Active-site mutants of the VanC2 D-alanyl-D-serine ligase, characteristic of one vancomycin-resistant bacterial phenotype, revert towards wild-type D-alanyl-D-alanine ligases

Chemistry and Biology

Volumn 5, Issue 4, 1998, Pages 197-207

  Healy, Vicki L ^a   Park, Il Seon ^a   Walsh, Christopher T ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Active site mutants; D alanyl D alanine ligase; D alanyl D serine ligase; Reversed specificity; Vancomycin resistance

Indexed keywords

BACTERIA (MICROORGANISMS); ENTEROCOCCUS; ENTEROCOCCUS CASSELIFLAVUS; ESCHERICHIA COLI;

EID: 0032054820     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(98)90633-0     Document Type: Article

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