Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake

British Journal of Pharmacology

Volumn 135, Issue 2, 2002, Pages 555-563

  Motojima, Masaru ^a,b   Hosokawa, Atsuko ^b   Yamato, Hideyuki ^b   Muraki, Takamura ^a   Yoshioka, Toshimasa ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b KUREHA CORPORATION   (Japan)

Author keywords

Cell injury; Free radical; Organic anion transporter; Renal proximal tubules; Uraemic toxins

Indexed keywords

4 HYDROXYHIPPURIC ACID; ANTIOXIDANT; ANTIPORTER; FREE RADICAL; HIPPURIC ACID; HUMAN ORGANIC ANION TRANSPORTER 1; INDICAN; INDOLEACETIC ACID; PROBENECID; SALICYLURIC ACID; UNCLASSIFIED DRUG; UREMIC TOXIN;

ANIMAL CELL; ANION TRANSPORT; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CYTOTOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE DAMAGE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; BINDING SITES; CELL LINE; CELL LINE, TRANSFORMED; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICALS; GROWTH INHIBITORS; HUMANS; KIDNEY TUBULES, PROXIMAL; OPOSSUMS; ORGANIC ANION TRANSPORT PROTEIN 1; P-AMINOHIPPURIC ACID; RATS; TOXINS, BIOLOGICAL; UREMIA;

EID: 0036179812     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704482     Document Type: Article

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