Pharmacokinetics and tissue distribution of uraemic indoxyl sulphate in rats

Biopharmaceutics and Drug Disposition

Volumn 24, Issue 8, 2003, Pages 345-355

  Deguchi, Tsuneo ^a   Nakamura, Mikio ^a   Tsutsumi, Yasuhiro ^a   Suenaga, Ayaka ^a   Otagiri, Masaki ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Chronic renal failure; Indoxyl sulphate; Organic anion transporter; Uraemic toxin

Indexed keywords

ESTRONE SULFATE; INDICAN; PRASTERONE SULFATE; UREMIC TOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANION TRANSPORT; AREA UNDER THE CURVE; ARTICLE; BILIARY EXCRETION; BINDING AFFINITY; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; ELIMINATION REACTION; HALF LIFE TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; KIDNEY CLEARANCE; KIDNEY CORTEX SLICE; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE EXCRETION; MALE; NEPHRECTOMY; NONHUMAN; RAT; TISSUE DISTRIBUTION; TOXICOKINETICS; TRANSPORT KINETICS; UREMIA; URINARY EXCRETION;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; INDICAN; INFUSIONS, INTRAVENOUS; KIDNEY; KIDNEY FAILURE, CHRONIC; MALE; NEPHRECTOMY; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 0242456261     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdd.370     Document Type: Article

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