Differential effects of cyclic adenosine 3',5' monophosphate on p70 ribosomal S6 kinase

Endocrinology

Volumn 139, Issue 4, 1998, Pages 1991-1998

  Cass, Lisa A ^a   Meinkoth, Judy L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHOTRANSFERASE; RAPAMYCIN; THYROTROPIN;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME REGULATION; GROWTH REGULATION; HORMONAL REGULATION; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; RAT; THYROID CELL;

EID: 0031765123     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.4.5880     Document Type: Article

References (48)

1. Dumont JE, Lamy F, Roger P, Maenhaut C 1992 Physiological and pathological regulation of thyroid cell proliferation and differentiation by thryotropin and other factors. Physiol Rev 72:667-697
2. Kupperman E, Wen W, Meinkoth JL 1993 Inhibition of thyrotropin-stimulated DNA synthesis by microinjection of inhibitors of cellular ras and the cyclic AMP dependent protein kinase. Mol Cell Biol 13:4477-4484
3. Al-Alawi N, Rose DW, Buckmaster C, Ahn N, Rapp U, Meinkoth J, Feramisco JR 1995 TSH-induced mitogenesis is Ras dependent but appears to bypass the Raf-dependent cytoplasmic kinase cascade. Mol Cell Biol 15:1162-1168
4. Lamy F, Wilkin F, Baptist M, Posada J, Roger PP, Dumont JE 1993 Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway. J Biol Chem 268:8398-8401
5. Miller MJ, Prigent S, Kupperman E, Rioux L, Park S-H, Feramisco JR, White MA, Rutkowski JL, Meinkoth JL 1997 RalGDS functions in Ras- and cAMP-mediated growth stimulation. J Biol Chem 272:5600-5605
6. Saunier B, Tournier C, Jacquemin C, Pierre M 1995 Stimulation of Mitogen-activated protein kinase by thyrotropin in primary cultured human thyroid follicles. J Biol Chem 270:3693-3697
7. Burgering BMT, Bos JL 1995 Regulation of Ras-mediated signalling: more than one way to skin a cat. Trends Biochem Sci 20:18-22
8. Chou MM, Blenis J 1995 The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling. Curr Opin Cell Biol 7:806-814
9. s6k function is essential for G1 progression. Nature 363:170-172
10. Reinhard C, Fernandez A, Lamb NJC, Thomas G 1994 Nuclear localization of p85s6k: functional requirement for entry into S phase. EMBO J 13:1557-1565
11. Monfar M, Lemon KP, Grammer TC, Cheatham L, Chung J, Vlahos CJ, Blenis J 1995 Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP. Mol Cell Biol 15:326-337
12. Petritsch C, Woscholski R, Edelmann HML, Ballou LM 1995 Activation of p70 S6 kinase and erk-encoded mitogen-activated protein kinases is resistant to high cyclic nucleotide levels in Swiss 3T3 fibroblasts. J Biol Chem 270:26619-26625
13. Withers DJ, Bloom SR, Rozengurt E 1995 Dissociation of cAMP-stimulated mitogenesis from activation of the mitogen-activated protein kinase cascade in Swiss 3T3 cells. J Biol Chem 270:21411-21419
14. Raff MC, Hornby-Smith A, Brockes JP 1978 Cyclic AMP as a mitogenic signal for cultured Schwann cells. Nature 273:672-673
15. Raff MC, Abney E, Brockes JP, Homby-Smith A 1978 Schwarun cell growth factors. Cell 15:813-822
16. Rozengurt E 1982 Synergistic stimulation of DNA synthesis by cyclic AMP derivatives and growth factors in mouse Swiss 3T3 cells. J Cell Physiol 112:243-250
17. Rutkowski JL, Kirk CJ, Lerner MA, Tennekoon GI 1995 Purification and expansion of human Schwann cells in vitro. Nat Med 1:80-83
18. LaMorte V, Goldsmith A, Spiegel J, Meinkoth J, Feramisco J 1992 Inhibition of DNA synthesis in living cells by microinjection of Gi2 antibodies. J Biol Chem 267:691-694
19. Sturgill TW, Wu J 1991 Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6. Biochim Biophys Acta 1092:350-357
20. s6k: mechanism of activation and role in mitogenesis. Cancer Biol 5:255-260
21. Chung J, Kuo CJ, Crabtree GR, Blenis J 1992 Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kD S6 protein kinases. Cell 69:1227-1236
22. Dumont FJ, Su Q 1996 Mechanism of action of the immunosuppressant rapamycin. Life Sci 58:373-395
23. Kuo CJ, Chung J, Fiorentino DF, Flanagan WM, Blenis J, Crabtree GR 1992 Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature 358:70-73
24. Fantozzi DA, Harootunian AT, Wen W, Taylor SS, Feramisco JR, Tsien RY, Meinkoth JL 1994 The thermostable inhibitor of cAMP-dependent protein kinase enhances the rate of export of the kinase catalytic subunit from the nucleus. J Biol Chem 269:2676-2686
25. Meinkoth JL, Alberts AS, Went W, Fantozzi D, Taylor SS, Hagiwara M, Montminy M, Feramisco JR 1993 Signal transduction through the cAMP-dependent protein kinase. Mol Cell Biochem 127/128:179-186
26. Vlahos CJ, Matter WF, Hui KY, Brown RF 1994 A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269:5241-5248
27. Ui M, Okada T, Hazeki K, Hazeki O 1995 Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem Sci 20:303-307
28. Meinkoth JL, Ji Y, Taylor SS, Feramisco JR 1990 Dynamics of cyclic AMP dependent protein kinase distribution in living cells. Proc Natl Acad Sci USA 87:9595-9599
29. Hagiwara M, Brindle P, Harootunian A, Armstrong R, Rivier J, Vale W, Tsien R, Montminy MR 1993 Coupling of hormonal stimulation and transcription via the cyclic AMP-responsive factor CREB is rate limited by nuclear entry of protein kinase A. Mol Cell Biol 13:4852-4859
30. Janknecht R, Nordheim A 1996 Regulation of the c-fos promoter by the ternary complex factor Sap-1a and its coactivator CBP. Oncogene 12:1961-1969
31. Kato J, Matsuoka M, Polyak K, Massague J, Sherr CJ 1994 Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27kip1) of cylcin-dependent kinase 4 activation. Cell 79:487-496
32. Roger PP, Reuse S, Maenhaut C, Dumont JE 1995 Multiple facets of the modulation of growth by cAMP. Vitam Horm 51:59-191
33. McKenzie FR, Pouyssegur J 1996 cAMP-mediated growth inhibition in fibroblasts is not mediated via mitogen-activated protein (MAP) kinase (ERK) inhibition. J Biol Chem 271:13476-13483
34. Marshall MS 1943 Ras target proteins in eukaryotic cells. FASEB J 9:1311-1318
35. Downward J 1994 Regulating S6 kinase. Nature 371:378-379
36. Blenis J, Erikson RL 1984 Phosphorylation of the ribosomal protein S6 is elevated in cells tranformed by a variety of tumor viruses. J Virol 50:966-969
37. Ras. Nature 371:426-429
38. Sakaue M, Bowtell D, Kasuga M 1995 A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways. Mol Cell Biol 15:379-388
39. Chung J, Grammer TC, Lemon KP, Kazalukas A, Blenis J 1944 PDGF- and insulin-dependent pp70s6k activation mediated by phosphatidylinositol-3-OH-kinase. Nature 370:71-75
40. Dahl J, Freund R, Blenis J, Benjamin TL 1996 Studies of partially transforming polyomavirus mutants establish a role for phosphatidylinositol 3-kinase in activation of pp70 S6 kinase. Mol Cell Biol 16:2728-2735
41. Weng Q-P, Andrabi K, Klippel A, Kozlowski MT, Williams LT, Avruch J 1995 Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation. Proc Natl Acad Sci USA 92:5744-5748
42. Jiang H, Luo J-Q, Urano T, Frankel P, Lu Z, Foster DA, Feig LA 1995 Involvement of Ral GTPase in v-Src-induced phospholipase D activation. Nature 378:409-412
43. Park S-H, Weinberg RA 1995 A putative effector of Ral has homology to Rho/Rac GTPase activating proteins. Oncogene 11:2349-2355
44. Cantor SB, Urano T, Feig LA 1995 Identification and characterization of Ral-binding protein 1, a potential downtream target of Ral GTPases. Mol Cell Biol 15:4578-4584
45. Julien-Flores V, Dorseuil O, Romero F, Letourneur F, Saragosti S, Berger R, Tavitian A, Gacon G, Camonis JH 1995 Bridging Ral GTPase to Rho pathways. J Biol Chem 270:22473-22477
46. Chou MM, Blenis J 1996 The 70kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1. Cell 85:573-583
47. Franke TF, Kaplan DR, Cantley LC, Toker A 1997 Direct regulation of the Akt protooncogene product by phosphatidylinositol-3,4-bisphosphate. Science 275:665-668
48. Burgering BMT, Coffer PJ 1995 Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602