Structure-based design, synthesis, and X-ray crystallography of a high- affinity antagonist of the Grb2-SH2 domain containing an asparagine mimetic

Journal of Medicinal Chemistry

Volumn 42, Issue 13, 1999, Pages 2358-2363

  Furet, Pascal ^a   García Echeverría, Carlos ^a   Gay, Brigitte ^a   Schoepfer, Joseph ^a   Zeller, Martin ^b   Rahuel, Joseph ^b  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO PHOSPHOTYROSINE 1 AMINOCYCLOHEXANE CARBOXYLIC ACID ASPARAGINE AMIDE; ADAPTOR PROTEIN; ASPARAGINE DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; PHOSPHOPEPTIDE; PROTEIN TYROSINE KINASE; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; PEPTIDE SYNTHESIS; PROTEIN DOMAIN; X RAY CRYSTALLOGRAPHY;

EID: 0344731437     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm991013u     Document Type: Article

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