-
1
-
-
0029995670
-
Thiazolidinediones in the treatment of insulin resistance and type II diabetes
-
Satiel A.R., Olefsky J.M. Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes. 45:1996;1661-1669.
-
(1996)
Diabetes
, vol.45
, pp. 1661-1669
-
-
Satiel, A.R.1
Olefsky, J.M.2
-
2
-
-
0026517631
-
Metabolic effect of new oral hypoglycemic agent CS-045 in NIDDM subjects
-
Suter S.L., Nolan J.J., Wallace P., Gumbiner B., Olefsky J.M. Metabolic effect of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care. 15:1992;193-203.
-
(1992)
Diabetes Care
, vol.15
, pp. 193-203
-
-
Suter, S.L.1
Nolan, J.J.2
Wallace, P.3
Gumbiner, B.4
Olefsky, J.M.5
-
3
-
-
0032005178
-
Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus: A randomized, double blind, placebo-controlled trial
-
Maggs D.G., Buchanan T.A., Burant C.F., Cline G., Gumbiner B., Hsueh W.A., Inzucchi S., Kelley D., Nolan J., Olefsky J.M., Polonsky K.S., Silver D., Valiquett T.R., Shulman G.I. Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus: a randomized, double blind, placebo-controlled trial. Ann. Intern. Med. 128:1998;176-185.
-
(1998)
Ann. Intern. Med.
, vol.128
, pp. 176-185
-
-
Maggs, D.G.1
Buchanan, T.A.2
Burant, C.F.3
Cline, G.4
Gumbiner, B.5
Hsueh, W.A.6
Inzucchi, S.7
Kelley, D.8
Nolan, J.9
Olefsky, J.M.10
Polonsky, K.S.11
Silver, D.12
Valiquett, T.R.13
Shulman, G.I.14
-
4
-
-
0027983920
-
Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
-
Nolan J.J., Ludvik B., Beerdsen P., Joyce M., Olefsky J.M. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. New Engl. J. Med. 331:1994;1188-1193.
-
(1994)
New Engl. J. Med.
, vol.331
, pp. 1188-1193
-
-
Nolan, J.J.1
Ludvik, B.2
Beerdsen, P.3
Joyce, M.4
Olefsky, J.M.5
-
5
-
-
0029016829
-
An antidiabetic thiazollidinedione is a high affinity ligand for peroxisome proliferatoractivated receptor γ (PPAR-γ)
-
Lehmann J.M., Moore L.B., Smith-Oliver T.A., Wilkison W.O., Wilson T.M., Kliewer S.A. An antidiabetic thiazollidinedione is a high affinity ligand for peroxisome proliferatoractivated receptor γ (PPAR-γ). J. Biol. Chem. 270:1995;12953-12956.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Wilson, T.M.5
Kliewer, S.A.6
-
6
-
-
0029994543
-
Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
-
Schoonjans K., Staels B., Auwerx J. Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression. J. Lipid Res. 37:1996;907-925.
-
(1996)
J. Lipid Res.
, vol.37
, pp. 907-925
-
-
Schoonjans, K.1
Staels, B.2
Auwerx, J.3
-
7
-
-
0029731662
-
Peroxisome proliferator-activated receptors: A nuclear receptor signaling pathway in lipid physiology
-
Lemerger T., Desvergne B., Wahli W. Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology. Ann. Rev. Cell Dev. Biol. 12:1996;335-363.
-
(1996)
Ann. Rev. Cell Dev. Biol.
, vol.12
, pp. 335-363
-
-
Lemerger, T.1
Desvergne, B.2
Wahli, W.3
-
8
-
-
0028972025
-
15-Deoxy-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR-γ
-
Forman B.M., Tontonoz P., Chen J., Brun R.P., Spiegelman B.M., Evans R.M. 15-Deoxy-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR-γ Cell. 83:1995;803-812.
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
9
-
-
0033287988
-
Cardiovascular disease in patients with diabetes: Clinical consideration
-
Gaba M.K., Gaba S., Clark L.T. Cardiovascular disease in patients with diabetes: clinical consideration. J. Assoc. Acad. Minorit. Physicians. 10:1999;15-22.
-
(1999)
J. Assoc. Acad. Minorit. Physicians
, vol.10
, pp. 15-22
-
-
Gaba, M.K.1
Gaba, S.2
Clark, L.T.3
-
10
-
-
0032540325
-
Oxidized LDL regulates macrophages gene expression through ligand activation of PPAR-γ
-
Nagy L., Tontonoz P., Alvarez J.G.A., Chen H., Evans R.M. Oxidized LDL regulates macrophages gene expression through ligand activation of PPAR-γ Cell. 93:1998;229-240.
-
(1998)
Cell
, vol.93
, pp. 229-240
-
-
Nagy, L.1
Tontonoz, P.2
Alvarez, J.G.A.3
Chen, H.4
Evans, R.M.5
-
11
-
-
0344333464
-
Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells
-
Marx N., Schonbeck U., Lazar M.A., Libby P., Plutzky J. Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells. Circ. Res. 83:1998;1097-1103.
-
(1998)
Circ. Res.
, vol.83
, pp. 1097-1103
-
-
Marx, N.1
Schonbeck, U.2
Lazar, M.A.3
Libby, P.4
Plutzky, J.5
-
12
-
-
0032587328
-
PPARγ activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression. PPARγ as a potential mediator in vascular disease
-
Marx N., Bourcier T., Sukhova G.K., Libby P., Plutzky J. PPARγ activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression. PPARγ as a potential mediator in vascular disease. Arterioscler. Thromb. Vasc. Biol. 19:1999;546-551.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 546-551
-
-
Marx, N.1
Bourcier, T.2
Sukhova, G.K.3
Libby, P.4
Plutzky, J.5
-
13
-
-
0034057069
-
Peroxisome proliferator-activated receptors in the cardiovascular system
-
Bishop-Bailey D. Peroxisome proliferator-activated receptors in the cardiovascular system. Br. J. Pharmacol. 129:2000;823-834.
-
(2000)
Br. J. Pharmacol.
, vol.129
, pp. 823-834
-
-
Bishop-Bailey, D.1
-
14
-
-
0031886864
-
The peroxisome proliferator-activated receptor-g is a negative regulator of macrophage activation
-
Ricote M., Li A.C., Willson T.M., Kelly C.J., Glass C.K. The peroxisome proliferator-activated receptor-g is a negative regulator of macrophage activation. Nature. 391:1998;79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
15
-
-
0034665060
-
Role for peroxisome proliferator-activated receptor-γ alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells
-
Lee H., Shi W., Tontonoz P., Wang S., Subbanagounder G., Hedrick C.C., Hama S., Borromeo C., Evans R.M., Berliner J.A., Nagy L. Role for peroxisome proliferator-activated receptor-γ alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells. Circ. Res. 87:2000;516-521.
-
(2000)
Circ. Res.
, vol.87
, pp. 516-521
-
-
Lee, H.1
Shi, W.2
Tontonoz, P.3
Wang, S.4
Subbanagounder, G.5
Hedrick, C.C.6
Hama, S.7
Borromeo, C.8
Evans, R.M.9
Berliner, J.A.10
Nagy, L.11
-
17
-
-
0013626594
-
Risk of thrombosis in human atherosclerotic plaques: Role of atherosclerotic plaques
-
Davies M.J., Richardson P.C., Wooolf N., Katz D.R., Mann J. Risk of thrombosis in human atherosclerotic plaques: role of atherosclerotic plaques. Lancet. 2:1989;941-944.
-
(1989)
Lancet
, vol.2
, pp. 941-944
-
-
Davies, M.J.1
Richardson, P.C.2
Wooolf, N.3
Katz, D.R.4
Mann, J.5
-
18
-
-
0024330373
-
Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques
-
Richard P.D., Davies M.J., Born G.V.R. Influence of plaque configuration and stress distribution on fissuring of coronary atherosclerotic plaques. Lancet. 2:1989;941-944.
-
(1989)
Lancet
, vol.2
, pp. 941-944
-
-
Richard, P.D.1
Davies, M.J.2
Born, G.V.R.3
-
19
-
-
0026641243
-
Collagen type I and III, collagen content, GAGs and mechanical strength of human atherosclerotic plaque caps: Span-wise variations
-
Burleigh M.C., Briggs A.D., Lendon C.L., Davies M.J., Born G.V., Richardson P.D. Collagen type I and III, collagen content, GAGs and mechanical strength of human atherosclerotic plaque caps: span-wise variations. Atherosclerosis. 96:1992;71-81.
-
(1992)
Atherosclerosis
, vol.96
, pp. 71-81
-
-
Burleigh, M.C.1
Briggs, A.D.2
Lendon, C.L.3
Davies, M.J.4
Born, G.V.5
Richardson, P.D.6
-
20
-
-
0029054734
-
Molecular bases of the acute coronary syndromes
-
Libby P. Molecular bases of the acute coronary syndromes. Circulation. 91:1995;2844-2850.
-
(1995)
Circulation
, vol.91
, pp. 2844-2850
-
-
Libby, P.1
-
21
-
-
0026896029
-
The matrix-degrading metalloproteinases
-
Matrisian L.M. The matrix-degrading metalloproteinases. BioEssays. 14:1992;455-463.
-
(1992)
BioEssays
, vol.14
, pp. 455-463
-
-
Matrisian, L.M.1
-
22
-
-
0028063408
-
Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
-
Galis Z.S., Suknova G.K., Lark M.W., Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J. Clin. Invest. 94:1995;2493-2503.
-
(1995)
J. Clin. Invest.
, vol.94
, pp. 2493-2503
-
-
Galis, Z.S.1
Suknova, G.K.2
Lark, M.W.3
Libby, P.4
-
23
-
-
0020074191
-
Collagen polymorphism in the normal and diseased blood vessel wall. Investigation of collagens types I, III and V
-
Morton L.F., Barnes M.J. Collagen polymorphism in the normal and diseased blood vessel wall. Investigation of collagens types I, III and V. Atherosclerosis. 42:1982;41-51.
-
(1982)
Atherosclerosis
, vol.42
, pp. 41-51
-
-
Morton, L.F.1
Barnes, M.J.2
-
24
-
-
0020615381
-
Quantitation of type I to type III collagen ratios in small samples of human tendon, blood vessels, and atherosclerotic plaques
-
Hanson A.N., Bentley J.P. Quantitation of type I to type III collagen ratios in small samples of human tendon, blood vessels, and atherosclerotic plaques. Anal. Biochem. 130:1983;32-40.
-
(1983)
Anal. Biochem.
, vol.130
, pp. 32-40
-
-
Hanson, A.N.1
Bentley, J.P.2
-
25
-
-
0032865511
-
Angiogenesis and the atherosclerotic carotid plaque: An association between symptomatology and plaque morphology
-
McCarthy M.J., Loftus I.M., Thompson M.M., Jones L., London N.J., Bell P.R., Naylor A.R., Brindle N.P. Angiogenesis and the atherosclerotic carotid plaque: an association between symptomatology and plaque morphology. J. Vasc. Surg. 30:1999;261-268.
-
(1999)
J. Vasc. Surg.
, vol.30
, pp. 261-268
-
-
McCarthy, M.J.1
Loftus, I.M.2
Thompson, M.M.3
Jones, L.4
London, N.J.5
Bell, P.R.6
Naylor, A.R.7
Brindle, N.P.8
-
26
-
-
0032698709
-
Oxidized LDL stimulates matrix metalloproteinase-1 expression in human vascular endothelial cells
-
Huang Y., Mironova M., Lopes-Virella M.F. Oxidized LDL stimulates matrix metalloproteinase-1 expression in human vascular endothelial cells. Arterioscler. Thromb. Vasc. Biol. 19:1999;2640-2647.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 2640-2647
-
-
Huang, Y.1
Mironova, M.2
Lopes-Virella, M.F.3
-
27
-
-
0035501248
-
Inhibition of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by troglitazone: A peroxisome proliferator-activated receptor-gamma (PPAR gamma)-independent, antioxidant-related mechanism
-
Davis G.F., Khandelwal R.L., Wu L., Juurlink B.H., Roesler W.J. Inhibition of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by troglitazone: a peroxisome proliferator-activated receptor-gamma (PPAR gamma)-independent, antioxidant-related mechanism. Biochem. Pharmacol. 62:2001;1071-1079.
-
(2001)
Biochem. Pharmacol.
, vol.62
, pp. 1071-1079
-
-
Davis, G.F.1
Khandelwal, R.L.2
Wu, L.3
Juurlink, B.H.4
Roesler, W.J.5
-
28
-
-
0032602367
-
Expression of monocyte chemotactic protein-1 precedes monocyte recruitment in a rat model of acute liver injury, and is modulated by vitamin E
-
Marra F., DeFranco R., Grappone C., Parola M., Milani S., Leonarduzzi G., Pastacaldi S., Wenzel U.O., Pinzani M., Dianzani M.U., Laffi G., Gentilini P. Expression of monocyte chemotactic protein-1 precedes monocyte recruitment in a rat model of acute liver injury, and is modulated by vitamin E. J. Invest. Med. 47:1999;66-75.
-
(1999)
J. Invest. Med.
, vol.47
, pp. 66-75
-
-
Marra, F.1
DeFranco, R.2
Grappone, C.3
Parola, M.4
Milani, S.5
Leonarduzzi, G.6
Pastacaldi, S.7
Wenzel, U.O.8
Pinzani, M.9
Dianzani, M.U.10
Laffi, G.11
Gentilini, P.12
-
30
-
-
0031870652
-
Macrophages in human atheroma contain PPARγ: Differentiation- dependent PPARγ expression and reduction of MMP-9 activity through PPARγ activation in mononuclear phagocytes
-
Marx N., Sukhova G., Murphy C., Libby P., Plutzky J. Macrophages in human atheroma contain PPARγ: differentiation-dependent PPARγ expression and reduction of MMP-9 activity through PPARγ activation in mononuclear phagocytes. Am. J. Pathol. 153:1998;17-23.
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 17-23
-
-
Marx, N.1
Sukhova, G.2
Murphy, C.3
Libby, P.4
Plutzky, J.5
-
31
-
-
0034614270
-
Activation of PPAR alpha or gamma reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells
-
Shu H., Wong B., Zhou G., Li Y., Berger J., Woods J.W., Wright S.D., Cai T.O. Activation of PPAR alpha or gamma reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells. Biochem. Biophys. Res. Commun. 267:2000;345-349.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.267
, pp. 345-349
-
-
Shu, H.1
Wong, B.2
Zhou, G.3
Li, Y.4
Berger, J.5
Woods, J.W.6
Wright, S.D.7
Cai, T.O.8
-
32
-
-
0034668205
-
Role of the peroxisome proliferator-activated receptor (PPAR) in atherosclerosis
-
Neve B.P., Fruchart J., Staels B. Role of the peroxisome proliferator-activated receptor (PPAR) in atherosclerosis. Biochem. Pharmacol. 60:2000;1245-1250.
-
(2000)
Biochem. Pharmacol.
, vol.60
, pp. 1245-1250
-
-
Neve, B.P.1
Fruchart, J.2
Staels, B.3
-
33
-
-
0035124186
-
New oral therapies for type 2 diabetes mellitus: The glitazones or insulin sensitizers
-
Mudaliar S., Henry R.R. New oral therapies for type 2 diabetes mellitus: the glitazones or insulin sensitizers. Annu. Rev. Med. 52:2001;239-257.
-
(2001)
Annu. Rev. Med.
, vol.52
, pp. 239-257
-
-
Mudaliar, S.1
Henry, R.R.2
-
34
-
-
0034647567
-
The effects of thiazolidinediones on vascular smooth muscle cell activation by angiotensin II
-
Hattori Y., Akimoto K., Kasai K. The effects of thiazolidinediones on vascular smooth muscle cell activation by angiotensin II. Biochem. Biophys. Res. Commun. 273:2000;1144-1149.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.273
, pp. 1144-1149
-
-
Hattori, Y.1
Akimoto, K.2
Kasai, K.3
-
35
-
-
0033954725
-
In vitro inhibitory effects of troglitazone and its metabolites on drug oxidation activities of human cytochrome P450 enzymes: Comparison with pioglitazone and rosiglitazone
-
Yamazaki H., Suzuki M., Tane K., Shimada N., Nakajima M., Yokoi T. In vitro inhibitory effects of troglitazone and its metabolites on drug oxidation activities of human cytochrome P450 enzymes: comparison with pioglitazone and rosiglitazone. Xenobiotica. 30:2000;61-70.
-
(2000)
Xenobiotica
, vol.30
, pp. 61-70
-
-
Yamazaki, H.1
Suzuki, M.2
Tane, K.3
Shimada, N.4
Nakajima, M.5
Yokoi, T.6
-
36
-
-
0033004825
-
Differential effects of insulin-sensitizers troglitazone and rosiglitazone on ion currents in rat vascular myocytes
-
Knock G.A., Mishra S.K., Aaronson P.I. Differential effects of insulin-sensitizers troglitazone and rosiglitazone on ion currents in rat vascular myocytes. Eur. J. Pharmacol. 368:1999;103-109.
-
(1999)
Eur. J. Pharmacol.
, vol.368
, pp. 103-109
-
-
Knock, G.A.1
Mishra, S.K.2
Aaronson, P.I.3
-
37
-
-
0142043096
-
Insulin sensitizer troglitazone stimulates matrix metalloproteinase-1 expression in human vascular endothelial cells
-
Xu M., Game B.A., Lopes-Virella M.F., Huang Y. Insulin sensitizer troglitazone stimulates matrix metalloproteinase-1 expression in human vascular endothelial cells. Diabetes. 50:(Suppl. 2):2000;690.
-
(2000)
Diabetes
, vol.50
, Issue.SUPPL. 2
, pp. 690
-
-
Xu, M.1
Game, B.A.2
Lopes-Virella, M.F.3
Huang, Y.4
-
38
-
-
0031040745
-
The effect of alpha-tocopherol on proliferation, protein kinase C activity and gene expression in different cell lines
-
Fazzio A., Marilley D., Azzi A. The effect of alpha-tocopherol on proliferation, protein kinase C activity and gene expression in different cell lines. Biochem. Mol. Biol. Int. 41:1997;93-101.
-
(1997)
Biochem. Mol. Biol. Int.
, vol.41
, pp. 93-101
-
-
Fazzio, A.1
Marilley, D.2
Azzi, A.3
-
39
-
-
9844230954
-
Troglitazone increases the resistance of low density lipoprotein to oxidation in healthy volunteers
-
Cominacini L., Young M.M., Capriati A., Garbin U., Fratta Pasini A., Campagnola M., Davoli A., Rigoni A., Contessi G.B., Lo Cascio V. Troglitazone increases the resistance of low density lipoprotein to oxidation in healthy volunteers. Diabetologia. 40:1997;1211-1218.
-
(1997)
Diabetologia
, vol.40
, pp. 1211-1218
-
-
Cominacini, L.1
Young, M.M.2
Capriati, A.3
Garbin, U.4
Fratta Pasini, A.5
Campagnola, M.6
Davoli, A.7
Rigoni, A.8
Contessi, G.B.9
Lo Cascio, V.10
-
40
-
-
0032850352
-
Clinical pharmacokinetics of troglitazone
-
Loi C., Young M., Randinitis E., Vassos A., Koup J.R. Clinical pharmacokinetics of troglitazone. Clin. Pharmacokinet. 37:1999;91-104.
-
(1999)
Clin. Pharmacokinet.
, vol.37
, pp. 91-104
-
-
Loi, C.1
Young, M.2
Randinitis, E.3
Vassos, A.4
Koup, J.R.5
-
41
-
-
0032834055
-
EIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
-
Gingras A., Raught B., Sonenberg N. eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu. Rev. Biochem. 68:1999;913-963.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 913-963
-
-
Gingras, A.1
Raught, B.2
Sonenberg, N.3
-
43
-
-
0008861608
-
Disposition and metabolism of the new oral antidiabetic drug troglitazone in rats, mice and dogs
-
Kawai K., Kawasaki-Tokui Y., Odaka T., Tsuruta F., Kazui M., Iwabuchi H., Nakamura T., Kinoshita T., Ikeda T., Yoshioka T., Komai T., Nakamura K. Disposition and metabolism of the new oral antidiabetic drug troglitazone in rats, mice and dogs. Arzneimettel Forschung. 47:1997;356-368.
-
(1997)
Arzneimettel Forschung
, vol.47
, pp. 356-368
-
-
Kawai, K.1
Kawasaki-Tokui, Y.2
Odaka, T.3
Tsuruta, F.4
Kazui, M.5
Iwabuchi, H.6
Nakamura, T.7
Kinoshita, T.8
Ikeda, T.9
Yoshioka, T.10
Komai, T.11
Nakamura, K.12
|