-
1
-
-
0035861684
-
Down-regulation of integrin αvβ3 expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense urokinase-type plasminogen activator receptor (uPA-R) and sense p16 genes
-
Adachi, Y., Lakka, S. S., Chandrasekar, N., Yanamandra, N., Gondi, C. S., Mohanam, S., Dinh, D. H., Olivero, W. C., Gujrati, M., Tamiya, T. et al. (2001). Down-regulation of integrin αvβ3 expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense urokinase-type plasminogen activator receptor (uPA-R) and sense p16 genes. J. Biol. Chem. 276, 47171-47177.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47171-47177
-
-
Adachi, Y.1
Lakka, S.S.2
Chandrasekar, N.3
Yanamandra, N.4
Gondi, C.S.5
Mohanam, S.6
Dinh, D.H.7
Olivero, W.C.8
Gujrati, M.9
Tamiya, T.10
-
2
-
-
0036123185
-
Overexpression of αvβ6 integrin in serous epithelial ovarian cancer regulates extracellular matrix degradation via the plasminogen activation cascade
-
Ahmed, N., Pansino, F., Clyde, R., Murthi, P., Quinn, M. A., Rice, G. E., Agrez, M. V., Mok, S., and Baker, M. S. (2002). Overexpression of αvβ6 integrin in serous epithelial ovarian cancer regulates extracellular matrix degradation via the plasminogen activation cascade. Carcinogenesis 23, 237-244.
-
(2002)
Carcinogenesis
, vol.23
, pp. 237-244
-
-
Ahmed, N.1
Pansino, F.2
Clyde, R.3
Murthi, P.4
Quinn, M.A.5
Rice, G.E.6
Agrez, M.V.7
Mok, S.8
Baker, M.S.9
-
3
-
-
0038405134
-
Induction of apoptosis in vascular cells by plasminogen activator inhibitor-1 and high molecular weight kininogen correlates with their anti-adhesive properties
-
Al-Fakhri, N., Chavakis, T., Schmidt-Wöll, T., Huang, B., Cherian, S. M., Bobryshev, Y. V., Lord, R. S. A., Katz, N., and Preissner, K. T. (2003). Induction of apoptosis in vascular cells by plasminogen activator inhibitor-1 and high molecular weight kininogen correlates with their anti-adhesive properties. Biol. Chem. 384, 423-435.
-
(2003)
Biol. Chem.
, vol.384
, pp. 423-435
-
-
Al-Fakhri, N.1
Chavakis, T.2
Schmidt-Wöll, T.3
Huang, B.4
Cherian, S.M.5
Bobryshev, Y.V.6
Lord, R.S.A.7
Katz, N.8
Preissner, K.T.9
-
4
-
-
0033981473
-
The plasminogen activation system in tumor growth, invasion, and metastasis
-
Andreasen, P. A., Egelund, R., and Petersen, H. H. (2000). The plasminogen activation system in tumor growth, invasion, and metastasis. Cell. Mol. Life Sci. 57, 25-40.
-
(2000)
Cell. Mol. Life Sci.
, vol.57
, pp. 25-40
-
-
Andreasen, P.A.1
Egelund, R.2
Petersen, H.H.3
-
5
-
-
0036156207
-
Interaction of plasminogen activator inhibitor type-1 (PAI-1) with vitronectin
-
Arroyo De Prada, N., Schroeck, F., Sinner, E. K., Muehlenweg, B., Twellmeyer, J., Sperl, S., Wilhelm, O. G., Schmitt, M., and Magdolen, V. (2002). Interaction of plasminogen activator inhibitor type-1 (PAI-1) with vitronectin. Eur. J. Biochem. 269, 184-192.
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 184-192
-
-
Arroyo De Prada, N.1
Schroeck, F.2
Sinner, E.K.3
Muehlenweg, B.4
Twellmeyer, J.5
Sperl, S.6
Wilhelm, O.G.7
Schmitt, M.8
Magdolen, V.9
-
6
-
-
0031902286
-
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization
-
Bajou, K., Noel, A., Gerard, R. D., Masson, V., Brunner, N., Holst-Hansen, C., Skobe, M., Fusenig, N. E., Carmeliet, P., Collen, D., and Foidart, J. M. (1998). Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nature Med. 4, 923-928.
-
(1998)
Nature Med.
, vol.4
, pp. 923-928
-
-
Bajou, K.1
Noel, A.2
Gerard, R.D.3
Masson, V.4
Brunner, N.5
Holst-Hansen, C.6
Skobe, M.7
Fusenig, N.E.8
Carmeliet, P.9
Collen, D.10
Foidart, J.M.11
-
7
-
-
0035911151
-
The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for anti-angiogenic strategies
-
Bajou, K., Masson, V., Gerard, R. D., Schmitt, P. M., Albert, V., Praus, M., Lund, L. R., Frandsen, T. L., Brunner, N., Danø, K. et al. (2001). The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for anti-angiogenic strategies. J. Cell Biol. 152, 777-784.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 777-784
-
-
Bajou, K.1
Masson, V.2
Gerard, R.D.3
Schmitt, P.M.4
Albert, V.5
Praus, M.6
Lund, L.R.7
Frandsen, T.L.8
Brunner, N.9
Danø, K.10
-
8
-
-
0036981443
-
Role of PAI-1 plasminogen activator inhibitor in tumor invasion and angiogenesis
-
Bajou, K. (2002). Role of PAI-1 plasminogen activator inhibitor in tumor invasion and angiogenesis. Bull. Mem. Acad. R. Med. Belg. 157, 313-318.
-
(2002)
Bull. Mem. Acad. R. Med. Belg.
, vol.157
, pp. 313-318
-
-
Bajou, K.1
-
9
-
-
0032562080
-
Fibronectin binding promotes a PKC-dependent modulation of NF-kappa B in human T cells
-
Bearz, A., Tell, G., Colombatti, A., Formisano, S., and Pucillo, C. (1998). Fibronectin binding promotes a PKC-dependent modulation of NF-kappa B in human T cells. Biochem. Biophys. Res. Commun. 243, 732-737.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.243
, pp. 732-737
-
-
Bearz, A.1
Tell, G.2
Colombatti, A.3
Formisano, S.4
Pucillo, C.5
-
10
-
-
0037107601
-
Role of β3-endonexin in the regulation of NF-κB-dependent expression of urokinase-type plasminogen activator receptor
-
Besta, F., Massberg, S., Brand, K., Muller, E., Page, S., Gruner, S., Lorenz, M., Sadoul, K., Kolanus, W., Lengyel, E., and Gawaz, M. (2002). Role of β3-endonexin in the regulation of NF-κB-dependent expression of urokinase-type plasminogen activator receptor. J. Cell Sci. 115, 3879-3888.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 3879-3888
-
-
Besta, F.1
Massberg, S.2
Brand, K.3
Muller, E.4
Page, S.5
Gruner, S.6
Lorenz, M.7
Sadoul, K.8
Kolanus, W.9
Lengyel, E.10
Gawaz, M.11
-
12
-
-
0028925552
-
Urokinase plasminogen activator receptor, β2-integrin, and src-kinases within a single receptor complex of human monocytes
-
Bohuslav, J., Horejsi, V., Hansmann, C., Stöckl, J., Weidle, U. H., Majdic, O., Bartke, I., Knapp, W., and Stockinger, H. (1995). Urokinase plasminogen activator receptor, β2-integrin, and src-kinases within a single receptor complex of human monocytes. J. Exp. Med. 181, 1381-1390.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1381-1390
-
-
Bohuslav, J.1
Horejsi, V.2
Hansmann, C.3
Stöckl, J.4
Weidle, U.H.5
Majdic, O.6
Bartke, I.7
Knapp, W.8
Stockinger, H.9
-
13
-
-
0032698213
-
Urokinase receptor interacts with αvβ5 vitronectin receptor, promoting urokinase-dependent cell migration in breast cancer
-
Carriero, M. V., Del Vecchio, S., Capozzoli, M., Franco, P., Fontana, L., Zannetti, A., Botti, G., D'Aiuto, G., Salvatore, M., and Stoppelli, M. P. (1999). Urokinase receptor interacts with αvβ5 vitronectin receptor, promoting urokinase-dependent cell migration in breast cancer. Cancer Res. 59, 5307-5314.
-
(1999)
Cancer Res.
, vol.59
, pp. 5307-5314
-
-
Carriero, M.V.1
Del Vecchio, S.2
Capozzoli, M.3
Franco, P.4
Fontana, L.5
Zannetti, A.6
Botti, G.7
D'Aiuto, G.8
Salvatore, M.9
Stoppelli, M.P.10
-
14
-
-
0031700046
-
Urokinase receptor-dependent upregulation of smooth muscle cell adhesion to vitronectin by urokinase
-
Chang, A. W., Kuo, A., Barnathan, E. S., and Okada, S. (1998). Urokinase receptor-dependent upregulation of smooth muscle cell adhesion to vitronectin by urokinase. Arterioscler. Thromb. Vasc. Biol. 18, 1855-1860.
-
(1998)
Arterioscler. Thromb. Vasc. Biol.
, vol.18
, pp. 1855-1860
-
-
Chang, A.W.1
Kuo, A.2
Barnathan, E.S.3
Okada, S.4
-
15
-
-
0034923326
-
Protease crosstalk with integrins: The urokinase receptor paradigm
-
Chapman, H. A. and Wei, Y (2001). Protease crosstalk with integrins: the urokinase receptor paradigm. Thromb. Haemost. 86, 124-129.
-
(2001)
Thromb. Haemost.
, vol.86
, pp. 124-129
-
-
Chapman, H.A.1
Wei, Y.2
-
16
-
-
0032695915
-
Role of urokinase receptor and caveolin in regulation of integrin signaling
-
Chapman, H. A., Wei, Y., Simon, D. I., and Waltz, D. A. (1999). Role of urokinase receptor and caveolin in regulation of integrin signaling. Thromb. Haemost. 82, 291-297.
-
(1999)
Thromb. Haemost.
, vol.82
, pp. 291-297
-
-
Chapman, H.A.1
Wei, Y.2
Simon, D.I.3
Waltz, D.A.4
-
17
-
-
0036549938
-
Haemostatic factors occupy new territory: The role of the urokinase receptor system and kininogen in inflammation
-
Chavakis, T., Kanse, S. M., May, A. E., and Preissner, K. T. (2002). Haemostatic factors occupy new territory: the role of the urokinase receptor system and kininogen in inflammation. Biochem. Soc. Trans. 30, 168-173.
-
(2002)
Biochem. Soc. Trans.
, vol.30
, pp. 168-173
-
-
Chavakis, T.1
Kanse, S.M.2
May, A.E.3
Preissner, K.T.4
-
18
-
-
0026680818
-
Vitronectin regulates the synthesis and localization of urokinase-type plasminogen activator in HT-1080 cells
-
Ciambrone, G. J. and McKeown-Longo, P. J. (1992). Vitronectin regulates the synthesis and localization of urokinase-type plasminogen activator in HT-1080 cells. J. Biol. Chem. 267, 13617-13622.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 13617-13622
-
-
Ciambrone, G.J.1
McKeown-Longo, P.J.2
-
19
-
-
0029589630
-
α-2 macroglobulin receptor/LDL receptor-related protein(LRP)-dependent internalization of the urokinase receptor
-
Conese, M., Nykjaer, A., Petersen, C. M., Cremona, O., Pardi, R., Andreasen, P. A., Gliemann, J., Christensen, E. I., and Blasi, F. (1995). α-2 macroglobulin receptor/LDL receptor-related protein(LRP)-dependent internalization of the urokinase receptor. J. Cell Biol. 131, 1609-1622.
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1609-1622
-
-
Conese, M.1
Nykjaer, A.2
Petersen, C.M.3
Cremona, O.4
Pardi, R.5
Andreasen, P.A.6
Gliemann, J.7
Christensen, E.I.8
Blasi, F.9
-
20
-
-
0034756167
-
Direct binding of occupied urokinase receptor (uPA-R) to LDL receptor-related protein is required for endocytosis of uPA-R and regulation of cell surface urokinase activity
-
Czekay, R. P., Kuemmel, T. A., Orlando, R. A., and Farquhar, M. G. (2001). Direct binding of occupied urokinase receptor (uPA-R) to LDL receptor-related protein is required for endocytosis of uPA-R and regulation of cell surface urokinase activity. Mol. Biol. Cell 12, 1467-1479.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1467-1479
-
-
Czekay, R.P.1
Kuemmel, T.A.2
Orlando, R.A.3
Farquhar, M.G.4
-
21
-
-
0037416209
-
Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins
-
Czekay, R. P., Aertgeerts, K., Curriden, S. A., and Loskutoff , D. J. (2003). Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins. J. Cell Biol. 160, 781-791.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 781-791
-
-
Czekay, R.P.1
Aertgeerts, K.2
Curriden, S.A.3
Loskutoff, D.J.4
-
22
-
-
0033566354
-
Src-dependence and pertussis-toxin sensitivity of urokinase receptor-dependent chemotaxis, and cytoskeleton reorganization in rat smooth muscle cells via the urokinase receptor
-
Degryse, B., Resnati, M., Rabbani, S. A., Villa, A., Fazioli, F., and Blasi, F. (1999). Src-dependence and pertussis-toxin sensitivity of urokinase receptor-dependent chemotaxis, and cytoskeleton reorganization in rat smooth muscle cells via the urokinase receptor. Blood 94, 649-662.
-
(1999)
Blood
, vol.94
, pp. 649-662
-
-
Degryse, B.1
Resnati, M.2
Rabbani, S.A.3
Villa, A.4
Fazioli, F.5
Blasi, F.6
-
23
-
-
0035848682
-
Urokinase/urokinase receptor and vitronectin/αvβ3 integrin induce chemotaxis and cytoskeleton reorganization through different signaling pathways
-
Degryse, B., Orlando, S., Resnati, M., Rabbani, S. A., and Blasi, F. (2001). Urokinase/urokinase receptor and vitronectin/αvβ3 integrin induce chemotaxis and cytoskeleton reorganization through different signaling pathways. Oncogene 20, 2032-2043.
-
(2001)
Oncogene
, vol.20
, pp. 2032-2043
-
-
Degryse, B.1
Orlando, S.2
Resnati, M.3
Rabbani, S.A.4
Blasi, F.5
-
24
-
-
0027219030
-
Urokinase-urokinase receptor interaction: Non-mitogenic signal transduction in human epidermal cells
-
Del Rosso, M., Anichini, E., Pedersen, N., Blasi, F., Fibbi, G., Pucci, M., and Ruggiero, M. (1993). Urokinase-urokinase receptor interaction: non-mitogenic signal transduction in human epidermal cells. Biochem. Biophys. Res. Commun. 190, 347-352.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.190
, pp. 347-352
-
-
Del Rosso, M.1
Anichini, E.2
Pedersen, N.3
Blasi, F.4
Fibbi, G.5
Pucci, M.6
Ruggiero, M.7
-
25
-
-
0029816265
-
Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?
-
Deng, G., Curriden, S. A., Wang, S., Rosenberg, S., and Loskutoff, D. (1996). Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release? J. Cell Biol. 134, 1563-1571.
-
(1996)
J. Cell Biol.
, vol.134
, pp. 1563-1571
-
-
Deng, G.1
Curriden, S.A.2
Wang, S.3
Rosenberg, S.4
Loskutoff, D.5
-
26
-
-
0034830757
-
Plasminogen activator inhibitor-1 regulates cell adhesion by binding to the somatomedin B domain of vitronectin
-
Deng, G., Curriden, S. A., Hu, G., Czekay, R. P., and Loskutoff, D. J. (2001). Plasminogen activator inhibitor-1 regulates cell adhesion by binding to the somatomedin B domain of vitronectin. J. Cell Physiol. 189, 23-33.
-
(2001)
J. Cell Physiol.
, vol.189
, pp. 23-33
-
-
Deng, G.1
Curriden, S.A.2
Hu, G.3
Czekay, R.P.4
Loskutoff, D.J.5
-
27
-
-
18244389007
-
The pro- or anti-angiogenic effect of plasminogen activator inhibitor 1 is dose dependent
-
Devy, L., Blacher, S., Grignet-Debrus, C., Bajou, K., Masson, V., Gerard, R. D., Gils, A., Carmeliet, G., Carmeliet, P., Declerck, P. J., Noel, A., Foidart, J. M. (2002). The pro- or anti-angiogenic effect of plasminogen activator inhibitor 1 is dose dependent. FASEB J. 16, 147-154.
-
(2002)
FASEB J.
, vol.16
, pp. 147-154
-
-
Devy, L.1
Blacher, S.2
Grignet-Debrus, C.3
Bajou, K.4
Masson, V.5
Gerard, R.D.6
Gils, A.7
Carmeliet, G.8
Carmeliet, P.9
Declerck, P.J.10
Noel, A.11
Foidart, J.M.12
-
28
-
-
0033588250
-
Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells
-
Dumler, I., Kopmann, A., Wagner, K., Mayboroda, O. A., Jerke, U., Dietz, R., Haller, H., and Gulba, D. C. (1999a). Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells. J. Biol. Chem. 274, 24059-24065.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 24059-24065
-
-
Dumler, I.1
Kopmann, A.2
Wagner, K.3
Mayboroda, O.A.4
Jerke, U.5
Dietz, R.6
Haller, H.7
Gulba, D.C.8
-
29
-
-
0033576631
-
Urokinase-induced mitogenesis is mediated by casein kinase 2 and nucleolin
-
Dumler, I., Stepanova, V., Jerke, U., Mayboroda, O. A., Vogel, F., Bouvet, P., Tkachuk, V., Haller, H., and Gulba, D. C. (1999b). Urokinase-induced mitogenesis is mediated by casein kinase 2 and nucleolin. Curr. Biol. 9, 1468-1476.
-
(1999)
Curr. Biol.
, vol.9
, pp. 1468-1476
-
-
Dumler, I.1
Stepanova, V.2
Jerke, U.3
Mayboroda, O.A.4
Vogel, F.5
Bouvet, P.6
Tkachuk, V.7
Haller, H.8
Gulba, D.C.9
-
30
-
-
0031463337
-
A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity
-
Fazioli, F., Resnati, M., Sidenius, N., Higashimoto, Y, Appella, E., and Blasi, F. (1997). A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity. EMBO J. 16, 7279-7286.
-
(1997)
EMBO J.
, vol.16
, pp. 7279-7286
-
-
Fazioli, F.1
Resnati, M.2
Sidenius, N.3
Higashimoto, Y.4
Appella, E.5
Blasi, F.6
-
31
-
-
0024239460
-
Interaction of urokinase with specific receptors stimulates mobilization of bovine adrenal capillary endothelial cells
-
Fibbi, G., Ziche, M., Morbidelli, L., Magnelli, L., and Del Rosso, M. (1988). Interaction of urokinase with specific receptors stimulates mobilization of bovine adrenal capillary endothelial cells. Exp. Cell Res. 179, 385-395.
-
(1988)
Exp. Cell Res.
, vol.179
, pp. 385-395
-
-
Fibbi, G.1
Ziche, M.2
Morbidelli, L.3
Magnelli, L.4
Del Rosso, M.5
-
32
-
-
0032582802
-
Urokinase induces proliferation of human ovarian cancer cells: Characterization of structural elements required for growth factor function
-
Fischer, K., Lutz, V., Wilhelm, O., Schmitt, M., Graeff, H., Heiss, P., Nishiguchi, T., Harbeck, N., Kessler, H., Luther, T., Magdolen, V., and Reuning, U. (1998). Urokinase induces proliferation of human ovarian cancer cells: characterization of structural elements required for growth factor function. FEBS Lett. 438, 101-105.
-
(1998)
FEBS Lett.
, vol.438
, pp. 101-105
-
-
Fischer, K.1
Lutz, V.2
Wilhelm, O.3
Schmitt, M.4
Graeff, H.5
Heiss, P.6
Nishiguchi, T.7
Harbeck, N.8
Kessler, H.9
Luther, T.10
Magdolen, V.11
Reuning, U.12
-
33
-
-
0343049157
-
Mapping part of the functional epitope for ligand binding on the receptor for urokinase-type plasminogen activator by site-directed mutagenesis
-
Gårdsvoll, H., Danø, K., and Ploug, M. (1999). Mapping part of the functional epitope for ligand binding on the receptor for urokinase-type plasminogen activator by site-directed mutagenesis. J. Biol. Chem. 274, 37995-38003.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37995-38003
-
-
Gårdsvoll, H.1
Danø, K.2
Ploug, M.3
-
34
-
-
0032079548
-
Kinetic analysis of integrin-dependent cell adhesion on vitronectin - The inhibitory potential of plasminogen activator inhibitor-1 and RGD peptides
-
Germer, M., Kanse, S. M., Kirkegaard, T., Kjoller, L., Felding-Habermann, B., Goodman, S., and Preissner, K. T. (1998). Kinetic analysis of integrin-dependent cell adhesion on vitronectin - the inhibitory potential of plasminogen activator inhibitor-1 and RGD peptides. Eur. J. Biochem. 253, 669-674.
-
(1998)
Eur. J. Biochem.
, vol.253
, pp. 669-674
-
-
Germer, M.1
Kanse, S.M.2
Kirkegaard, T.3
Kjoller, L.4
Felding-Habermann, B.5
Goodman, S.6
Preissner, K.T.7
-
35
-
-
0034604635
-
Urinary-type plasminogen activator (uPA) expression and uPA receptor localization are regulated by α3β1 integrin in oral keratinocytes
-
Ghosh, S., Brown, R., Jones, J. C. R., Ellerbroek, S. M., and Stack, S. (2000). Urinary-type plasminogen activator (uPA) expression and uPA receptor localization are regulated by α3β1 integrin in oral keratinocytes. J. Biol. Chem. 275, 23869-23876.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23869-23876
-
-
Ghosh, S.1
Brown, R.2
Jones, J.C.R.3
Ellerbroek, S.M.4
Stack, S.5
-
36
-
-
0033551899
-
Integrin signaling
-
Giancotti, F. G. and Ruoslahti, E. (1999). Integrin signaling. Science 285, 1028-1032.
-
(1999)
Science
, vol.285
, pp. 1028-1032
-
-
Giancotti, F.G.1
Ruoslahti, E.2
-
37
-
-
0023229547
-
Human urokinase-type plasminogen activator stimulates chemotaxis of human neutrophils
-
Gudewicz, P. W. and Gilboa, N. (1987). Human urokinase-type plasminogen activator stimulates chemotaxis of human neutrophils. Biochem. Biophys. Res. Commun. 147, 1176-1181.
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.147
, pp. 1176-1181
-
-
Gudewicz, P.W.1
Gilboa, N.2
-
38
-
-
0034667385
-
Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1
-
Gutierrez, L. S., Schulman, A., Brito-Robinson, T., Noria, F., Ploplis, V. A., and Castellino, F. J. (2000). Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1. Cancer Res. 60, 5839-5847.
-
(2000)
Cancer Res.
, vol.60
, pp. 5839-5847
-
-
Gutierrez, L.S.1
Schulman, A.2
Brito-Robinson, T.3
Noria, F.4
Ploplis, V.A.5
Castellino, F.J.6
-
39
-
-
0035854735
-
Integrin αvβ3/vitronectin interaction affects expression of the urokinase system in human ovarian cancer cells
-
Hapke, S., Kessler, H., Arroyo de Prada, N., Benge, A., Schmitt, M., Lengyel, E., and Reuning, U. (2001a). Integrin αvβ3/vitronectin interaction affects expression of the urokinase system in human ovarian cancer cells. J. Biol. Chem. 276, 26340-26348.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26340-26348
-
-
Hapke, S.1
Kessler, H.2
Arroyo de Prada, N.3
Benge, A.4
Schmitt, M.5
Lengyel, E.6
Reuning, U.7
-
40
-
-
0035015311
-
β(3)A-integrin downregulates the urokinase-type plasminogen activator receptor (uPA-R) through a PEA3/ets transcriptional silencing element in the uPA-R promoter
-
Hapke, S., Gawaz, M., Dehne, K., Köhler, J., Marshall, J. F., Graeff, H., Schmitt, M., Reuning, U., and Lengyel, E. (2001b). β(3)A-integrin downregulates the urokinase-type plasminogen activator receptor (uPA-R) through a PEA3/ets transcriptional silencing element in the uPA-R promoter. Mol. Cell. Biol. 21, 2118-2132.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2118-2132
-
-
Hapke, S.1
Gawaz, M.2
Dehne, K.3
Köhler, J.4
Marshall, J.F.5
Graeff, H.6
Schmitt, M.7
Reuning, U.8
Lengyel, E.9
-
41
-
-
0036734093
-
A reevaluation of integrins as regulators of angiogenesis
-
Hynes, R. O. (2002). A reevaluation of integrins as regulators of angiogenesis. Nature Med. 8, 918-921.
-
(2002)
Nature Med.
, vol.8
, pp. 918-921
-
-
Hynes, R.O.1
-
42
-
-
0033213996
-
The plasminogen activator system: Biology and regulation
-
Irigoyen, J. P., Munoz-Canoves, P., Montero, L., Koziczak, M., and Nagamine, Y. (1999). The plasminogen activator system: biology and regulation. Cell. Mol. Life Sci. 56, 104-132.
-
(1999)
Cell. Mol. Life Sci.
, vol.56
, pp. 104-132
-
-
Irigoyen, J.P.1
Munoz-Canoves, P.2
Montero, L.3
Koziczak, M.4
Nagamine, Y.5
-
43
-
-
0035878864
-
Plasminogen activator inhibitor-1 promotes angiogenesis by stimulating endothelial cell migration toward fibronectin
-
Isogai, C., Laug, W. E., Shimada, H., Declerck, P. J., Stins, M. F., Durden, D. L., Erdreich-Epstein, A., and DeClerck, Y. A. (2001). Plasminogen activator inhibitor-1 promotes angiogenesis by stimulating endothelial cell migration toward fibronectin. Cancer Res. 61, 5587-5594.
-
(2001)
Cancer Res.
, vol.61
, pp. 5587-5594
-
-
Isogai, C.1
Laug, W.E.2
Shimada, H.3
Declerck, P.J.4
Stins, M.F.5
Durden, D.L.6
Erdreich-Epstein, A.7
DeClerck, Y.A.8
-
44
-
-
0036430572
-
Collagen modulates gene activation of plasminogen activator system molecules
-
Jones, J. M., Cohen, R. L., and Chambers, D. A. (2002). Collagen modulates gene activation of plasminogen activator system molecules. Exp. Cell Res. 280, 244-254.
-
(2002)
Exp. Cell Res.
, vol.280
, pp. 244-254
-
-
Jones, J.M.1
Cohen, R.L.2
Chambers, D.A.3
-
45
-
-
0029873910
-
The urokinase receptor is a major vitronectin-binding protein on endothelial cells
-
Kanse, S., Kost, C., Wilhelm, O., Andreasen, P. A., and Preissner, K. T. (1996). The urokinase receptor is a major vitronectin-binding protein on endothelial cells. Exp. Cell Res. 224, 344-353.
-
(1996)
Exp. Cell Res.
, vol.224
, pp. 344-353
-
-
Kanse, S.1
Kost, C.2
Wilhelm, O.3
Andreasen, P.A.4
Preissner, K.T.5
-
46
-
-
0031471689
-
Induction of vascular SMC proliferation by urokinase indicates a novel mechanism of action in vasoproliferative disorders
-
Kanse, S. M., Benzakour, O., Kanthou, C., Kost, C., Lijnen, H. R., and Preissner, K. T. (1997). Induction of vascular SMC proliferation by urokinase indicates a novel mechanism of action in vasoproliferative disorders. Arterioscler. Thromb. Vasc. Biol. 17, 2848-2854.
-
(1997)
Arterioscler. Thromb. Vasc. Biol.
, vol.17
, pp. 2848-2854
-
-
Kanse, S.M.1
Benzakour, O.2
Kanthou, C.3
Kost, C.4
Lijnen, H.R.5
Preissner, K.T.6
-
47
-
-
0035255023
-
Regulation of urokinase plasminogen activator/plasmin-mediated invasion of melanoma cells by the integrin vitronectin receptor αvβ3
-
Khatib, A. M., Nip, J., Fallavollita, L., Lehmann, M., Jensen, G., and Brodt, P. (2001). Regulation of urokinase plasminogen activator/plasmin-mediated invasion of melanoma cells by the integrin vitronectin receptor αvβ3. Int. J. Cancer 91, 300-308.
-
(2001)
Int. J. Cancer
, vol.91
, pp. 300-308
-
-
Khatib, A.M.1
Nip, J.2
Fallavollita, L.3
Lehmann, M.4
Jensen, G.5
Brodt, P.6
-
48
-
-
0023603282
-
Proliferation of a human epidermal tumor cell line stimulated by urokinase
-
Kirchheimer, J. C., Wojta, J., Christ, G., and Binder, B. R. (1987). Proliferation of a human epidermal tumor cell line stimulated by urokinase. FASEB J. 1, 125-128.
-
(1987)
FASEB J.
, vol.1
, pp. 125-128
-
-
Kirchheimer, J.C.1
Wojta, J.2
Christ, G.3
Binder, B.R.4
-
49
-
-
0024513665
-
Growth stimulation of human epidermal cells by urokinase is restricted to the intact active enzyme
-
Kirchheimer, J. C., Christ, G., and Binder, B. R. (1989a). Growth stimulation of human epidermal cells by urokinase is restricted to the intact active enzyme. Eur. J. Biochem. 181, 103-107.
-
(1989)
Eur. J. Biochem.
, vol.181
, pp. 103-107
-
-
Kirchheimer, J.C.1
Christ, G.2
Binder, B.R.3
-
50
-
-
2042503759
-
Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line
-
Kirchheimer, J. C., Wojta, J., Christ, G., and Binder, B. R. (1989b). Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line. Proc. Natl. Acad. Sci. USA 86, 5424-5428.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5424-5428
-
-
Kirchheimer, J.C.1
Wojta, J.2
Christ, G.3
Binder, B.R.4
-
51
-
-
0035911966
-
Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin
-
Kjøller, L. and Hall, A. (2001). Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin. J. Cell Biol. 152, 1145-1157.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 1145-1157
-
-
Kjøller, L.1
Hall, A.2
-
52
-
-
0000124642
-
Plasminogen activator inhibitor-1 represses integrin- and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation
-
Kjøller, L., Kanse, S. M., Kirkegaard, T., Rodenburg, K. W., Rønne, E., Goodman, S. L., Preissner, K. T., Ossowski, L., and Andreasen, P. A. (1997). Plasminogen activator inhibitor-1 represses integrin- and vitronectin-mediated cell migration independently of its function as an inhibitor of plasminogen activation. Exp. Cell Res. 232, 420-429.
-
(1997)
Exp. Cell Res.
, vol.232
, pp. 420-429
-
-
Kjøller, L.1
Kanse, S.M.2
Kirkegaard, T.3
Rodenburg, K.W.4
Rønne, E.5
Goodman, S.L.6
Preissner, K.T.7
Ossowski, L.8
Andreasen, P.A.9
-
53
-
-
0023572111
-
Plasminogen activator inhibitor is associated with the extracellular matrix of cultured bovine smooth muscle cells
-
Knudsen, B. S., Hapel, P. C., and Nachman, R. L. (1987). Plasminogen activator inhibitor is associated with the extracellular matrix of cultured bovine smooth muscle cells. J. Clin. Invest. 80, 1082-1089.
-
(1987)
J. Clin. Invest.
, vol.80
, pp. 1082-1089
-
-
Knudsen, B.S.1
Hapel, P.C.2
Nachman, R.L.3
-
54
-
-
0030716909
-
Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598
-
Koshelnick, Y., Ehart, M., Hufnagl, P., Heinrich, R C., and Binder, B. R. (1997). Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598. J. Biol. Chem. 272, 28563-28567.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28563-28567
-
-
Koshelnick, Y.1
Ehart, M.2
Hufnagl, P.3
Heinrich, R.C.4
Binder, B.R.5
-
55
-
-
0034671928
-
Urokinase stimulates human vascular smooth muscle cell migration via a phosphatidylinositol 3-kinase-Tyk2 interaction
-
Kusch, A., Tkachuk, S., Haller, H., Dietz, R., Gulba, D. C., Lipp, M., and Dumler, I. (2000). Urokinase stimulates human vascular smooth muscle cell migration via a phosphatidylinositol 3-kinase-Tyk2 interaction. J. Biol. Chem. 275, 39466-39473.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39466-39473
-
-
Kusch, A.1
Tkachuk, S.2
Haller, H.3
Dietz, R.4
Gulba, D.C.5
Lipp, M.6
Dumler, I.7
-
56
-
-
0030898213
-
Characterization of the binding of different conformational forms of plasminogen activator inhibitor-1 to vitronectin. Implications for the regulation of pericellular proteolysis
-
Lawrence, D. A., Palaniappan, S., Stefansson, S., Olson, S. T., Francis-Chmura, A. M., Shore, J. D., and Ginsburg, D. (1997). Characterization of the binding of different conformational forms of plasminogen activator inhibitor-1 to vitronectin. Implications for the regulation of pericellular proteolysis. J. Biol. Chem. 272, 7676-7680.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7676-7680
-
-
Lawrence, D.A.1
Palaniappan, S.2
Stefansson, S.3
Olson, S.T.4
Francis-Chmura, A.M.5
Shore, J.D.6
Ginsburg, D.7
-
57
-
-
0036083189
-
Cell adhesion regulates the plasminogen activator inhibitor-1 gene expression in anchorage-dependent cells
-
Lee, C. C., Shyu, K. G., Lin, S., Wang, B. W., Liu, Y C., and Chang, H. (2002). Cell adhesion regulates the plasminogen activator inhibitor-1 gene expression in anchorage-dependent cells. Biochem. Biophys. Res. Commun. 291, 185-190.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.291
, pp. 185-190
-
-
Lee, C.C.1
Shyu, K.G.2
Lin, S.3
Wang, B.W.4
Liu, Y.C.5
Chang, H.6
-
58
-
-
0033003218
-
Regulation of cell adhesion by PAI-1
-
Loskutoff, D. J., Curriden, S. A., Hu, G., and Deng, G. (1999). Regulation of cell adhesion by PAI-1. APMIS 107, 54-61.
-
(1999)
APMIS
, vol.107
, pp. 54-61
-
-
Loskutoff, D.J.1
Curriden, S.A.2
Hu, G.3
Deng, G.4
-
59
-
-
9344234400
-
Systematic mutational analysis of the receptor-binding region of the human urokinase-type plasminogen activator
-
Magdolen, V., Rettenberger, P., Koppitz, M., Goretzki, L., Kessler, H., Weidle, U. H., König, B., Graeff, H., Schmitt, M., and Wilhelm, O. (1996). Systematic mutational analysis of the receptor-binding region of the human urokinase-type plasminogen activator. Eur. J. Biochem. 237, 743-751.
-
(1996)
Eur. J. Biochem.
, vol.237
, pp. 743-751
-
-
Magdolen, V.1
Rettenberger, P.2
Koppitz, M.3
Goretzki, L.4
Kessler, H.5
Weidle, U.H.6
König, B.7
Graeff, H.8
Schmitt, M.9
Wilhelm, O.10
-
60
-
-
0032555894
-
Urokinase receptor (CD87) regulates leukocyte recruitment via β 2 integrins in vivo
-
May, A. E., Kanse, S. M., Lund, L. R., Gisler, R. H., Imhof, B. A., and Preissner, K. T. (1998). Urokinase receptor (CD87) regulates leukocyte recruitment via β 2 integrins in vivo. J. Exp. Med. 188, 1029-1037.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1029-1037
-
-
May, A.E.1
Kanse, S.M.2
Lund, L.R.3
Gisler, R.H.4
Imhof, B.A.5
Preissner, K.T.6
-
61
-
-
0035823504
-
Plasminogen activator inhibitor-1 regulates tumor growth and angiogenesis
-
McMahon, G. A., Petitclerc, E., Stefansson, S., Smith, E., Wong, M. K., Westrick, R. J., Ginsburg, D., Brooks, P. C., and Lawrence, D. A. (2001). Plasminogen activator inhibitor-1 regulates tumor growth and angiogenesis. J. Biol. Chem. 276, 33964-33968.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33964-33968
-
-
McMahon, G.A.1
Petitclerc, E.2
Stefansson, S.3
Smith, E.4
Wong, M.K.5
Westrick, R.J.6
Ginsburg, D.7
Brooks, P.C.8
Lawrence, D.A.9
-
62
-
-
0028962771
-
Coordinated expression of the vitronectin receptor and the urokinase-type plasminogen activator receptor in metastatic melanoma cells
-
Nip, J., Rabbani, S. A., Shibata, H. R., and Brodt, P. (1995). Coordinated expression of the vitronectin receptor and the urokinase-type plasminogen activator receptor in metastatic melanoma cells. J. Clin. Invest. 95, 2096-2103.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 2096-2103
-
-
Nip, J.1
Rabbani, S.A.2
Shibata, H.R.3
Brodt, P.4
-
63
-
-
0001353920
-
Purified α2-macroglobulin receptor/LDL receptor-related protein binds urokinase-plasminogen activcator inhibitor type-1 complex. Evidence that the α2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes
-
Nykjær, A., Petersen, C. M., Moller, B., Jensen, P. H., Moestrup, S. K., Holtet, T. L., Etzerodt, M., Thogersen, H. C., Munch, M., Andreasen, P. A. (1992). Purified α2-macroglobulin receptor/LDL receptor-related protein binds urokinase-plasminogen activcator inhibitor type-1 complex. Evidence that the α2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes. J. Biol. Chem. 267, 14543-14546.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 14543-14546
-
-
Nykjær, A.1
Petersen, C.M.2
Moller, B.3
Jensen, P.H.4
Moestrup, S.K.5
Holtet, T.L.6
Etzerodt, M.7
Thogersen, H.C.8
Munch, M.9
Andreasen, P.A.10
-
64
-
-
0027999481
-
Regions involved in binding of urokinase-type-1 inhibitor complex and pro-urokinase to the endocytic α2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that the urokinase receptor protects pro-urokinase against binding to the endocytic receptor
-
Nykjaer, A., Kjøller, L., Cohen, R. L., Lawrence, D. A., Garni-Wagner, B. A., Todd, R. F. 3rd, van Zonneveld, A. J., Gliemann, J., and Andreasen, P. A. (1994). Regions involved in binding of urokinase-type-1 inhibitor complex and pro-urokinase to the endocytic α2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that the urokinase receptor protects pro-urokinase against binding to the endocytic receptor. J. Biol. Chem. 14, 25668-25676.
-
(1994)
J. Biol. Chem.
, vol.14
, pp. 25668-25676
-
-
Nykjaer, A.1
Kjøller, L.2
Cohen, R.L.3
Lawrence, D.A.4
Garni-Wagner, B.A.5
Todd R.F. III6
van Zonneveld, A.J.7
Gliemann, J.8
Andreasen, P.A.9
-
65
-
-
0030926412
-
Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes
-
Nykjaer, A., Conese, M., Christensen, E. I., Olson, D., Cremona, O., Gliemann, J., and Blasi, F. (1997). Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes. EMBO J. 16, 2610-2620.
-
(1997)
EMBO J.
, vol.16
, pp. 2610-2620
-
-
Nykjaer, A.1
Conese, M.2
Christensen, E.I.3
Olson, D.4
Cremona, O.5
Gliemann, J.6
Blasi, F.7
-
66
-
-
0037088573
-
Kinetic analysis of the interaction between vitronectin and the urokinase receptor
-
Okumura, Y., Kamikubo, Y., Curriden, S. A., Wang, J., Kiwada, T., Futaki, S., Kitagawa, K., and Loskutoff, D. J. (2002). Kinetic analysis of the interaction between vitronectin and the urokinase receptor. J. Biol. Chem. 277, 9395-9404.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9395-9404
-
-
Okumura, Y.1
Kamikubo, Y.2
Curriden, S.A.3
Wang, J.4
Kiwada, T.5
Futaki, S.6
Kitagawa, K.7
Loskutoff, D.J.8
-
67
-
-
0033824172
-
Urokinase receptor and integrin partnership: Coordination of signaling for cell adhesion, migration and growth
-
Ossowski, L. and Aguirre-Ghiso, J. A. (2000). Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth. Curr. Opin. Cell Biol. 12, 613-620.
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 613-620
-
-
Ossowski, L.1
Aguirre-Ghiso, J.A.2
-
68
-
-
0032564309
-
Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPA-R domains I and III participate in the assembly of a composite ligand-binding site
-
Ploug, M. (1998). Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPA-R domains I and III participate in the assembly of a composite ligand-binding site. Biochemistry 37, 16494-16505.
-
(1998)
Biochemistry
, vol.37
, pp. 16494-16505
-
-
Ploug, M.1
-
69
-
-
0037441743
-
Convergence of the adhesive and fibrinolytic systems: Recognition of urokinase by integrin αM β2 as well as by the urokinase receptor regulates cell adhesion and migration
-
Pluskota, E., Soloviev, D. A., and Plow, E. F. (2003). Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin αM β2 as well as by the urokinase receptor regulates cell adhesion and migration. Blood 101, 1582-1590.
-
(2003)
Blood
, vol.101
, pp. 1582-1590
-
-
Pluskota, E.1
Soloviev, D.A.2
Plow, E.F.3
-
70
-
-
0028073962
-
Fibronectin attachment activates the NF-κB p50/p65 heterodimer in fibroblasts and smooth muscle cells
-
Qwarnström, E. E., Ostberg, C. O., Turk, G. L., Richardson, C. A., and Bomstyk, K. (1994). Fibronectin attachment activates the NF-κB p50/p65 heterodimer in fibroblasts and smooth muscle cells. J. Biol. Chem. 269, 30765-30768.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30765-30768
-
-
Qwarnström, E.E.1
Ostberg, C.O.2
Turk, G.L.3
Richardson, C.A.4
Bomstyk, K.5
-
71
-
-
0025543131
-
An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells
-
Rabbani, S. A., Desjardins, J., Bell, A. W., Banville, D., Mazar, A., Henkin, J., and Goltzman, D. (1990). An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells. Biochem. Biophys. Res. Commun. 173, 1058-1064.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.173
, pp. 1058-1064
-
-
Rabbani, S.A.1
Desjardins, J.2
Bell, A.W.3
Banville, D.4
Mazar, A.5
Henkin, J.6
Goltzman, D.7
-
72
-
-
0029923744
-
Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect
-
Resnati, M., Guttinger, M., Valcamonica, S., Sidenius, N., Blasi, F., and Fazioli, F. (1996). Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect. EMBO J. 15, 1572-1582.
-
(1996)
EMBO J.
, vol.15
, pp. 1572-1582
-
-
Resnati, M.1
Guttinger, M.2
Valcamonica, S.3
Sidenius, N.4
Blasi, F.5
Fazioli, F.6
-
73
-
-
0037022391
-
The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R
-
Resnati, M., Pallavicini, I., Wang, J. M., Oppenheim, J., Serhan, C. N., Romano, M., and Blasi, F. (2002). The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R. Proc. Natl. Acad. Sci. USA 99, 1359-1364.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1359-1364
-
-
Resnati, M.1
Pallavicini, I.2
Wang, J.M.3
Oppenheim, J.4
Serhan, C.N.5
Romano, M.6
Blasi, F.7
-
74
-
-
0031733174
-
Multifunctional potential of the plasminogen activation system in tumor invasion and metastasis
-
Reuning, U., Magdolen, V., Wilhelm, O., Fischer, K., Lutz, V., and Schmitt, M. (1998). Multifunctional potential of the plasminogen activation system in tumor invasion and metastasis. Int. J. Oncol. 3, 893-906.
-
(1998)
Int. J. Oncol.
, vol.3
, pp. 893-906
-
-
Reuning, U.1
Magdolen, V.2
Wilhelm, O.3
Fischer, K.4
Lutz, V.5
Schmitt, M.6
-
75
-
-
0033555244
-
Rel transcription factors contribute to elevated urokinase expression in human ovarian carcinoma cells
-
Reuning, U., Guerrini, L., Nishiguchi, T., Page, S., Seibold, H., Magdolen, V., and Schmitt, M. (1999). Rel transcription factors contribute to elevated urokinase expression in human ovarian carcinoma cells. Eur. J. Biochem. 259, 143-148.
-
(1999)
Eur. J. Biochem.
, vol.259
, pp. 143-148
-
-
Reuning, U.1
Guerrini, L.2
Nishiguchi, T.3
Page, S.4
Seibold, H.5
Magdolen, V.6
Schmitt, M.7
-
76
-
-
0026892236
-
Tumor-associated urokinase-type plasminogen activator: Biological and clinical significance
-
Schmitt, M., Jänicke, F., Moniwa, N., Chucholowski, N., Pache, L., and Graeff, H. (1992). Tumor-associated urokinase-type plasminogen activator: biological and clinical significance. Biol. Chem. Hoppe-Seyler 373, 611-622.
-
(1992)
Biol. Chem. Hoppe-Seyler
, vol.373
, pp. 611-622
-
-
Schmitt, M.1
Jänicke, F.2
Moniwa, N.3
Chucholowski, N.4
Pache, L.5
Graeff, H.6
-
77
-
-
0030857717
-
Clinical impact of the plasminogen activation system in tumor invasion and metastasis: Prognostic relevance and target for therapy
-
Schmitt, M., Harbeck, N., Thomssen, C., Wilhelm, O., Magdolen, V., Reuning, U., Ulm, K., Höfler, H., Jänicke, F., and Graeff, H. (1997). Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy. Thromb. Haemost. 78, 285-296.
-
(1997)
Thromb. Haemost.
, vol.78
, pp. 285-296
-
-
Schmitt, M.1
Harbeck, N.2
Thomssen, C.3
Wilhelm, O.4
Magdolen, V.5
Reuning, U.6
Ulm, K.7
Höfler, H.8
Jänicke, F.9
Graeff, H.10
-
78
-
-
0036661077
-
Interaction of plasminogen activator inhibitor type-1 (PAI-1) with vitronectin (Vn): Mapping the binding sites on PAI-1 and Vn
-
Schroeck, F., Arroyo de Prada, N., Sperl, S., Schmitt, M., and Magdolen, V. (2002) Interaction of plasminogen activator inhibitor type-1 (PAI-1) with vitronectin (Vn): mapping the binding sites on PAI-1 and Vn. Biol. Chem. 383, 1143-1149.
-
(2002)
Biol. Chem.
, vol.383
, pp. 1143-1149
-
-
Schroeck, F.1
Arroyo de Prada, N.2
Sperl, S.3
Schmitt, M.4
Magdolen, V.5
-
79
-
-
0035052269
-
Expression of the urokinase-type plasminogen activator receptor in human articular association with caveolin and β1-integrin
-
Schwab, W., Gavlik, J. M., Beichler, T., Funk, R. H., Albrecht, S., Magdolen, V., Luther, T., Kasper, M., and Shakibaei, M. (2001). Expression of the urokinase-type plasminogen activator receptor in human articular association with caveolin and β1-integrin. Histochem. Cell. Biol. 115, 317-323.
-
(2001)
Histochem. Cell. Biol.
, vol.115
, pp. 317-323
-
-
Schwab, W.1
Gavlik, J.M.2
Beichler, T.3
Funk, R.H.4
Albrecht, S.5
Magdolen, V.6
Luther, T.7
Kasper, M.8
Shakibaei, M.9
-
80
-
-
0035575458
-
Integrin signaling revisited
-
Schwartz, M. A. (2001). Integrin signaling revisited. Trends Cell Biol. 12, 466-470.
-
(2001)
Trends Cell Biol.
, vol.12
, pp. 466-470
-
-
Schwartz, M.A.1
-
81
-
-
0025774971
-
Evidence that type 1 plasminogen activator inhibitor binds to the somatomedin B domain of vitronectin
-
Seiffert, D. and Loskutoff, D. J. (1991). Evidence that type 1 plasminogen activator inhibitor binds to the somatomedin B domain of vitronectin. J. Biol. Chem. 266, 2824-2830.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 2824-2830
-
-
Seiffert, D.1
Loskutoff, D.J.2
-
82
-
-
0037008781
-
Urokinase regulates vitronectin binding by controlling urokinase receptor oligomerization
-
Sidenius, N., Andolfo, A., Fesce, R., and Blasi, F. (2002). Urokinase regulates vitronectin binding by controlling urokinase receptor oligomerization. J. Biol. Chem. 277, 27982-27990.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27982-27990
-
-
Sidenius, N.1
Andolfo, A.2
Fesce, R.3
Blasi, F.4
-
83
-
-
0037146757
-
Engaged urokinase receptors enhance tumor breast cell migration and invasion by upregulating αvβ5 vitronectin receptor cell surface expression
-
Silvestri, I., Longanesi Cattani, I., Franco, P., Pirozzi, G., Botti, G., Stoppelli, M. P., and Carriero, M. V. (2002). Engaged urokinase receptors enhance tumor breast cell migration and invasion by upregulating αvβ5 vitronectin receptor cell surface expression. Int. J. Cancer 102, 562-571.
-
(2002)
Int. J. Cancer
, vol.102
, pp. 562-571
-
-
Silvestri, I.1
Longanesi Cattani, I.2
Franco, P.3
Pirozzi, G.4
Botti, G.5
Stoppelli, M.P.6
Carriero, M.V.7
-
84
-
-
0029958368
-
The leukocyte integrin Mac-1 (CD11b/CD18) and the urokinase receptor (uPA-R, CD87) mediate complementary functions in myelomonocytic cells
-
Simon, D. I., Rao, N. K., Xu, H., Wei, Y., Majdic, O., Rönne, E., Kobzik, L., and Chapman, H. A. (1996). The leukocyte integrin Mac-1 (CD11b/CD18) and the urokinase receptor (uPA-R, CD87) mediate complementary functions in myelomonocytic cells. Blood 88, 3185-3194.
-
(1996)
Blood
, vol.88
, pp. 3185-3194
-
-
Simon, D.I.1
Rao, N.K.2
Xu, H.3
Wei, Y.4
Majdic, O.5
Rönne, E.6
Kobzik, L.7
Chapman, H.A.8
-
85
-
-
0034616388
-
Identification of a urokinase receptor-integrin interaction site: Promiscuous regulator of integrin function
-
Simon, D. I., Wei, Y., Zhang, L., Rao, N. K., Xu, H., Chen, Z., Liu, Q., Rosenberg, S., and Chapman, H. A. (2000). Identification of a urokinase receptor-integrin interaction site: promiscuous regulator of integrin function. J. Biol. Chem. 275, 10228-10234.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10228-10234
-
-
Simon, D.I.1
Wei, Y.2
Zhang, L.3
Rao, N.K.4
Xu, H.5
Chen, Z.6
Liu, Q.7
Rosenberg, S.8
Chapman, H.A.9
-
87
-
-
0028821827
-
Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model
-
Soff, G. A., Sanderowitz, J., Gately, S., Verrusio, E., Weiss, I., Brem, S., and Kwaan, H. C. (1995). Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model. J. Clin. Invest. 96, 2593-2600.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 2593-2600
-
-
Soff, G.A.1
Sanderowitz, J.2
Gately, S.3
Verrusio, E.4
Weiss, I.5
Brem, S.6
Kwaan, H.C.7
-
88
-
-
0028944244
-
The urokinase-type plasminogen activator receptor, a GPI-Iinked protein, is localized in caveolae
-
Stahl, A. and Mueller, B. M. (1995). The urokinase-type plasminogen activator receptor, a GPI-Iinked protein, is localized in caveolae. J. Cell Biol. 129, 335-344.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 335-344
-
-
Stahl, A.1
Mueller, B.M.2
-
89
-
-
0029745109
-
The serpin PAI-1 inhibits cell migration by blocking integrin αvβ3 binding to vitronectin
-
Stefansson, S. and Lawrence, D. A. (1996). The serpin PAI-1 inhibits cell migration by blocking integrin αvβ3 binding to vitronectin. Nature 383, 441-443.
-
(1996)
Nature
, vol.383
, pp. 441-443
-
-
Stefansson, S.1
Lawrence, D.A.2
-
90
-
-
0032513248
-
Plasminogen activator inhibitor-1 contains a cryptic high affinity binding site for the low density lipoprotein receptor-related protein
-
Stefansson, S., Muhammad, S., Cheng, X. F., Battey, F. D., Strickland, D. K., and Lawrence, D. A. (1998). Plasminogen activator inhibitor-1 contains a cryptic high affinity binding site for the low density lipoprotein receptor-related protein. J. Biol. Chem. 273, 6358-6366.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6358-6366
-
-
Stefansson, S.1
Muhammad, S.2
Cheng, X.F.3
Battey, F.D.4
Strickland, D.K.5
Lawrence, D.A.6
-
91
-
-
0035896622
-
Inhibition of angiogenesis in vivo by plasminogen activator inhibitor-1
-
Stefansson, S., Petitclerc, E., Wong, M. K., McMahon, G. A., Brooks, P. C., and Lawrence, D. A. (2001). Inhibition of angiogenesis in vivo by plasminogen activator inhibitor-1. J. Biol. Chem. 276, 8135-8141.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8135-8141
-
-
Stefansson, S.1
Petitclerc, E.2
Wong, M.K.3
McMahon, G.A.4
Brooks, P.C.5
Lawrence, D.A.6
-
92
-
-
0037155875
-
Urokinase-dependent human vascular smooth muscle cells adhesion requires selective vitronectin phorphorylation by ecto-protein kinase CK2
-
Stepanova, V., Jerke, U., Sagach, V., Lindschau, C., Dietz, R., Haller, H., and Dumler, I. (2002). Urokinase-dependent human vascular smooth muscle cells adhesion requires selective vitronectin phorphorylation by ecto-protein kinase CK2. J. Biol. Chem. 277, 10265-10272.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10265-10272
-
-
Stepanova, V.1
Jerke, U.2
Sagach, V.3
Lindschau, C.4
Dietz, R.5
Haller, H.6
Dumler, I.7
-
93
-
-
0035830838
-
Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction
-
Tarui, T., Mazar, A. P., Cines, D. B., and Takada, Y. (2001). Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction. J. Biol. Chem. 276, 3983-3990.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3983-3990
-
-
Tarui, T.1
Mazar, A.P.2
Cines, D.B.3
Takada, Y.4
-
94
-
-
0034687545
-
Soluble urokinase receptor promotes cell adhesion and requires tyrosine-92 for activation of p56/59(hck)
-
Trigwell, S., Wood, L., and Jones, P. (2000). Soluble urokinase receptor promotes cell adhesion and requires tyrosine-92 for activation of p56/59(hck). Biochem. Biophys. Res. Commun. 278, 440-446.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, pp. 440-446
-
-
Trigwell, S.1
Wood, L.2
Jones, P.3
-
95
-
-
0033609663
-
Involvement of fibronectin in the regulation of urokinase production and binding in murine mammary tumor cells
-
Urtreger, A. J., Aguirre Ghiso, J. A., Werbajh, S. E., Puricelli, L. I., Muro, A. F., and Ball De Kier Joffe, E. (1999). Involvement of fibronectin in the regulation of urokinase production and binding in murine mammary tumor cells. Int. J. Cancer 82, 748-753.
-
(1999)
Int. J. Cancer
, vol.82
, pp. 748-753
-
-
Urtreger, A.J.1
Aguirre Ghiso, J.A.2
Werbajh, S.E.3
Puricelli, L.I.4
Muro, A.F.5
Ball De Kier Joffe, E.6
-
96
-
-
0034843783
-
Urokinase-receptor/integrin complexes are functionally involved in adhesion and progression of human breast cancer in vivo
-
Van der Pluijm, G., Sijmons, B., Vloedgraven, H., van der Bent, C., Drijfhout, J. W., Verheijen, J., Quax, P, Karperien, M., Papapoulos, S., and Lowik, C. (2001). Urokinase-receptor/integrin complexes are functionally involved in adhesion and progression of human breast cancer in vivo. Am. J. Pathol. 159, 971-982.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 971-982
-
-
Van der Pluijm, G.1
Sijmons, B.2
Vloedgraven, H.3
van der Bent C. Drijfhout, J.W.4
Verheijen, J.5
Quax, P.6
Karperien, M.7
Papapoulos, S.8
Lowik, C.9
-
97
-
-
0021984227
-
A cellular binding site for the Mr 55000 form of the human plasminogen activator urokinase
-
Vasalli, J. D., Baccino, D., and Belin, D. (1985). A cellular binding site for the Mr 55000 form of the human plasminogen activator urokinase. J. Cell Biol. 100, 86-92.
-
(1985)
J. Cell Biol.
, vol.100
, pp. 86-92
-
-
Vasalli, J.D.1
Baccino, D.2
Belin, D.3
-
98
-
-
0030757506
-
Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin
-
Waltz, D. A., Natkin, L. R., Fujita, R. M., Wei, Y., and Chapman, H. A. (1997). Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin. J. Clin. Invest. 100, 58-67.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 58-67
-
-
Waltz, D.A.1
Natkin, L.R.2
Fujita, R.M.3
Wei, Y.4
Chapman, H.A.5
-
99
-
-
0034037536
-
Nonproteolytic role for the urokinase receptor in cellular migration in vivo
-
Waltz, D. A., Fujita, R. M., Yang, X., Natkin, L., Zhuo, S., Gerard, C. J., Rosenberg, S., and Chapman, H. A. (2000). Nonproteolytic role for the urokinase receptor in cellular migration in vivo. Am. J. Respir. Cell Mol. Biol. 22, 316-322.
-
(2000)
Am. J. Respir. Cell Mol. Biol.
, vol.22
, pp. 316-322
-
-
Waltz, D.A.1
Fujita, R.M.2
Yang, X.3
Natkin, L.4
Zhuo, S.5
Gerard, C.J.6
Rosenberg, S.7
Chapman, H.A.8
-
100
-
-
0028569183
-
Identification of the urokinase receptor as an adhesion receptor for vitronectin
-
Wei, Y., Waltz, D. A., Rao, N., Drummond, R. J., Rosenberg, S., and Chapman, H. A. (1994). Identification of the urokinase receptor as an adhesion receptor for vitronectin. J. Biol. Chem. 269, 32380-32388.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32380-32388
-
-
Wei, Y.1
Waltz, D.A.2
Rao, N.3
Drummond, R.J.4
Rosenberg, S.5
Chapman, H.A.6
-
101
-
-
0029764639
-
Regulation of integrin function by the urokinase receptor
-
Wei, Y., Lukashev, M., Simon, D. I., Bodary, S. C., Rosenberg, S., Doyle, M. V., and Chapman, H. A. (1996). Regulation of integrin function by the urokinase receptor. Science 273, 1551-1555.
-
(1996)
Science
, vol.273
, pp. 1551-1555
-
-
Wei, Y.1
Lukashev, M.2
Simon, D.I.3
Bodary, S.C.4
Rosenberg, S.5
Doyle, M.V.6
Chapman, H.A.7
-
102
-
-
0344507516
-
A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling
-
Wei, Y., Yang, X., Liu, Q., Wilkins, J. A., and Chapman, H. A. (1999). A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling. J. Cell Biol. 144, 1285-1294.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 1285-1294
-
-
Wei, Y.1
Yang, X.2
Liu, Q.3
Wilkins, J.A.4
Chapman, H.A.5
-
103
-
-
0035158527
-
Urokinase receptors promote β1 integrin function through interactions with integrin α3β1
-
Wei, Y., Eble, J. A., Wang, Z., Kreidberg, J. A., and Chapman, H. A. (2001). Urokinase receptors promote β1 integrin function through interactions with integrin α3β1. Mol. Biol. Cell 12, 2975-2986.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2975-2986
-
-
Wei, Y.1
Eble, J.A.2
Wang, Z.3
Kreidberg, J.A.4
Chapman, H.A.5
-
104
-
-
0033794679
-
Localization of urokinase type plasminogen activator to focal adhesions requires ligation of vitronectin integrin receptors
-
Wilcox-Adelman, S. A., Wilkins-Port C. E., and McKeown-Longo, P. J. (2000). Localization of urokinase type plasminogen activator to focal adhesions requires ligation of vitronectin integrin receptors. Cell Adhes. Commun. 7, 477-490.
-
(2000)
Cell Adhes. Commun.
, vol.7
, pp. 477-490
-
-
Wilcox-Adelman, S.A.1
Wilkins-Port, C.E.2
McKeown-Longo, P.J.3
-
105
-
-
0030916129
-
Urokinase-type plasminogen activator receptors associate with β1 and β3 integrins of fibrosarcoma cells: Dependence on ECM components
-
Xue, W., Mizukami, I., Todd, R. F. 3rd, and Petty, H. R. (1997). Urokinase-type plasminogen activator receptors associate with β1 and β3 integrins of fibrosarcoma cells: dependence on ECM components. Cancer Res. 57, 1682-1689.
-
(1997)
Cancer Res.
, vol.57
, pp. 1682-1689
-
-
Xue, W.1
Mizukami, I.2
Todd R.F. III3
Petty, H.R.4
-
106
-
-
0029044627
-
Induction of carcinoma cell migration on vitronectin by NF-κB-dependent gene expression
-
Yebra, M., Filardo, E. J., Bayna, E. M., Kawahara, E., Becker, J. C., and Cheresh, D. A. (1995). Induction of carcinoma cell migration on vitronectin by NF-κB-dependent gene expression. Mol. Biol. Cell 6, 841-850.
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 841-850
-
-
Yebra, M.1
Filardo, E.J.2
Bayna, E.M.3
Kawahara, E.4
Becker, J.C.5
Cheresh, D.A.6
-
107
-
-
0029847191
-
Requirement of receptor-bound urokinase-type plasminogen activator for integrin αvβ5-directed cell migration
-
Yebra, M., Parry, G. C. N., Stromblad, S., Mackman, N., Rosenberg, S., Mueller, B. M., and Cheresh, D. A. (1996). Requirement of receptor-bound urokinase-type plasminogen activator for integrin αvβ5-directed cell migration. J. Biol. Chem. 271, 29393-29399.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29393-29399
-
-
Yebra, M.1
Parry, G.C.N.2
Stromblad, S.3
Mackman, N.4
Rosenberg, S.5
Mueller, B.M.6
Cheresh, D.A.7
-
108
-
-
0033542781
-
Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction
-
Yebra, M., Goretzki, L., Pfeifer, M., and Mueller, B. M. (1999). Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction. Exp. Cell Res. 250, 231-240.
-
(1999)
Exp. Cell Res.
, vol.250
, pp. 231-240
-
-
Yebra, M.1
Goretzki, L.2
Pfeifer, M.3
Mueller, B.M.4
|