DNA microarray analysis of hippocampal gene expression measured twelve hours after hypoxia-ischemia in the mouse

Journal of Cerebral Blood Flow and Metabolism

Volumn 23, Issue 10, 2003, Pages 1195-1211

  Gilbert, Robert W ^a   Costain, Willard J ^a   Blanchard, Marie Eve ^a   Mullen, Kerry L ^a   Currie, R William ^b   Robertson, Harold A ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Gene expression; Gene ontology; Hippocampus; HypoxiaIschemia; Mice; Microarray

Indexed keywords

CALCIUM BINDING PROTEIN; CHAPERONE; PHOSPHOTRANSFERASE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; CELL DEATH; CELL STRUCTURE; CONTROLLED STUDY; DNA MICROARRAY; EXPRESSED SEQUENCE TAG; GENE; GENE CLUSTER; GENE EXPRESSION; GENOME; HIPPOCAMPUS; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0141994809     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.WCB.0000088763.02615.79     Document Type: Article

References (62)

1. Aoki M, Abe K, Kawagoe J, Sato S, Nakamura S, Kogure K (1993) Temporal profile of the induction of heat shock protein 70 and heat shock cognate protein 70 mRNAs after transient ischemia in gerbil brain. Brain Res 601:185-192
2. Babity JM, Newton RA, Guido ME, Robertson HA (1997) The application of differential display to the brain. Adaptations for the study of heterogeneous tissue. Methods Mol Biol 85:285-295
3. Beere HM, Green DR (2001) Stress management-heat shock protein-70 and the regulation of apoptosis. Trends Cell Biol 11:6-10
4. Beere HM, Wolf BB, Cain K, Mosser DD, Mahboubi A, Kuwana T, Tailor P, Morimoto RI, Cohen GM, Green DR (2000) Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat Cell Biol 2:469-475
5. Bernaudin M, Tang Y, Reilly M, Petit E, Sharp FR (2002) Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance. J Biol Chem 277:39728-39738
6. Bruey JM, Ducasse C, Bonniaud P, Ravagnan L, Susin SA, Diaz-Latoud C, Gurbuxani S, Arrigo AP, Kroemer G, Solary E, Garrido C (2000) Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat Cell Biol 2:645-652
7. Buzzard KA, Giaccia AJ, Killender M, Anderson RL (1998) Heat shock protein 72 modulates pathways of stress-induced apoptosis. J Biol Chem 273:17147-17153
8. Chan EY, Luthi-Carter R, Strand A, Solano SM, Hanson SA, DeJohn MM, Kooperberg C, Chase KO, DiFiglia M, Young AB, Leavitt BR, Cha JH, Aronin N, Hayden MR, Olson JM (2002) Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. Hum Mol Genet 11:1939-1951
9. Chen J, Simon R (1997) Ischemic tolerance in the brain. Neurology 48:306-311
10. Colangelo V, Schurr J, Ball MJ, Pelaez RP, Bazan NG, Lukiw WJ (2002) Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor downregulation and up-regulation of apoptotic and pro-inflammatory signaling. J Neurosci Res 70:462-473
11. Colbourne F, Sutherland GR, Auer RN (1999) Electron microscopic evidence against apoptosis as the mechanism of neuronal death in global ischemia. J Neurosci 1999 19:4200-4210
12. Currie RW, Plumier JC (1998) The heat shock response and tissue protection. In: Delayed preconditioning and adaptive cardioprotection (Baxter GF, Yellon DM, eds), Boston, MA: Kluwer Academic Publishers, pp 135-153
13. Denovan-Wright EM, Newton RA, Armstrong JN, Babity JM, Robertson HA (1998) Acute administration of cocaine, but not amphetamine, increases the level of synaptotagmin IV mRNA in the dorsal striatum of rat. Brain Res Mol Brain Res 55:350-354
14. Gotoh T, Terada K, Mori M (2001) hsp70-DnaJ chaperone pairs prevent nitric oxide-mediated apoptosis in RAW 264.7 macrophages. Cell Death Differ 8:357-366
15. Grunblatt E, Mandel S, Maor G, Youdim MB (2001) Gene expression analysis in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: mice model of Parkinson's disease using cDNA microarray: effect of R-apomorphine. J Neurochem 78:1-12
16. Hatayama T, Yamagishi N, Minobe E, Sakai K (2001) Role of hsp105 in protection against stress-induced apoptosis in neuronal PC12 cells. Biochem Biophys Res Commun 288:528-534
17. Hylander BL, Chen X, Graf PC, Subjeck JR (2000) The distribution and localization of hsp110 in brain. Brain Res 869:49-55
18. Itoh H, Kobayashi R, Wakui H, Komatsuda A, Ohtani H, Miura AB, Otaka M, Masamune O, Andoh H, Koyama K, et al. (1995) Mammallan 60-kDa stress protein (chaperonin homolog). Identification, biochemical properties, and localization. J Biol Chem 270:13429-13435
19. Izaki K, Kinouchi H, Watanabe K, Owada Y, Okubo A, Itoh H, Kondo H, Tashima Y, Tamura S, Yoshimoto T, Mizoi K (2001) Induction of mitochondrial heat shock protein 60 and 10 mRNAs following transient focal cerebral ischemia in the rat. Brain Res Mol Brain Res 88:14-25
20. Jin K, Mao XO, Eshoo MW, Nagayama T, Minami M, Simon RP, Greenberg DA (2001) Microarray analysis of hippocampal gene expression in global cerebral ischemia. Ann Neurol 50:93-103
21. Jonsson H, Johnsson P, Birch-Iensen M, Alling C, Westaby S, Blomquist S (2001) S100B as a predictor of size and outcome of stroke after cardiac surgery. Ann Thorac Surg 71:1433-1437
22. Kargul GJ, Dudekula DB, Qian Y, Lim MK, Jaradat SA, Tanaka TS, Carter MG, Ko MS (2001) Verification and initial annotation of the NIA mouse 15K cDNA clone set. Nat Genet 28:17-18
23. Kawagoe J, Abe K, Aoki M, Kogure K (1993) Induction of HSP90 alpha heat shock mRNA after transient global ischemia in gerbil hippocampus. Brain Res 621:121-125
24. Kim YD, Sohn NW, Kang C, Soh Y (2002) DNA array reveals altered gene expression in response to focal cerebral ischemia. Brain Res Bull 58:491-498
25. Kulkarni MS, Daggett JL, Bender TP, Kuehl WM, Bergsagel PL, Williams ME (2002) Frequent inactivation of the cyclin-dependent kinase inhibitor p18 by homozygous deletion in multiple myeloma cell lines: ectopic p18 expression inhibits growth and induces apoptosis. Leukemia 16:127-134
26. Kumagai J, Fukuda J, Kodama H, Murata M, Kawamura K, Itoh H, Tanaka T (2000) Germ cell-specific heat shock protein 105 binds to p53 in a temperature-sensitive manner in rat testis. Eur J Biochem 267:3073-3078
27. Lau S, Patnaik N, Sayen MR, Mestril R (1997) Simultaneous overexpression of two stress proteins in rat cardiomyocytes and myogenic cells confers protection against ischemia-induced injury. Circulation 96:2287-2294
28. Lee CK, Weindruch R, Prolla TA (2000) Gene-expression profile of the ageing brain in mice. Nat Genet 25:294-297
29. Loring JF, Wen X, Lee JM, Seilhamer J, Somogyi R (2001) A gene expression profile of Alzheimer's disease. DNA Cell Biol 20:683-695
30. Majda BT, Meloni BP, Rixon N, Knuckey NW (2001) Suppression subtraction hybridization and northern analysis reveal upregulation of heat shock, trkB, and sodium calcium exchanger genes following global cerebral ischemia in the rat. Brain Res Mol Brain Res 93:173-179
31. Matsumori M, Itoh H, Toyoshima I, Komatsuda A, Sawada K, Fukuda J, Tanaka T, Okubo A, Kinouchi H, Mizoi K, Hama T, Suzuki A, Hamada F, Otaka M, Shoji Y, Takada G (2002) Characterization of the 105-kDa molecular chaperone. Identification, biochemical properties, and localization. Eur J Biochem 269:5632-5641
32. Matzilevich DA, Rall JM, Moore AN, Grill RJ, Dash PK (2002) High-density microarray analysis of hippocampal gene expression following experimental brain injury. J Neurosci Res 67:646-663
33. Mehlen P, Schulze-Osthoff K, Arrigo AP (1996) Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death. J Biol Chem 271:16510-16514
34. Moore SK, Kozak C, Robinson EA, Ullrich SJ, Appella E (1989) Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins. J Biol Chem 264:5343-5351
35. Mosser DD, Caron AW, Bourget L, Denis-Larose C, Massie B (1997) Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis. Mol Cell Biol 17:5317-5327
36. Naylor DJ, Stines AP, Hoogenraad NJ, Hoj PB (1998) Evidence for the existence of distinct mammalian cytosolic, microsomal, and two mitochondrial GrpE-like proteins, the Co-chaperones of specific Hsp70 members. J Biol Chem 273:21169-21177
37. O'Donnell SL, Frederick TJ, Krady JK, Vannucci SJ, Wood TL (2002) IGF-I and microglia/macrophage proliferation in the ischemic mouse brain. Glia 39:85-97
38. Okubo A, Kinouchi H, Owada Y, Kunizuka H, Itoh H, Izaki K, Kondo H, Tashima Y, Yoshimoto T, Mizoi K. (2000) Simultaneous induction of mitochondrial heat shock protein mRNAs in rat forebrain ischemia. Brain Res Mol Brain Res 84:127-134
39. Paschen W, Linden T, Doutheil J (1998) Effects of transient cerebral ischemia on hsp40 mRNA levels in rat brain. Brain Res Mol Brain Res 55:341-344
40. Pasinetti GM (2001) Use of cDNA microarray in the search for molecular markers involved in the onset of Alzheimer's disease dementia. J Neurosci Res 65:471-476
41. Pasinetti GM, Ho L (2001) From cDNA microarrays to high-throughput proteomics. Implications in the search for preventive initiatives to slow the clinical progression of Alzheimer's disease dementia. Restor Neurol Neurosci 18:137-142
42. Perkins AS (2002) Functional genomics in the mouse. Funct Integr Genomics 2:81-91
43. Read SJ, Parsons AA, Harrison DC, Philpott K, Kabnick K, S OB, Clark S, Brawner M, Bates S, Gloger I, Legos JJ, Barone FC (2001) Stroke genomics: approaches to identify, validate, and understand ischemic stroke gene expression. J Cereb Blood Flow Metab 21:755-778
44. Rice JE, 3rd, Vannucci RC, Brierley JB (1981) The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann Neurol 9:131-141
45. Samali A, Cotter TG (1996) Heat shock proteins increase resistance to apoptosis. Exp Cell Res 223:163-170
46. Sato S, Fujita N, Tsuruo T (2000) Modulation of Akt kinase activity by binding to Hsp90. Proc Natl Acad Sci U S A 97:10832-10837
47. Schmidt-Kastner R, Zhang B, Belayev L, Khoutorova L, Amin R, Busto R, Ginsberg MD (2002) DNA microarray analysis of cortical gene expression during early recirculation after focal brain ischemia in rat. Brain Res Mol Brain Res 108:81-93
48. Sipione S, Rigamonti D, Valenza M, Zuccato C, Conti L, Pritchard J, Kooperberg C, Olson JM, Cattaneo E (2002) Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses. Hum Mol Genet 11:1953-1965
49. Soriano MA, Tessier M, Certa U, Gill R (2000) Parallel gene expression monitoring using oligonucleotide probe arrays of multiple transcripts with an animal model of focal ischemia. J Cereb Blood Flow Metab 20:1045-1055
50. Stanton LW, Garrard LJ, Damm D, Garrick BL, Lam A, Kapoun AM, Zheng Q, Protter AA, Schreiner GF, White RT (2000) Altered patterns of gene expression in response to myocardial infarction. Circ Res 86:939-945
51. Stuart JK, Myszka DG, Joss L, Mitchell RS, McDonald SM, Xie Z, Takayama S, Reed JC, Ely KR (1998) Characterization of interactions between the anti-apoptotic protein BAG-1 and Hsc70 molecular chaperones. J Biol Chem 273:22506-22514
52. Tamura S, Kinouchi H, Izaki K, Okubo A, Sugawara T, Kunizuka H, Mizoi K (2003) Induction of heat shock protein 40 and GrpE mRNAs following transient focal cerebral ischemia in the rat. Brain Res 960:277-281
53. Tanaka S, Kitagawa K, Ohtsuki T, Yagita Y, Takasawa K, Hori M, Matsumoto M (2002) Synergistic induction of HSP40 and HSC70 in the mouse hippocampal neurons after cerebral ischemia and ischemic tolerance in gerbil hippocampus. J Neurosci Res 67:37-47
54. Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98:5116-5121
55. Vannucci SJ, Seaman LB, Vannucci RC (1996) Effects of hypoxia-ischemia on GLUT1 and GLUT3 glucose transporters in immature rat brain. J Cereb Blood Flow Metab 16:77-81
56. Vannucci SJ, Willing LB, Goto S, Alkayed NJ, Brucklacher RM, Wood TL, Towfighi J, Hum PD, Simpson IA (2001) Experimental stroke in the female diabetic, db/db, mouse. J Cereb Blood Flow Metab 21:52-60
57. Wagstaff MJ, Collaco-Moraes Y, Aspey BS, Coffin RS, Harrison MJ, Latchman DS, de Belleroche JS (1996) Focal cerebral ischemia increases the levels of several classes of heat shock proteins and their corresponding mRNAs. Brain Res Mol Brain Res 42:236-244
58. Welch WJ (1992) Mammalian stress response: cell physiology, structure/function of stress proteins, and implications for medicine and disease. Physiol Rev 72:1063-1081
59. Xue JH, Fukuyama H, Nonoguchi K, Kaneko Y, Kido T, Fukumoto M, Fujibayashi Y, Itoh K, Fujita J (1998) Induction of Apg-1, a member of the heat shock protein 110 family, following transient forebrain ischemia in the rat brain. Biochem Biophys Res Commun 247:796-801
60. Yagita Y, Kitagawa K, Ohtsuki T, Tanaka S, Hori M, Matsumoto M (2001) Induction of the HSP110/105 family in the rat hippocampus in cerebral ischemia and ischemic tolerance. J Cereb Blood Flow Metab 21:811-819
61. Yang YH, Speed T (2002) Design issues for cDNA microarray experiments. Nat Rev Genet 3:579-588
62. Yokota N, Uchijima M, Nishizawa S, Namba H, Koide Y (2001) Identification of differentially expressed genes in rat hippocampus after transient global cerebral ischemia using subtractive cDNA cloning based on polymerase chain reaction. Stroke 32:168-174