메뉴 건너뛰기




Volumn 184, Issue SUPPL. 1, 2003, Pages 19-24

Therapeutic gene transfer with herpes-based vectors: Studies in Parkinson's disease and motor nerve regeneration

Author keywords

Gene therapy; Herpes simplex; Parkinson's disease; Peripheral nerve; Trauma

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; OXIDOPAMINE; PROTEIN BCL 2; VIRUS VECTOR;

EID: 0242302561     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4886(03)00358-3     Document Type: Article
Times cited : (16)

References (41)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams J.M., Cory S. The Bcl-2 protein family arbiters of cell survival . Science. 281:1998;1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 2
    • 0036581222 scopus 로고    scopus 로고
    • The GDNF family: Signalling, biological functions and therapeutic value
    • Airaksinen M.S., Saarma M. The GDNF family signalling, biological functions and therapeutic value . Nat. Rev. Neurosci. 3:2002;383-394.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 383-394
    • Airaksinen, M.S.1    Saarma, M.2
  • 3
    • 0028795044 scopus 로고
    • Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain
    • Beck K.D., Valverde J., Alexi T., Poulsen K., Moffat B., Vandlen R.A., Rosenthal A., Hefti F. Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature. 373:1995;339-341.
    • (1995) Nature , vol.373 , pp. 339-341
    • Beck, K.D.1    Valverde, J.2    Alexi, T.3    Poulsen, K.4    Moffat, B.5    Vandlen, R.A.6    Rosenthal, A.7    Hefti, F.8
  • 4
    • 0030795798 scopus 로고    scopus 로고
    • Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease
    • Bilang-Bleuel A., Revah F., Colin P., Locquet I., Robert J.J., Mallet J., Horellou P. Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease. Proc. Natl. Acad. Sci. USA. 94:1997;8818-8823.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8818-8823
    • Bilang-Bleuel, A.1    Revah, F.2    Colin, P.3    Locquet, I.4    Robert, J.J.5    Mallet, J.6    Horellou, P.7
  • 7
    • 0037057620 scopus 로고    scopus 로고
    • Regulators split on gene therapy as patient shows signs of cancer
    • Check E. Regulators split on gene therapy as patient shows signs of cancer. Nature. 419:2002;545-546.
    • (2002) Nature , vol.419 , pp. 545-546
    • Check, E.1
  • 10
    • 0022358365 scopus 로고
    • Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4
    • DeLuca N.A., McCarthy A.M., Schaffer P.A. Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J. Virol. 56:1985;558-570.
    • (1985) J. Virol. , vol.56 , pp. 558-570
    • DeLuca, N.A.1    McCarthy, A.M.2    Schaffer, P.A.3
  • 11
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
    • Earnshaw W.C., Martins L.M., Kaufmann S.H. Mammalian caspases structure, activation, substrates, and functions during apoptosis . Annu. Rev. Biochem. 68:1999;383-424.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 383-424
    • Earnshaw, W.C.1    Martins, L.M.2    Kaufmann, S.H.3
  • 13
    • 0344995285 scopus 로고    scopus 로고
    • Perturbation of cell cycle progression and cellular gene expression as a function of herpes simplex virus ICP0
    • Hobbs W.E. 2nd, DeLuca N.A. Perturbation of cell cycle progression and cellular gene expression as a function of herpes simplex virus ICP0. J. Virol. 73:1999;8245-8255.
    • (1999) J. Virol. , vol.73 , pp. 8245-8255
    • Hobbs II, W.E.1    DeLuca, N.A.2
  • 14
    • 0016162063 scopus 로고
    • Regulation of herpesvirus macromolecular synthesis I. Cascade regulation of the synthesis of three groups of viral proteins
    • Honess R.W., Roizman B. Regulation of herpesvirus macromolecular synthesis I. Cascade regulation of the synthesis of three groups of viral proteins. J. Virol. 14:1974;8-19.
    • (1974) J. Virol. , vol.14 , pp. 8-19
    • Honess, R.W.1    Roizman, B.2
  • 15
    • 0028874203 scopus 로고
    • GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo
    • Kearns C.M., Gash D.M. GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo. Brain Res. 672:1995;104-111.
    • (1995) Brain Res. , vol.672 , pp. 104-111
    • Kearns, C.M.1    Gash, D.M.2
  • 16
    • 0034659835 scopus 로고    scopus 로고
    • Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: Intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system
    • Kirik D., Rosenblad C., Bjorklund A., Mandel R.J. Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system . J. Neurosci. 20:2000;4686-4700.
    • (2000) J. Neurosci. , vol.20 , pp. 4686-4700
    • Kirik, D.1    Rosenblad, C.2    Bjorklund, A.3    Mandel, R.J.4
  • 18
    • 0032427040 scopus 로고    scopus 로고
    • Deletion of multiple immediate-early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neurons
    • Krisky D.M., Wolfe D., Goins W.F., Marconi P.C., Ramakrishnan R., Mata M., Rouse R.J., Fink D.J., Glorioso J.C. Deletion of multiple immediate-early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neurons. Gene Ther. 5:1998;1593-1603.
    • (1998) Gene Ther. , vol.5 , pp. 1593-1603
    • Krisky, D.M.1    Wolfe, D.2    Goins, W.F.3    Marconi, P.C.4    Ramakrishnan, R.5    Mata, M.6    Rouse, R.J.7    Fink, D.J.8    Glorioso, J.C.9
  • 19
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • Kroemer G., Reed J.C. Mitochondrial control of cell death. Nat. Med. 6:2000;513-519.
    • (2000) Nat. Med. , vol.6 , pp. 513-519
    • Kroemer, G.1    Reed, J.C.2
  • 20
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin L.F.H., Doherty D.H., Lile J.D., Bektesh S., Collins F. GDNF a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons . Science. 260:1993;1130-1132.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.H.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 21
    • 0032708890 scopus 로고    scopus 로고
    • Recombinant adeno-associated viral vector-mediated glial cell line-derived neurotrophic factor gene transfer protects nigral dopamine neurons after onset of progressive degeneration in a rat model of Parkinson's disease
    • Mandel R.J., Snyder R.O., Leff S.E. Recombinant adeno-associated viral vector-mediated glial cell line-derived neurotrophic factor gene transfer protects nigral dopamine neurons after onset of progressive degeneration in a rat model of Parkinson's disease. Exp. Neurol. 160:1999;205-214.
    • (1999) Exp. Neurol. , vol.160 , pp. 205-214
    • Mandel, R.J.1    Snyder, R.O.2    Leff, S.E.3
  • 22
    • 0031456051 scopus 로고    scopus 로고
    • Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats
    • Mandel R.J., Spratt S.K., Snyder R.O., Leff S.E. Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats. Proc. Natl. Acad. Sci. USA. 94:1997;14083-14088.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14083-14088
    • Mandel, R.J.1    Spratt, S.K.2    Snyder, R.O.3    Leff, S.E.4
  • 23
    • 0035066568 scopus 로고    scopus 로고
    • Genetically engineered human herpes simplex virus in the treatment of brain tumours
    • Markert J.M., Parker J.N., Gillespie G.Y., Whitley R.J. Genetically engineered human herpes simplex virus in the treatment of brain tumours. Herpes. 8:2001;17-22.
    • (2001) Herpes , vol.8 , pp. 17-22
    • Markert, J.M.1    Parker, J.N.2    Gillespie, G.Y.3    Whitley, R.J.4
  • 24
    • 0038054338 scopus 로고    scopus 로고
    • AAV serotype 2 vectors preferentially integrate into active genes in mice
    • Nakai H., Montini E., Fuess S., Storm T.A., Grompe M., Kay M.A. AAV serotype 2 vectors preferentially integrate into active genes in mice. Nat. Genet. 34:2003;297-302.
    • (2003) Nat. Genet. , vol.34 , pp. 297-302
    • Nakai, H.1    Montini, E.2    Fuess, S.3    Storm, T.A.4    Grompe, M.5    Kay, M.A.6
  • 25
    • 0034994657 scopus 로고    scopus 로고
    • Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA induced degeneration
    • Natsume A., Mata M., Goss J.R., Huang S., Wolfe D., Oligino T., Glorioso J.C., Fink D.J. Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA induced degeneration. Exp. Neurol. 169:2001;231-238.
    • (2001) Exp. Neurol. , vol.169 , pp. 231-238
    • Natsume, A.1    Mata, M.2    Goss, J.R.3    Huang, S.4    Wolfe, D.5    Oligino, T.6    Glorioso, J.C.7    Fink, D.J.8
  • 26
    • 0036158965 scopus 로고    scopus 로고
    • Bcl-2 and GDNF delivered by HSV-mediated gene transfer after spinal root avulsion provide a synergistic effect
    • Natsume A., Mata M., Wolfe D., Oligino T., Goss J., Huang S., Glorioso J., Fink D.J. Bcl-2 and GDNF delivered by HSV-mediated gene transfer after spinal root avulsion provide a synergistic effect. J. Neurotrauma. 19:2002;61-68.
    • (2002) J. Neurotrauma , vol.19 , pp. 61-68
    • Natsume, A.1    Mata, M.2    Wolfe, D.3    Oligino, T.4    Goss, J.5    Huang, S.6    Glorioso, J.7    Fink, D.J.8
  • 30
    • 0037096359 scopus 로고    scopus 로고
    • Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration
    • Palfi S., Leventhal L., Chu Y., Ma S.Y., Emborg M., Bakay R., Deglon N., Hantraye P., Aebischer P., Kordower J.H. Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration. J. Neurosci. 22:2002;4942-4954.
    • (2002) J. Neurosci. , vol.22 , pp. 4942-4954
    • Palfi, S.1    Leventhal, L.2    Chu, Y.3    Ma, S.Y.4    Emborg, M.5    Bakay, R.6    Deglon, N.7    Hantraye, P.8    Aebischer, P.9    Kordower, J.H.10
  • 31
    • 0034097605 scopus 로고    scopus 로고
    • Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model
    • Rosenblad C., Kirik D., Bjorklund A. Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model. Exp. Neurol. 161:2000;503-516.
    • (2000) Exp. Neurol. , vol.161 , pp. 503-516
    • Rosenblad, C.1    Kirik, D.2    Bjorklund, A.3
  • 32
    • 0030958819 scopus 로고    scopus 로고
    • The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27
    • Samaniego L.A., Wu N., DeLuca N.A. The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27. J. Virol. 71:1997;4614-4625.
    • (1997) J. Virol. , vol.71 , pp. 4614-4625
    • Samaniego, L.A.1    Wu, N.2    DeLuca, N.A.3
  • 33
    • 0028220834 scopus 로고
    • Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat
    • Sauer H., Oertel W.H. Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine a combined retrograde tracing and immunocytochemical study in the rat . Neuroscience. 59:1994;401-415.
    • (1994) Neuroscience , vol.59 , pp. 401-415
    • Sauer, H.1    Oertel, W.H.2
  • 34
    • 0029047329 scopus 로고
    • Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion
    • Sauer H., Rosenblad C., Bjorklund A. Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proc. Natl. Acad. Sci. USA. 92:1995;8935-8939.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8935-8939
    • Sauer, H.1    Rosenblad, C.2    Bjorklund, A.3
  • 35
  • 38
    • 0029793857 scopus 로고    scopus 로고
    • Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27 and ICP22
    • Wu N., Watkins S.C., Schaffer P.A., DeLuca N.A. Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27 and ICP22. J. Virol. 70:1996;6358-6368.
    • (1996) J. Virol. , vol.70 , pp. 6358-6368
    • Wu, N.1    Watkins, S.C.2    Schaffer, P.A.3    DeLuca, N.A.4
  • 39
    • 0035068196 scopus 로고    scopus 로고
    • Herpes simplex virus vector-mediated expression of Bcl-2 protects spinal motor neurons from degeneration following root avulsion
    • Yamada M., Natsume A., Mata M., Oligino T., Goss J., Glorioso J., Fink D.J. Herpes simplex virus vector-mediated expression of Bcl-2 protects spinal motor neurons from degeneration following root avulsion. Exp. Neurol. 168:2001;225-230.
    • (2001) Exp. Neurol. , vol.168 , pp. 225-230
    • Yamada, M.1    Natsume, A.2    Mata, M.3    Oligino, T.4    Goss, J.5    Glorioso, J.6    Fink, D.J.7
  • 40
    • 0033616576 scopus 로고    scopus 로고
    • Herpes simplex virus vector-mediated expression of Bcl-2 prevents 6-hydroxydopamine-induced degeneration of neurons in the substantia nigra in vivo
    • Yamada M., Oligino T., Mata M., Goss J.R., Glorioso J.C., Fink D.J. Herpes simplex virus vector-mediated expression of Bcl-2 prevents 6-hydroxydopamine-induced degeneration of neurons in the substantia nigra in vivo. Proc. Natl. Acad. Sci. USA. 96:1999;4078-4083.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4078-4083
    • Yamada, M.1    Oligino, T.2    Mata, M.3    Goss, J.R.4    Glorioso, J.C.5    Fink, D.J.6
  • 41
    • 0034189616 scopus 로고    scopus 로고
    • Replicating herpes simplex virus vectors for cancer gene therapy
    • Yeung S.N., Tufaro F. Replicating herpes simplex virus vectors for cancer gene therapy. Exp. Opin. Pharmacother. 1:2000;623-631.
    • (2000) Exp. Opin. Pharmacother. , vol.1 , pp. 623-631
    • Yeung, S.N.1    Tufaro, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.