Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-β1 and Ha-Ras: Steps towards invasiveness

Journal of Cell Science

Volumn 115, Issue 6, 2002, Pages 1189-1202

  Gotzmann, Josef ^a   Huber, Heidemarie ^a   Thallinger, Chrustiane ^a   Wolschek, Markus ^a   Jansen, Burkhard ^a   Schulte Hermann, Rolf ^a   Beug, Hartmut ^a   Mikulits, Wolfgang ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Epithelial polarity; Ha Ras; Hepatocytes; Invasive growth; TGF 1

Indexed keywords

COLLAGEN GEL; PHOSPHATIDYLINOSITOL 3 KINASE; REPRESSOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CANCER INHIBITION; CANCER INVASION; CELL CYCLE G1 PHASE; CELL GROWTH; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOSKELETON; ENZYME INHIBITION; EPITHELIUM CELL; FIBROBLAST; GENE ACTIVATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; LIVER CARCINOGENESIS; LIVER CELL; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; ONCOGENE H RAS; PHENOTYPE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TUMOR PROMOTION; TUMOR VASCULARIZATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AUTOCRINE COMMUNICATION; CADHERINS; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; EPITHELIUM; FIBROBLASTS; HEPATOCYTES; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEOPLASM INVASIVENESS; NEOPLASMS, EXPERIMENTAL; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS P21(RAS); TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

ANIMALIA; GASTROPODA; MURINAE;

EID: 0037087507     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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