Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598

Journal of Biological Chemistry

Volumn 272, Issue 45, 1997, Pages 28563-28567

  Koshelnick, Yuri ^a   Ehart, Monika ^a   Hufnagl, Peter ^a   Heinrich, Peter C ^b   Binder, Bernd R ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GLYCOSYLPHOSPHATIDYLINOSITOL; INTEGRIN; OLIGONUCLEOTIDE; PROTEIN KINASE P60; PROTEIN TYROSINE KINASE; STAT1 PROTEIN; UROKINASE;

ARTICLE; CELL CULTURE; DIMERIZATION; DNA BINDING; GENE ACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; KIDNEY EPITHELIUM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CENTRIFUGATION, DENSITY GRADIENT; CYTOSOL; DIMERIZATION; DNA; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; INTERFERON TYPE II; JANUS KINASE 1; KIDNEY NEOPLASMS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MEMBRANE GLYCOPROTEINS; NEOPLASM PROTEINS; PHOSPHORYLATION; PLASMINOGEN ACTIVATORS; PROTEIN-TYROSINE KINASES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED;

EID: 0030716909     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.45.28563     Document Type: Article

References (47)

1. Grondahl Hansen, J., Lund, L. R., Ralfkiaer, E., Ottevanger, V., and Dano, K. (1988) J. Invest. Dermatol. 90, 790-795
2. Schnaper, H. W., Barnathan, E. S., Mazar, A., Maheshwari, S., Ellis, S., Cortez, S. L., Baricos, W. H., and Kleinman, H. K. (1995) J. Cell. Physiol. 165, 107-118
3. Pepper, M. S., Vassalli, J. D., Montesano, R., and Orci, L. (1987) J. Cell Biol. 105, 2535-2541
4. Pepper, M. S., Sappino, A. P., Stocklin, R., Montesano, R., Orci, L., and Vassalli, J. D. (1993) J. Cell Biol. 122, 673-684
5. Bruckner, A., Filderman, A. E., Kirchheimer, J. C., Binder, B. R., and Remold, H. G. (1992) Cancer Res. 52, 3043-3047
6. Busso, N., Masur, S. K., Lazega, D., Waxman, S., and Ossowski, L. (1994) J. Cell Biol. 126, 259-270
7. Dumler, I., Petri, T., and Schleuning, W. D. (1993) FEBS Lett. 322, 37-40
8. Bohuslav, J., Horejsi, V., Hansmann, C., Stockl, J., Weidle, U. H., Majdic, O., Bartke, I., Knapp, W., and Stockinger, H. (1995) J. Exp. Med. 181, 1381-1390
9. Resnati, M., Guttinger, M., Valcamonica, S., Sidenius, N., Blasi, F., and Fazioli, F. (1996) EMBO J. 15, 1572-1582
10. Wei, Y., Lukashev, M., Simon, D. I., Bodary, S. C., Rosenberg, S., Doyle, M. V., and Chapman, H. A. (1996) Science 273, 1551-1555
11. Xue, W., Mizukami, I., Todd, R. F., and Petty, H. R. (1997) Cancer Res. 57, 1682-1689
12. Wang, N., Planus, E., Pouchelet, M., Fredberg, J. J., and Barlovatz Meimon, G. (1995) Am. J. Physiol. 268, C1062-C1066
13. Anichini, E., Fibbi, G., Pucci, M., Caldini, R., Chevanne, M., and Del Rosso, M. (1994) Exp. Cell Res. 213, 438-448
14. Li, C., Liu, J. N., and Gurewich, V. (1995) J. Biol. Chem. 270, 30282-30285
15. van den Berg, C. W., Cinek, T., Hallett, M. B., Horejsi, V., and Morgan, B. P. (1995) J. Cell Biol. 131, 669-677
16. Dumler, I., Petri, T., and Schleuning, W. D. (1994) FEBS Lett. 343, 103-106
17. Anderson, R. G. (1993) Curr. Opin. Cell Biol. 5, 647-652
18. Stahl, N., Boulton, T. G., Ip, N., Davis, S., and Yancopoulos, G. D. (1994) Braz. J. Med. Biol. Res. 27, 297-301
19. Ruthner, M., and Binder, B. R. (1994) Fibrinolysis 8, Suppl. 1, 97
20. Anderson, R. G. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10909-10913
21. Leaman, D. W., Pisharody, S., Flickinger, T. W., Commane, M. A., Schlessinger, J., Kerr, I. M., Levy, D. E., and Stark, G. R. (1996) Mol. Cell. Biol. 16, 369-375
22. Mineo, C., James, G. L., Smart, E. J., and Anderson, R. G. (1996) J. Biol. Chem. 271, 11930-11935
23. Liu, P., Ying, Y., Ko, Y. G., and Anderson, R. G. (1996) J. Biol. Chem. 271, 10299-10303
24. Lisanti, M. P., Scherer, P. E., Vidugiriene, J., Tang, Z., Hermanowski Vosatka, A., Tu, Y. H., Cook, R. F., and Sargiacomo, M. (1994) J. Cell Biol. 126, 111-126
25. Ruthner, M., Koshelnick, Y. R., Wijdenes, J., Heinrich, P. C., and Binder, B. R. (1995) Thromb. Haemostasis 73, 1132
26. Ruthner, M., Koshelnick, Y., and Binder, B. R. (1996) Fibrinolysis 10, 17
27. Geiger, M., Priglinger, U., Griffin, J. H., and Binder, B. R. (1991) J. Biol. Chem. 266, 11851-11857
28. Priglinger, U., Geiger, M., Bielek, E., Vanyek, E., and Binder, B. R. (1994) J. Biol. Chem. 269, 14705-14710
29. Brown, D. A., and Rose, J. K. (1992) Cell 68, 533-544
30. Laemmli, U. K. (1970) Nature 227, 680-685
31. Guschin, D., Rogers, N., Briscoe, J., Witthuhn, B., Watling, D., Horn, F., Pellegrini, S., Yasukawa, K., Heinrich, P., Stark, G. R., et al. (1995) EMBO J. 14, 1421-1429
32. Wang, Y., Morella, K. K., Ripperger, J., Lai, C. F., Gearing, D. P., Fey, G. H., Campos, S. P., and Baumann, H. (1995) Blood 86, 1671-1679
33. Falus, A. (1995) Immunol. Lett. 44, 221-223
34. Hirano, T., Matsuda, T., and Nakajima, K. (1994) Stem Cells (Dayton) 12, 262-277
35. Giorgetti Peraldi, S., Peyrade, F., Baron, V., and Van Obberghen, E. (1995) Eur. J. Biochem. 234, 656-660
36. Vignais, M. L., Sadowski, H. B., Watling, D., Rogers, N. C., and Gilman, M. (1996) Mol. Cell Biol. 16, 1759-1769
37. Yamamoto, H., Crow, M., Cheng, L., Lakatta, E., and Kinsella, J. (1996) Exp. Cell Res. 222, 125-130
38. Faris, M., Ensoli, B., Stahl, N., Yancopoulos, G., Nguyen, A., Wang, S., and Nel, A. E. (1996) AIDS 10, 369-378
39. Hemmann, U., Gerhartz, C., Heesel, B., Sasse, J., Kurapkat, G., Grotzinger, J., Wollmer, A., Zhong, Z., Darnell, J. E., Jr., Graeve, L., Heinrich, P. C., and Horn, F. (1996) J. Biol. Chem. 271, 12999-13007
40. Ernst, M., Gearing, D. P., and Dunn, A. R. (1994) EMBO J. 13, 1574-1584
41. Matsuda, T., Fukada, T., Takahashi Tezuka, M., Okuyama, Y., Fujitani, Y., Hanazono, Y., Hirai, H., and Hirano, T. (1995) J. Biol. Chem. 270, 11037-11039
42. Matsuda, T., Takahashi Tezuka, M., Fukada, T., Okuyama, Y., Fujitani, Y., Tsukada, S., Mano, H., Hirai, H., Witte, O. N., and Hirano, T. (1995) Blood 85, 627-633
43. Stahl, A., and Mueller, B. M. (1995) J. Cell Biol. 129, 335-344
44. Kirchheimer, J. C., Wojta, J., Christ, G., and Binder, B. R. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 5424-5428
45. Ruoslahti, E. (1996) Tumour Biol. 17, 117-124
46. Clark, E. A., and Brugge, J. S. (1995) Science 268, 233-239
47. Wei, Y., Waltz, D. A., Rao, N., Drummond, R. J., Rosenberg, S., and Chapman, H. A. (1994) J. Biol. Chem. 269, 32380-32388