A naturally occurring p73 mutation in a p73-p53 double-mutant lung cancer cell line encodes p73α protein with a dominant-negative function

Cancer Science

Volumn 94, Issue 8, 2003, Pages 718-724

  Huqun, A ^a   Endo, Yoshiyuki ^a   Xin, Hong ^a   Takahashi, Mitsu ^a   Nukiwa, Toshihiro ^a   Hagiwara, Koichi ^b  

^a TOHOKU UNIVERSITY   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; PROTEIN P53; PROTEIN P73; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; APOPTOSIS; CANCER CELL CULTURE; CELL GROWTH; COLONY FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA BINDING; DOMINANT GENE; GENE ACTIVITY; GENE DELETION; GENE MUTATION; GENE REPRESSION; GENETIC ANALYSIS; GENETIC CODE; GROWTH INHIBITION; HUMAN; HUMAN CELL; LUNG CANCER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; REVIEW; SEQUENCE HOMOLOGY; TRANSACTIVATION; WILD TYPE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BASE SEQUENCE; COLONY-FORMING UNITS ASSAY; DNA-BINDING PROTEINS; GENES, P53; GENES, TUMOR SUPPRESSOR; HUMANS; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; MUTATION; MUTATION, MISSENSE; NUCLEAR PROTEINS; RECOMBINANT PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0141702105     PISSN: 13479032     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2003.tb01508.x     Document Type: Review

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