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Volumn 282, Issue 1-2, 2003, Pages 175-186

In-cell generation of antibody single-chain Fv transcripts by targeted RNA trans-splicing

Author keywords

Monoclonal antibodies; RNA trans splicing; Variable region genes

Indexed keywords

RNA; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

EID: 0242321277     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2003.08.006     Document Type: Article
Times cited : (3)

References (36)
  • 2
    • 0023090954 scopus 로고
    • Transcriptional control of mu- and kappa-gene expression in resting and bacterial lipopolysaccharide-activated normal B cells
    • Chen-Bettecken U., Wecker E., Schimpl A. Transcriptional control of mu- and kappa-gene expression in resting and bacterial lipopolysaccharide-activated normal B cells. Immunobiology. 174:1987;162-176.
    • (1987) Immunobiology , vol.174 , pp. 162-176
    • Chen-Bettecken, U.1    Wecker, E.2    Schimpl, A.3
  • 7
    • 0026743196 scopus 로고
    • In-cell PCR from mRNA: Amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells
    • Embleton M.J., Gorochov G., Jones P.T., Winter G. In-cell PCR from mRNA: amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells. Nucleic Acids Res. 20:1992;3831-3837.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 3831-3837
    • Embleton, M.J.1    Gorochov, G.2    Jones, P.T.3    Winter, G.4
  • 8
    • 0030587822 scopus 로고    scopus 로고
    • Multiple types of chimeric germ-line Ig heavy chain transcripts in human B cells: Evidence for trans-splicing of human Ig RNA
    • Fujieda S., Lin Y.Q., Saxon A., Zhang K. Multiple types of chimeric germ-line Ig heavy chain transcripts in human B cells: evidence for trans-splicing of human Ig RNA. J. Immunol. 157:1996;3450-3459.
    • (1996) J. Immunol. , vol.157 , pp. 3450-3459
    • Fujieda, S.1    Lin, Y.Q.2    Saxon, A.3    Zhang, K.4
  • 9
    • 0026331294 scopus 로고
    • Regulated expression of immunoglobulin trans-mRNA consisting of the variable region of a transgenic mu chain and constant regions of endogenous isotypes
    • Han H., Okamoto M., Honjo T., Shimizu A. Regulated expression of immunoglobulin trans-mRNA consisting of the variable region of a transgenic mu chain and constant regions of endogenous isotypes. Int. Immunol. 3:1991;1197-1206.
    • (1991) Int. Immunol. , vol.3 , pp. 1197-1206
    • Han, H.1    Okamoto, M.2    Honjo, T.3    Shimizu, A.4
  • 10
    • 0030866432 scopus 로고    scopus 로고
    • Evaluating and enhancing ribozyme reaction efficiency in mammalian cells
    • Jones J.T., Sullenger B.A. Evaluating and enhancing ribozyme reaction efficiency in mammalian cells. Nat. Biotechnol. 15:1997;902-905.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 902-905
    • Jones, J.T.1    Sullenger, B.A.2
  • 11
    • 0029896544 scopus 로고    scopus 로고
    • Tagging ribozyme reaction sites to follow trans-splicing in mammalian cells
    • Jones J.T., Lee S.W., Sullenger B.A. Tagging ribozyme reaction sites to follow trans-splicing in mammalian cells. Nat. Med. 2:1996;643-648.
    • (1996) Nat. Med. , vol.2 , pp. 643-648
    • Jones, J.T.1    Lee, S.W.2    Sullenger, B.A.3
  • 12
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler G., Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 256:1975;495-497.
    • (1975) Nature , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 13
    • 0017135663 scopus 로고
    • Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion
    • Kohler G., Milstein C. Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion. Eur. J. Immunol. 6:1976;511-519.
    • (1976) Eur. J. Immunol. , vol.6 , pp. 511-519
    • Kohler, G.1    Milstein, C.2
  • 14
    • 0022376562 scopus 로고
    • Trans splicing of mRNA precursors in vitro
    • Konarska M.M., Padgett R.A., Sharp P.A. Trans splicing of mRNA precursors in vitro. Cell. 42:1985;165-171.
    • (1985) Cell , vol.42 , pp. 165-171
    • Konarska, M.M.1    Padgett, R.A.2    Sharp, P.A.3
  • 15
    • 0036792889 scopus 로고    scopus 로고
    • A general role for splicing enhancers in exon definition
    • Lam B.J., Hertel K.J. A general role for splicing enhancers in exon definition. RNA. 8:2002;1233-1241.
    • (2002) RNA , vol.8 , pp. 1233-1241
    • Lam, B.J.1    Hertel, K.J.2
  • 16
    • 0025102021 scopus 로고
    • Expression of T cell antigen receptor heterodimers in a lipid-linked form
    • Lin A.Y., Devaux B., Green A., Sagerstrom C., Elliott J.F., Davis M.M. Expression of T cell antigen receptor heterodimers in a lipid-linked form. Science. 249:1990;677-679.
    • (1990) Science , vol.249 , pp. 677-679
    • Lin, A.Y.1    Devaux, B.2    Green, A.3    Sagerstrom, C.4    Elliott, J.F.5    Davis, M.M.6
  • 19
    • 0031775443 scopus 로고    scopus 로고
    • The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus
    • Matsuda F., Ishii K., Bourvagnet P., Kuma K., Hayashida H., Miyata T., Honjo T. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. J. Exp. Med. 188:1998;2151-2162.
    • (1998) J. Exp. Med. , vol.188 , pp. 2151-2162
    • Matsuda, F.1    Ishii, K.2    Bourvagnet, P.3    Kuma, K.4    Hayashida, H.5    Miyata, T.6    Honjo, T.7
  • 21
    • 0026570150 scopus 로고
    • Coexpression of mu and gamma 1 heavy chains can occur by a discontinuous transcription mechanism from the same unrearranged chromosome
    • Nolan-Willard M., Berton M.T., Tucker P. Coexpression of mu and gamma 1 heavy chains can occur by a discontinuous transcription mechanism from the same unrearranged chromosome. Proc. Natl. Acad. Sci. U. S. A. 89:1992;1234-1238.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 1234-1238
    • Nolan-Willard, M.1    Berton, M.T.2    Tucker, P.3
  • 22
    • 0020681250 scopus 로고
    • Transfer of a cloned immunoglobulin light-chain gene to mutant hybridoma cells restores specific antibody production
    • Ochi A., Hawley R.G., Shulman M.J., Hozumi N. Transfer of a cloned immunoglobulin light-chain gene to mutant hybridoma cells restores specific antibody production. Nature. 302:1983;340-342.
    • (1983) Nature , vol.302 , pp. 340-342
    • Ochi, A.1    Hawley, R.G.2    Shulman, M.J.3    Hozumi, N.4
  • 23
    • 0031431812 scopus 로고    scopus 로고
    • The spatial distribution of human immunoglobulin genes within the nucleus: Evidence for gene topography independent of cell type and transcriptional activity
    • Parreira L., Telhada M., Ramos C., Hernandez R., Neves H., Carmo-Fonseca M. The spatial distribution of human immunoglobulin genes within the nucleus: evidence for gene topography independent of cell type and transcriptional activity. Hum. Genet. 100:1997;588-594.
    • (1997) Hum. Genet. , vol.100 , pp. 588-594
    • Parreira, L.1    Telhada, M.2    Ramos, C.3    Hernandez, R.4    Neves, H.5    Carmo-Fonseca, M.6
  • 24
    • 0031940035 scopus 로고    scopus 로고
    • Ribozyme-mediated trans-splicing of a trinucleotide repeat
    • Phylactou L.A., Darrah C., Wood M.J. Ribozyme-mediated trans-splicing of a trinucleotide repeat. Nat. Genet. 18:1998;378-381.
    • (1998) Nat. Genet. , vol.18 , pp. 378-381
    • Phylactou, L.A.1    Darrah, C.2    Wood, M.J.3
  • 26
    • 0034889309 scopus 로고    scopus 로고
    • Messenger RNA repair and restoration of protein function by spliceosome-mediated RNA trans-splicing
    • Puttaraju M., DiPasquale J., Baker C.C., Mitchell L.G., Garcia-Blanco M.A. Messenger RNA repair and restoration of protein function by spliceosome-mediated RNA trans-splicing. Molec. Ther. 4:2001;105-114.
    • (2001) Molec. Ther. , vol.4 , pp. 105-114
    • Puttaraju, M.1    DiPasquale, J.2    Baker, C.C.3    Mitchell, L.G.4    Garcia-Blanco, M.A.5
  • 27
    • 0027454641 scopus 로고
    • Synthesis and regulation of trans-mRNA encoding the immunoglobulin epsilon heavy chain
    • Shimizu A., Honjo T. Synthesis and regulation of trans-mRNA encoding the immunoglobulin epsilon heavy chain. FASEB J. 7:1993;149-154.
    • (1993) FASEB J. , vol.7 , pp. 149-154
    • Shimizu, A.1    Honjo, T.2
  • 28
  • 29
    • 0025828378 scopus 로고
    • Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene
    • Shimizu A., Nussenzweig M.C., Han H., Sanchez M., Honjo T. Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene. J. Exp. Med. 173:1991;1385-1393.
    • (1991) J. Exp. Med. , vol.173 , pp. 1385-1393
    • Shimizu, A.1    Nussenzweig, M.C.2    Han, H.3    Sanchez, M.4    Honjo, T.5
  • 30
    • 0022386757 scopus 로고
    • Trans splicing of mRNA precursors
    • Solnick D. Trans splicing of mRNA precursors. Cell. 42:1985;157-164.
    • (1985) Cell , vol.42 , pp. 157-164
    • Solnick, D.1
  • 31
    • 0016437259 scopus 로고
    • Immunoglobulin heavy chain mRNA in mitogen-stimulated B cells
    • Stevens R.H., Askonas B.A., Welstead J.L. Immunoglobulin heavy chain mRNA in mitogen-stimulated B cells. Eur. J. Immunol. 5:1975;47-53.
    • (1975) Eur. J. Immunol. , vol.5 , pp. 47-53
    • Stevens, R.H.1    Askonas, B.A.2    Welstead, J.L.3
  • 32
    • 0027987902 scopus 로고
    • Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing
    • Sullenger B.A., Cech T.R. Ribozyme-mediated repair of defective mRNA by targeted, trans-splicing. Nature. 371:1994;619-622.
    • (1994) Nature , vol.371 , pp. 619-622
    • Sullenger, B.A.1    Cech, T.R.2
  • 33
    • 0026785856 scopus 로고
    • The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops
    • Tomlinson I.M., Walter G., Marks J.D., Llewelyn M.B., Winter G. The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J. Mol. Biol. 227:1992;776-798.
    • (1992) J. Mol. Biol. , vol.227 , pp. 776-798
    • Tomlinson, I.M.1    Walter, G.2    Marks, J.D.3    Llewelyn, M.B.4    Winter, G.5
  • 34
    • 0034682505 scopus 로고    scopus 로고
    • Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts
    • Watanabe T., Sullenger B.A. Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts. Proc. Natl. Acad. Sci. U. S. A. 97:2000;8490-8494.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 8490-8494
    • Watanabe, T.1    Sullenger, B.A.2
  • 36
    • 0028979795 scopus 로고
    • Germ-line human epsilon heavy chain gene RNA transcripts utilize the full range of alternative 3′ splicing seen in productive epsilon mRNA
    • Zhang K., Diaz-Sanchez D., Saxon A. Germ-line human epsilon heavy chain gene RNA transcripts utilize the full range of alternative 3′ splicing seen in productive epsilon mRNA. Immunology. 85:1995;228-235.
    • (1995) Immunology , vol.85 , pp. 228-235
    • Zhang, K.1    Diaz-Sanchez, D.2    Saxon, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.