mullins, L. S., Zawadzke, L. E., Walsh, C. T., & Raushel, F. M. (1990) J. Biol. Chem. 265, 8993-8998.
24. Murzin, A. G. (1996) Curr. Opin. Struct. Biol. 6, 386-394.
25. Neuhaus, F. C., & Hammes, W. P. (1981) Pharmacol. Ther. 14, 265-319.
26. Neuhaus, F. C., & Lynch, J. L. (1964) Biochemistry 3, 477-480.
27. Park, I.-S., Lin, C.-H., & Walsh, C. T. (1996) Biochemistry 35, 10464-10471.
28. Parsons, W. H., Patchett, A. A., Bull, H. G., Schoen, W. R., Taub, D., Davidson, J., Combs, P., Springer, J. P., Gadebusch, H., Weissberger, B., Valiant, M. E., Mellin, T. N., & Busch, R. D. (1988) J. Med. Chem. 31, 1772-1778.
29. Sack, J. S. (1988) J. Mol. Graphics 6, 224-225.
30. Shi, Y., & Walsh, C. T. (1995) Biochemistry 34, 2768-2776.
31. Spratt, B. G. (1994) Science 264, 388-393.
32. Walsh, C. T. (1993) Science 261, 308-309.
33. Zawadzke, L. E., Bugg, T. D. H., & Walsh, C. T. (1991) Biochemistry 30, 1673-1682.