CCAAT/Enhancer-Binding Protein-Homologous Protein Expression and Transcriptional Activity Are Regulated by 3′,5′-Cyclic Adenosine Monophosphate in Thyroid Cells

Molecular Endocrinology

Volumn 17, Issue 11, 2003, Pages 2283-2294

  Pomerance, Martine ^a   Carapau, Daniel ^a   Chantoux, Françoise ^a   Mockey, Michaël ^a   Correze, Claude ^a   Francon, Jacques ^a   Blondeau, Jean Paul ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CCAAT ENHANCER BINDING PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DERIVATIVE; FORSKOLIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; GENE CONTROL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEQUENCE HOMOLOGY; THYROID CELL; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANIMALS; ANTIOXIDANTS; BASE SEQUENCE; CARRIER PROTEINS; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; CYCLIC AMP; FORSKOLIN; GENE EXPRESSION REGULATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS (GENETICS); RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SYMPORTERS; THYROID GLAND; THYROTROPIN; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA; MAMMALIA;

EID: 0242267056     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2002-0400     Document Type: Article

References (53)

1. Garrington TP, Johnson GL 1999 Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr Opin Cell Biol 11:211-218
2. Dumont JE, Lamy F, Roger P, Maenhaut C 1992 Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors. Physiol Rev 72:667-697
3. Correze C, Blondeau JP, Pomerance M 2000 The thyrotropin receptor is not involved in the activation of p42/p44 mitogen-activated protein kinases by thyrotropin preparations in Chinese hamster ovary cells expressing the human thyrotropin receptor. Thyroid 10:747-752
4. Pomerance M, Abdullah HB, Kamerji S, Correze C, Blondeau JP 2000 Thyroid-stimulating hormone and cyclic AMP activate p38 mitogen-activated protein kinase cascade. Involvement of protein kinase A, rac1, and reactive oxygen species. J Biol Chem 275:40539-40546
5. Nebreda AR, Porras A 2000 p38 MAP kinases: beyond the stress response. Trends Biochem Sci 25:257-260
6. Nakamura K, Shirai T, Morishita S, Uchida S, Saeki-Miura K, Makishima F 1999 p38 Mitogen-activated protein kinase functionally contributes to chondrogenesis induced by growth/differentiation factor-5 in ATDC5 cells. Exp Cell Res 250:351-363
7. Zetser A, Gredinger E, Bengal E 1999 p38 Mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor. J Biol Chem 274:5193-5200
8. Iwasaki S, Iguchi M, Watanabe K, Hoshino R, Tsujimoto M, Kohno M 1999 Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2. J Biol Chem 274:26503-26510
9. Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Davis RJ 1996 MKK3-and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol 16:1247-1255
10. Jiang Y, Chen C, Li Z, Guo W, Gegner JA, Lin S, Han J 1996 Characterization of the structure and function of a new mitogen-activated protein kinase (p38β). J Biol Chem 271:17920-17926
11. Whitmarsh AJ, Yang SH, Su MS, Sharrocks AD, Davis RJ 1997 Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors. Mol Cell Biol 17:2360-2371
12. Janknecht R, Hunter T 1997 Convergence of MAP kinase pathways on the ternary complex factor Sap-1a. EMBO J 16:1620-1627
13. Tan Y, Rouse J, Zhang A, Cariati S, Cohen P, Comb MJ 1996 FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2. EMBO J 15:4629-4642
14. Heidenreich O, Neininger A, Schratt G, Zinck R, Cahill MA, Engel K, Kotlyarov A, Kraft R, Kostka S, Gaestel M, Nordheim A 1999 MAPKAP kinase 2 phosphorylates serum response factor in vitro and in vivo. J Biol Chem 274:14434-14443
15. Huang C, Ma WY, Maxiner A, Sun Y, Dong Z 1999 p38 Kinase mediates UV-induced phosphorylation of p53 protein at serine 389. J Biol Chem 274:12229-12235
16. Han J, Jiang Y, Li Z, Kravchenko W, Ulevitch RJ 1997 Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature 386:296-299
17. Zhao M, New L, Kravchenko VV, Kato Y, Gram H, di Padova F, Olson EN, Ulevitch RJ, Han J 1999 Regulation of the MEF2 family of transcription factors by p38. Mol Cell Biol 19:21-30
18. Engelman JA, Lisanti MP, Scherer PE 1998 Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis. J Biol Chem 273:32111-32120
19. Wang XZ, Ron D 1996 Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase. Science 272:1347-1349
20. Fornace Jr AJ, Alamo Jr I, Hollander MC 1988 DNA damage-inducible transcripts in mammalian cells. Proc Natl Acad Sci USA 85:8800-8804
21. Luethy JD, Holbrook NJ 1992 Activation of the gadd153 promoter by genotoxic agents: a rapid and specific response to DNA damage. Cancer Res 52:5-10
22. Ramji DP, Foka P 2002 CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem J 365:561-575
23. Brewer JW, Cleveland JL, Hendershot LM 1997 A pathway distinct from the mammalian unfolded protein response regulates expression of endoplasmic reticulum chaperones in non-stressed cells. EMBO J 16:7207-7216
24. Guyton KZ, Xu Q, Holbrook NJ 1996 Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element. Biochem J 314:547-554
25. Carlson SG, Fawcett TW, Bartlett JD, Bernier M, Holbrook NJ 1993 Regulation of the C/EBP-related gene gadd153 by glucose deprivation. Mol Cell Biol 13:4736-4744
26. Bruhat A, Jousse C, Wang XZ, Ron D, Ferrara M, Fafournoux P 1997 Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels. J Biol Chem 272:17588-17593
27. Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, Remotti H, Stevens JL, Ron D 1998 CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 12:982-995
28. Brenner B, Koppenhoefer U, Weinstock C, Linderkamp O, Lang F, Gulbins E 1997 Fas- or ceramide-induced apoptosis is mediated by a Rad1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153. J Biol Chem 272:22173-22181
29. Mertani HC, Zhu T, Goh EL, Lee KO, Morel G, Lobie PE 2001 Autocrine human growth hormone (hGH) regulation of human mammary carcinoma cell gene expression. Identification of CHOP as a mediator of hGH-stimulated human mammary carcinoma cell survival. J Biol Chem 276:21464-21475
30. Tang QQ, Lane MD 2000 Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhancer-binding protein-β during adipogenesis. Proc Natl Acad Sci USA 97:12446-12450
31. Maytin EV, Habener JF 1998 Transcription factors C/EBP alpha, C/EBP beta, and CHOP (Gadd153) expressed during the differentiation program of keratinocytes in vitro and in vivo. J Invest Dermatol 110:238-246
32. Coutts M, Cui K, Davis KL, Keutzer JC, Sytkowski AJ 1999 Regulated expression and functional role of the transcription factor CHOP (GADD153) in erythroid growth and differentiation. Blood 93:3369-3378
33. Ron D, Habener JF 1992 CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev 6:439-453
34. Ubeda M, Wang XZ, Zinszner H, Wu I, Habener JF, Ron D 1996 Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element. Mol Cell Biol 16:1479-1489
35. Enserink JM, Christensen AE, de Rooij J, van Triest M, Schwede F, Genieser HG, Doskeland SO, Blank JL, Bos JL 2002 A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK. Nat Cell Biol 4:901-906
36. Bjorkman U, Ekholm R 1992 Hydrogen peroxide generation and its regulation in FRTL-5 and porcine thyroid cells. Endocrinology 130:393-399
37. Guyton KZ, Xu Q, Holbrook NJ 1996 Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element. Biochem J 314:547-554
38. Entingh AJ, Law BK, Moses HL 2001 Induction of the C/EBP homologous protein (CHOP) by amino acid deprivation requires insulin-like growth factor I, phosphatidylinositol 3-kinase, and mammalian target of rapamycin signaling. Endocrinology 142:221-228
39. Ohno M, Zannini M, Levy O, Carrasco N, di Lauro R 1999 The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription. Mol Cell Biol 19:2051-2060
40. - symporter gene expression. Mol Endocrinol 12:727-736
41. Dell'Era P, Coco L, Ronca R, Sennino B, Presta M 2002 Gene expression profile in fibroblast growth factor 2-transformed endothelial cells. Oncogene 21:2433-2440
42. Talukder AH, Wang RA, Kumar R 2002 Expression and transactivating functions of the bZIP transcription factor GADD153 in mammary epithelial cells. Oncogene 21:4289-4300
43. Tramontano D, Moses AC, Veneziani BM, Ingbar SH 1988 Adenosine 3′,5′-monophosphate mediates both the mitogenic effect of thyrotropin and its ability to amplify the response to insulin-like growth factor I in FRTL5 cells. Endocrinology 122:127-132
44. Fawcett TW, Martindale JL, Guyton KZ, Hai T, Holbrook NJ 1999 Complexes containing activating transcription factor (ATF)/cAMP-responsive-element- binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response. Biochem J 339:135-141
45. Bruhat A, Jousse C, Carraro V, Reimold AM, Ferrara M, Fafournoux P 2000 Amino acids control mammalian gene transcription: activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter. Mol Cell Biol 20:7192-7204
46. Ubeda M, Vallejo M, Habener JF 1999 CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins. Mol Cell Biol 19:7589-7599
47. Pullen N, Thomas G 1997 The modular phosphorylation and activation of p70s6k. FEBS Lett 410:78-82
48. Cass LA, Meinkoth JL 1998 Differential effects of cyclic adenosine 3′,5′-monophosphate on p70 ribosomal S6 kinase. Endocrinology 139:1991-1998
49. Zhu T, Lobie PE 2000 Janus kinase 2-dependent activation of p38 mitogen-activated protein kinase by growth hormone. Resultant transcriptional activation of ATF-2 and CHOP, cytoskeletal re-organization and mitogenesis. J Biol Chem 275:2103-2114
50. Wang XS, Diener K, Manthey CL, Wang S, Rosenzweig B, Bray J, Delaney J, Cole CN, Chan-Hui PY, Mantlo N, Lichenstein HS, Zukowski M, Yao Z 1997 Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase. J Biol Chem 272:23668-23674
51. Wang XZ, Kuroda M, Sok J, Batchvarova N, Kimmel R, Chung P, Zinszner H, Ron D 1998 Identification of novel stress-induced genes downstream of chop. EMBO J 17:3619-3630
52. Kogai T, Endo T, Saito T, Miyazaki A, Kawaguchi A, Onaya T 1997 Regulation by thyroid-stimulating hormone of sodium/iodide symporter gene expression and protein levels in FRTL-5 cells. Endocrinology 138:2227-2232
53. Schaffner W, Weissmann C 1973 A rapid, sensitive, and specific method for the determination of protein in dilute solution. Anal Biochem 56:502-514