The pH dependence of stability of the activation helix and the catalytic site of GART

Biophysical Chemistry

Volumn 105, Issue 2-3, 2003, Pages 279-291

  Morikis, Dimitrios ^a   Elcock, Adrian H ^b   Jennings, Patricia A ^c   McCammon, J Andrew ^c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Electrostatic calculations; GART; Glycinamide ribonucleotide transformylase; Helix coil transition; pKa; Poisson Boltzmann; Stability

Indexed keywords

ASPARTIC ACID; HISTIDINE; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE;

ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STABILITY; ENZYME STRUCTURE; IONIZATION; MOLECULAR INTERACTION; PH; PRIORITY JOURNAL;

EID: 0141676900     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-4622(03)00079-6     Document Type: Article

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