Dynamic Control of Neuronal Morphogenesis by Rho Signaling

Journal of Biochemistry

Volumn 134, Issue 3, 2003, Pages 315-319

  Bito, Haruhiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Actin; Axon outgrowth; Cerebellar granule neurons; mDia1; ROCK

Indexed keywords

GUANOSINE TRIPHOSPHATASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE;

CELL POLARITY; CELL ULTRASTRUCTURE; CONTROL SYSTEM; CYTOSKELETON; ENZYME ACTIVITY; HUMAN; METAMORPHOSIS; MICROTUBULE; MOLECULAR DYNAMICS; MOLECULAR MODEL; MORPHOGENESIS; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NERVE FIBER GROWTH; NEURITE; NONHUMAN; PERIKARYON; POLARIZATION; SHORT SURVEY; SIGNAL TRANSDUCTION;

AXONS; CENTRAL NERVOUS SYSTEM; CYTOSKELETON; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; MORPHOGENESIS; NEURONS; PROTEIN-SERINE-THREONINE KINASES; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 0142026443     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/jb/mvg147     Document Type: Short Survey

References (63)

1. Goodman, C.S. and Shatz, C.J. (1993) Developmental mechanisms that generate precise patterns of neuronal connectivity. Cell Suppl. 72, 77-98
2. da Silva, J.S. and Dotti, C.G. (2002) Breaking the neuronal sphere: regulation of the actin cytoskeleton in neuritogenesis. Nat. Rev. Neurosci. 3, 694-704
3. Dingwell, K.S., Holt, C.E., and Harris, W.A. (2000) The multiple decisions made by growth cones of RGCs as they navigate from the retina to the tectum in Xenopus embryos. J. Neurobiol. 44, 246-259
4. Culotti, J.G. and Kolodkin, A.L. (1996) Functions of netrins and semaphorins in axon guidance. Curr. Opin. Neurobiol. 6, 81-88
5. Tessier-Lavigne, M., and Goodman, C.S. (1996) The molecular biology of axon guidance. Science 274, 1123-1133
6. Van Vactor, D. and Flanagan, J.G. (1999) The middle and the end: slit brings guidance and branching together in axon pathway selection. Neuron 22, 649-652
7. Huang, E.J. and Reichardt, L.F. (2001) Neurotrophins: roles in neuronal development and function. Ann. Rev. Neurosci. 24, 677-736
8. Liu, B.P. and Strittmatter, S.M. (2001) Semaphorin-mediated axonal guidance via Rho-related G proteins. Curr. Opin. Cell Biol. 13, 619-626
9. Tanaka, E. and Sabry, J. (1995) Making the connection: cytoskeletal rearrangements during growth cone guidance. Cell 83, 171-176
10. Luo, L. (2002) Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity. Annu. Rev. Cell. Dev. Biol. 18, 601-635
11. Narumiya, S., Ishizaki, T., and Watanabe, N. (1997) Rho effectors and reorganization of actin cytoskeleton. FEBS Lett. 410, 68-72
12. Gallo, G. and Letourneau, P.C. (1998) Axon guidance: GTPases help axons reach their targets. Curr. Biol. 8, R80-R82
13. Luo, L. (2000) Rho GTPases in neuronal morphogenesis. Nat. Rev. Neurosci. 1, 173-180
14. Dickson, B.J. (2001) Rho GTPases in growth cone guidance. Curr. Opin. Neurobiol. 11, 103-110
15. Nikolic, M. (2002) The role of Rho GTPases and associated kinases in regulating neurite outgrowth. Int. J. Biochem. Cell Biol. 34, 731-745
16. Etienne-Manneville, S., and Hall, A. (2002) Rho GTPases in cell biology. Nature 420, 629-635
17. Sebok, A., Nusser, N., Debreceni, B., Guo, Z., Santos, M.F., Szeberenyi, J., and Tigyi, G. (1999) Different roles for RhoA during neurite initiation, elongation, and regeneration in PC12 cells. J. Neurochem. 73, 949-960
18. Bashaw, G.J., Hu, H., Nobes, C.D., and Goodman, C.S. (2001) A novel Dbl family RhoGEF promotes Rho-dependent axon attraction to the central nervous system midline in Drosophila and overcomes Robo repulsion. J. Cell Biol. 155, 1117-1122
19. Billuart, P., Bienvenu, T., Ronce, N., des Portes, V., Vinet, M.C., Zemni, R., Roest, Crollius, H., Carrie, A., Fauchereau, F., Cherry, M., Briault, S., Hamel, B., Fryns, J.P., Beldjord, C., Kahn, A., Moraine, C., and Chelly, J. (1998) Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation. Nature 392, 923-926
20. Kutsche, K., Yntema, H., Brandt, A., Jantke, I., Nothwang, H.G., Orth, U., Boavida, M.G., David, D., Chelly, J., Fryns, J.P., Moraine, C., Ropers, H.H., Hamel, B.C., van Bokhoven, H., and Gal, A. (2000) Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation. Nat. Genet. 26, 247-250
21. Allen, K.M., Gleeson, J.G., Bagrodia, S., Partington, M.W., MacMillan, J.C., Cerione, R.A., Mulley, J.C., and Walsh, C.A. (1998) PAK3 mutation in nonsyndromic X-linked mental retardation. Nat. Genet. 20, 25-30
22. Frangiskakis, J.M., Ewart, A.K., Morris, C.A., Mervis, C.B., Bertrand, J., Robinson, B.F., Klein, B.P., Ensing, G.J., Everett, L.A., Green, E.D., Proschel, C., Gutowski, N.J., Noble, M., Atkinson, D.L., Odelberg, S.J., and Keating, M.T. (1996) LIM-kinase1 hemizygosity implicated in impaired visuospatial constructive cognition. Cell 86, 59-69
23. Tassabehji, M., Metcalfe, K., Fergusson, W.D., Carette, M.J., Dore, J.K., Donnai, D., Read, A.P., Proschel, C., Gutowski, N.J., Mao, X., and Sheer, D. (1996) LIM-kinase deleted in Williams syndrome. Nature Genet 13, 272-273
24. Schenck, A., Bardoni, B., Langmann, C., Harden, N., Mandel, J.L., and Giangrande, A. (2003) CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein. Neuron 38, 887-898
25. Bito, H., Furuyashiki, T., Ishihara, H., Shibasaki, Y., Ohashi, K., Mizuno, K., Maekawa, M., Ishizaki, T., and Narumiya, S. (2000) A critical role for a Rho-associated kinase, p160ROCK, in determining axon outgrowth in mammalian CNS neurons. Neuron 26, 431-441
26. Arakawa, Y., Bito, H., Furuyashiki, T., Tsuji, T., Takemoto-Kimura, S., Kimura, K., Nozaki, K., Hashimoto, N., and Narumiya, S. (2003) Control of axon elongation via an SDF-1alpha/Rho/mDia pathway in cultured cerebellar granule neurons. J. Cell Biol. 161, 381-391
27. Fournier, A.E., Takizawa, B.T., and Strittmatter, S.M. (2003) Rho kinase inhibition enhances axonal regeneration in the injured CNS. J. Neurosci. 23, 1416-1423
28. Yuan, X.B., Jin, M., Xu, X., Song, Y.Q., Wu, C.P., Poo, M.M., and Duan, S. (2003) Signalling and crosstalk of Rho GTPases in mediating axon guidance. Nat. Cell Biol. 5, 38-45
29. Threadgill, R., Bobb, K., and Ghosh, A. (1997) Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42. Neuron 19, 625-634
30. Kimura, K., Ito, M., Amano, M., Chihara, K., Fukata, Y., Nakafuku, M., Yamamori, B., Feng, J., Nakano, T., Okawa, K., Iwamatsu, A., and Kaibuchi, K. (1996) Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science. 273, 245-248
31. Uehata, M., Ishizaki, T., Satoh, H., Ono, T., Kawahara, T., Morishita, T., Tamakawa, H., Yamagami, K., Inui, J., Maekawa, M., and Narumiya S. (1997) Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389, 990-994
32. Dontchev, V.D. and Letourneau, P.C. (2002) Nerve growth factor and semaphorin 3A signaling pathways interact in regulating sensory neuronal growth cone motility. J. Neurosci. 22, 6659-6669
33. Watanabe, N., Madaule, P., Reid, T., Ishizaki, T., Watanabe, G., Kakizuka, A., Saito, Y., Nakao, K., Jockusch, B.M., and Narumiya, S. (1997) p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. EMBO J. 16, 3044-3056
34. Watanabe, N., Kato, T., Fujita, A., Ishizaki, T., and Narumiya, S. (1999) Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nat. Cell Biol. 1, 136-143
35. Tominaga, T., Meng, W., Togashi, K., Urano, H., Alberts, A.S., and Tominaga M. (2002, 2003) The Rho GTPase effector protein, mDia, inhibits the DNA binding ability of the transcription factor Pax6 and changes the pattern of neurite extension in cerebellar granule cells through its binding to Pax6. J. Biol. Chem. 277, 47686-47691; Erratum in: J. Biol. Chem. 278, 17580
36. Tominaga, T., Meng, W., Togashi, K., Urano, H., Alberts, A.S., and Tominaga M. (2002, 2003) The Rho GTPase effector protein, mDia, inhibits the DNA binding ability of the transcription factor Pax6 and changes the pattern of neurite extension in cerebellar granule cells through its binding to Pax6. J. Biol. Chem. 277, 47686-47691; Erratum in: J. Biol. Chem. 278, 17580
37. Tsuji, T., Ishizaki, T., Okamoto, M., Higashida, C., Kimura, K., Furuyashiki, T., Arakawa, Y., Birge, R.B., Nakamoto, T., Hirai, H., and Narumiya S. (2002) ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts. J. Cell Biol. 157, 819-830
38. Sahai, E. and Marshall, C.J. (2002) ROCK and Dia have opposing effects on adherens junctions downstream of Rho. Nat. Cell Biol. 4, 408-415
39. Kimura, K., Tsuji, T., Takada, Y., Miki, T., and Narumiya, S. (2000) Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation. J. Biol. Chem. 275, 17233-17236
40. Alberts, A.S. (2002) Diaphanous-related Formin homology proteins. Curr Biol. 12, R796
41. Castrillon, D.H. and Wasserman, S.A. (1994) Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. Development 120, 3367-3377
42. Kohno, H., Tanaka, K., Mino, A., Umikawa, M., Imamura, H., Fujiwara, T., Fujita, Y., Hotta, K., Qadota, H., Watanabe, T., Ohya, Y., and Takai Y. (1996) Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae. EMBO J. 15, 6060-6068
43. Chang, F., Drubin, D., and Nurse, P. (1997) cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin. J. Cell Biol. 137, 169-182
44. Evangelista, M., Blundell, K., Longtine, M.S., Chow, C.J., Adames, N., Pringle, J.R., Peter, M., and Boone, C. (1997) Bnilp, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis. Science 276, 118-122
45. Swan, K.A., Severson, A.F., Carter, J.C., Martin, P.R., Schnabel, H., Schnabel, R., and Bowerman, B. (1998) cyk-1: a C. elegans FH gene required for a late step in embryonic cytokinesis. J. Cell Sci. 111, 2017-2027
46. Ozaki-Kuroda, K., Yamamoto, Y., Nohara, H., Kinoshita, M., Fujiwara, T., Irie, K., and Takai, Y. (2001) Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae. Mol. Cell. Biol. 21, 827-839
47. Narumiya, S. and Mabuchi, I. (2002) Cell biology: spinning actin to divide. Nature 419, 27-28
48. Sagot, I., Klee, S.K., and Pellman, D. (2002) Yeast formins regulate cell polarity by controlling the assembly of actin cables. Nat. Cell Biol. 4, 42-50
49. Evangelista, M., Pruyne, D., Amberg, D.C., Boone, C., and Bretscher A. (2002) Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast. Nat. Cell Biol. 4, 32-41
50. Pruyne, D., Evangelista, M., Yang, C., Bi, E., Zigmond, S., Bretscher, A., and Boone, C. (2002) Role of formins in actin assembly: nucleation and barbed-end association. Science 297, 612-615
51. Sagot, I., Rodal, A.A., Moseley, J., Goode, B.L., and Pellman, D. (2002) An actin nucleation mechanism mediated by Bni1 and profilin. Nat. Cell Biol. 4, 626-631
52. Copeland, J.W. and Treisman, R. (2002) The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization. Mol. Biol. Cell. 13, 4088-4099
53. Kovar, D.R., Kuhn, J.R., Tichy, A.L., and Pollard, T.D. (2003) The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin. J. Cell Biol. 161, 875-887
54. Li, F. and Higgs, H.N. (2003) The mouse formin mDia1 is a potent actin nucleation factor regulated by autoinhibition. Curr. Biol. 13, 1335-1340
55. Evangelista, M., Zigmond, S., and Boone, C. (2003) Formins: signaling effectors for assembly and polarization of actin filaments. J. Cell Sci. 116, 2603-2611
56. Bretscher, A. (2003) Polarized growth and organelle segregation in yeast: the tracks, motors, and receptors. J. Cell Biol. 160, 811-816
57. Gundersen, G.G. and Bretscher, A. (2003) Cell biology. Microtubule asymmetry. Science 300, 2040-2041
58. Rodriguez, O.C., Schaefer, A.W., Mandato, C.A., Forscher, P., Bement, W.M., and Waterman-Storer, C.M. (2003) Conserved microtubule-actin interactions in cell movement and morphogenesis. Nat. Cell Biol. 5, 599-609
59. Ishizaki, T., Morishima, Y., Okamoto, M., Furuyashiki, T., Kato, T., and Narumiya, S. (2001) Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1. Nat. Cell Biol. 3, 8-14
60. Palazzo, A.F., Cook, T.A., Alberts, A.S., and Gundersen, G.G. (2001) mDia mediates Rho-regulated formation and orientation of stable microtubules. Nat. Cell Biol. 3, 723-729
61. Dent, E.W. and Kalil, K. (2001) Axon branching requires interactions between dynamic microtubules and actin filaments. J. Neurosci. 21, 9757-9769
62. Schaefer, A.W., Kabir, N., and Forscher, P. (2002) Filopodia and actin arcs guide the assembly and transport of two populations of microtubules with unique dynamic parameters in neuronal growth cones. J. Cell Biol. 158, 139-152
63. Vignjevic, D., Yarar, D., Welch, M.D., Peloquin, J., Svitkina, T., and Borisy, G.G. (2003) Formation of filopodia-like bundles in vitro from a dendritic network. J. Cell Biol. 160, 951-962