Differential effects of insulin-sensitizers troglitazone and rosiglitazone on ion currents in rat vascular myocytes

European Journal of Pharmacology

Volumn 368, Issue 1, 1999, Pages 103-109

  Knock, Gregory A ^a   Mishra, Santosh K ^a   Aaronson, Philip I ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Ca2+ current; K+ current; Rosiglitazone; Smooth muscle, vascular; Troglitazone

Indexed keywords

ROSIGLITAZONE; THIAZOLIDINE DERIVATIVE; TROGLITAZONE;

ANIMAL TISSUE; AORTA; ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; IN VITRO STUDY; ION TRANSPORT; LUNG ARTERY; MALE; NONHUMAN; PATCH CLAMP; POTASSIUM TRANSPORT; PRIORITY JOURNAL; RAT; VASCULAR SMOOTH MUSCLE;

EID: 0033004825     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00020-5     Document Type: Article

References (27)

1. + current in rabbit vascular smooth muscle cells. Am. J. Physiol. 268:1995;H926-H934.
2. Bean B.P. Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state. Proc. Natl. Acad. Sci. U.S.A. 81:1984;6388-6392.
3. Buchanan T.A., Meehan W.P., Jeng Y.Y., Yang D., Chan T.M., Nadler J.L., Scott S., Rude R.K., Hseuh W.A. Blood pressure lowering by pioglitazone: evidence for a direct vascular effect. J. Clin. Invest. 96:1995;354-360.
4. Cobb J., Kliewer S., Lehmann J., Blanchard S., Parks D., Moore L., Lenhard J., Beck K., Thomson S. Troglitazone is a peroxisome proliferator activated receptor γ agonist: a novel mechanism for an antidiabetic agent. Diabetologia. 40:1997;A314. Suppl. 1.
5. Fujiwara T., Ohsawa T., Miyamoto M., Ushiyama S., Matsuda K., Horikoshi H. Troglitazone (CS-045) acutely increases skin blood flow in dexamethasone-induced diabetic obese Zucher rats and normal rats. Diabetes. 44:1995;72A. Suppl. 1.
6. The Troglitazone Study Group, Ghazzi M.N., Perez J.E., Antonucci T.K., Driscoll J.H., Huang S.M., Faja B.W., Whitcomb R.W. Cardiac and glycaemic benefits of troglitazone treatment in NIDDM. Diabetes. 46:1997;433-439.
7. Hoffman C.A., Colca J.R. New oral thiazolidinedione antidiabetic agents act is insulin sensitizers. Diabetes Care. 15(8):1992;1075-1077.
8. + channels in vascular smooth muscle cells. F.E.B.S. Lett. 297:1992;24-28.
9. Knaus H.-G., McManus O.B., Lee S.H., Schmalhofer W.A., Garcia-Calvo M., Helms L.M.H., Sanchez M., Giangiacomo K., Reuben J.P., Smith A.B. III, Kaczorowiski G.J., Garcia M.L. Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels. Biochemistry. 33:1994;5819-5828.
10. Kotchen T.A., Zhang H.Y., Reddy S., Hoffmann R.G. Effect of pioglitazone on vascular reactivity in vivo and in vitro. Am. J. Physiol. 270:1996;R660-R666.
11. ATP channel activity by troglitazone in CRI-G1 insulin-secreting cells. Eur. J. Pharmacol. 313:1996;163-167.
12. Nakamura Y., Ohya Y., Onaka H., Fujii K., Abe I. Inhibitory action of insulin-sensitizing agents on calcium channels in smooth muscle cells from resistance arteries of guinea-pig. Br. J. Pharmacol. 123:1998;675-682.
13. Nelson M.T., Quayle J.M. Physiological roles and properties of potassium channels in arterial smooth muscle. Am. J. Physiol. 268:1995;C799-C822.
14. Ogihara T., Rakugi H., Ikegami H., Mikami H., Masuo K. Enhancement of insulin sensitivity by troglitazone lowers blood pressure in diabetic hypertensives. Am. J. Hypertens. 8:1995;316-320.
15. Pershadsingh H.A., Szollosi J., Benson S., Hyun W.C., Feuerstein B.G., Kurtz T.W. Effects of ciglitazone on blood pressure and intracellular calcium metabolism. Hypertension. 21:1993;1020-1023.
16. Quignard J.-F., Grazzini E., Guillon G., Harricane M.-C., Nargeot J., Richard S. Absence of calcium channels in neonatal rat aortic myocytes. Pflug. Arch. Eur. J. Physiol. 431:1996;791-793.
17. Saltiel A.R., Olefsky J.M. Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes. 45:1996;1661-1669.
18. Sanguinetti M.C., Kass R.S. Voltage-dependent block of calcium channel current in the calf cardiac purkinje fiber by dihydropyridine calcium channel antagonists. Circ. Res. 55:1984;336-348.
19. + current in rat pulmonary arterial myocytes: structural aspects and involvement of protein kinase C. Circ. Res. 79:1996;20-31.
20. + current in rat pulmonary artery muscle cells. Am. J. Physiol. 266:1994;H265-H370.
21. 2+ currents and not endothelial nitric oxide production. Diabetes. 46:1997;659-664.
22. Uehara A., Hume J.R. Interaction of organic calcium channel antagonists with calcium channels in single frog atrial cells. J. Gen. Physiol. 85:1985;621-648.
23. Walker A.B., Naderali E.K., Chattington P.D., Buckingham R.E., Williams G. Differential vasoactive effects of the insulin-sensitizers rosiglitazone (BRL 49653) and troglitazone on human small arteries in vitro. Diabetes. 47(5):1998;810-820.
24. Yasunari K., Kohno M., Kano H., Yokokawa K., Minami M., Yoshikawa J. Mechanisms of action of troglitazone in the prevention of high glucose-induced migration and proliferation of cultured coronary smooth muscle cells. Circ. Res. 81:1997;953-962.
25. Yoshioka S., Nishino H., Shiraki T., Ikeda K., Kioke H., Okuno A., Wada M., Fujiwara T., Horikoshi H. Antihypertensive effects of CS-045 treatment in obese Zucher rats. Metabolism. 42:1993;75-80.
26. Yuan X.-J., Goldman W., Tod M.L., Rubin L.J., Blaustein M.P. Hypoxia reduces potassium current in cultured rat pulmonary but not mesenteric arterial myocytes. Am. J. Physiol. 264:1993;L116-L123.
27. Zhang F., Sowers J.R., Ram J.L., Standley P.R., Peuler J.D. Effects of proglitazone on calcium channels in vascular smooth muscle. Hypertension. 24:1994;170-175.