Effect of in vivo nitrate tolerance on hypersensitivity to NO donors after NO-synthase blockade

Canadian Journal of Physiology and Pharmacology

Volumn 80, Issue 11, 2002, Pages 1106-1118

  Ratz, Jodan D ^a   Adams, Michael A ^a   Bennett, Brian M ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Biotransformation; Glyceryl trinitrate; Hypertension; Nitric oxide; Tolerance

Indexed keywords

3 (2 CARBOXYMETHOXY 4 METHOXYPHENYL) 1 (3,4 METHYLENEDIOXYPHENYL) 5 PROPOXY 2 INDANCARBOXYLIC ACID; ENDOTHELIN 1; GLYCERYL TRINITRATE; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM;

ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG TRANSFORMATION; ENZYME ACTIVITY; HEMODYNAMICS; HYPERSENSITIVITY; HYPERTENSION; IN VIVO STUDY; MALE; MEAN ARTERIAL PRESSURE; METABOLITE; NITRATE METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT; VASODILATATION;

ANIMALS; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; ENZYME INHIBITORS; MALE; NITRATES; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036902539     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y02-141     Document Type: Article

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