Catalytic mechanism of Escherichia coli glycinamide ribonucleotide transformylase probed by site-directed mutagenesis and pH-dependent studies

Biochemistry

Volumn 38, Issue 31, 1999, Pages 10024-10031

  Shim, Jae Hoon ^a   Benkovic, Stephen J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; APOENZYME; ASPARTIC ACID; DEUTERIUM; HISTIDINE; MUTANT PROTEIN; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME MECHANISM; ESCHERICHIA COLI; IONIZATION; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS;

BINDING SITES; CATALYSIS; DEUTERIUM OXIDE; ESCHERICHIA COLI; FOLIC ACID; HYDROGEN-ION CONCENTRATION; HYDROXYMETHYL AND FORMYL TRANSFERASES; KINETICS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; PLASMIDS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SOLVENTS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0001563512     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9904609     Document Type: Article

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