메뉴 건너뛰기




Volumn 12, Issue 6, 1998, Pages 825-834

P42/p44 mitogen-activated protein kinases activation is required for the insulin-like growth factor-i/insulin induced proliferation, but inhibits differentiation, in rat fetal brown adipocytes

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; FATTY ACID SYNTHASE; INSULIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; SOMATOMEDIN C; UNCOUPLING PROTEIN 1;

EID: 0032230339     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.12.6.0122     Document Type: Article
Times cited : (66)

References (52)
  • 10
    • 0027165150 scopus 로고
    • The Mitogen-activated protein kinase signal transduction pathway
    • (1993) J Biol Chem , vol.268 , pp. 14553-14556
    • Davis, R.J.1
  • 11
    • 0028897113 scopus 로고
    • Transcriptional regulation by extracellular signals: Mechanisms and specificity
    • (1995) Cell , vol.80 , pp. 199-211
    • Hill, C.S.1    Treisman, R.2
  • 12
    • 0005261734 scopus 로고
    • Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1502-1506
    • Ray, L.B.1    Sturgill, T.W.2
  • 16
    • 0028223704 scopus 로고
    • Dissociation between activation of Raf-1 kinase and the 42-kDa Mitogen-activated protein kinase/90-kDa S6 kinase (MAPK/RSK) cascade in the insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells
    • (1994) J Biol Chem , vol.269 , pp. 12741-12748
    • Porras, A.1    Muszynski, K.2    Rapp, U.R.3    Santos, E.4
  • 20
    • 0028907351 scopus 로고
    • Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DNA synthesis
    • (1995) EMBO J , vol.14 , pp. 674-684
    • Sale, E.M.1    Atkinson, P.G.P.2    Sale, G.J.3
  • 24
    • 0025089836 scopus 로고
    • Development of the uncoupling protein in the rat brown adipose tissue during the perinatal period: Its relationship with the mitochondrial GDP-binding and GDP-sensitive ion permeabilities and respiration
    • (1990) Eur J Biochem , vol.187 , pp. 671-675
    • Porras, A.1    Penas, M.2    Fernandez, M.3    Benito, M.4
  • 33
    • 0026575818 scopus 로고
    • Ras proteins are essential and selective for the action of insulin-like growth factor 1 late in the G1 phase of the cell cycle in BALB/c murine fibroblasts
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3889-3893
    • Lu, K.1    Campisi, J.2
  • 36
    • 0029917838 scopus 로고    scopus 로고
    • The insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells: Cissociation between Raf-1 kinase and the MAPK/RSK cascade
    • (1996) Int J Obesity , vol.20
    • Porras, A.1    Santos, E.2
  • 50
    • 0027339540 scopus 로고
    • P21ras-induced meiotic maturation of Xenopus oocytes in the absence of protein synthesis: MPF activation is preceded by activation of MAP and S6 kinases
    • (1993) Oncogene , vol.8 , pp. 466-477
    • Nebreda, A.R.1    Porras, A.2    Santos, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.