-
2
-
-
0032521274
-
Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma
-
Kline JN, Waldschmidt TJ, Businga TR et al. Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma. J Immunol 1998; 160:2555-9.
-
(1998)
J Immunol
, vol.160
, pp. 2555-2559
-
-
Kline, J.N.1
Waldschmidt, T.J.2
Businga, T.R.3
-
3
-
-
0036789431
-
Modulation of murine allergic rhinosinusitis by CpG oligodeoxynucleotides
-
Hussain I, Jain VV, Kitagaki K, Businga TR, O'Shaughnessy P, Kline JN. Modulation of murine allergic rhinosinusitis by CpG oligodeoxynucleotides. Laryngoscope 2002; 112:1819-26.
-
(2002)
Laryngoscope
, vol.112
, pp. 1819-1826
-
-
Hussain, I.1
Jain, V.V.2
Kitagaki, K.3
Businga, T.R.4
O'Shaughnessy, P.5
Kline, J.N.6
-
4
-
-
0036912223
-
CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma
-
Jain VV, Kitagaki K, Businga T et al. CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma. J Allergy Clin Immunol 2002; 110:867-72.
-
(2002)
J Allergy Clin Immunol
, vol.110
, pp. 867-872
-
-
Jain, V.V.1
Kitagaki, K.2
Businga, T.3
-
5
-
-
0028956439
-
Is allergen immunotherapy effective in asthma? A meta-analysis of randomized controlled trials
-
Abramson MJ, Puy RM, Weiner JM. Is allergen immunotherapy effective in asthma? a meta-analysis of randomized controlled trials. Am J Respir Crit Care Med 1995; 151:969-74.
-
(1995)
Am J Respir Crit Care Med
, vol.151
, pp. 969-974
-
-
Abramson, M.J.1
Puy, R.M.2
Weiner, J.M.3
-
7
-
-
0029932729
-
Lymphocyte activation by CpG dinucleotide motifs in prokaryotic DNA
-
Krieg AM. Lymphocyte activation by CpG dinucleotide motifs in prokaryotic DNA. Trends Microbiol 1996; 4:73-6.
-
(1996)
Trends Microbiol
, vol.4
, pp. 73-76
-
-
Krieg, A.M.1
-
8
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408:740-5.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
9
-
-
0036093704
-
A role for Toll in autoimmunity
-
Krieg AM. A role for Toll in autoimmunity. Nat Immunol 2002; 3:423-4.
-
(2002)
Nat Immunol
, vol.3
, pp. 423-424
-
-
Krieg, A.M.1
-
10
-
-
0035477969
-
Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells
-
Takeshita F, Leifer CA, Gursel I et al. Cutting edge: role of Toll-like receptor 9 in CpG DNA-induced activation of human cells. J Immunol 2001; 167:3555-8.
-
(2001)
J Immunol
, vol.167
, pp. 3555-3558
-
-
Takeshita, F.1
Leifer, C.A.2
Gursel, I.3
-
12
-
-
0029266795
-
Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice
-
Brusselle G, Kips J, Joos G, Bluethmann H, Pauwels R. Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice. Am J Respir Cell Mol Biol 1995; 12:254-9.
-
(1995)
Am J Respir Cell Mol Biol
, vol.12
, pp. 254-259
-
-
Brusselle, G.1
Kips, J.2
Joos, G.3
Bluethmann, H.4
Pauwels, R.5
-
13
-
-
0030028768
-
Interleukin 5 deficiency abolishes eosinophilia, airway hyperreactivity and lung damage in a mouse asthma model
-
Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. Interleukin 5 deficiency abolishes eosinophilia, airway hyperreactivity and lung damage in a mouse asthma model. J Exp Med 1996; 183:195-201.
-
(1996)
J Exp Med
, vol.183
, pp. 195-201
-
-
Foster, P.S.1
Hogan, S.P.2
Ramsay, A.J.3
Matthaei, K.I.4
Young, I.G.5
-
14
-
-
0029969336
-
Effect of antigen provocation of IL-5 transgenic mice on eosinophil mobilization and bronchial hyperresponsiveness
-
Lefort J, Bachelet CM, Leduc D, Vargaftig BB. Effect of antigen provocation of IL-5 transgenic mice on eosinophil mobilization and bronchial hyperresponsiveness. J Allergy Clin Immunol 1996; 97:788-99.
-
(1996)
J Allergy Clin Immunol
, vol.97
, pp. 788-799
-
-
Lefort, J.1
Bachelet, C.M.2
Leduc, D.3
Vargaftig, B.B.4
-
15
-
-
16044371529
-
Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity
-
Rankin JA, Picarella DE, Geba GP et al. Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc Natl Acad Sci USA 1996; 93:7821-5.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7821-7825
-
-
Rankin, J.A.1
Picarella, D.E.2
Geba, G.P.3
-
16
-
-
0030068235
-
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity
-
Corry DB, Folkesson HG, Warnock ML et al. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med 1996; 183: 109-17.
-
(1996)
J Exp Med
, vol.183
, pp. 109-117
-
-
Corry, D.B.1
Folkesson, H.G.2
Warnock, M.L.3
-
17
-
-
0029335074
-
Interleukin-4 is required for the induction of lung Th2 mucosal immunity
-
Coyle AJ, Le Gros G, Bertrand C et al. Interleukin-4 is required for the induction of lung Th2 mucosal immunity. Am J Respir Cell Mol Biol 1995; 13:54-9.
-
(1995)
Am J Respir Cell Mol Biol
, vol.13
, pp. 54-59
-
-
Coyle, A.J.1
Le Gros, G.2
Bertrand, C.3
-
18
-
-
0000965148
-
TRFK-5 reverses established airway eosinophilia but not established hyperresponsiveness in a murine model of chronic asthma
-
Mathur M, Herrmann K, Li X et al. TRFK-5 reverses established airway eosinophilia but not established hyperresponsiveness in a murine model of chronic asthma. Am J Respir Crit Care Med 1999; 159:580-7.
-
(1999)
Am J Respir Crit Care Med
, vol.159
, pp. 580-587
-
-
Mathur, M.1
Herrmann, K.2
Li, X.3
-
19
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response
-
Leckie MJ, ten Brinke A, Khan J et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response. Lancet 2000; 356:2144-8.
-
(2000)
Lancet
, vol.356
, pp. 2144-2148
-
-
Leckie, M.J.1
Ten Brinke, A.2
Khan, J.3
-
20
-
-
0033429176
-
CpG oligodeoxynucleotides do not require Th1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma
-
Kline JN, Krieg AM, Waldschmidt TJ, Ballas ZK, Jain V, Businga TR. CpG oligodeoxynucleotides do not require Th1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma. J Allergy Clin Immunol 1999; 104: 1258-64.
-
(1999)
J Allergy Clin Immunol
, vol.104
, pp. 1258-1264
-
-
Kline, J.N.1
Krieg, A.M.2
Waldschmidt, T.J.3
Ballas, Z.K.4
Jain, V.5
Businga, T.R.6
-
21
-
-
0032534602
-
Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice
-
Broide D, Schwarze J, Tighe H et al. Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J Immunol 1998; 161:7054-62.
-
(1998)
J Immunol
, vol.161
, pp. 7054-7062
-
-
Broide, D.1
Schwarze, J.2
Tighe, H.3
-
22
-
-
0033563211
-
Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides
-
Sur S, Wild JS, Choudhury BK, Sur N, Alam R, Klinman DM. Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides. J Immunol 1999; 162:6284-93.
-
(1999)
J Immunol
, vol.162
, pp. 6284-6293
-
-
Sur, S.1
Wild, J.S.2
Choudhury, B.K.3
Sur, N.4
Alam, R.5
Klinman, D.M.6
-
23
-
-
0032545213
-
Interleukin-13: Central mediator of allergic asthma
-
Wills-Karp M, Luyimbazi J, Xu X et al. Interleukin-13: central mediator of allergic asthma. Science 1998; 282:2258-61.
-
(1998)
Science
, vol.282
, pp. 2258-2261
-
-
Wills-Karp, M.1
Luyimbazi, J.2
Xu, X.3
-
24
-
-
0036344597
-
Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma
-
Kuperman DA, Huang X, Koth LL et al. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med 2002; 8: 885-9.
-
(2002)
Nat Med
, vol.8
, pp. 885-889
-
-
Kuperman, D.A.1
Huang, X.2
Koth, L.L.3
-
25
-
-
0035888013
-
Critical role for IL-13 in the development of allergen-induced airway hyperreactivity
-
Walter DM, McIntire JJ, Berry G et al. Critical role for IL-13 in the development of allergen-induced airway hyperreactivity. J Immunol 2001; 167:4668-75.
-
(2001)
J Immunol
, vol.167
, pp. 4668-4675
-
-
Walter, D.M.1
McIntire, J.J.2
Berry, G.3
-
26
-
-
0032531571
-
IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1, cells
-
Cohn L, Tepper JS, Bottomly K. IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1, cells. J Immunol 1998; 161:3813-6.
-
(1998)
J Immunol
, vol.161
, pp. 3813-3816
-
-
Cohn, L.1
Tepper, J.S.2
Bottomly, K.3
-
27
-
-
0037215576
-
Differential regulation by glucocorticoid of interleukin-13-induced eosinophilia, hyperresponsiveness, and goblet cell hyperplasia in mouse airways
-
Kibe A, Inoue H, Fukuyama S et al. Differential regulation by glucocorticoid of interleukin-13-induced eosinophilia, hyperresponsiveness, and goblet cell hyperplasia in mouse airways. Am J Respir Crit Care Med 2003; 167:50-6.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 50-56
-
-
Kibe, A.1
Inoue, H.2
Fukuyama, S.3
-
28
-
-
0036884608
-
The role of IL-13 in established allergic airway disease
-
Taube C, Duez C, Cui ZH et al. The role of IL-13 in established allergic airway disease. J Immunol 2002; 169:6482-9.
-
(2002)
J Immunol
, vol.169
, pp. 6482-6489
-
-
Taube, C.1
Duez, C.2
Cui, Z.H.3
-
29
-
-
0034670048
-
CpG oligodeoxynucleotides can reverse Th2-associated allergic airway responses and alter the B7.1/B7.2 expression in a murine model of asthma
-
Serebrisky D, Teper AA, Huang CK et al. CpG oligodeoxynucleotides can reverse Th2-associated allergic airway responses and alter the B7.1/B7.2 expression in a murine model of asthma. J Immunol 2000; 165:5906-12.
-
(2000)
J Immunol
, vol.165
, pp. 5906-5912
-
-
Serebrisky, D.1
Teper, A.A.2
Huang, C.K.3
-
30
-
-
0036224842
-
Effects of post-inhalation treatment with interleukin-12 on airway hyper-reactivity, eosinophilia and interleukin-18 receptor expression in a mouse model of asthma
-
Kuribayashi K, Kodama T, Okamura H, Sugita M, Matsuyama T. Effects of post-inhalation treatment with interleukin-12 on airway hyper-reactivity, eosinophilia and interleukin-18 receptor expression in a mouse model of asthma. Clin Exp Allergy 2002; 32:641-9.
-
(2002)
Clin Exp Allergy
, vol.32
, pp. 641-649
-
-
Kuribayashi, K.1
Kodama, T.2
Okamura, H.3
Sugita, M.4
Matsuyama, T.5
-
31
-
-
0028824039
-
IL-12 deaths: Explanation and a puzzle
-
Cohen J. IL-12 deaths: explanation and a puzzle. Science 1995; 270:908.
-
(1995)
Science
, vol.270
, pp. 908
-
-
Cohen, J.1
-
32
-
-
6644223789
-
Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response
-
Bryan SA, O'Connor BJ, Matti S et al. Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 2000; 356:2149-53.
-
(2000)
Lancet
, vol.356
, pp. 2149-2153
-
-
Bryan, S.A.1
O'Connor, B.J.2
Matti, S.3
-
33
-
-
0033429176
-
CpG oligodeoxynucleotides do not require TH1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma
-
Kline JN, Krieg AM, Waldschmidt TJ, Ballas ZK, Jain V, Businga TR. CpG oligodeoxynucleotides do not require TH1 cytokines to prevent eosinophilic airway inflammation in a murine model of asthma. J Allergy Clin Immunol 1999; 104:1258-64.
-
(1999)
J Allergy Clin Immunol
, vol.104
, pp. 1258-1264
-
-
Kline, J.N.1
Krieg, A.M.2
Waldschmidt, T.J.3
Ballas, Z.K.4
Jain, V.5
Businga, T.R.6
-
34
-
-
0036844343
-
Immunomodulatory effects of CpG oligodeoxynucleotides on established Th2 responses
-
Kitagaki K, Jain V, Businga T, Hussain I, Kline J. Immunomodulatory effects of CpG oligodeoxynucleotides on established Th2 responses. Clin Diag Lab Immunol 2002; 9:1260-9.
-
(2002)
Clin Diag Lab Immunol
, vol.9
, pp. 1260-1269
-
-
Kitagaki, K.1
Jain, V.2
Businga, T.3
Hussain, I.4
Kline, J.5
-
35
-
-
0032521274
-
Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma
-
Kline JN, Waldschmidt TJ, Businga TR et al. Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma. J Immunol 1998; 160:2555-9.
-
(1998)
J Immunol
, vol.160
, pp. 2555-2559
-
-
Kline, J.N.1
Waldschmidt, T.J.2
Businga, T.R.3
-
36
-
-
0034040529
-
Regulation of T-helper type 2 cell and airway eosinophilia by transmucosal coadministration of antigen and oligodeoxynucleotides containing CpG motifs
-
Shirota H, Sano K, Kikuchi T, Tamura G, Shirato K. Regulation of T-helper type 2 cell and airway eosinophilia by transmucosal coadministration of antigen and oligodeoxynucleotides containing CpG motifs. Am J Respir Cell Mol Biol 2000; 22:176-82.
-
(2000)
Am J Respir Cell Mol Biol
, vol.22
, pp. 176-182
-
-
Shirota, H.1
Sano, K.2
Kikuchi, T.3
Tamura, G.4
Shirato, K.5
-
37
-
-
0034090116
-
Regulation of murine airway eosinophilia and Th2 cells by antigen-conjugated CpG oligodeoxynucleotides as a novel antigen-specific immuno-modulator
-
Shirota H, Sano K, Kikuchi T, Tamura G, Shirato K. Regulation of murine airway eosinophilia and Th2 cells by antigen-conjugated CpG oligodeoxynucleotides as a novel antigen-specific immuno-modulator. J Immunol 2000; 164:5575-82.
-
(2000)
J Immunol
, vol.164
, pp. 5575-5582
-
-
Shirota, H.1
Sano, K.2
Kikuchi, T.3
Tamura, G.4
Shirato, K.5
-
38
-
-
0031863964
-
Long-lasting sensitization to food during the first two years precedes allergic airway disease
-
The MAS Study Group, Germany
-
Kulig M, Bergmann R, Tacke U, Wahn U, Guggenmoos-Holzmann I. Long-lasting sensitization to food during the first two years precedes allergic airway disease. The MAS Study Group, Germany. Pediatr Allergy Immunol 1998; 9:61-7.
-
(1998)
Pediatr Allergy Immunol
, vol.9
, pp. 61-67
-
-
Kulig, M.1
Bergmann, R.2
Tacke, U.3
Wahn, U.4
Guggenmoos-Holzmann, I.5
-
39
-
-
0030139443
-
Lung inflammation and epithelial changes in a murine model of atopic asthma
-
Blyth DI, Pedrick MS, Savage TJ, Hessel EM, Fattah D. Lung inflammation and epithelial changes in a murine model of atopic asthma. Am J Respir Cell Mol Biol 1996; 14: 425-38.
-
(1996)
Am J Respir Cell Mol Biol
, vol.14
, pp. 425-438
-
-
Blyth, D.I.1
Pedrick, M.S.2
Savage, T.J.3
Hessel, E.M.4
Fattah, D.5
-
40
-
-
0035084068
-
Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice
-
Tomkinson A, Cieslewicz G, Duez C, Larson KA, Lee JJ, Gelfand EW. Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice. Am J Respir Crit Care Med 2001; 163:721-30.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 721-730
-
-
Tomkinson, A.1
Cieslewicz, G.2
Duez, C.3
Larson, K.A.4
Lee, J.J.5
Gelfand, E.W.6
-
41
-
-
0036126748
-
Amb a 1-linked CpG oligodeoxynucleotides reverse established airway hyperresponsiveness in a murine model of asthma
-
Santeliz JV, Van Nest G, Traquina P, Larsen E, Wills-Karp M. Amb a 1-linked CpG oligodeoxynucleotides reverse established airway hyperresponsiveness in a murine model of asthma. J Allergy Clin Immunol 2002; 109:455-62.
-
(2002)
J Allergy Clin Immunol
, vol.109
, pp. 455-462
-
-
Santeliz, J.V.1
Van Nest, G.2
Traquina, P.3
Larsen, E.4
Wills-Karp, M.5
-
42
-
-
0027181170
-
The lack of distensibility of asthmatic airways
-
Wilson JW, Li X, Pain MC. The lack of distensibility of asthmatic airways. Am Rev Respir Dis 1993; 148:806-9.
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 806-809
-
-
Wilson, J.W.1
Li, X.2
Pain, M.C.3
-
44
-
-
0031978792
-
Dexamethasone activates expression of the PDGF-alpha receptor and induces lung fibroblast proliferation
-
Warshamana GS, Martinez S, Lasky JA, Corti M, Brody AR. Dexamethasone activates expression of the PDGF-alpha receptor and induces lung fibroblast proliferation. Am J Physiol 1998; 274:L499-507.
-
(1998)
Am J Physiol
, vol.274
-
-
Warshamana, G.S.1
Martinez, S.2
Lasky, J.A.3
Corti, M.4
Brody, A.R.5
-
45
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu Z, Homer RJ, Wang Z et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999; 103:779-88.
-
(1999)
J Clin Invest
, vol.103
, pp. 779-788
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
-
46
-
-
0035881129
-
Role of CD4(+) CD25(+) regulatory T cells in T helper 2 cell-mediated allergic inflammation in the airways
-
Suto A, Nakajima H, Kagami SI, Suzuki K, Saito Y, Iwamoto I. Role of CD4(+) CD25(+) regulatory T cells in T helper 2 cell-mediated allergic inflammation in the airways. Am J Respir Crit Care Med 2001; 164:680-7.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 680-687
-
-
Suto, A.1
Nakajima, H.2
Kagami, S.I.3
Suzuki, K.4
Saito, Y.5
Iwamoto, I.6
-
47
-
-
0034327264
-
T regulatory cells 1 inhibit a Th2-specific response in vivo
-
Cottrez F, Hurst SD, Coffman RL, Groux H. T regulatory cells 1 inhibit a Th2-specific response in vivo. J Immunol 2000; 165: 4848-53.
-
(2000)
J Immunol
, vol.165
, pp. 4848-4853
-
-
Cottrez, F.1
Hurst, S.D.2
Coffman, R.L.3
Groux, H.4
-
48
-
-
0036476320
-
From a to Z on CpG
-
Krieg AM. From A to Z on CpG. Trends Immunol 2002; 23:64-5.
-
(2002)
Trends Immunol
, vol.23
, pp. 64-65
-
-
Krieg, A.M.1
|