Double-blind, placebo-controlled study of INN 00835 (netamiftide) in the treatment of outpatients with major depression

International Clinical Psychopharmacology

Volumn 16, Issue 6, 2001, Pages 345-352

  Feighner, J P ^a   Ehrensing, R H ^a   Kastin, A J ^a   Patel, A ^a   Sverdlov, L ^a   Hlavka, J ^a   Abajian, H B ^a   Noble, J F ^a   Nicolau, Gabriela ^a  

^a Tetragenex Pharmaceuticals Inc   (United States)

Author keywords

Antidepressant; Clinical trial; Netamiftide; Peptide

Indexed keywords

4 FLUOROPHENYL 4 HYDROXYPROLYLARGINYLGLYCYLTRYPTOPHANAMIDE; ANTIDEPRESSANT AGENT; NETAMIFTIDE; PLACEBO; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOSE CALCULATION; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG SAFETY; FEMALE; GASTROINTESTINAL SYMPTOM; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PSYCHOMETRY; RATING SCALE; SELF CONCEPT; SOMNOLENCE; TREATMENT OUTCOME; VERTIGO;

EID: 0034764916     PISSN: 02681315     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004850-200111000-00005     Document Type: Article

References (18)

1. Melanocyte-stimulating hormone-release inhibiting hormone as an antidepressant: A pilot study
2. Dose-related biphasic effect of prolyl-leucyl-glycinamide (MIF-1) in depression
3. Improvements in major depression after low subcutaneous doses of MIF-1
4. A double-blind, placebo-controlled; efficacy, safety and pharmacokinetic study of INN 00835, a novel antidepressant peptide, in the treatment of major depression
5. Four different approaches to separate drug-treated population from placebo after treatment with a new pentapeptide antidepressant
6. Clinical pharmacokinetic studies with the antidepressant pentapeptide: INN 00835
7. Chemistry and pharmacology of novel antidepressant peptides
8. Enkephalin and other peptides reduce passiveness
9. Effects of MIF-1 and three related peptides on reserpine-induced hypothermia in mice
10. Pharmacokinetics and tissue distribution of a novel antidepressant, INN 00835 following intravenous and subcutaneous administration to rats
11. Metabolism of an antidepressant pentapeptide INN 00835 in liver, intestinal and brain preparations
12. Tricyclic antidepressant concentrations in plasma: An estimate of their sensitivity and specificity as a predictor of response
13. MIF-1 is active in a chronic stress animal model of depression
14. Automated on-line SPE/LC/MS quantitation of INN 00835, a synthetic pentapeptide, in human plasma
15. Rapid clinical effectiveness of MIF-1 in the treatment of major depressive illness
16. Mechanism of action of prolyl-L-leucyl-glycinamide and its effect on Parkinson's disease