-
1
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG, et al: Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235:177-182, 1987
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
-
2
-
-
0034469081
-
Tyrosine kinase signalling in breast cancer: Insulin-like growth factors and their receptors in breast cancer
-
Zhang X, Yee D: Tyrosine kinase signalling in breast cancer: insulin-like growth factors and their receptors in breast cancer. Breast Cancer Res 2:170-175, 2000
-
(2000)
Breast Cancer Res
, vol.2
, pp. 170-175
-
-
Zhang, X.1
Yee, D.2
-
3
-
-
0005096726
-
Tissue concentrations of somatomedin C: Further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action
-
D'Ercole AJ, Stiles AD, Underwood LE: Tissue concentrations of somatomedin C: Further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci U S A 81:935-939, 1984
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 935-939
-
-
D'Ercole, A.J.1
Stiles, A.D.2
Underwood, L.E.3
-
4
-
-
0024550730
-
Analysis of insulin-like growth factor I gene expression in malignancy: Evidence for a paracrine role in human breast cancer
-
Yee D, Paik S, Lebovic GS, et al: Analysis of insulin-like growth factor I gene expression in malignancy: Evidence for a paracrine role in human breast cancer. Mol Endocrinol 3:509-517, 1989
-
(1989)
Mol Endocrinol
, vol.3
, pp. 509-517
-
-
Yee, D.1
Paik, S.2
Lebovic, G.S.3
-
5
-
-
0029849442
-
IGF-II mRNA and protein are expressed in the stroma of invasive breast cancers: An in situ hybridization and immunohistochemistry study
-
Giani C, Cullen KJ, Campani D, et al: IGF-II mRNA and protein are expressed in the stroma of invasive breast cancers: an in situ hybridization and immunohistochemistry study. Breast Cancer Res Treat 41:43-50, 1996
-
(1996)
Breast Cancer Res Treat
, vol.41
, pp. 43-50
-
-
Giani, C.1
Cullen, K.J.2
Campani, D.3
-
6
-
-
0026746298
-
Expression of IGF-I and IGF-II mRNA in breast tissue
-
Paik S: Expression of IGF-I and IGF-II mRNA in breast tissue. Breast Cancer Res Treat 22:31-38, 1992
-
(1992)
Breast Cancer Res Treat
, vol.22
, pp. 31-38
-
-
Paik, S.1
-
7
-
-
0032230339
-
p42/p44 mitogen-activated protein kinases activation is required for the insulin-like growth factor-I/insulin induced proliferation, but inhibits differentiation, in rat fetal brown adipocytes
-
Porras A, Alvarez AM, Valladares A, et al: p42/p44 mitogen-activated protein kinases activation is required for the insulin-like growth factor-I/insulin induced proliferation, but inhibits differentiation, in rat fetal brown adipocytes. Mol Endocrinol 12:825-834, 1998
-
(1998)
Mol Endocrinol
, vol.12
, pp. 825-834
-
-
Porras, A.1
Alvarez, A.M.2
Valladares, A.3
-
8
-
-
0032589192
-
Role of AKT1 in 17beta-estradiol- and insulin-like growth factor I (IGF-I)-dependent proliferation and prevention of apoptosis in MCF-7 breast carcinoma cells
-
Ahmad S, Singh N, Glazer RI: Role of AKT1 in 17beta-estradiol- and insulin-like growth factor I (IGF-I)-dependent proliferation and prevention of apoptosis in MCF-7 breast carcinoma cells. Biochem Pharmacol 58:425-430, 1999
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 425-430
-
-
Ahmad, S.1
Singh, N.2
Glazer, R.I.3
-
9
-
-
0034465670
-
Insulin-like growth factor I activates c-jun N-terminal kinase in MCF-7 breast cancer cells
-
Monno S, Newman MV, Cook M, et al: Insulin-like growth factor I activates c-jun N-terminal kinase in MCF-7 breast cancer cells. Endocrinology 141:544-550, 2000
-
(2000)
Endocrinology
, vol.141
, pp. 544-550
-
-
Monno, S.1
Newman, M.V.2
Cook, M.3
-
10
-
-
0036682286
-
Insulin-like growth factor binding protein-1 (IGFBP-1) inhibits breast cancer cell motility
-
Zhang X, Yee D: Insulin-like growth factor binding protein-1 (IGFBP-1) inhibits breast cancer cell motility. Cancer Res 62:4369-4375, 2002
-
(2002)
Cancer Res
, vol.62
, pp. 4369-4375
-
-
Zhang, X.1
Yee, D.2
-
11
-
-
0034677588
-
Cooperative interaction between mutant p53 and des(1-3)IGF-I accelerates mammary tumorigenesis
-
Hadsell DL, Murphy KL, Bonnette SG, et al: Cooperative interaction between mutant p53 and des(1-3)IGF-I accelerates mammary tumorigenesis. Oncogene 19:889-898, 2000
-
(2000)
Oncogene
, vol.19
, pp. 889-898
-
-
Hadsell, D.L.1
Murphy, K.L.2
Bonnette, S.G.3
-
12
-
-
4243742260
-
Serum IGF-I levels as a risk marker in mammary tumors
-
abstr
-
Yakar S, Green J, LeRoith D: Serum IGF-I levels as a risk marker in mammary tumors. Proc Endocr Soc 201:P1-242, 2001 (abstr)
-
(2001)
Proc Endocr Soc
, vol.201
-
-
Yakar, S.1
Green, J.2
LeRoith, D.3
-
13
-
-
0029129747
-
Insulin-like growth-factor-binding protein 3 is decreased in early-stage operable pre-menopausal breast cancer
-
Bruning PF, Van Doorn J, Bonfrer JM, et al: Insulin-like growth-factor-binding protein 3 is decreased in early- stage operable pre-menopausal breast cancer. Int J Cancer 62:266-270, 1995
-
(1995)
Int J Cancer
, vol.62
, pp. 266-270
-
-
Bruning, P.F.1
Van Doorn, J.2
Bonfrer, J.M.3
-
14
-
-
0034571504
-
Serum insulin-like growth factor-I and breast cancer
-
Toniolo P, Bruning PF, Akhmedkhanov A, et al: Serum insulin-like growth factor-I and breast cancer. Int J Cancer 88:828-832, 2000
-
(2000)
Int J Cancer
, vol.88
, pp. 828-832
-
-
Toniolo, P.1
Bruning, P.F.2
Akhmedkhanov, A.3
-
15
-
-
0025611672
-
Effect of tamoxifen on serum insulin-like growth factor I levels in stage I breast cancer patients
-
Pollak M, Costantino J, Polychronakos C, et al: Effect of tamoxifen on serum insulin-like growth factor I levels in stage I breast cancer patients. J Natl Cancer Inst 82:1693-1697, 1990
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1693-1697
-
-
Pollak, M.1
Costantino, J.2
Polychronakos, C.3
-
16
-
-
0026806159
-
The effect of endocrine therapy with medroxyprogesterone acetate, 4-hydroxyandrostenedione or tamoxifen on plasma concentrations of insulin-like growth factor (IGF)-I, IGF-II and IGFBP-1 in women with advanced breast cancer
-
Reed MJ, Christodoulides A, Koistinen R, et al: The effect of endocrine therapy with medroxyprogesterone acetate, 4- hydroxyandrostenedione or tamoxifen on plasma concentrations of insulin-like growth factor (IGF)-I, IGF-II and IGFBP-1 in women with advanced breast cancer. Int J Cancer 52:208-212, 1992
-
(1992)
Int J Cancer
, vol.52
, pp. 208-212
-
-
Reed, M.J.1
Christodoulides, A.2
Koistinen, R.3
-
17
-
-
0028157211
-
The role of the IGF-I receptor in the growth and transformation of mammalian cells
-
Baserga R, Sell C, Porcu P, et al: The role of the IGF-I receptor in the growth and transformation of mammalian cells. Cell Prolif 27:63-71, 1994
-
(1994)
Cell Prolif
, vol.27
, pp. 63-71
-
-
Baserga, R.1
Sell, C.2
Porcu, P.3
-
18
-
-
0025166350
-
Insulin-like growth factor receptor expression and function in human breast cancer
-
Cullen KJ, Yee D, Sly WS, et al: Insulin-like growth factor receptor expression and function in human breast cancer. Cancer Res 50:48-53, 1990
-
(1990)
Cancer Res
, vol.50
, pp. 48-53
-
-
Cullen, K.J.1
Yee, D.2
Sly, W.S.3
-
19
-
-
0026710682
-
Insulin receptor expression and function in human breast cancer cell lines
-
Milazzo G, Giorgino F, Damante G, et al: Insulin receptor expression and function in human breast cancer cell lines. Cancer Res 52:3924-3930, 1992
-
(1992)
Cancer Res
, vol.52
, pp. 3924-3930
-
-
Milazzo, G.1
Giorgino, F.2
Damante, G.3
-
20
-
-
0029920101
-
Insulin-like growth factor-I (IGF-I) receptors in breast cancer
-
Pezzino V, Papa V, Milazzo G, et al: Insulin-like growth factor-I (IGF-I) receptors in breast cancer. Ann N Y Acad Sci 784:189-201, 1996
-
(1996)
Ann N Y Acad Sci
, vol.784
, pp. 189-201
-
-
Pezzino, V.1
Papa, V.2
Milazzo, G.3
-
21
-
-
0032521210
-
Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer
-
Resnik JL, Reichart DB, Huey K, et al: Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer. Cancer Res 58:1159-1164, 1998
-
(1998)
Cancer Res
, vol.58
, pp. 1159-1164
-
-
Resnik, J.L.1
Reichart, D.B.2
Huey, K.3
-
22
-
-
16944364325
-
Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation
-
Turner BC, Haffty BG, Narayanan L, et al: Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation. Cancer Res 57:3079-3083, 1997
-
(1997)
Cancer Res
, vol.57
, pp. 3079-3083
-
-
Turner, B.C.1
Haffty, B.G.2
Narayanan, L.3
-
23
-
-
0026605211
-
Sporadic amplification of the insulin-like growth factor 1 receptor gene in human breast tumors
-
Berns EM, Klijn JG, van Staveren IL, et al: Sporadic amplification of the insulin-like growth factor 1 receptor gene in human breast tumors. Cancer Res 52:1036-1039, 1992
-
(1992)
Cancer Res
, vol.52
, pp. 1036-1039
-
-
Berns, E.M.1
Klijn, J.G.2
Van Staveren, I.L.3
-
24
-
-
0031051830
-
Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: Correlation with clinical parameters and disease-free survival
-
Rocha RL, Hilsenbeck SG, Jackson JG, et al: Insulin-like growth factor binding protein-3 and insulin receptor substrate-1 in breast cancer: Correlation with clinical parameters and disease-free survival. Clin Cancer Res 3:103-109, 1997
-
(1997)
Clin Cancer Res
, vol.3
, pp. 103-109
-
-
Rocha, R.L.1
Hilsenbeck, S.G.2
Jackson, J.G.3
-
25
-
-
0033305004
-
Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo
-
Lee AV, Jackson JG, Gooch JL, et al: Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo. Mol Endocrinol 13:787-796, 1999
-
(1999)
Mol Endocrinol
, vol.13
, pp. 787-796
-
-
Lee, A.V.1
Jackson, J.G.2
Gooch, J.L.3
-
26
-
-
0029998031
-
A carboxy-terminal truncated insulin receptor substrate-1 dominant negative protein reverses the human hepatocellular carcinoma malignant phenotype
-
Tanaka S, Wands JR: A carboxy-terminal truncated insulin receptor substrate-1 dominant negative protein reverses the human hepatocellular carcinoma malignant phenotype. J Clin Invest 98:2100-2108, 1996
-
(1996)
J Clin Invest
, vol.98
, pp. 2100-2108
-
-
Tanaka, S.1
Wands, J.R.2
-
27
-
-
0031031824
-
Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells
-
Lee AV, Weng CN, Jackson JG, et al: Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells. J Endocrinol 152:39-47, 1997
-
(1997)
J Endocrinol
, vol.152
, pp. 39-47
-
-
Lee, A.V.1
Weng, C.N.2
Jackson, J.G.3
-
28
-
-
0030000351
-
Intracellular transactivation of the insulin-like growth factor I receptor by an epidermal growth factor receptor
-
Burgaud JL, Baserga R: Intracellular transactivation of the insulin-like growth factor I receptor by an epidermal growth factor receptor. Exp Cell Res 223:412-419, 1996
-
(1996)
Exp Cell Res
, vol.223
, pp. 412-419
-
-
Burgaud, J.L.1
Baserga, R.2
-
29
-
-
0035915421
-
Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)
-
Lu Y, Zi X, Zhao Y, et al: Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). J Natl Cancer Inst 93:1852-1857, 2001
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1852-1857
-
-
Lu, Y.1
Zi, X.2
Zhao, Y.3
-
30
-
-
0033559620
-
A randomized trial of tamoxifen alone or combined with octreotide in the treatment of women with metastatic breast carcinoma
-
Ingle JN, Suman VJ, Kardinal CG, et al: A randomized trial of tamoxifen alone or combined with octreotide in the treatment of women with metastatic breast carcinoma. Cancer 85:1284-1292, 1999
-
(1999)
Cancer
, vol.85
, pp. 1284-1292
-
-
Ingle, J.N.1
Suman, V.J.2
Kardinal, C.G.3
-
32
-
-
0035381062
-
Cancer and the potential place for growth hormone receptor antagonist therapy
-
Friend KE: Cancer and the potential place for growth hormone receptor antagonist therapy. Growth Horm IGF Res A:S121-123, 2001 (suppl 11)
-
(2001)
Growth Horm IGF Res
, vol.A
, Issue.SUPPL. 11
-
-
Friend, K.E.1
-
33
-
-
0034811213
-
Antagonists of GHRH decrease production of GH and IGF-I in MXT mouse mammary cancers and inhibit tumor growth
-
Szepeshazi K, Schally AV, Armatis P, et al: Antagonists of GHRH decrease production of GH and IGF-I in MXT mouse mammary cancers and inhibit tumor growth. Endocrinology 142:4371-4378, 2001
-
(2001)
Endocrinology
, vol.142
, pp. 4371-4378
-
-
Szepeshazi, K.1
Schally, A.V.2
Armatis, P.3
-
34
-
-
0024408247
-
Growth inhibition of human breast cancer cells in vitro with an antibody against the type I somatomedin receptor
-
Arteaga CL, Osborne CK: Growth inhibition of human breast cancer cells in vitro with an antibody against the type I somatomedin receptor. Cancer Res 49:6237-6241, 1989
-
(1989)
Cancer Res
, vol.49
, pp. 6237-6241
-
-
Arteaga, C.L.1
Osborne, C.K.2
-
35
-
-
0024460381
-
Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice
-
Arteaga CL, Kitten LJ, Coronado EB, et al: Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice. J Clin Invest 84:1418-1423, 1989
-
(1989)
J Clin Invest
, vol.84
, pp. 1418-1423
-
-
Arteaga, C.L.1
Kitten, L.J.2
Coronado, E.B.3
-
36
-
-
0033929947
-
Single-chain antibodies against human insulin-like growth factor I receptor: Expression, purification, and effect on tumor growth
-
Li SL, Liang SJ, Guo N, et al: Single-chain antibodies against human insulin-like growth factor I receptor: Expression, purification, and effect on tumor growth. Cancer Immunol Immunother 49:243-252, 2000
-
(2000)
Cancer Immunol Immunother
, vol.49
, pp. 243-252
-
-
Li, S.L.1
Liang, S.J.2
Guo, N.3
-
37
-
-
0027454916
-
Effect of endocrine therapy on growth of T61 human breast cancer xenografts is directly correlated to a specific down-regulation of insulin-like growth factor II (IGF-II)
-
Brunner N, Yee D, Kern FG, et al: Effect of endocrine therapy on growth of T61 human breast cancer xenografts is directly correlated to a specific down-regulation of insulin-like growth factor II (IGF-II). Eur J Cancer 4:562-569, 1993
-
(1993)
Eur J Cancer
, vol.4
, pp. 562-569
-
-
Brunner, N.1
Yee, D.2
Kern, F.G.3
-
38
-
-
20244364227
-
Inhibition of insulin-like growth factor I receptor increases the antitumor activity of doxorubicin and vincristine against Ewing's sarcoma cells
-
Benini S, Manara MC, Baldini N, et al: Inhibition of insulin-like growth factor I receptor increases the antitumor activity of doxorubicin and vincristine against Ewing's sarcoma cells. Clin Cancer Res 7:1790-1797, 2001
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1790-1797
-
-
Benini, S.1
Manara, M.C.2
Baldini, N.3
-
39
-
-
0033768157
-
Insulin-like growth factor I receptor antagonism augmenrs response to chemoradiation therapy in colon cancer cells
-
Perer ES, Madan AK, Shurin A, et al: Insulin-like growth factor I receptor antagonism augmenrs response to chemoradiation therapy in colon cancer cells. J Surg Res 94: 1-5, 2000
-
(2000)
J Surg Res
, vol.94
, pp. 1-5
-
-
Perer, E.S.1
Madan, A.K.2
Shurin, A.3
-
40
-
-
0025374861
-
Discrete alterations of the insulin-like growth factor I molecule which alter its affinity for insulin-like growth factor-binding proteins result in changes in bioactivity
-
Clemmons DR, Cascieri MA, Camacho-Hubner C, et al: Discrete alterations of the insulin- like growth factor I molecule which alter its affinity for insulin-like growth factor-binding proteins result in changes in bioactivity. J Biol Chem 265:12210-12216, 1990
-
(1990)
J Biol Chem
, vol.265
, pp. 12210-12216
-
-
Clemmons, D.R.1
Cascieri, M.A.2
Camacho-Hubner, C.3
-
41
-
-
0026483202
-
Inhibition of cellular proliferation by peptide analogues of insulin-like growth factor 1
-
Pietrzkowski Z, Wernicke D, Porcu P, et al: Inhibition of cellular proliferation by peptide analogues of insulin-like growth factor 1. Cancer Res 52:6447-6451, 1992
-
(1992)
Cancer Res
, vol.52
, pp. 6447-6451
-
-
Pietrzkowski, Z.1
Wernicke, D.2
Porcu, P.3
-
42
-
-
0027407639
-
Inhibition of growth of prostatic cancer cell lines by peptide analogues of insulin-like growth factor 1
-
Pietrzkowski Z, Mulholland G, Gomella L, et al: Inhibition of growth of prostatic cancer cell lines by peptide analogues of insulin-like growth factor 1. Cancer Res 53:1102-1106, 1993
-
(1993)
Cancer Res
, vol.53
, pp. 1102-1106
-
-
Pietrzkowski, Z.1
Mulholland, G.2
Gomella, L.3
-
43
-
-
0027385551
-
Recombinant insulin-like growth factor binding protein-1 inhibits IGF-I, serum, and estrogen-dependent growth of MCF-7 human breast cancer cells
-
Figueroa JA, Sharma J, Jackson JG, et al: Recombinant insulin-like growth factor binding protein-1 inhibits IGF-I, serum, and estrogen-dependent growth of MCF-7 human breast cancer cells. J Cell Physiol 157:229-236, 1993
-
(1993)
J Cell Physiol
, vol.157
, pp. 229-236
-
-
Figueroa, J.A.1
Sharma, J.2
Jackson, J.G.3
-
44
-
-
0028169507
-
Insulin-like growth factor binding protein 1 expression inhibits insulin-like growth factor I action in MCF-7 breast cancer cells
-
Yee D, Jackson JG, Kozelsky TW, et al: Insulin-like growth factor binding protein 1 expression inhibits insulin-like growth factor I action in MCF-7 breast cancer cells. Cell Growth Differ 5:73-77, 1994
-
(1994)
Cell Growth Differ
, vol.5
, pp. 73-77
-
-
Yee, D.1
Jackson, J.G.2
Kozelsky, T.W.3
-
45
-
-
0030872966
-
Polyethylene glycol conjugated insulin-like growth factor binding protein-1 (IGFBP-1) inhibits growth of breast cancer in athymic mice
-
Van den Berg CL, Cox GN, Stroh CA, et al: Polyethylene glycol conjugated insulin-like growth factor binding protein-1 (IGFBP-1) inhibits growth of breast cancer in athymic mice. Eur J Cancer 33:1108-1113, 1997
-
(1997)
Eur J Cancer
, vol.33
, pp. 1108-1113
-
-
Van Den Berg, C.L.1
Cox, G.N.2
Stroh, C.A.3
-
46
-
-
0031589538
-
Insulin-like growth factor binding protein-3 induces apoptosis in MCF7 breast cancer cells
-
Nickerson T, Huynh H, Pollak M: Insulin-like growth factor binding protein-3 induces apoptosis in MCF7 breast cancer cells. Biochem Biophys Res Commun 237:690-693, 1997
-
(1997)
Biochem Biophys Res Commun
, vol.237
, pp. 690-693
-
-
Nickerson, T.1
Huynh, H.2
Pollak, M.3
-
47
-
-
0027199617
-
Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition
-
Oh Y, Muller HL, Lamson G, et al: Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition. J Biol Chem 268:14964-14971, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 14964-14971
-
-
Oh, Y.1
Muller, H.L.2
Lamson, G.3
-
48
-
-
0030972216
-
Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta 1 on programmed cell death through a p53- and IGF-independent mechanism
-
Rajah R, Valentinis B, Cohen P: Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta 1 on programmed cell death through a p53- and IGF-independent mechanism. J Biol Chem 272:12181-12188, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 12181-12188
-
-
Rajah, R.1
Valentinis, B.2
Cohen, P.3
-
49
-
-
0037205495
-
Insulin-like growth factor-binding protein-3 activates a phosphotyrosine phosphatase. Effects on the insulin-like growth factor signaling pathway
-
Ricort J-M, Binoux M: Insulin-like growth factor-binding protein-3 activates a phosphotyrosine phosphatase. Effects on the insulin-like growth factor signaling pathway. J Biol Chem 277:19448-19454, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 19448-19454
-
-
Ricort, J.-M.1
Binoux, M.2
-
50
-
-
0031960861
-
Effects of silymarin in alcoholic patients with cirrhosis of the liver: Results of a controlled, double-blind, randomized and multicenter trial
-
Pares A, Planas R, Torres M, et al: Effects of silymarin in alcoholic patients with cirrhosis of the liver: Results of a controlled, double-blind, randomized and multicenter trial. J Hepatol 28:615-621, 1998
-
(1998)
J Hepatol
, vol.28
, pp. 615-621
-
-
Pares, A.1
Planas, R.2
Torres, M.3
-
51
-
-
0032008339
-
Milk thistle (Silybum marianum) for the therapy of liver disease
-
Flora K, Hahn M, Rosen H, et al: Milk thistle (Silybum marianum) for the therapy of liver disease. Am J Gastroenterol 93:139-143, 1998
-
(1998)
Am J Gastroenterol
, vol.93
, pp. 139-143
-
-
Flora, K.1
Hahn, M.2
Rosen, H.3
-
52
-
-
0034667455
-
Silibinin up-regulates insulin-like growth factor-binding protein 3 expression and inhibits proliferation of androgen-independent prostate cancer cells
-
Zi X, Zhang J, Agarwal R, et al: Silibinin up-regulates insulin-like growth factor-binding protein 3 expression and inhibits proliferation of androgen-independent prostate cancer cells. Cancer Res 60:5617-5620, 2000
-
(2000)
Cancer Res
, vol.60
, pp. 5617-5620
-
-
Zi, X.1
Zhang, J.2
Agarwal, R.3
-
53
-
-
0036214015
-
Treatment of murine breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor decreases the level of plasminogen activator transcripts, inhibits cell growth in vitro, and reduces tumorigenesis in vivo
-
Chernicky CL, Tan H, Yi L, et al: Treatment of murine breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor decreases the level of plasminogen activator transcripts, inhibits cell growth in vitro, and reduces tumorigenesis in vivo. Mol Pathol 55:102-109, 2002
-
(2002)
Mol Pathol
, vol.55
, pp. 102-109
-
-
Chernicky, C.L.1
Tan, H.2
Yi, L.3
-
54
-
-
0029125689
-
Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid
-
Neuenschwander S, Roberts CT Jr, LeRoith D: Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid. Endocrinol 136:4298-4303, 1995
-
(1995)
Endocrinol
, vol.136
, pp. 4298-4303
-
-
Neuenschwander, S.1
Roberts Jr., C.T.2
LeRoith, D.3
-
55
-
-
0035811559
-
Down-regulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase
-
Macaulay VM, Salisbury AJ, Bohula EA, et al: Down-regulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase. Oncogene 20: 4029-4040, 2001
-
(2001)
Oncogene
, vol.20
, pp. 4029-4040
-
-
Macaulay, V.M.1
Salisbury, A.J.2
Bohula, E.A.3
-
56
-
-
0035871490
-
Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomas
-
Andrews DW, Resnicoff M, Flanders AE, et al: Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomas. J Clin Oncol 19: 2189-2200, 2001
-
(2001)
J Clin Oncol
, vol.19
, pp. 2189-2200
-
-
Andrews, D.W.1
Resnicoff, M.2
Flanders, A.E.3
-
57
-
-
0028318393
-
Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site
-
Werner H, Rauscher FJ III, Sukhetme VP, et al: Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site. J Biol Chem 269:12577-12582, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 12577-12582
-
-
Werner, H.1
Rauscher III, F.J.2
Sukhetme, V.P.3
-
58
-
-
0029757120
-
Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene
-
Werner H, Karnieli E, Rauscher FJ III, et al: Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene. PNAS 93:8318-8323, 1996
-
(1996)
PNAS
, vol.93
, pp. 8318-8323
-
-
Werner, H.1
Karnieli, E.2
Rauscher III, F.J.3
-
59
-
-
0030054870
-
Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth
-
Carlberg M, Dricu A, Blegen H, et al: Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth. J Biol Chem 271:17453-17462, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 17453-17462
-
-
Carlberg, M.1
Dricu, A.2
Blegen, H.3
-
60
-
-
0030909657
-
Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins
-
Parrizas M, Gazit A, Levitzki A, et al: Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins. Endocrinol 138:1427-1433, 1997
-
(1997)
Endocrinol
, vol.138
, pp. 1427-1433
-
-
Parrizas, M.1
Gazit, A.2
Levitzki, A.3
-
61
-
-
0034719133
-
Substrate competitive inhibitors of IGF-1 receptor kinase
-
Blum G, Gazit A, Levitzki A: Substrate competitive inhibitors of IGF-1 receptor kinase. Biochemistry 39:15705-15712, 2000
-
(2000)
Biochemistry
, vol.39
, pp. 15705-15712
-
-
Blum, G.1
Gazit, A.2
Levitzki, A.3
-
62
-
-
0031785253
-
Inhibition of tumor growth by a dominant negative mutant of the insulin-like growth factor I receptor with a bystander effect
-
Reiss K, D'Ambrosio C, Tu X, et al: Inhibition of tumor growth by a dominant negative mutant of the insulin-like growth factor I receptor with a bystander effect. Clin Cancer Res 4:2647-2655, 1998
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2647-2655
-
-
Reiss, K.1
D'Ambrosio, C.2
Tu, X.3
-
63
-
-
0029791877
-
A soluble insulin-like growth factor I receptor that induces apoptosis of tumor cells in vivo and inhibits tumorigenesis
-
D'Ambrosio C, Ferber A, Resnicoff M, et al: A soluble insulin-like growth factor I receptor that induces apoptosis of tumor cells in vivo and inhibits tumorigenesis. Cancer Res 56:4013-4020, 1996
-
(1996)
Cancer Res
, vol.56
, pp. 4013-4020
-
-
D'Ambrosio, C.1
Ferber, A.2
Resnicoff, M.3
-
64
-
-
0032146711
-
A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer
-
Dunn SE, Ehrlich M, Sharp NJ, et al: A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer. Cancer Res 58:3353-3361, 1998
-
(1998)
Cancer Res
, vol.58
, pp. 3353-3361
-
-
Dunn, S.E.1
Ehrlich, M.2
Sharp, N.J.3
-
65
-
-
0037102303
-
Proinflammatory cytokines block growth of breast cancer cells by impairing signals from a growth factor receptor
-
Shen WH, Zhou JH, Broussard SR, et al: Proinflammatory cytokines block growth of breast cancer cells by impairing signals from a growth factor receptor. Cancer Res 62:4746-4756, 2002
-
(2002)
Cancer Res
, vol.62
, pp. 4746-4756
-
-
Shen, W.H.1
Zhou, J.H.2
Broussard, S.R.3
|