The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis

Oncogene

Volumn 22, Issue 42 REV. ISS. 4, 2003, Pages 6725-6738

  Mikula, Mario ^a   Gotzmann, Josef ^a   Fischer, Alexandra N M ^a   Wolschek, Markus F ^b   Thallinger, Christiane ^b   Schulte Hermann, Rolf ^a   Beug, Hartmut ^c   Mikulits, Wolfgang ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

c Fos; Cell death; Hepatocytes; Tumour suppressor

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL XL; PROTEIN C FOS; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; BCL2L1 PROTEIN, MOUSE; CCAAT ENHANCER BINDING PROTEIN; DDIT3 PROTEIN, MOUSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PROTEIN BCL 2; PROTEIN BCL X; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL DEATH; DEPOLARIZATION; GENE ACTIVATION; GENE EXPRESSION; HUMAN; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; NONHUMAN; ONCOGENE C FOS; ONCOGENE H RAS; ONCOGENE RAS; PHENOTYPE; PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; CELL DIVISION; CELL LINE; CELL SURVIVAL; CELL TRANSFORMATION; EPITHELIUM CELL; FLOW CYTOMETRY; GENETIC TRANSFECTION; LIVER TUMOR; METABOLISM; MOUSE; SIGNAL TRANSDUCTION; TIME; UPREGULATION;

ANIMALIA; MURINAE;

ANIMALS; APOPTOSIS; BCL-X PROTEIN; CARCINOMA, HEPATOCELLULAR; CCAAT-ENHANCER-BINDING PROTEINS; CELL DEATH; CELL DIVISION; CELL LINE; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL CELLS; FLOW CYTOMETRY; GENES, RAS; LIVER NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; PHENOTYPE; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-FOS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 0242521500     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206781     Document Type: Article

References (82)

1. Albrecht JH, Poon RY, Ahonen CL, Rieland BM, Deng C and Crary GS. (1998). Oncogene, 16, 2141-2150.
2. Amicone L, Spagnoli FM, Spath G, Giordano S, Tommasini C, Bernardini S, De Luca V, Della Rocca C, Weiss MC, Comoglio PM and Tripodi M. (1997). EMBO J., 16, 495-503.
3. Andersen H, Mahmood S, Tkach V, Cohn M, Kustikova O, Grigorian M, Berezin V, Bock E, Lukanidin E and Tulchinsky E. (2002). Oncogene, 21, 4843-4848.
4. Angel P and Karin M. (1991). Biochim. Biophys. Acta, 1072, 129-157.
5. Antonsson B, Conti F, Ciavatta A, Montessuit S, Lewis S, Martinou I, Bernasconi L, Bernard A, Mermod JJ, Mazzei G, Maundrell K, Gambale F, Sadoul R and Martinou JC. (1997). Science, 277, 370-372.
6. Barone MV, Crozat A, Tabaee A, Philipson L and Ron D. (1994). Genes Dev., 8, 453-464.
7. Bedossa P, Peltier E, Terris B, Franco D and Poynard T. (1995). Hepatology, 21, 760-766.
8. Behrens A, Sibilia M, David JP, Mohle-Steinlein U, Tronche F, Schutz G and Wagner EF. (2002). EMBO J., 21, 1782-1790.
9. Brusselbach S, Mohle-Steinlein U, Wang ZQ, Schreiber M, Lucibello FC, Muller R and Wagner EF. (1995). Oncogene, 10, 79-86.
10. Buendia MA. (2000). Semin. Cancer Biol., 10, 185-200.
11. Buttyan R, Zakeri Z, Lockshin R and Wolgemuth D. (1988). Mol. Endocrinol., 2, 650-657.
12. Carmichael J, DeGraff WG, Gazdar AF, Minna JD and Mitchell JB. (1987). Cancer Res., 47, 936-942.
13. Columbano A and Shinozuka H. (1996). FASEB J., 10, 1118-1128.
14. Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S and Gauthier JM. (1998). EMBO J., 17, 3091-3100.
15. Eferl R, Sibilia M, Hilberg F, Fuchsbichler A, Kufferath I, Guertl B, Zenz R, Wagner EF and Zatloukal K. (1999). J. Cell Biol., 145, 1049-1061.
16. Eger A, Stockinger A, Schaffhauser B, Beug H and Foisner R. (2000). J. Cell Biol., 148, 173-188.
17. Factor VM, Kao CY, Santoni-Rugiu E, Woitach JT, Jensen MR and Thorgeirsson SS. (1997). Cancer Res., 57, 2089-2095.
18. Fausto N. (2000). J. Hepatol., 32, 19-31.
19. Fialka I, Schwarz H, Reichmann E, Busslinger M and Beug H. (1996). J. Cell Biol., 132, 1115-1132.
20. Garcia EJ, Lawson D, Cotsonis G and Cohen C. (2002). Appl. Immunohistochem. Mol. Morphol., 10, 210-217.
21. Germain S, Howell M, Esslemont GM and Hill CS. (2000). Genes Dev., 14, 435-451.
22. Gotzmann J, Huber H, Wolschek M, Jansen B, Schulte-Hermann R, Beug H and Mikulits W. (2002). J. Cell Sci., 115, 1189-1202.
23. Grad JM, Zeng XR and Boise LH. (2000). Curr. Opin. Oncol., 12, 543-549.
24. Grasl-Kraupp B, Ruttkay-Nedecky B, Koudelka H, Bukowska K, Bursch W and Schulte-Hermann R. (1995). Hepatology, 21, 1465-1468.
25. Guyton KZ, Xu Q and Holbrook NJ. (1996). Biochem. J., 314, 547-554.
26. Hafezi F, Steinbach JP, Marti A, Munz K, Wang ZQ, Wagner EF, Aguzzi A and Reme CE. (1997). Nat. Med., 3, 346-349.
27. Herrera B, Alvarez AM, Sanchez A, Fernandez M, Roncero C, Benito M and Fabregat I. (2001a). FASEB J., 15, 741-751.
28. Herrera B, Fernandez M, Alvarez AM, Roncero C, Benito M, Gil J and Fabregat I. (2001b). Hepatology, 34, 548-556.
29. Hilberg F, Aguzzi A, Howells N and Wagner EF. (1993). Nature, 365, 179-181.
30. Holt JT, Gopal TV, Moulton AD and Nienhuis AW. (1986). Proc. Natl. Acad. Sci. USA, 83, 4794-4798.
31. Hu L, Hatano M, Ruther U and Tokuhisa T. (1996). J. Immunol., 157, 3804-3811.
32. Ito N, Kawata S, Tamura S, Takaishi K, Shirai Y, Kiso S, Yabuuchi I, Matsuda Y, Nishioka M and Tarui S. (1991). Cancer Res., 51, 4080-4083.
33. Ito Y, Sasaki Y, Horimoto M, Wada S, Tanaka Y, Kasahara A, Ueki T, Hirano T, Yamamoto H, Fujimoto J, Okamoto E, Hayashi N and Hori M. (1998). Hepatology, 27, 951-958.
34. Janda E, Lehmann K, Killisch I, Jechlinger M, Herzig M, Downward J, Beug H and Grunert S. (2002). J. Cell Biol., 156, 299-313.
35. Jochum W, Passegue E and Wagner EF. (2001). Oncogene, 20, 2401-2412.
36. Karin M. (1995). J. Biol. Chem., 270, 16483-16486.
37. Kieslinger M, Woldman I, Moriggl R, Hofmann J, Marine JC, Ihle JN, Beug H and Decker T. (2000). Genes Dev., 14, 232-244.
38. Kustikova O, Kramerov D, Grigorian M, Berezin V, Bock E, Lukanidin E and Tulchinsky E. (1998). Mol. Cell. Biol., 18, 7095-7105.
39. Lee M, Hyun DH, Marshall KA, Ellerby LM, Bredesen DE, Jenner P and Halliwell B. (2001). Free Radic. Biol. Med., 31, 1550-1559.
40. Marti A, Jehn B, Costello E, Keon N, Ke G, Martin F and Jaggi R. (1994). Oncogene, 9, 1213-1223.
41. Massague J. (2000). Nat. Rev. Mol. Cell. Biol., 1, 169-178.
42. Massague J, Blain SW and Lo RS. (2000). Cell, 103, 295-309.
43. Michalopoulos GK and DeFrances MC. (1997). Science, 276, 60-66.
44. Mikula M, Schreiber M, Husak Z, Rüth J, Wieser R, Zatloukal K, Beug H, Wagner EF and Baccarini M. (2001). EMBO J., 20, 1952-1962.
45. Mils V, Piette J, Barette C, Veyrune J, Tesniere A, Escot C, Guilhou JJ and Basset-Seguin N. (1997). Oncogene, 14, 1555-1561.
46. Nakai S, Masaki T, Shiratori Y, Ohgi T, Morishita A, Kurokohchi K, Watanabe S and Kuriyama S. (2002). Int. J. Oncol., 20, 769-775.
47. Nakopoulou L, Stefanaki K, Vourlakou C, Manolaki N, Gakiopoulou H and Michalopoulos G. (1999). Pathol. Res. Pract., 195, 19-24.
48. Oft M, Heider KH and Beug H. (1998). Curr. Biol., 8, 1243-1252.
49. Oft M, Peli J, Rudaz C, Schwarz H, Beug H and Reichmann E. (1996). Genes Dev., 10, 2462-2477.
50. Papadopoulos MC, Koumenis IL, Xu L and Giffard RG. (1998). Eur. J. Neurosci., 10, 1252-1260.
51. Pistoi S and Morello D. (1996). FASEB J., 10, 819-828.
52. Preston GA, Lyon TT, Yin Y, Lang JE, Solomon G, Annab L, Srinivasan DG, Alcorta DA and Barrett JC. (1996). Mol. Cell. Biol., 16, 211-218.
53. Qin LF and Ng IO. (2001). Hum. Pathol., 32, 778-784.
54. Rahmani M, Nadori F, Durand-Schneider AM, Lardeux B and Bernuau D. (1999). J. Hepatol., 30, 916-925.
55. Ravazoula P, Tsamandas AC, Kardamakis D, Gogos C, Karatza C, Thomopoulos K, Tepetes K, Kourelis T, Petsas T, Bonikos DS and Karavias D. (2002). Anticancer Res., 22, 1799-1805.
56. Reichmann E, Schwarz H, Deiner EM, Leitner I, Eilers M, Berger J, Busslinger M and Beug H. (1992). Cell, 71, 1103-1116.
57. Rodriguez-Viciana P, Warne PH, Khwaja A, Marte BM, Pappin D, Das P, Waterfield MD, Ridley A and Downward J. (1997). Cell, 89, 457-467.
58. Rossmanith W and Schulte-Hermann R. (2001). Microsc. Res. Technol., 52, 430-436.
59. Ruther U, Garber C, Komitowski D, Muller R and Wagner EF. (1987). Nature, 325, 412-416.
60. Ruther U, Komitowski D, Schubert FR and Wagner EF. (1989). Oncogene, 4, 861-865.
61. Saez E, Rutberg SE, Mueller E, Oppenheim H, Smoluk J, Yuspa SH and Spiegelman BM. (1995). Cell, 82, 721-732.
62. Schreiber M, Baumann B, Cotten M, Angel P and Wagner EF. (1995). EMBO J., 14, 5338-5349.
63. Sebolt-Leopold JS, Dudley DT, Herrera R, Van Becelaere K, Wiland A, Gowan RC, Tecle H, Barrett SD, Bridges A, Przybranowski S, Leopold WR and Saltiel AR. (1999). Nat. Med., 5, 810-816.
64. Sevilla L, Zaldumbide A, Pognonec P and Boulukos KE. (2001). Histol. Histopathol., 16, 595-601.
65. Shaulian E and Karin M. (2001). Oncogene, 20, 2390-2400.
66. Shaulian E and Karin M. (2002). Nat. Cell Biol., 4, E131-E136.
67. Smeal T, Binetruy B, Mercola DA, Birrer M and Karin M. (1991). Nature, 354, 494-496.
68. Smeyne RJ, Vendrell M, Hayward M, Baker SJ, Miao GG, Schilling K, Robertson LM, Curran T and Morgan JI. (1993). Nature, 363, 166-169.
69. Smith MJ and Prochownik EV. (1992). Blood, 79, 2107-2115.
70. Sok J, Wang XZ, Batchvarova N, Kuroda M, Harding H and Ron D. (1999). Mol. Cell. Biol., 19, 495-504.
71. Spagnoli FM, Amicone L, Tripodi M and Weiss MC. (1998). J. Cell Biol., 143, 1101-1112.
72. Steinhusen U, Weiske J, Badock V, Tauber R, Bommert K and Huber O. (2001). J. Biol. Chem., 276, 4972-4980.
73. Stockinger A, Eger A, Wolf J, Beug H and Foisner R. (2001). J. Cell Biol., 154, 1185-1196.
74. Takehara T, Liu X, Fujimoto J, Friedman SL and Takahashi H. (2001). Hepatology, 34, 55-61.
75. Taub R. (1996). FASEB J., 10, 413-427.
76. ten Dijke P, Miyazono K and Heldin CH. (2000). Trends Biochem. Sci., 25, 64-70.
77. Thiery JP. (2002). Nat. Rev. Cancer, 2, 442-454.
78. Wang XZ, Kuroda M, Sok J, Batchvarova N, Kimmel R, Chung P, Zinszner H and Ron D. (1998). EMBO J., 17, 3619-3630.
79. Wrana JL, Attisano L, Carcamo J, Zentella A, Doody J, Laiho M, Wang XF and Massague J. (1992). Cell, 71, 1003-1014.
80. Zhan Q, Lord KA, Alamo Jr I, Hollander MC, Carrier F, Ron D, Kohn KW, Hoffman B, Liebermann DA and Fornace Jr AJ. (1994). Mol. Cell. Biol., 14, 2361-2371.
81. Zhu W, Leber B and Andrews DW. (2001). EMBO J., 20, 5999-6007.
82. Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, Remotti H, Stevens JL and Ron D. (1998). Genes Dev., 12, 982-995.