-
1
-
-
0043150152
-
-
Centers for Disease Control and Prevention and National Cancer Institute, Atlanta
-
US Cancer Statistics Working Group, Department of Health and Human Services United States Cancer Statistics: 1999 Incidence (Centers for Disease Control and Prevention and National Cancer Institute, Atlanta, 2002).
-
(2002)
United States Cancer Statistics: 1999 Incidence
-
-
-
2
-
-
0037260139
-
Cancer statistics, 2003
-
Jemal, A. et al. Cancer statistics, 2003. CA Cancer J. Clin. 53, 5-26 (2003).
-
(2003)
CA Cancer J. Clin.
, vol.53
, pp. 5-26
-
-
Jemal, A.1
-
3
-
-
0021739401
-
Second nonocular tumors in retinoblastoma survivors. Are they radiation-induced?
-
Abramson, D. H., Ellsworth, R. M., Kitchin, F. D. & Tung, G. Second nonocular tumors in retinoblastoma survivors. Are they radiation-induced? Ophthalmology 91, 1351-1355 (1984).
-
(1984)
Ophthalmology
, vol.91
, pp. 1351-1355
-
-
Abramson, D.H.1
Ellsworth, R.M.2
Kitchin, F.D.3
Tung, G.4
-
4
-
-
0030848527
-
Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk
-
Wong, F. L. et al. Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk. JAMA 278, 1262-1267 (1997).
-
(1997)
JAMA
, vol.278
, pp. 1262-1267
-
-
Wong, F.L.1
-
5
-
-
0014654544
-
Rhabdomyosarcoma in children: Epidemiologic study and identification of a familial cancer syndrome
-
Li, F. P. & Fraumeni, J. F. Jr. Rhabdomyosarcoma in children: epidemiologic study and identification of a familial cancer syndrome. J. Natl Cancer Inst. 43, 1365-1373 (1969).
-
(1969)
J. Natl. Cancer Inst.
, vol.43
, pp. 1365-1373
-
-
Li, F.P.1
Fraumeni J.F., Jr.2
-
6
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer sarcomas, and other neoplasms
-
Malkin, D. et al. Germ line p53 mutations in a familial syndrome of breast cancer sarcomas, and other neoplasms. Science 250, 1233-1238 (1990). First identification of germline mutations of TP53 in families with Li-Fraumeni syndrome.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
-
7
-
-
0034726722
-
Malignant peripheral nerve sheath tumors in neurofibromatosis 1
-
King, A. A., Debaun, M. R., Riccardi, V. M. & Gutmann, D. H. Malignant peripheral nerve sheath tumors in neurofibromatosis 1. J. Am. J. Med. Genet. 93, 388-392 (2000).
-
(2000)
J. Am. J. Med. Genet.
, vol.93
, pp. 388-392
-
-
King, A.A.1
Debaun, M.R.2
Riccardi, V.M.3
Gutmann, D.H.4
-
8
-
-
0031848146
-
Familial gastrointestinal stromal tumours with germline mutation of the KIT gene
-
Nishida, T. et al. Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nature Genet. 19, 323-324 (1998).
-
(1998)
Nature Genet.
, vol.19
, pp. 323-324
-
-
Nishida, T.1
-
9
-
-
0020595436
-
Angiosarcoma and hepatocellular carcinoma in vinyl chloride workers
-
Evans, D. M., Williams, W. J. & Kung, I. T. Angiosarcoma and hepatocellular carcinoma in vinyl chloride workers. Histopathology 7, 377-388 (1983).
-
(1983)
Histopathology
, vol.7
, pp. 377-388
-
-
Evans, D.M.1
Williams, W.J.2
Kung, I.T.3
-
10
-
-
0031045935
-
Angiosarcoma of the liver in Great Britain in proximity to vinyl chloride sites
-
Elliott, P. & Kleinschmidt, I. Angiosarcoma of the liver in Great Britain in proximity to vinyl chloride sites. Occup. Environ. Med. 54, 14-18 (1997).
-
(1997)
Occup. Environ. Med.
, vol.54
, pp. 14-18
-
-
Elliott, P.1
Kleinschmidt, I.2
-
11
-
-
0028277738
-
Postirradiation sarcomas. A single-institution study and review of the literature
-
Mark, R. J. et al. Postirradiation sarcomas. A single-institution study and review of the literature. Cancer 73, 2653-2662 (1994).
-
(1994)
Cancer
, vol.73
, pp. 2653-2662
-
-
Mark, R.J.1
-
12
-
-
0034960144
-
Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Mesothelloma
-
Sandberg, A. A. & Bridge, J. A. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: mesothelloma. Cancer Genet. Cytogenet. 127, 93-110 (2001).
-
(2001)
Cancer Genet. Cytogenet.
, vol.127
, pp. 93-110
-
-
Sandberg, A.A.1
Bridge, J.A.2
-
13
-
-
0036648376
-
Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Desmoplastic small round-cell tumors
-
Sandberg, A. A. & Bridge, J. A. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: desmoplastic small round-cell tumors. Cancer Genet. Cytogenet. 138, 1-10 (2002).
-
(2002)
Cancer Genet. Cytogenet.
, vol.138
, pp. 1-10
-
-
Sandberg, A.A.1
Bridge, J.A.2
-
14
-
-
0036648376
-
Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Alveolar soft part sarcoma
-
Sandberg, A. & Bridge, J. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: alveolar soft part sarcoma. Cancer Genet. Cytogenet. 138, 1-9 (2002).
-
(2002)
Cancer Genet. Cytogenet.
, vol.138
, pp. 1-9
-
-
Sandberg, A.1
Bridge, J.2
-
15
-
-
0036648376
-
A Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Gastrointestinal stromal tumors
-
Sandberg, A. A. & Bridge, J. A Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: gastrointestinal stromal tumors. Cancer Genet. Cytogenet. 135, 1-22 (2002).
-
(2002)
Cancer Genet. Cytogenet.
, vol.135
, pp. 1-22
-
-
Sandberg, A.A.1
Bridge, J.2
-
16
-
-
0036648376
-
Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Synovial sarcoma
-
Sandberg, A. A. & Bridge, J. A. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: synovial sarcoma. Cancer Genet. Cytogenet. 133, 1-23 (2002).
-
(2002)
Cancer Genet. Cytogenet.
, vol.133
, pp. 1-23
-
-
Sandberg, A.A.1
Bridge, J.A.2
-
17
-
-
0036165612
-
Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Congenital (infantile) fibrosarcoma and mesoblastic nephroma
-
Sandberg, A. A. & Bridge, J. A. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: congenital (infantile) fibrosarcoma and mesoblastic nephroma. Cancer Genet. Cytogenet. 132, 1-13 (2002).
-
(2002)
Cancer Genet. Cytogenet.
, vol.132
, pp. 1-13
-
-
Sandberg, A.A.1
Bridge, J.A.2
-
18
-
-
0037243434
-
Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Dermatofibrosarcoma protuberans and giant cell fibroblastoma
-
Sandberg, A. A. & Bridge, J. A. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: dermatofibrosarcoma protuberans and giant cell fibroblastoma. Cancer Genet. Cytogenet. 140, 1-12 (2003).
-
(2003)
Cancer Genet. Cytogenet.
, vol.140
, pp. 1-12
-
-
Sandberg, A.A.1
Bridge, J.A.2
-
19
-
-
0028881603
-
The PAX3-FKHR fusion protein created by the t(2; 13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3
-
Fredericks, W. J. et al. The PAX3-FKHR fusion protein created by the t(2; 13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3. Mol. Cell Biol. 15, 1522-1535 (1995).
-
(1995)
Mol. Cell Biol.
, vol.15
, pp. 1522-1535
-
-
Fredericks, W.J.1
-
20
-
-
0029980113
-
Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma
-
Bennicelli, J. L., Edwards, R. H. & Barr, F. G. Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma. Proc. Natl Acad. Sci. USA 93, 5455-5459 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5455-5459
-
-
Bennicelli, J.L.1
Edwards, R.H.2
Barr, F.G.3
-
21
-
-
0037414791
-
PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kp1, a potential role for elevated Skp2 expression
-
Zhang, L. & Wang, C. PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kp1, a potential role for elevated Skp2 expression. J. Biol. Chem. 278, 27-36 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27-36
-
-
Zhang, L.1
Wang, C.2
-
22
-
-
0036196163
-
Identification of target genes regulated by PAX3 and PAX3-FKHR in embryogenesis and alveolar rhabdomyosarcoma
-
Barber, T. D. et al. Identification of target genes regulated by PAX3 and PAX3-FKHR in embryogenesis and alveolar rhabdomyosarcoma. Genomics 79, 278-284 (2002).
-
(2002)
Genomics
, vol.79
, pp. 278-284
-
-
Barber, T.D.1
-
23
-
-
0032534066
-
Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays
-
Khan, J. et al. Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays. Cancer Res. 56, 5009-5013 (1998). Demonstration that a specific gene-expression profile can be associated with an alveolar rhabdomyosarcoma by microarray technology.
-
(1998)
Cancer Res.
, vol.56
, pp. 5009-5013
-
-
Khan, J.1
-
24
-
-
0034663196
-
Prognostic impact of p53 status in Ewing sarcoma
-
de Alava, E. et al. Prognostic impact of p53 status in Ewing sarcoma. Cancer 89, 783-792 (2000).
-
(2000)
Cancer
, vol.89
, pp. 783-792
-
-
De Alava, E.1
-
25
-
-
0034663338
-
Prognostic impact of INK4A deletion in Ewing sarcoma
-
Wei, G. et al. Prognostic impact of INK4A deletion in Ewing sarcoma. Cancer 89, 793-799 (2000).
-
(2000)
Cancer
, vol.89
, pp. 793-799
-
-
Wei, G.1
-
26
-
-
0031924824
-
EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma
-
de Alava, E. et al. EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma. J. Clin. Oncol. 16, 1248-1255 (1998).
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 1248-1255
-
-
De Alava, E.1
-
27
-
-
0036144655
-
Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: A multi-institutional retrospective study of 243 patients
-
Ladanyi, M. et al. Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients. Cancer Res. 62, 135-140 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 135-140
-
-
Ladanyi, M.1
-
28
-
-
0036605806
-
PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: A report from the children's oncology group
-
Sorensen, P. H. et al. PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group. J. Clin. Oncol. 20, 2672-2679 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 2672-2679
-
-
Sorensen, P.H.1
-
29
-
-
0033119006
-
Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma
-
Lin, P. P. et al. Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma. Cancer Res. 59, 1428-1432 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 1428-1432
-
-
Lin, P.P.1
-
30
-
-
0025178895
-
Mutation of the p53 gene in human soft tissue sarcomas: Association with abnormalities of the RB1 gene
-
Stratton, M. R. et al. Mutation of the p53 gene in human soft tissue sarcomas: association with abnormalities of the RB1 gene. Oncogene 5, 1297-1301 (1990).
-
(1990)
Oncogene
, vol.5
, pp. 1297-1301
-
-
Stratton, M.R.1
-
31
-
-
0029981711
-
Tumor suppressor genes and related molecules in leiomyosarcoma
-
Del Tos, A. P. et al. Tumor suppressor genes and related molecules in leiomyosarcoma. Am. J. Pathol. 148, 1037-1045 (1996).
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 1037-1045
-
-
Del Tos, A.P.1
-
32
-
-
0031780311
-
Mutation of the p53 gene in postradiation sarcoma
-
Nakanishi, H. et al. Mutation of the p53 gene in postradiation sarcoma. Lab. Invest. 78, 727-733 (1998).
-
(1998)
Lab. Invest.
, vol.78
, pp. 727-733
-
-
Nakanishi, H.1
-
33
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower, L. A. et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356, 215-221 (1992).
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
-
34
-
-
0027521657
-
Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice
-
Harvey, M. et al. Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice. Nature Genet. 5, 225-229 (1993).
-
(1993)
Nature Genet.
, vol.5
, pp. 225-229
-
-
Harvey, M.1
-
35
-
-
0033135110
-
Tumor spectrum in ARF-deficient mice
-
Kamijo, T., Bodner, S., van de Kamp, E., Randle, D. H. & Sherr, C. J. Tumor spectrum in ARF-deficient mice. Cancer Res. 59, 2217-2222 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 2217-2222
-
-
Kamijo, T.1
Bodner, S.2
Van de Kamp, E.3
Randle, D.H.4
Sherr, C.J.5
-
36
-
-
18244379848
-
Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions
-
Sharpless, N. E. et al. Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions. Mol. Cell 8, 1187-1196 (2001). Demonstration that mice that are prone to chromosomal abnormalities due to a defect in DNA repair become prone to the development of sarcomas.
-
(2001)
Mol. Cell
, vol.8
, pp. 1187-1196
-
-
Sharpless, N.E.1
-
37
-
-
0344097469
-
A case of dermatofibrosarcoma protuberans with a ring chromosome 5 and a rearranged chromosome 22 containing amplified COL1A1 and PDGFB sequences
-
Gisselsson, D. et al. A case of dermatofibrosarcoma protuberans with a ring chromosome 5 and a rearranged chromosome 22 containing amplified COL1A1 and PDGFB sequences. Cancer Lett. 133, 129-134 (1998).
-
(1998)
Cancer Lett.
, vol.133
, pp. 129-134
-
-
Gisselsson, D.1
-
38
-
-
0031012850
-
Deregulation of the platelet-derived growth factor B-chain gene via fusion with collagen gene COL1A1 in dermatofibrosarcoma protuberans and giant-cell fibroblastoma
-
Simon, M. P. et al. Deregulation of the platelet-derived growth factor B-chain gene via fusion with collagen gene COL1A1 in dermatofibrosarcoma protuberans and giant-cell fibroblastoma. Nature Genet. 15, 95-98 (1997). Demonstration of activation of PDGFB in dermatofibrosarcoma protuberans through a translocation and fusion with the COL1A1 gene.
-
(1997)
Nature Genet.
, vol.15
, pp. 95-98
-
-
Simon, M.P.1
-
39
-
-
0031661840
-
Various regions within the alpha-helical domain of the COL1A1 gene are fused to the second exon of the PDGFB gene in dermatofibrosarcomas and giant-cell fibroblastomas
-
O'Brien, K. P. et al. Various regions within the alpha-helical domain of the COL1A1 gene are fused to the second exon of the PDGFB gene in dermatofibrosarcomas and giant-cell fibroblastomas. Genes Chromosom. Cancer 23, 187-193 (1998).
-
(1998)
Genes Chromosom. Cancer
, vol.23
, pp. 187-193
-
-
O'Brien, K.P.1
-
40
-
-
0033178762
-
The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB
-
Shimizu, A. et al. The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB. Cancer Res. 59, 3719-3723 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 3719-3723
-
-
Shimizu, A.1
-
41
-
-
0036727124
-
Molecular targeting of platelet-derived growth factor B by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans
-
Rubin, B. P. et al. Molecular targeting of platelet-derived growth factor B by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans. J. Clin. Oncol. 20, 3586-3591 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 3586-3591
-
-
Rubin, B.P.1
-
42
-
-
18344391009
-
Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21
-
Meza-Zepeda, L. A. et al. Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21. Oncogene 21, 2261-2269 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 2261-2269
-
-
Meza-Zepeda, L.A.1
-
43
-
-
17344371740
-
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
-
Pinkel, D. et al. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nature Genet. 20, 207-211 (1998). By using genomic clones in a microarray format, it was possible to obtain superior resolution in comparative genomic hybridization.
-
(1998)
Nature Genet.
, vol.20
, pp. 207-211
-
-
Pinkel, D.1
-
44
-
-
0036606764
-
Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma
-
Fritz, B. et al. Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma. Cancer Res. 62, 2993-2998 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 2993-2998
-
-
Fritz, B.1
-
45
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell 81, 323-330 (1995).
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
46
-
-
0030824829
-
Loss of RB and MTS1/CDKN2 (p16) expression in human sarcomas
-
Cohen, J. A. & Geradts, J. Loss of RB and MTS1/CDKN2 (p16) expression in human sarcomas. Hum. Pathol. 28, 893-898 (1997).
-
(1997)
Hum. Pathol.
, vol.28
, pp. 893-898
-
-
Cohen, J.A.1
Geradts, J.2
-
47
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell 88, 323-331 (1997).
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
48
-
-
0032192140
-
The complexity of p53 modulation: Emerging patterns from divergent signals
-
Giaccia, A. J. & Kastan, M. B. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12, 2973-2983 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 2973-2983
-
-
Giaccia, A.J.1
Kastan, M.B.2
-
49
-
-
0035227097
-
Aberrant expression of cell-cycle regulatory proteins in human mesenchymal neoplasia
-
Creager, A. J., Cohen, J. A. & Geradts, J. Aberrant expression of cell-cycle regulatory proteins in human mesenchymal neoplasia. Cancer Detect. Prev. 26, 123-131 (2001).
-
(2001)
Cancer Detect. Prev.
, vol.26
, pp. 123-131
-
-
Creager, A.J.1
Cohen, J.A.2
Geradts, J.3
-
50
-
-
0027232042
-
p53 mutation and MDM2 amplification in human soft tissue sarcomas
-
Leach, F. S. et al. p53 Mutation and MDM2 amplification in human soft tissue sarcomas. Cancer Res. 53, 2231-2234 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 2231-2234
-
-
Leach, F.S.1
-
51
-
-
0024006721
-
Expression of insulin-like growth factor-I and-II genes in human smooth muscle tumours
-
Hoppener, J. W. et al. Expression of insulin-like growth factor-I and-II genes in human smooth muscle tumours. EMBO J. 7, 1379-1385 (1988).
-
(1988)
EMBO J.
, vol.7
, pp. 1379-1385
-
-
Hoppener, J.W.1
-
52
-
-
0025323554
-
Expression of insulin-like growth factor 1 in sarcomas
-
Roholl, P. J. et al. Expression of insulin-like growth factor 1 in sarcomas. Histopathology 16, 455-460 (1990).
-
(1990)
Histopathology
, vol.16
, pp. 455-460
-
-
Roholl, P.J.1
-
53
-
-
0036789557
-
Reduced growth of human sarcoma xenografts in hosts homozygous for the lit mutation
-
Deitel, K. et al. Reduced growth of human sarcoma xenografts in hosts homozygous for the lit mutation. J. Surg. Oncol. 81, 75-79 (2002).
-
(2002)
J. Surg. Oncol.
, vol.81
, pp. 75-79
-
-
Deitel, K.1
-
54
-
-
0032513524
-
Expression of a kinase-deficient IGF-I-R suppresses tumorigenicity of rhabdomyosarcoma cells constitutively expressing a wild type IGF-I-R
-
Kalebic, T. et al. Expression of a kinase-deficient IGF-I-R suppresses tumorigenicity of rhabdomyosarcoma cells constitutively expressing a wild type IGF-I-R. Int. J. Cancer 76, 223-227 (1998).
-
(1998)
Int. J. Cancer
, vol.76
, pp. 223-227
-
-
Kalebic, T.1
-
55
-
-
0036847703
-
Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571
-
McGary, E. C. et al. Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571. Clin. Cancer Res. 8, 3584-3591 (2002).
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3584-3591
-
-
McGary, E.C.1
-
56
-
-
0030699247
-
The EWS-WT1 translocation product induces PDGFA in desmoplastic small round-cell tumour
-
Lee, S. B. et al. The EWS-WT1 translocation product induces PDGFA in desmoplastic small round-cell tumour. Nature Genet. 17, 309-313 (1997).
-
(1997)
Nature Genet.
, vol.17
, pp. 309-313
-
-
Lee, S.B.1
-
57
-
-
0037146220
-
Potential use of imatinib in Ewing's Sarcoma: Evidence for in vitro and in vivo activity
-
Merchant, M. S., Woo, C. W., Mackall, C. L. & Thiele, C. J. Potential use of imatinib in Ewing's Sarcoma: evidence for in vitro and in vivo activity. J. Natl Cancer Inst. 94, 1673-1679 (2002).
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 1673-1679
-
-
Merchant, M.S.1
Woo, C.W.2
Mackall, C.L.3
Thiele, C.J.4
-
58
-
-
0036319991
-
Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution
-
Hornick, J. L. & Fletcher, C. D. Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution. Am. J. Clin. Pathol. 117, 158-193 (2002).
-
(2002)
Am. J. Clin. Pathol.
, vol.117
, pp. 158-193
-
-
Hornick, J.L.1
Fletcher, C.D.2
-
59
-
-
0034956005
-
Gastrointestinal stromal tumor workshop
-
Berman, J. & O'Leary, T. J. Gastrointestinal stromal tumor workshop. Hum. Pathol. 32, 578-582 (2001).
-
(2001)
Hum. Pathol.
, vol.32
, pp. 578-582
-
-
Berman, J.1
O'Leary, T.J.2
-
60
-
-
0035890740
-
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors
-
Rubin, B. P. et al. KIT activation is a ubiquitous feature of gastrointestinal stromal tumors. Cancer Res. 61, 8118-8121 (2001). Shows activation of KIT in the majority of GISTs.
-
(2001)
Cancer Res.
, vol.61
, pp. 8118-8121
-
-
Rubin, B.P.1
-
61
-
-
0033901252
-
Overexpression of the hepatocyte growth factor (HGF) receptor (Met) and presence of a truncated and activated intracellular HGF receptor fragment in locally aggressive/malignant human musculoskeletal tumors
-
Wallenius, V. et al. Overexpression of the hepatocyte growth factor (HGF) receptor (Met) and presence of a truncated and activated intracellular HGF receptor fragment in locally aggressive/malignant human musculoskeletal tumors. Am. J. Pathol. 156, 821-829 (2000).
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 821-829
-
-
Wallenius, V.1
-
62
-
-
0035800513
-
c-KIT and c-KIT ligand (SCF) in synovial sarcoma (SS): An mRNA expression analysis in 23 cases
-
Tamborini, E. et al. c-KIT and c-KIT ligand (SCF) in synovial sarcoma (SS): an mRNA expression analysis in 23 cases. Br. J. Cancer 85, 405-411 (2001).
-
(2001)
Br. J. Cancer
, vol.85
, pp. 405-411
-
-
Tamborini, E.1
-
63
-
-
0033966745
-
Expression of hepatocyte growth factor (HGF)/scatter factor and its receptor c-MET correlates with poor prognosis in synovial sarcoma
-
Oda, Y. et al. Expression of hepatocyte growth factor (HGF)/scatter factor and its receptor c-MET correlates with poor prognosis in synovial sarcoma. Hum. Pathol. 31, 185-192 (2000).
-
(2000)
Hum. Pathol.
, vol.31
, pp. 185-192
-
-
Oda, Y.1
-
64
-
-
0011701480
-
Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas
-
Ferracini, R. et al. Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas. Oncogene 12, 1697-1705 (1996).
-
(1996)
Oncogene
, vol.12
, pp. 1697-1705
-
-
Ferracini, R.1
-
65
-
-
0025461112
-
Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors
-
El-Badry, O. M. et al. Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors. Cell Growth Differ. 1, 325-331 (1990).
-
(1990)
Cell Growth Differ.
, vol.1
, pp. 325-331
-
-
El-Badry, O.M.1
-
66
-
-
0028115727
-
Specific expression of insulin-like growth factor-II in rhabdomyosarcoma tumor cells
-
Minniti, C. P., Tsokos, M., Newton, W. A. Jr. & Helman, L. J. Specific expression of insulin-like growth factor-II in rhabdomyosarcoma tumor cells. Am. J. Clin. Pathol. 101, 198-203 (1994).
-
(1994)
Am. J. Clin. Pathol.
, vol.101
, pp. 198-203
-
-
Minniti, C.P.1
Tsokos, M.2
Newton W.A., Jr.3
Helman, L.J.4
-
67
-
-
85117738070
-
Leukemia in twins: Lessons in natural history
-
in the press
-
Greaves, M., Maia, A. T., Wiemels, J. L. & Ford, A. M. Leukemia in twins: lessons in natural history. Blood (in the press).
-
Blood
-
-
Greaves, M.1
Maia, A.T.2
Wiemels, J.L.3
Ford, A.M.4
-
68
-
-
0032189704
-
Insulin-like growth factor II and PAX3-FKHR cooperate in the oncogenesis of rhabdomyosarcoma
-
Wang, W. et al. Insulin-like growth factor II and PAX3-FKHR cooperate in the oncogenesis of rhabdomyosarcoma. Cancer Res. 56, 4426-4433 (1998).
-
(1998)
Cancer Res.
, vol.56
, pp. 4426-4433
-
-
Wang, W.1
-
69
-
-
0032533497
-
ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma
-
Knezevich, S. R. et al. ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma. Cancer Res. 56, 5046-5048 (1998). Identification of the identical genetic alteration of mesoblastic nephroma and congenital fibrosarcoma, linking these two tumours as genetically identical.
-
(1998)
Cancer Res.
, vol.56
, pp. 5046-5048
-
-
Knezevich, S.R.1
-
70
-
-
0035893766
-
Gastrointestinal stromal tumors with KIT mutations exhibit a remarkably homogeneous gene expression profile
-
Allander, S. V. et al. Gastrointestinal stromal tumors with KIT mutations exhibit a remarkably homogeneous gene expression profile. Cancer Res. 61, 8624-8648 (2001).
-
(2001)
Cancer Res.
, vol.61
, pp. 8624-8648
-
-
Allander, S.V.1
-
71
-
-
0036840271
-
Expression profiling of synovial sarcoma by cDNA microarrays: Association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation
-
Allander, S. V. et al. Expression profiling of synovial sarcoma by cDNA microarrays: association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation. Am. J. Pathol. 161, 1587-1595 (2002).
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 1587-1595
-
-
Allander, S.V.1
-
72
-
-
0033539498
-
cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene
-
Khan, J. et al. cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene. Proc. Natl Acad. Sci. USA 96, 13264-13269 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13264-13269
-
-
Khan, J.1
-
73
-
-
0037109028
-
Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray
-
Nagayama, S. et al. Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray. Cancer Res. 62, 5859-5866 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 5859-5866
-
-
Nagayama, S.1
-
74
-
-
0345074093
-
Studies on the molecular pathogenesis of extraskeletal myxoid chondrosarcoma-cytogenetic, molecular genetic, and cDNA microarray analyses
-
Sjogren, H. et al. Studies on the molecular pathogenesis of extraskeletal myxoid chondrosarcoma-cytogenetic, molecular genetic, and cDNA microarray analyses. Am. J. Pathol. 162, 781-792 (2003).
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 781-792
-
-
Sjogren, H.1
-
75
-
-
0037070754
-
Molecular characterisation of soft tissue tumours: A gene expression study
-
Nielsen, T. O. et al. Molecular characterisation of soft tissue tumours: a gene expression study. Lancet 359, 1301-1307 (2002).
-
(2002)
Lancet
, vol.359
, pp. 1301-1307
-
-
Nielsen, T.O.1
-
76
-
-
0036560740
-
The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts
-
Lessnick, S. L., Dacwag, C. S. & Golub, T. R. The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts. Cancer Cell 1, 393-401 (2002).
-
(2002)
Cancer Cell
, vol.1
, pp. 393-401
-
-
Lessnick, S.L.1
Dacwag, C.S.2
Golub, T.R.3
-
77
-
-
0037569709
-
PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins
-
Deneen, B. et al. PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins. Mol. Cell. Biol. 23, 3897-3908 (2003).
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3897-3908
-
-
Deneen, B.1
-
78
-
-
23444443039
-
CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest
-
Barone, M. V., Crozat, A., Tabaee, A., Philipson, L. & Ron, D. CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. Genes Dev. 8, 453-464 (1994).
-
(1994)
Genes Dev.
, vol.8
, pp. 453-464
-
-
Barone, M.V.1
Crozat, A.2
Tabaee, A.3
Philipson, L.4
Ron, D.5
-
79
-
-
0032546811
-
Human translocation liposarcoma-CCAAT/enhancer binding protein (C/EBP) homologous protein (TLS-CHOP) oncoprotein prevents adipocyte differentiation by directly interfering with C/EBPbeta function
-
Adelmant, G., Gilbert, J. D. & Freytag, S. O. Human translocation liposarcoma-CCAAT/enhancer binding protein (C/EBP) homologous protein (TLS-CHOP) oncoprotein prevents adipocyte differentiation by directly interfering with C/EBPbeta function. J. Biol. Chem. 273, 15574-15581 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15574-15581
-
-
Adelmant, G.1
Gilbert, J.D.2
Freytag, S.O.3
-
80
-
-
0036319256
-
RNA splicing mediated by YB-1 is inhibited by TLS/CHOP in human myxoid liposarcoma cells
-
Rapp, T. B., Yang, L., Conrad, E. U., Mandahl, N. & Chansky, H. A. RNA splicing mediated by YB-1 is inhibited by TLS/CHOP in human myxoid liposarcoma cells. J. Orthop. Res. 20, 723-729 (2002).
-
(2002)
J. Orthop. Res.
, vol.20
, pp. 723-729
-
-
Rapp, T.B.1
Yang, L.2
Conrad, E.U.3
Mandahl, N.4
Chansky, H.A.5
-
81
-
-
0035933847
-
EWS/FLI alters 5′-splice site selection
-
Knoop, L. L. & Baker, S. J. EWS/FLI alters 5′-splice site selection. J. Biol. Chem. 276, 22317-22322 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22317-22322
-
-
Knoop, L.L.1
Baker, S.J.2
-
82
-
-
0034637482
-
The splicing factor U1C represses EWS/FLI-mediated transactivation
-
Knoop, L. L. & Baker, S. J. The splicing factor U1C represses EWS/FLI-mediated transactivation. J. Biol. Chem. 275, 24865-24871 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24865-24871
-
-
Knoop, L.L.1
Baker, S.J.2
-
83
-
-
0034619768
-
Liposarcoma initiated by FUS/TLS-CHOP: The FUS/TLS domain plays a critical role in the pathogenesis of liposarcoma
-
Perez-Losada, J. et al. Liposarcoma initiated by FUS/TLS-CHOP: the FUS/TLS domain plays a critical role in the pathogenesis of liposarcoma. Oncogene 19, 6015-6022 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 6015-6022
-
-
Perez-Losada, J.1
-
84
-
-
85047700041
-
Expression of the FUS domain restores liposarcoma development in CHOP transgenic mice
-
Perez-Mancera, P. A. et al. Expression of the FUS domain restores liposarcoma development in CHOP transgenic mice. Oncogene 21, 1679-1684 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 1679-1684
-
-
Perez-Mancera, P.A.1
-
85
-
-
0036787919
-
Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors
-
Lagutina, I., Conway, S. J., Sublett, J. & Grosveld, G. C. Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors. Mol. Cell. Biol. 22, 7204-7216 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7204-7216
-
-
Lagutina, I.1
Conway, S.J.2
Sublett, J.3
Grosveld, G.C.4
-
86
-
-
0009615132
-
A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting
-
Scrable, H. et al. A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting. Proc. Natl Acad. Sci. USA 86, 7480-7484 (1989).
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7480-7484
-
-
Scrable, H.1
-
87
-
-
0034665975
-
Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma
-
Hahn, H. et al. Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma. J. Biol. Chem. 275, 28341-28344 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28341-28344
-
-
Hahn, H.1
-
88
-
-
0033588883
-
Rhabdomyosarcoma - Working out the pathways
-
Merlino, G. & Helman, L. J. Rhabdomyosarcoma - working out the pathways. Oncogene 18, 5340-5348 (1999).
-
(1999)
Oncogene
, vol.18
, pp. 5340-5348
-
-
Merlino, G.1
Helman, L.J.2
-
89
-
-
0036851869
-
Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis
-
Sharp, R. et al. Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis. Nature Med. 8, 1276-1280 (2002). Construction of a genetic model of rhabdomyosarcoma with nearly complete penetrance.
-
(2002)
Nature Med.
, vol.8
, pp. 1276-1280
-
-
Sharp, R.1
-
90
-
-
0035960428
-
Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: A phase I study
-
van Oosterom, A. T. et al. Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study. Lancet 358, 1421-1423 (2001). First large clinical trial showing the remarkable effectiveness of imatinib in GISTs.
-
(2001)
Lancet
, vol.358
, pp. 1421-1423
-
-
Van Oosterom, A.T.1
-
91
-
-
0242670019
-
PDGFRA activating mutations in gastrointestinal stromal tumors
-
Heinrich, M. C. et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science 299, 708-710 (2003).
-
(2003)
Science
, vol.299
, pp. 708-710
-
-
Heinrich, M.C.1
-
92
-
-
0037392444
-
Issues and progress with protein kinase inhibitors for cancer treatment
-
Dancey, J. & Sausville, E. A. Issues and progress with protein kinase inhibitors for cancer treatment. Nature Rev. Drug Discov. 2, 296-313 (2003).
-
(2003)
Nature Rev. Drug Discov.
, vol.2
, pp. 296-313
-
-
Dancey, J.1
Sausville, E.A.2
-
93
-
-
0033987746
-
Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
-
Druker, B. J. & Lydon, N. B. Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia. J. Clin. Invest. 105, 3-7 (2000).
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 3-7
-
-
Druker, B.J.1
Lydon, N.B.2
|