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Volumn 171, Issue 8, 2003, Pages 4203-4209

Phosphatidylcholine-specific phospholipase C activity is necessary for the activation of STAT6

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 4; JANUS KINASE; PERVANADATE; PHOSPHATIDYLCHOLINE SPECIFIC PHOSPHOLIPASE C; PHOSPHOLIPASE C; STAT6 PROTEIN; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL LIPASE; TUMOR NECROSIS FACTOR ALPHA; TYROSINE; UNCLASSIFIED DRUG; VANADATE SODIUM;

EID: 0141992862     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.8.4203     Document Type: Article
Times cited : (15)

References (54)
  • 1
    • 0025764757 scopus 로고
    • Interleukin 4: A prototypic immunoregulatory cytokine
    • Paul, W. E. 1991. Interleukin 4: a prototypic immunoregulatory cytokine. Blood 77:1859.
    • (1991) Blood , vol.77 , pp. 1859
    • Paul, W.E.1
  • 2
    • 0021821215 scopus 로고
    • B-cell growth factor (B-cell growth factor 1 or B-cell-stimulating factor, provisional 1) is a differentiation factor for resting B cells and may not induce cell growth
    • Oliver, K., R. J. Noelle, J. W. Uhr, P. H. Krammer, and E. S. Vitetta. 1985. B-cell growth factor (B-cell growth factor 1 or B-cell-stimulating factor, provisional 1) is a differentiation factor for resting B cells and may not induce cell growth. Proc. Natl. Acad. Sci. USA 82:2465.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 2465
    • Oliver, K.1    Noelle, R.J.2    Uhr, J.W.3    Krammer, P.H.4    Vitetta, E.S.5
  • 3
    • 0022353594 scopus 로고
    • Serological, biochemical, and functional identity of B-cell stimulatory factor-1 and B cell differentiation factor for IgG1
    • Vitetta, E. S., J. Ohara, C. Myers, J. Layton, P. H. Krammer, and W. E. Paul. 1985. Serological, biochemical, and functional identity of B-cell stimulatory factor-1 and B cell differentiation factor for IgG1. J. Exp. Med. 162:1726.
    • (1985) J. Exp. Med. , vol.162 , pp. 1726
    • Vitetta, E.S.1    Ohara, J.2    Myers, C.3    Layton, J.4    Krammer, P.H.5    Paul, W.E.6
  • 4
    • 0030444051 scopus 로고    scopus 로고
    • IL-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway
    • Zamorano, J., H. Y. Wang, L.-M. Wang, J. H. Pierce, and A. D. Keegan. 1996. IL-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway. J. Immunol. 157:4926.
    • (1996) J. Immunol. , vol.157 , pp. 4926
    • Zamorano, J.1    Wang, H.Y.2    Wang, L.-M.3    Pierce, J.H.4    Keegan, A.D.5
  • 6
    • 0032007351 scopus 로고    scopus 로고
    • IL-13, IL-4Rα, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite N. brasiliensis
    • Urban, J. F., N. Noben-Trauth, D. D. Donaldson, K. B. Madden, S. C. Morris, M. Collins, and F. D. Finkelman. 1998. IL-13, IL-4Rα, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite N. brasiliensis. Immunity 8:255.
    • (1998) Immunity , vol.8 , pp. 255
    • Urban, J.F.1    Noben-Trauth, N.2    Donaldson, D.D.3    Madden, K.B.4    Morris, S.C.5    Collins, M.6    Finkelman, F.D.7
  • 7
    • 0032522641 scopus 로고    scopus 로고
    • An antagonistic IL-4 mutant prevent type I allergy in the mouse: Inhibition of the IL-4/IL-13 receptor system completely abrogates humoral immune response to allergen and development of allergic symptoms in vivo
    • Grunewald, S. M., A. Werthmann, B. Schnarr, C. E. Klein, E. B. Brocker, M. Mohrs, F. Brombacher, W. Sebald, and A. Duschl. 1998. An antagonistic IL-4 mutant prevent type I allergy in the mouse: inhibition of the IL-4/IL-13 receptor system completely abrogates humoral immune response to allergen and development of allergic symptoms in vivo. J. Immunol. 160:4004.
    • (1998) J. Immunol. , vol.160 , pp. 4004
    • Grunewald, S.M.1    Werthmann, A.2    Schnarr, B.3    Klein, C.E.4    Brocker, E.B.5    Mohrs, M.6    Brombacher, F.7    Sebald, W.8    Duschl, A.9
  • 11
    • 0031015594 scopus 로고    scopus 로고
    • Cloning of the human IL-13Rα1 chain and reconstitution with the IL4Rα of a functional IL-4/IL-13 receptor complex
    • Miloux, B., P. Laurent, O. Bonnin, J. Lupker, D. Caput, N. Vita, and P. Ferrara. 1997. Cloning of the human IL-13Rα1 chain and reconstitution with the IL4Rα of a functional IL-4/IL-13 receptor complex. FEBS Lett. 401:16.
    • (1997) FEBS Lett. , vol.401 , pp. 16
    • Miloux, B.1    Laurent, P.2    Bonnin, O.3    Lupker, J.4    Caput, D.5    Vita, N.6    Ferrara, P.7
  • 12
    • 0001606677 scopus 로고    scopus 로고
    • Jak1 expression is required for mediating interleukin-4-induced tyrosine phosphorylation of insulin receptor substrate and Stat6 signaling molecules
    • Chen, X. H., B. K. Patel, L. M. Wang, M. Frankel, N. Ellmore, R. A. Flavell, W. J. LaRochelle, and J. H. Pierce. 1997. Jak1 expression is required for mediating interleukin-4-induced tyrosine phosphorylation of insulin receptor substrate and Stat6 signaling molecules. J. Biol. Chem. 272:6556.
    • (1997) J. Biol. Chem. , vol.272 , pp. 6556
    • Chen, X.H.1    Patel, B.K.2    Wang, L.M.3    Frankel, M.4    Ellmore, N.5    Flavell, R.A.6    LaRochelle, W.J.7    Pierce, J.H.8
  • 14
    • 0027507755 scopus 로고
    • IRS-1: Essential for insulin and IL-4-stimulated mitogenesis in hematopoietic cells
    • Wang, L.-M., M. G. Myers, X.-J. Sun, S. A. Aaronson, M. White, and J. H. Pierce. 1993. IRS-1: essential for insulin and IL-4-stimulated mitogenesis in hematopoietic cells. Science 261:1591.
    • (1993) Science , vol.261 , pp. 1591
    • Wang, L.-M.1    Myers, M.G.2    Sun, X.-J.3    Aaronson, S.A.4    White, M.5    Pierce, J.H.6
  • 15
    • 0032528425 scopus 로고    scopus 로고
    • Regulation of apoptosis by tyrosine-containing domains of IL-4Rα: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis
    • Zamorano, J., and A. D. Keegan. 1998. Regulation of apoptosis by tyrosine-containing domains of IL-4Rα: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis. J. Immunol. 161:859.
    • (1998) J. Immunol. , vol.161 , pp. 859
    • Zamorano, J.1    Keegan, A.D.2
  • 16
    • 0029057858 scopus 로고
    • Cloning of murine STAT6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis
    • Quelle, F. W., K. Shimoda, W. Thierfelder, C. Fischer, A. Kim, S. M. Ruben, J. L. Cleveland, J. H. Pierce, A. D. Keegan, K. Nelms, et al. 1995. Cloning of murine STAT6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis. Mol. Cell. Biol. 15:3336.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3336
    • Quelle, F.W.1    Shimoda, K.2    Thierfelder, W.3    Fischer, C.4    Kim, A.5    Ruben, S.M.6    Cleveland, J.L.7    Pierce, J.H.8    Keegan, A.D.9    Nelms, K.10
  • 18
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell, J. E. 1997. STATs and gene regulation. Science 277:1630.
    • (1997) Science , vol.277 , pp. 1630
    • Darnell, J.E.1
  • 19
    • 0032529410 scopus 로고    scopus 로고
    • Characterization of a mobile Stat-6 motif in the human IL-4 receptor
    • Ryan, J. J., L. J. McReynolds, H. Huang, K. Nelms, and W. E. Paul. 1998. Characterization of a mobile Stat-6 motif in the human IL-4 receptor. J. Immunol. 161:1811.
    • (1998) J. Immunol. , vol.161 , pp. 1811
    • Ryan, J.J.1    McReynolds, L.J.2    Huang, H.3    Nelms, K.4    Paul, W.E.5
  • 20
    • 0037184088 scopus 로고    scopus 로고
    • Analysis of the life cycle of Stat6: Continuous cycling of Stat6 is required for IL-4 signaling
    • Andrews, R. P., M. B. Ericksen, C. M. Cunningham, M. O. Daines, and G. K. Hershey. 2002. Analysis of the life cycle of Stat6: continuous cycling of Stat6 is required for IL-4 signaling. J. Biol. Chem. 277:36563.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36563
    • Andrews, R.P.1    Ericksen, M.B.2    Cunningham, C.M.3    Daines, M.O.4    Hershey, G.K.5
  • 21
    • 0037423215 scopus 로고    scopus 로고
    • Regulation of the de-phosphorylation of STAT6: Participation of Y713 in the IL-4Rα, the tyrosine phosphatase SHP-1. and the proteasome
    • Hanson, E. M., H. Dickensheets, C. K. Qu, R. P. Donnelly, and A. D. Keegan. 2003. Regulation of the de-phosphorylation of STAT6: participation of Y713 in the IL-4Rα, the tyrosine phosphatase SHP-1. and the proteasome. J. Biol. Chem. 275:3903.
    • (2003) J. Biol. Chem. , vol.275 , pp. 3903
    • Hanson, E.M.1    Dickensheets, H.2    Qu, C.K.3    Donnelly, R.P.4    Keegan, A.D.5
  • 23
    • 0034650951 scopus 로고    scopus 로고
    • Interleukin-4-induced transcriptional activation by STAT6 involves multiple serine/threonine kinase pathways and serine phosphorylation of STAT6
    • Pesu, M., K. Takaluoma, S. Aittomaki, A. Lagerstedt, K. Saksela, P. E. Kovanen, and O. Silvennoinen. 2000. Interleukin-4-induced transcriptional activation by STAT6 involves multiple serine/threonine kinase pathways and serine phosphorylation of STAT6. Blood 95:494.
    • (2000) Blood , vol.95 , pp. 494
    • Pesu, M.1    Takaluoma, K.2    Aittomaki, S.3    Lagerstedt, A.4    Saksela, K.5    Kovanen, P.E.6    Silvennoinen, O.7
  • 25
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
    • O'Shea, J. J., M. Gadina, and R. D. Schreiber. 2002. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 109:S121.
    • (2002) Cell , vol.109
    • O'Shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 26
    • 0036467550 scopus 로고    scopus 로고
    • Aspirin and salicylates inhibit the IL-4- and IL-13-induced activation of STAT6
    • Perez-G, M., M. Melo, A. D. Keegan, and J. Zamorano, 2002. Aspirin and salicylates inhibit the IL-4- and IL-13-induced activation of STAT6. J. Immunol. 168:1428.
    • (2002) J. Immunol. , vol.168 , pp. 1428
    • Perez-G, M.1    Melo, M.2    Keegan, A.D.3    Zamorano, J.4
  • 27
    • 0035213428 scopus 로고    scopus 로고
    • NF-κB activation plays an important role in the IL-4-induced protection from apoptosis
    • Zamorano, J., A. L. Mora, M. Boothby, and A. D. Keegan. 2001. NF-κB activation plays an important role in the IL-4-induced protection from apoptosis. Int. Immunol. 13:1479.
    • (2001) Int. Immunol. , vol.13 , pp. 1479
    • Zamorano, J.1    Mora, A.L.2    Boothby, M.3    Keegan, A.D.4
  • 28
    • 0026458406 scopus 로고
    • TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown
    • Schutze, S., K. Potthoff, T. Machleidt, D. Berkovic, K. Wiegmann, and M. Kronke. 1992. TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell 71:765.
    • (1992) Cell , vol.71 , pp. 765
    • Schutze, S.1    Potthoff, K.2    Machleidt, T.3    Berkovic, D.4    Wiegmann, K.5    Kronke, M.6
  • 29
    • 0027938509 scopus 로고
    • Interleukin 4 receptor signaling in human monocytes and U937 cells involves the activation of a phosphatidylcholine-specific phospholipase C: A comparison with chemotactic peptide, FMLP, phospholipase D, and sphingomyelinase
    • Ho, J. L., B. Zhu, S. He, B. Du, and R. Rothman. 1994. Interleukin 4 receptor signaling in human monocytes and U937 cells involves the activation of a phosphatidylcholine-specific phospholipase C: a comparison with chemotactic peptide, FMLP, phospholipase D, and sphingomyelinase. J. Exp. Med. 180:1457.
    • (1994) J. Exp. Med. , vol.180 , pp. 1457
    • Ho, J.L.1    Zhu, B.2    He, S.3    Du, B.4    Rothman, R.5
  • 30
    • 0026710617 scopus 로고
    • Peroxides of vanadate induce activation of phospholipase D in HL-60 cell: Role of tyrosine phosphorylation
    • Bourgoin, S., and S. Grinstein. 1992. Peroxides of vanadate induce activation of phospholipase D in HL-60 cell: role of tyrosine phosphorylation. J. Biol. Chem. 267:11908.
    • (1992) J. Biol. Chem. , vol.267 , pp. 11908
    • Bourgoin, S.1    Grinstein, S.2
  • 31
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction
    • Bligh, E. G., and W. J. Dyer. 1959. A rapid method of total lipid extraction. Can. Biochem. J. Physiol. 37:911.
    • (1959) Can. Biochem. J. Physiol. , vol.37 , pp. 911
    • Bligh, E.G.1    Dyer, W.J.2
  • 32
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
    • Scheinman, R. I., P. C. Cogswell, A. K. Lofquist, and A. S. Baldwin, Jr. 1995. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science 270:283.
    • (1995) Science , vol.270 , pp. 283
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin A.S., Jr.4
  • 33
    • 0030805604 scopus 로고    scopus 로고
    • Cyclosporine A is an uncompetitive inhibitor of proteasome activity and prevents NF-κB activation
    • Meyer, S., N. G. Kohler, and A. Joly. 1997. Cyclosporine A is an uncompetitive inhibitor of proteasome activity and prevents NF-κB activation. FEBS Lett. 413:354.
    • (1997) FEBS Lett. , vol.413 , pp. 354
    • Meyer, S.1    Kohler, N.G.2    Joly, A.3
  • 34
    • 0029006149 scopus 로고
    • Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence
    • Lin, Y. Z., S. Y. Yao, R. A. Veach, T. R. Torgerson, and J. Hawiger. 1995. Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J. Biol. Chem. 270:14255.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14255
    • Lin, Y.Z.1    Yao, S.Y.2    Veach, R.A.3    Torgerson, T.R.4    Hawiger, J.5
  • 35
    • 0024327349 scopus 로고
    • Interruption of TPA-induced signals by an antiviral and antitumoral xanthate compound: Inhibition of a phospholipase C-type reaction
    • Muller-Decker, K. 1989. Interruption of TPA-induced signals by an antiviral and antitumoral xanthate compound: inhibition of a phospholipase C-type reaction. Biochem. Biophys. Res. Commun. 162:198.
    • (1989) Biochem. Biophys. Res. Commun. , vol.162 , pp. 198
    • Muller-Decker, K.1
  • 36
    • 0028790464 scopus 로고
    • Compound D609 inhibits phorbol ester-stimulated phospholipase D activity and phospholipase C-mediated phosphatidylethanolamine hydrolysis
    • Kiss, Z., and M. Tomono. 1995. Compound D609 inhibits phorbol ester-stimulated phospholipase D activity and phospholipase C-mediated phosphatidylethanolamine hydrolysis. Biochim. Biophys. Acta 1259:105.
    • (1995) Biochim. Biophys. Acta , vol.1259 , pp. 105
    • Kiss, Z.1    Tomono, M.2
  • 37
    • 0026742177 scopus 로고
    • Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues
    • Powis, G., M. J. Seewald, C. Gratas, D. Melder, J. Riebow, and E. J. Modest. 1992. Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues. Cancer Res. 52:2835.
    • (1992) Cancer Res. , vol.52 , pp. 2835
    • Powis, G.1    Seewald, M.J.2    Gratas, C.3    Melder, D.4    Riebow, J.5    Modest, E.J.6
  • 38
    • 0025737675 scopus 로고
    • Inhibition of neural phospholipase D activity by aminoglycoside antibiotics
    • Liscovitch, M., V. Chalifa, M. Danin, and Y. Eli. 1991. Inhibition of neural phospholipase D activity by aminoglycoside antibiotics. Biochem. J. 279:319.
    • (1991) Biochem. J. , vol.279 , pp. 319
    • Liscovitch, M.1    Chalifa, V.2    Danin, M.3    Eli, Y.4
  • 39
    • 0031452912 scopus 로고    scopus 로고
    • Phosphatidylcholine-specific phospholipase C regulates thapsigargin-induced calcium influx in human lymphocytes
    • Nofer, J. R., M. Tepel, M. Walter, U. Seedorf, G. Assmann, and W. Zidek. 1997. Phosphatidylcholine-specific phospholipase C regulates thapsigargin-induced calcium influx in human lymphocytes. J. Biol. Chem. 272:32861.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32861
    • Nofer, J.R.1    Tepel, M.2    Walter, M.3    Seedorf, U.4    Assmann, G.5    Zidek, W.6
  • 40
    • 0028296793 scopus 로고
    • Phosphatidylcholine breakdown and signal transduction
    • Exton, J. H. 1994. Phosphatidylcholine breakdown and signal transduction. Biochim. Biophys. Acta 1212:26.
    • (1994) Biochim. Biophys. Acta , vol.1212 , pp. 26
    • Exton, J.H.1
  • 41
    • 0031036888 scopus 로고    scopus 로고
    • ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3′-kinase through an extracellular site: Synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate
    • Chung, T., K. S. Crilly, W. H. Anderson, J. J. Mukherjee, and Z. Kiss. 1997. ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3′-kinase through an extracellular site: synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate. J. Biol. Chem. 272:3064.
    • (1997) J. Biol. Chem. , vol.272 , pp. 3064
    • Chung, T.1    Crilly, K.S.2    Anderson, W.H.3    Mukherjee, J.J.4    Kiss, Z.5
  • 42
    • 0033010661 scopus 로고    scopus 로고
    • Genetic analysis of B cell antigen receptor signaling
    • Kurosaki, T. 1999. Genetic analysis of B cell antigen receptor signaling. Annu. Rev. Immunol. 17:555.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 555
    • Kurosaki, T.1
  • 43
    • 0030978808 scopus 로고    scopus 로고
    • Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines
    • Nielsen, M., K. Kaltoft, M. Nordahl, C. Ropke, C. Geirler, T. Mustelin, P. Dobson, A. Svejgaard, and N. Odum. 1997. Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines. Proc. Natl. Acad. Sci. USA 94:6764.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6764
    • Nielsen, M.1    Kaltoft, K.2    Nordahl, M.3    Ropke, C.4    Geirler, C.5    Mustelin, T.6    Dobson, P.7    Svejgaard, A.8    Odum, N.9
  • 47
    • 0028791664 scopus 로고
    • Roles of protein-tyrosine phosphatases in Stat1α-mediated cell signaling
    • Haque, S. J., V. Flati, A. Deb, and B. R. Williams. 1995. Roles of protein-tyrosine phosphatases in Stat1α-mediated cell signaling. J. Biol. Chem. 270:25709.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25709
    • Haque, S.J.1    Flati, V.2    Deb, A.3    Williams, B.R.4
  • 48
    • 0027418831 scopus 로고
    • In vitro activation of the transcription factor ISGF3 by interferon-α involves a membrane-associated tyrosine phosphatase and tyrosine kinase
    • David, M., G. Romero, Z. Y. Zhang, J. E. Dixon, and A. C. Larner. 1993. In vitro activation of the transcription factor ISGF3 by interferon-α involves a membrane-associated tyrosine phosphatase and tyrosine kinase. J. Biol. Chem. 268:6593.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6593
    • David, M.1    Romero, G.2    Zhang, Z.Y.3    Dixon, J.E.4    Larner, A.C.5
  • 49
    • 0030583720 scopus 로고    scopus 로고
    • Vanadate is a potent competitive inhibitor of phospholipase C from Bacillus cereus
    • Tan, C. A., and M. F. Roberts. 1996. Vanadate is a potent competitive inhibitor of phospholipase C from Bacillus cereus. Biochim. Biophys. Acta 1298:58.
    • (1996) Biochim. Biophys. Acta , vol.1298 , pp. 58
    • Tan, C.A.1    Roberts, M.F.2
  • 50
    • 0034142220 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase activity is required for IL-4 induction of IL-4 receptor α-chain
    • Huang, H., and W. E. Paul. 2000. Protein tyrosine phosphatase activity is required for IL-4 induction of IL-4 receptor α-chain. J. Immunol. 164:1211.
    • (2000) J. Immunol. , vol.164 , pp. 1211
    • Huang, H.1    Paul, W.E.2
  • 51
    • 0028174030 scopus 로고
    • NIH 3T3 cells stably transfected with the gene encoding phosphatidylcholine-hydrolyzing phospholipase C from Bacillus cereus acquire a transformed phenotype
    • Johansen, T., G. Bjorkoy, A. Overvatn, M. T. Diaz-Meco, T. Traavik, and J. Moscat. 1994. NIH 3T3 cells stably transfected with the gene encoding phosphatidylcholine-hydrolyzing phospholipase C from Bacillus cereus acquire a transformed phenotype. Mol. Cell. Biol. 14:646.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 646
    • Johansen, T.1    Bjorkoy, G.2    Overvatn, A.3    Diaz-Meco, M.T.4    Traavik, T.5    Moscat, J.6
  • 52
    • 0034864617 scopus 로고    scopus 로고
    • Cytokine-directed therapies for asthma
    • Barnes, P. J. 2001. Cytokine-directed therapies for asthma. J. Allergy Clin. Immunol. 108:S72.
    • (2001) J. Allergy Clin. Immunol. , vol.108
    • Barnes, P.J.1
  • 53
    • 0025975533 scopus 로고
    • Antiviral effects of xanthate D609 on the human respiratory syncytial virus growth cycle
    • Villanueva, N., J. Navarro, and E. Cubero. 1991. Antiviral effects of xanthate D609 on the human respiratory syncytial virus growth cycle. Virology 181:101.
    • (1991) Virology , vol.181 , pp. 101
    • Villanueva, N.1    Navarro, J.2    Cubero, E.3
  • 54
    • 0029812902 scopus 로고    scopus 로고
    • Function of the p55 tumor necrosis factor receptor "death domain" mediated by phosphatidylcholine-specific phospholipase C
    • Machleidt, T., B. Kramer, D. Adam, B. Neumann, S. Schutze, K. Wiegmann, and M. Kronke. 1996. Function of the p55 tumor necrosis factor receptor "death domain" mediated by phosphatidylcholine-specific phospholipase C. J. Exp. Med. 184:725.
    • (1996) J. Exp. Med. , vol.184 , pp. 725
    • Machleidt, T.1    Kramer, B.2    Adam, D.3    Neumann, B.4    Schutze, S.5    Wiegmann, K.6    Kronke, M.7


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