Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus

Molecular Pharmacology

Volumn 61, Issue 5, 2002, Pages 982-988

  Nagata, Yoshinori ^a,b   Kusuhara, Hiroyuki ^a,b   Endou, Hitoshi ^a,b   Sugiyama, Yuichi ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYORIN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOHIPPURIC ACID; ANION; CARRIER PROTEIN; CIMETIDINE; ESTRADIOL 17 GLUCURONIDE; OGRANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 3; ORGANIC COMPOUND; PENICILLIN G; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRUSH BORDER; CEREBROSPINAL FLUID; CHOROID PLEXUS; CONTROLLED STUDY; DETOXIFICATION; DRUG TRANSPORT; DRUG UPTAKE; IMMUNOHISTOCHEMISTRY; MALE; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; TRANSPORT KINETICS; WESTERN BLOTTING;

ANIMALS; CHOROID PLEXUS; CIMETIDINE; ENZYME INHIBITORS; MALE; ORGANIC ANION TRANSPORT PROTEIN 1; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; P-AMINOHIPPURIC ACID; PENICILLIN G; PENICILLINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036235889     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.61.5.982     Document Type: Article

References (35)

1. The choroid epithelium is the site of the organic anion transport protein in the brain
2. Multispecific amphipathic substrate transport by an organic anion transporter of human liver
3. Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney
4. Transporters involved in the elimination of drugs in the kidney: Organic anion transporters and organic cation transporters
5. Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells
6. Organic anion-transporting polypeptides mediate transport of opioid peptides across blood-brain barrier
7. Organic anion transport across the choroid plexus
8. Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain
9. Brain drug delivery, drug metabolism, and multidrug resistance at the choroid plexus
10. Active transport properties of porcine choroid plexus cells in culture
11. Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions
12. Porcine choroid plexus epithelial cells in culture: Regulation of barrier properties and transport process
13. Cellular and molecular aspects of drug transport in the kidney
14. The interaction and transport of β-lactam antibiotics with the cloned rat renal organic anion transporter 1
15. Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain
16. Efflux transport systems for drugs at the blood-brain barrier and blood-cerebrospinal fluid barrier
17. Oatp2 mediates bidirectional organic solute transport: A role for intracellular glutathione
18. +-ATPase distributions in polarized epithelia
19. Molecular aspects of hepatobiliary transport
20. Transepithelial transport of organic anions across the choroid plexus: Possible involvement of organic anion transporter and multidrug resistance-associated protein
21. Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct
22. Mechanism of organic anion transport across the apical membrane of choroid plexus
23. Transport of nutrients across the choroid plexus
24. The multispecific organic anion transporter (OAT) family
25. Expression cloning and characterization of a novel multispecific organic anion transporter
26. Drug transport in the mammalian central nervous system: Multiple complex systems. A critical analysis and commentary
27. Characterization of the efflux transport of 17β-estradiol-D-17β-glucuronide from the brain across the blood-brain barrier
28. Transport of cimetidine by the rat choroid-plexus in vitro
29. Transport of benzylpenicillin by the rat choriod plexus in vivo
30. Role of efflux transport across the blood-brain barrier and blood cerebrospinal fluid barrier on the disposition of xenobiotics in the central nervous system
31. Localization of an organic anion transporter-GFP fusion construct (rROAT1-GFP) in intact proximal tubules
32. Molecular pharmacology of renal organic anion transporters
33. Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis
34. Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier
35. A pharmokinetic analysis program (MULTI) for microcomputer