Involvement of the retinoblastoma (pRb) - E2F/DP pathway during antiproliferative effects of resveratrol in human epidermoid carcinoma (A431) cells

Biochemical and Biophysical Research Communications

Volumn 288, Issue 3, 2001, Pages 579-585

  Adhami, Vaqar M ^a   Afaq, Farrukh ^a   Ahmad, Nihal ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cell cycle; E2F; Resveratrol; Retinoblastoma

Indexed keywords

CYCLIN D1; CYCLIN D2; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; PROTEIN P21; RESVERATROL; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE PHASE; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SQUAMOUS CELL CARCINOMA;

VITACEAE;

EID: 0035798154     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5819     Document Type: Article

References (49)

1. Green tea polyphenols and cancer: Biologic mechanisms and practical implications
2. Recent advances in chemoprevention of cancer
3. Progress in cancer chemoprevention: Development of diet-derived chemopreventive agents
4. Chemoprevention of cancer
5. Cancer chemoprevention: Future holds in multiple agents
6. The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury
7. Resveratrol, melatonin, vitamin E, and PBN protect against renal oxidative DNA damage induced by the kidney carcinogen KBrO3
8. Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production
9. Cardioprotection of red wine: Role of polyphenolic antioxidants
10. Wine, alcohol, platelets, and the French paradox for coronary heart disease
11. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
12. Cancer chemopreventive activity of resveratrol
13. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
14. A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol
15. 2 phases of the cell cycle in U937 cells
16. Resveratrol, a natural product present in wine, decreases tumour growth in a rat tumor model
17. Effects of resveratrol on 12-O-tetradecanoylphorbol-13-acetate-induced oxidative events and gene expression in mouse skin
18. Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase
19. Grape-derived chemopreventive agent resveratrol decreases prostate-specific antigen (PSA) expression in LNCaP cells by an androgen receptor (AR)-independent mechanism
20. Resveratrol selectively inhibits leukemia cells: A prospective agent for ex vivo bone marrow purging
21. Resveratrol inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells
22. Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells
23. Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials
24. Differential effects on growth, cell cycle arrest, and induction of apoptosis by resveratrol in human prostate cancer cell lines
25. 2
26. Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21(CIP) expression
27. Resveratrol inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells
28. 1-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells
29. Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells
30. The cell cycle and cancer
31. Cancer cell cycles
32. Cell cycle molecular targets in novel anticancer drug discovery
33. Synthetic cyclin dependent kinase inhibitors. New generation of potent anti-cancer drugs
34. Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances
35. Role of the PRb/E2F pathway in cell growth control
36. Functions of the retinoblastoma protein
37. Rb function in cell-cycle regulation and apoptosis
38. The retinoblastoma protein and cell cycle control
39. The Rb family of cell cycle regulatory factors: Clinical implications
40. DP and E2F proteins: Coordinating transcription with cell cycle progression
41. E2F and cell proliferation: A world turned upside down
42. Regulation of E2F transcription by cyclinE - cdk2 kinase mediated through p300/CBP co-activators
43. Mechanism of active transcriptional repression by the retinoblastoma protein
44. RB kinases and RB-binding proteins: New points of view
45. pRb and the cdks in apoptosis and the cell cycle
46. Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis
47. Involvement of retinoblastoma (Rb) and E2F transcription factors during photodynamic therapy of human epidermoid carcinoma cells A431
48. 1 restriction point fails to halt cell cycle progression
49. Radiation-induced apoptosis mediated by retinoblastoma protein