-
1
-
-
0031886680
-
Self-administered topical 5% imiquimod cream for external anogenital warts
-
Edwards L, Ferenczy A, Eron L, et al. Self-administered topical 5% imiquimod cream for external anogenital warts. Arch Dermatol. 1998;134:25-30.
-
(1998)
Arch Dermatol
, vol.134
, pp. 25-30
-
-
Edwards, L.1
Ferenczy, A.2
Eron, L.3
-
2
-
-
0034145718
-
Topical imiquimod for recalcitrant facial flat warts
-
Schwab R, Elston D. Topical imiquimod for recalcitrant facial flat warts. Cutis. 2000;65:160-163.
-
(2000)
Cutis
, vol.65
, pp. 160-163
-
-
Schwab, R.1
Elston, D.2
-
3
-
-
0033747683
-
Self-administered topical 5% imiquimod for the treatment of common warts and molluscum contaglosum
-
Hengge U, Esser S, Schultewolter T, et al. Self-administered topical 5% imiquimod for the treatment of common warts and molluscum contaglosum. Br J Dermatol. 2000;143:1026-1031.
-
(2000)
Br J Dermatol
, vol.143
, pp. 1026-1031
-
-
Hengge, U.1
Esser, S.2
Schultewolter, T.3
-
4
-
-
0035102498
-
Imiquimod 5% cream in the treatment of Bowen's disease
-
Mackenzie-Wood A, Kossard S, de Launey J, Wilkinson B, Owens ML. Imiquimod 5% cream in the treatment of Bowen's disease. J Am Acad Dermatol 2001;44:462-470.
-
(2001)
J Am Acad Dermatol
, vol.44
, pp. 462-470
-
-
Mackenzie-Wood, A.1
Kossard, S.2
De Launey, J.3
Wilkinson, B.4
Owens, M.L.5
-
5
-
-
0033743997
-
Imiquimod: A novel treatment for lentigo maligna
-
Ahmed I, Berth-Jones J. Imiquimod: a novel treatment for lentigo maligna. Br J Dermatol. 2000;143:843-845.
-
(2000)
Br J Dermatol
, vol.143
, pp. 843-845
-
-
Ahmed, I.1
Berth-Jones, J.2
-
6
-
-
0036786777
-
Treatment of primary limited cutaneous extramammary Paget's disease with topical imiquimod monotherapy: Two case reports
-
Zampogna J, Flowers F, Roth W, Hassenein A. Treatment of primary limited cutaneous extramammary Paget's disease with topical imiquimod monotherapy: two case reports. J Am Acad Dermatol. 2002;47:S229-S235.
-
(2002)
J Am Acad Dermatol
, vol.47
-
-
Zampogna, J.1
Flowers, F.2
Roth, W.3
Hassenein, A.4
-
7
-
-
0036718001
-
Treatment of stage IA cutaneous T-cell lymphoma with topical application of the immune response modifier imiquimod
-
Suchin K, Junkins-Hopkins J, Rook A. Treatment of stage IA cutaneous T-cell lymphoma with topical application of the immune response modifier imiquimod. Arch Dermatol. 2002;138:1137-1139.
-
(2002)
Arch Dermatol
, vol.138
, pp. 1137-1139
-
-
Suchin, K.1
Junkins-Hopkins, J.2
Rook, A.3
-
8
-
-
0036845121
-
A randomized, double-blind, vehicle-controlled study to assess 5% imiquimod cream for the treatment of multiple actinic keratoses
-
Stockfleth E, Meyer T, Benninghoff B, et al. A randomized, double-blind, vehicle-controlled study to assess 5% imiquimod cream for the treatment of multiple actinic keratoses. Arch Dermatol. 2002;138:1498-1502.
-
(2002)
Arch Dermatol
, vol.138
, pp. 1498-1502
-
-
Stockfleth, E.1
Meyer, T.2
Benninghoff, B.3
-
9
-
-
0035028717
-
Imiquimod 5% cream in the treatment of superficial basal cell carcinomas: Results of a multicenter 6-week dose-response trial
-
Marks R, Gebauer K, Shumack S, et al. Imiquimod 5% cream in the treatment of superficial basal cell carcinomas: results of a multicenter 6-week dose-response trial. J Am Acad Dermatol 2001;44:807-813.
-
(2001)
J Am Acad Dermatol
, vol.44
, pp. 807-813
-
-
Marks, R.1
Gebauer, K.2
Shumack, S.3
-
10
-
-
0141926501
-
Mechanisms underlying imiquimod-induced regression of basal cell carcinoma in vivo
-
Urosevic M, Maier T, Benninghoff B, Slade H, Burg G, Dummer R. Mechanisms underlying imiquimod-induced regression of basal cell carcinoma in vivo. Arch Dermatol. 2003;139:1325-1332.
-
(2003)
Arch Dermatol
, vol.139
, pp. 1325-1332
-
-
Urosevic, M.1
Maier, T.2
Benninghoff, B.3
Slade, H.4
Burg, G.5
Dummer, R.6
-
11
-
-
0027958391
-
Cytokine induction in mice by the immunomodulator imiquimod
-
Reiter M, Testerman T, Miller R, Weeks C, Tomal M. Cytokine induction in mice by the immunomodulator imiquimod. J Leukocyte Biol. 1994;55:234-240.
-
(1994)
J Leukocyte Biol
, vol.55
, pp. 234-240
-
-
Reiter, M.1
Testerman, T.2
Miller, R.3
Weeks, C.4
Tomal, M.5
-
12
-
-
0028070090
-
Induction of interferon and other cytokines by imiquimod and its hydroxylated metabolite R-842 in human blood cells in vitro
-
Weeks C, Gibson S. Induction of interferon and other cytokines by imiquimod and its hydroxylated metabolite R-842 in human blood cells in vitro. J Interferon Res. 1994;14:81-85.
-
(1994)
J Interferon Res
, vol.14
, pp. 81-85
-
-
Weeks, C.1
Gibson, S.2
-
13
-
-
0029099053
-
Cytokine induction by the immunomodulators imiquimod and S-27609
-
Testerman T, Gerster J, Imbertson L, et al. Cytokine induction by the immunomodulators imiquimod and S-27609. J Leukocyte Biol. 1995;58:365-372.
-
(1995)
J Leukocyte Biol
, vol.58
, pp. 365-372
-
-
Testerman, T.1
Gerster, J.2
Imbertson, L.3
-
14
-
-
0034120295
-
Imiquimod, a topical immune response modifier, induces migration of Langerhans cells
-
Suzuki H, Wang B, Shivji GM, et al. Imiquimod, a topical immune response modifier, induces migration of Langerhans cells. J Invest Dermatol. 2000;114:135-141.
-
(2000)
J Invest Dermatol
, vol.114
, pp. 135-141
-
-
Suzuki, H.1
Wang, B.2
Shivji, G.M.3
-
15
-
-
0031900829
-
Cytokine induction in hairless mouse and rat skin after topical application of the immune response modifiers imiquimod and S-28463
-
Imbertson L, Beaurline J, Couture A, et al. Cytokine induction in hairless mouse and rat skin after topical application of the immune response modifiers imiquimod and S-28463. J Invest Dermatol. 1998;110:734-739.
-
(1998)
J Invest Dermatol
, vol.110
, pp. 734-739
-
-
Imbertson, L.1
Beaurline, J.2
Couture, A.3
-
16
-
-
0030595339
-
The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann J. The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 1996;86:973-983.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.5
-
17
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway C. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 1997;388:394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway, C.3
-
18
-
-
0037013830
-
Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets
-
Ito T, Amakawa R, Kalsho T, et al. Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets. J Exp Med. 2002;195:1507-1512.
-
(2002)
J Exp Med
, vol.195
, pp. 1507-1512
-
-
Ito, T.1
Amakawa, R.2
Kalsho, T.3
-
19
-
-
0036008014
-
Small antiviral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
Hemmi H, Kalsho T, Takeuchi O, et al. Small antiviral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 2002;3:196-200.
-
(2002)
Nat Immunol
, vol.3
, pp. 196-200
-
-
Hemmi, H.1
Kalsho, T.2
Takeuchi, O.3
-
20
-
-
0025774776
-
Drosophila Toll and IL-1 receptor
-
Gay N, Keith F. Drosophila Toll and IL-1 receptor. Nature. 1991;351:355-356.
-
(1991)
Nature
, vol.351
, pp. 355-356
-
-
Gay, N.1
Keith, F.2
-
21
-
-
0032133278
-
MyD88 Is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov R, Preston-Hurlburt P, Kopp E, et al. MyD88 Is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol Cell. 1998;2:253-258.
-
(1998)
Mol Cell
, vol.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
-
22
-
-
0033776154
-
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor
-
Burns K, Clatworthy J, Martin L, et al. Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor. Nat Cell Biol. 2000;2:346-351.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 346-351
-
-
Burns, K.1
Clatworthy, J.2
Martin, L.3
-
23
-
-
0033580466
-
The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signaling pathway
-
Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J-I, Cao Z, Matsumoto K. The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signaling pathway. Nature. 1999;398:252-256.
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya-Tsuji, J.1
Kishimoto, K.2
Hiyama, A.3
Inoue, J.-I.4
Cao, Z.5
Matsumoto, K.6
-
24
-
-
0033567388
-
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway
-
Kopp E, Medzhitov R, Carothers J, et al. ECSIT is an evolutionarily conserved intermediate in the Toll/ IL-1 signal transduction pathway. Genes Dev. 1999;13:2059-2071.
-
(1999)
Genes Dev
, vol.13
, pp. 2059-2071
-
-
Kopp, E.1
Medzhitov, R.2
Carothers, J.3
-
25
-
-
0034625170
-
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration
-
Xia Y, Makris C, Su B, et al. MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration. Proc Natl Acad Sci U S A. 2000;97:5243-5248.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5243-5248
-
-
Xia, Y.1
Makris, C.2
Su, B.3
-
26
-
-
0032583949
-
Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
-
Nakano H, Shindo M, Sakon S, et al. Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1. Proc Natl Acad Sci USA. 1998;95:3537-3542.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3537-3542
-
-
Nakano, H.1
Shindo, M.2
Sakon, S.3
-
27
-
-
0034175930
-
The IKK complex: An integrator of all signals that activate NF-κB?
-
Israel A. The IKK complex: an integrator of all signals that activate NF-κB? Trends Cell Biol 2000;10:129-133.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 129-133
-
-
Israel, A.1
-
28
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation
-
Yamaoka S, Courtois G, Bessia C, et al. Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation. Cell. 1998;93:1231-1240.
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
Courtois, G.2
Bessia, C.3
-
29
-
-
0030961008
-
Activation of the hematopoetic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor β, (TGF-β)-activated kinase (TAK1), a kinase mediator of TGF-β signal transduction
-
Wang W, Zhou G, Hu M, Yao Z, Tan T-H. Activation of the hematopoetic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor β, (TGF-β)-activated kinase (TAK1), a kinase mediator of TGF-β signal transduction. J Biol Chem. 1997;272:22771-22775.
-
(1997)
J Biol Chem
, vol.272
, pp. 22771-22775
-
-
Wang, W.1
Zhou, G.2
Hu, M.3
Yao, Z.4
Tan, T.-H.5
-
30
-
-
15844431960
-
A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3
-
Moriguchi T, Kuroyanagi N, Yamaguchi K, et al. A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3. J Biol Chem. 1996;271:13675-13679.
-
(1996)
J Biol Chem
, vol.271
, pp. 13675-13679
-
-
Moriguchi, T.1
Kuroyanagi, N.2
Yamaguchi, K.3
-
31
-
-
0030051528
-
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
-
Raingeaud J, Whitmarsh A, Barrett T, Derijard B, Davis R. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol. 1996;16:1247-1255.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1247-1255
-
-
Raingeaud, J.1
Whitmarsh, A.2
Barrett, T.3
Derijard, B.4
Davis, R.5
-
32
-
-
0035813157
-
Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells
-
Re F, Strominger J. Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells. J Biol Chem. 2001;276:37692-37699.
-
(2001)
J Biol Chem
, vol.276
, pp. 37692-37699
-
-
Re, F.1
Strominger, J.2
-
33
-
-
0035869634
-
A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-α, and contact sensitizers
-
Arrighi J-F, Rebsamen M, Rousset F, Kindler V, Hauser C. A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-α, and contact sensitizers. J Immunol. 2001;166:3837-3845.
-
(2001)
J Immunol
, vol.166
, pp. 3837-3845
-
-
Arrighi, J.-F.1
Rebsamen, M.2
Rousset, F.3
Kindler, V.4
Hauser, C.5
-
34
-
-
0037114185
-
A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling
-
Yamamoto M, Sato S, Mori K, et al. A novel Toll/ IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling. J Immunol. 2002;169:6668-6672.
-
(2002)
J Immunol
, vol.169
, pp. 6668-6672
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
-
36
-
-
0034046786
-
Interleukin 1 and cutaneous inflammation: A crucial link between innate and acquired Immunity
-
Murphy JE, Robert C, Kupper T. Interleukin 1 and cutaneous inflammation: a crucial link between innate and acquired Immunity. J Invest Dermatol. 2000;114:602-608.
-
(2000)
J Invest Dermatol
, vol.114
, pp. 602-608
-
-
Murphy, J.E.1
Robert, C.2
Kupper, T.3
-
37
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the LPS gene product
-
Hoshino K, Takeuchi O, Kawal T, et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the LPS gene product. J Immunol. 1999;162:3749-3752.
-
(1999)
J Immunol
, vol.162
, pp. 3749-3752
-
-
Hoshino, K.1
Takeuchi, O.2
Kawal, T.3
-
38
-
-
0034976848
-
Different Toll-like receptor agonists induce distinct macrophage responses
-
Jones B, Means T, Heldwein K, et al. Different Toll-like receptor agonists induce distinct macrophage responses. J Leukoc Biol. 2001;69:1036-1044.
-
(2001)
J Leukoc Biol
, vol.69
, pp. 1036-1044
-
-
Jones, B.1
Means, T.2
Heldwein, K.3
-
39
-
-
0036088492
-
Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
-
Jurk M, Hell F, Vollmer J, et al. Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat Immunol. 2002;3:499.
-
(2002)
Nat Immunol
, vol.3
, pp. 499
-
-
Jurk, M.1
Hell, F.2
Vollmer, J.3
-
40
-
-
0034457684
-
Cloning and characterization of a sub-family of human toll-like receptors: HTLR7, hTLR8 and hTLR9
-
Chaung TH, Ulevitch R. Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9. Eur Cytokine Netw. 2000;11:372-378.
-
(2000)
Eur Cytokine Netw
, vol.11
, pp. 372-378
-
-
Chaung, T.H.1
Ulevitch, R.2
-
41
-
-
0036570169
-
Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
Hornung V, Rothenfusser S, Britsch S, et al. Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol. 2002;168:4531-4537.
-
(2002)
J Immunol
, vol.168
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
-
43
-
-
0035179882
-
Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
-
Jarrossay D, Napolitani G, Colonna M, Sallusto F, Lanzavecchia A. Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur J Immunol. 2001;31:3388-3393.
-
(2001)
Eur J Immunol
, vol.31
, pp. 3388-3393
-
-
Jarrossay, D.1
Napolitani, G.2
Colonna, M.3
Sallusto, F.4
Lanzavecchia, A.5
-
44
-
-
18744409038
-
Plasmacytoid dendritic cells: A new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases
-
Wollengerg A, Wagner M, Gunther S, et al. Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases. J Invest Dermatol. 2002;119:1096-1102.
-
(2002)
J Invest Dermatol
, vol.119
, pp. 1096-1102
-
-
Wollengerg, A.1
Wagner, M.2
Gunther, S.3
-
45
-
-
0036924110
-
Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod
-
Gibson S, Lindh J, Riter T, et al. Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod. Cell Immunol. 2002;218:74-86.
-
(2002)
Cell Immunol
, vol.218
, pp. 74-86
-
-
Gibson, S.1
Lindh, J.2
Riter, T.3
|