Anabolic effects of basic fibroblast growth factor in the tibial diaphysis of ovariectomized rats

Bone

Volumn 27, Issue 2, 2000, Pages 197-202

  Pun, S ^a   Florio, C L ^a   Wronski, T J ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Basic fibroblast growth factor; Bone formation; Bone histomorphometry; Cortical bone; Ovariectomy; Rat

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICAL BONE; DOSE RESPONSE; FEMALE; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OVARIECTOMY; RAT; TIBIA;

NON-PROGRAMMATIC;

ANIMALS; CALCIFICATION, PHYSIOLOGIC; CALCIUM; DIAPHYSES; FEMALE; FIBROBLAST GROWTH FACTOR 2; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; TIBIA; WEIGHT GAIN;

EID: 0033939597     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(00)00312-4     Document Type: Article

References (19)

1. Canalis E., Centrella M., McCarthy T. Effects of basic fibroblast growth factor on bone formation in vitro. J Clin Invest. 81:1988;1572-1577.
2. Dunstan C.R., Boyce R., Boyce B.F., Garrett I.R., Izbicka E., Burgess W.H., Mundy G.R. Systemic administration of acidic fibroblast growth factor (FGF-1) prevents bone loss and increases new bone formation in ovariectomized rats. J Bone Miner Res. 14:1999;953-959.
3. Globus R.K., Patterson-Buckendahl P., Gospodarowicz D. Regulation of bovine bone cell proliferation by fibroblast growth factor and transforming growth factor. Endocrinology. 123:1988;98-105.
4. Hanada K., Dennis J.E., Caplan A.I. Stimulatory effects of basic fibroblast growth factor and bone morphogenetic protein-2 on osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells. J Bone Miner Res. 12:1997;1606-1614.
5. Hesp R., Hulme P., Williams D., Reeve J. The relationship between changes in femoral bone density and calcium balance in patients with involutional osteoporosis treated with human parathyroid hormone fragment (hPTH 1-34). Metab Bone Dis. 2:1981;331-334.
6. Kalu D.N. The ovariectomized rat model of postmenopausal bone loss. Bone Miner. 15:1991;175-192.
7. Kawaguchi H., Kurokawa T., Hanada K., Hiyama Y., Tamura M., Ogata E., Matsumoto T. Stimulation of fracture repair by recombinant human basic fibroblast growth factor in normal and streptozotocin-diabetic rats. Endocrinology. 135:1994;774-781.
8. Liang H., Pun S., Wronski T.J. Bone anabolic effects of basic fibroblast growth factor in ovariectomized rats. Endocrinology. 140:1999;5780-5788.
9. Mayahara H., Ito T., Nagai H., Miyajima H., Tsukuda R., Taketomi S., Mizoguchi J., Kato K. In vivo stimulation of endosteal bone formation by basic fibroblast growth factor in rats. Growth Factors. 9:1993;73-80.
10. Nagai H., Tsukuda R., Mayahara H. Effects of basic fibroblast growth factor (bFGF) on bone formation in growing rats. Bone. 16:1995;367-373.
11. Nakamura T., Hanada K., Tamura M., Shibanushi T., Nigi H., Tagawa M., Fukumoto S., Matsumoto T. Stimulation of endosteal bone formation by systemic injections of recombinant basic fibroblast growth factor in rats. Endocrinology. 136:1995;1276-1284.
12. Nakamura K., Kurokawa T., Aoyama I., Hanada K., Tamura M., Kawaguchi H. Stimulation of bone formation by intraosseous injection of basic fibroblast growth factor in ovariectomised rats. Int Orthop. 22:1998;49-54.
13. Neer M., Slovik D.M., Daly M., Potts T. Jr, Nussbaum S.R. Treatment of postmenopausal osteoporosis with daily parathyroid hormone plus calcitriol. Osteoporosis Int. (Suppl. 1):1993;204-205.
14. Neter J., Wasserman W., Whitmore G.A. Applied Statistics. 1982;544-572 Allyn and Bacon, Boston.
15. Noff D., Pitaru S., Savion N. Basic fibroblast growth factor enhances the capacity of bone marrow cells to form bone-like nodules in vitro. FEBS Lett. 250:1989;619-621.
16. Pitaru S., Kotev-Emeth S., Noff D., Kaffuler S., Savion N. Effect of basic fibroblast growth factor on the growth and differentiation of adult stromal bone marrow cells enhanced development of mineralized bone-like tissue in culture. J Bone Miner Res. 8:1993;919-929.
17. Pri-Chen S., Pitaru S., Lokiec F., Savion N. Basic fibroblast growth factor enhances the growth and expression of the osteogenic phenotype of dexamethasone-treated human bone marrow-derived bone-like cells in culture. Bone. 23:1998;111-117.
18. Rodan S.B., Wesolowski G., Thomas K.A., Yoon K., Rodan G.A. Effects of acidic and basic fibroblast growth factors on osteoblastic cells. Connect Tissue Res. 20:1989;283-288.
19. Wronski T.J., Schenck P.A., Cintrón M., Walsh C.C. Effect of body weight on osteopenia in ovariectomized rats. Calcif Tissue Int. 40:1987;155-159.