Specificity and catalysis of uracil DNA glycosylase. A molecular dynamics study of reactant and product complexes with DNA

Biochemistry

Volumn 38, Issue 29, 1999, Pages 9209-9220

  Luo, Ning ^a   Mehler, Ernest ^a   Osman, Roman ^a,b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; ASPARTIC ACID; CYTOSINE; DEOXYRIBOSE; DOUBLE STRANDED DNA; HISTIDINE; URACIL; URACIL DNA GLYCOSYLTRANSFERASE;

ARTICLE; CATALYSIS; CHEMICAL BINDING; ENZYME SPECIFICITY; HYDROGEN BOND; HYDROLYSIS; MOLECULAR DYNAMICS; PRIORITY JOURNAL; REACTION ANALYSIS; SIMULATION;

ASPARTIC ACID; BINDING SITES; CATALYSIS; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DNA; DNA GLYCOSYLASES; HISTIDINE; HYDROLYSIS; MACROMOLECULAR SUBSTANCES; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTATION; N-GLYCOSYL HYDROLASES; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; THERMODYNAMICS; URACIL-DNA GLYCOSIDASE;

EID: 0033587492     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990262h     Document Type: Article

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