Progressive alterations in global and GC-rich DNA methylation during tumorigenesis

Toxicological Sciences

Volumn 75, Issue 2, 2003, Pages 289-299

  Watson, Rebecca E ^a   Curtin, Geoffrey M ^b   Doolittle, David J ^b   Goodman, Jay I ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b R J REYNOLDS TOBACCO COMPANY   (United States)

Author keywords

DNA methylation; Epigenetics; Promotion; SENCAR mouse; Skin tumorigenesis; Tumorigenesis

Indexed keywords

CIGARETTE SMOKE CONDENSATE; DIMETHYLBENZ[A]ANTHRACENE; DNA; DNA METHYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CONTROLLED STUDY; DNA METHYLATION; DOSE RESPONSE; ENZYME ASSAY; FEMALE; GC RICH SEQUENCE; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; SKIN CARCINOGENESIS; TUMOR PROMOTION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; CYTOSINE; DNA METHYLATION; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; GUANOSINE; MICE; MICE, INBRED SENCAR; POLYMERASE CHAIN REACTION; RECOVERY OF FUNCTION; SKIN NEOPLASMS; SMOKE; TARS;

ANIMALIA;

EID: 0141841794     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg190     Document Type: Article

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