Role of AKT1 in 17β-estradiol- and insulin-like growth factor I (IGF-I)-dependent proliferation and prevention of apoptosis in MCF-7 breast carcinoma cells

Biochemical Pharmacology

Volumn 58, Issue 3, 1999, Pages 425-430

  Ahmad, Shakeel ^a,b   Singh, Nadia ^a,b   Glazer, Robert I ^a,b  

^a GEORGETOWN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

AKT1; Apoptosis; Estradiol; IGF I; MCF 7 cells

Indexed keywords

DNA FRAGMENT; ENZYME INHIBITOR; ESTRADIOL; FULVESTRANT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SERINE THREONINE KINASE; RECOMBINANT SOMATOMEDIN C; WORTMANNIN; AKT1 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN KINASE B; SOMATOMEDIN C;

APOPTOSIS; ARTICLE; BREAST CARCINOMA; BREAST EPITHELIUM; CELL LINE; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG ANTAGONISM; DRUG POTENTIATION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ONCOGENE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; BIOSYNTHESIS; BREAST TUMOR; CELL CULTURE; CELL DIVISION; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; PATHOLOGY; PHYSIOLOGY;

APOPTOSIS; BREAST NEOPLASMS; CELL DIVISION; ENZYME ACTIVATION; ESTRADIOL; HUMANS; INSULIN-LIKE GROWTH FACTOR I; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0032589192     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00125-2     Document Type: Article

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