Potentiation of diclofenac-induced anti-inflammatory response by aminoguanidine in carrageenan-induced acute inflammation in rats: The role of nitric oxide

Inflammation Research

Volumn 52, Issue 9, 2003, Pages 378-382

  Al Majed, A A ^a   Khattab, M ^a   Raza, M ^a   Al Shabanah, O A ^a   Mostafa, A M ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Aminoguanidine; Carrageenan; Diclofenac; Inflammation

Indexed keywords

AMINOGUANIDINE; CARRAGEENAN; DICLOFENAC; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM;

ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG POTENTIATION; EXPERIMENTAL MODEL; INFLAMMATION; INHIBITION KINETICS; MALE; NONHUMAN; PAW EDEMA; RAT;

ACUTE DISEASE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; DICLOFENAC; DRUG SYNERGISM; EDEMA; GUANIDINES; INFLAMMATION; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITROPRUSSIDE; RATS; RATS, WISTAR; TIME FACTORS;

EID: 0141630497     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00011-003-1189-1     Document Type: Article

References (44)

1. Vinegar R, Schreiber W, Hugo R. Biphasic development of carrageenan edema in rats. J Pharmacol Exp Ther 1969; 166: 96-103.
2. Salvemini D, Wang Z, Wyatt PS, Bourdon DM, Marino MH, Manning PT et al. Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br J Pharmacol 1996; 118: 829-38.
3. Di Rosa M, Giroud JP, Willoughby DA. Studies of mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J Pathol 1971; 104: 15-29.
4. Di Rosa M, Willoughby DA. Screen for anti-inflammatory drugs. J Pharm Pharmacol 1971; 23: 297-300.
5. Seibert K, Zhang Y, Leahy K, Hauser S, Masferrer J, Perkins W et al. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci USA 1994; 91: 12013-17.
6. Lain HH, Hanley DF, Trapp BD, Saito S, Raja S, Dawson TM et al. Induction of spinal cord neuronal nitric oxide synthase (NOS) after formalin injection in the rat hind paw. Neurosci Lett 1996; 210: 201-4.
7. Garthwaite J, Charles SL, Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 1988; 336: 385-8.
8. D'Acquisto F, Sautebin L, Iuvone T, Di Rosa M, Carnuccio R. Prostaglandins prevent inducible nitric oxide synthase protein expression by inhibiting nuclear factor-kappa-B activation in J774 macrophages. FEBS Lett 1998; 440: 76-80.
9. Lowenstein CJ, Alley EW, Raval P, Snowman AM, Snyder SH, Russell SW et al. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. Proc Natl Acad Sci USA 1993; 90: 9730-4.
10. Goldring CE, Narayanan R, Lagadec P, Jeannin JF. Transcriptional inhibition of the inducible nitric oxide synthase gene by competitive binding of NF-kappa B/Rel proteins. Biochem Biophys Res Commun 1995; 209: 73-9.
11. Amoah-Apraku B, Chandler LJ, Harrison JK, Tang SS, Ingel-finger JR, Guzman NJ. NF-kappa B and transcriptional control of renal epithelial-inducible nitric oxide synthase. Kidney Int 1995; 48: 674-82.
12. Handy RL, Moore PK. A comparison of the effects of L-NAME, 7-NI and L-NIL on carrageenan- induced hindpaw edema and NOS activity. Br J Pharmacol 1998; 123: 1119-26.
13. Osborne MG, Coderre TJ. Effects of intrathecal administration of nitric oxide synthase inhibitors on carrageenan-induced thermal hyperalgesia. Br J Pharmacol 1999; 126: 1840-6.
14. Gühring H, Tegeder I, Lötsch J, Pahl A, Werner U, Reeh PW et al. Role of nitric oxide in zymosan induced paw inflammation and thermal hyperalgesia. Inflamm Res 2001; 50: 83-8.
15. Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathology and pharmacology. Pharmacol Rev 1991; 43: 109-42.
16. Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993; 329: 2002-12.
17. 2 release from the hypothalamus. Proc Natl Acad Sci USA 1992; 89: 11543-6.
18. Salvemini D, Misko TP, Seibert K, Masferrer JL, Currie MG, Needleman P. Nitric oxide activates cyclooxygenase enzymes. Proc Natl Acad Sci USA 1993; 90: 7240-4.
19. 2 production by vascular smooth muscle cells. Biochem Biophys Res Commun 1993; 194: 420-4.
20. Corbett JA, Kwon G, Turk J, Mcdaniel ML. IL-1β induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of langerhans: activation of cyclooxygenase by nitric oxide. Biochemistry 1993; 32: 13767-70.
21. Davidge ST, Baker PN, McLaughlin MK, Roberts JM. Nitric oxide produced by endothelial cells increases production of eicosanoids through activation of prostaglandin H synthase. Circ Res 1995; 77: 274-83.
22. Salvemini D, Seibert K, Masferrer JL, Misko TP, Currie MG, Needleman P. Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J Clin Invest 1994; 93: 1940-7.
23. Sautebin L, Di Rosa M. Nitric oxide modulates prostacyclin biosynthesis in the lung of endotoxin-treated rats. Eur J Pharmacol 1994; 262: 193-6.
24. Salvemini D, Manning PT, Zweifel BS, Seibert K, Connor J, Currie MG et al. Dual inhibition of nitric oxide and prostaglandin production contributes to the anti-inflammatory properties of nitric oxide synthase inhibitors. J Clin Invest 1995a; 96: 301-8.
25. Salvemini D, Settle SL, Masferrer JL, Currie MG, Needleman P. Regulation of prostaglandin production by nitric oxide; an in vivo analysis. Br J Pharmacol 1995b; 114: 1171-8.
26. Sautebin L, Ialenti A, Ianaro A, Di Rosa M. Modulation by nitric oxide of prostaglandin biosynthesis in the rat. Br J Pharmacol 1995; 114: 323-8.
27. Hajjar DP, Lander HM, Pearce FS, Upmacis RK, Pomerantz KB. Nitric oxide enhances prostaglandin H synthase activity by a heme-independent mechanism:evidence implicating nitrosothiols. J Am Chem Soc 1995; 117: 3340-6.
28. Vinegar R, Turuax JF, Selph JL, Johnston PR, Venable AL, Mckenzie KK. Pathway to carrageenan-induced inflammation in the hind limb of the rat. Fed Proc 1987; 46: 118-26.
29. Raza M, Dhariwal MAH, Ageel AM, Qureshi S. Evaluation of the antiinflammatory activity of sodium valproate in rats and mice. Gen Pharmacol 1996; 27: 1395-400.
30. Raza M, Ahmad M, Gado A, Al-Shabanah OA. A comparison of hepatoprotective activities of aminoguanidine and N-acetylcysteine in rat against the toxic damage induced by azathioprine. Comperative Biochemistry and Physiology part C 2003; 134: 451-56
31. Leyck S, Parnham MJ. Acute antiinflammatory and gastric effects of the seleno-organic compound ebselen. Agents Actions 1990; 30: 426-31
32. Seitz S, Kretz-Rommel A, Oude Elferink RP, Boelsterli UA. Selective protein adduct formation of diclofenac glucuronide is critically dependent on the rat canalicular conjugate export pump (Mrp2). Chem Res Toxicol 1998; 11: 513-9
33. Wen Zhu and Fung PCW. The roles played by crucial free radicals like lipid free radicals, nitric oxide, and enzymes NOS and NADPH in CC14-induced acute liver injury of mice. Free Radical Biology & Medicine, 2000; 29: 870-80.
34. Winter CA, Risley EA, Nuss GW. Carrageenan-induced edema in hind paw of the rat as an assay for antiinflammatory drugs. Proc. Soc Exp Biol Med 1962; 111: 544-7.
35. Gürsoy A, Eroglu L, Ulutin S, Tasyürek M, Fessi H, Puisieux F et al. Evaluation of indomethacin nanocapsules for their physical stability and inhibitory activity on inflammation and platelet aggregation. Int J Pharm 1989; 52: 101-8.
36. Gad MZ, Khattab M. Modulation of nitric oxide synthesis in inflammation. Relationship to oxygen-derived free radicals and prostaglandin synthesis. Arzneimittelforschung 2000; 50: 449-55.
37. Posadas I, Terencio MC, Guillen I, Ferrandiz ML, Coloma J, Paya M et al. Co-regulation between cyclo-oxygenase-2 and inducible nitric oxide synthase expression in the time-course of murine inflammation. Naunyn Schmiedebergs Arch Pharmacol 2000; 361: 98-106.
38. Nogawa S, Forster C, Zhang F, Nagayama M, Ross ME, Iadecola C. Interaction between inducible nitric oxide synthase and cyclooxygenase-2 after cerebral ischemia. Proc Natl Acad Sci USA 1998 1; 95: 10966-71.
39. Xie WL, Chipman JG, Robertson DL, Erikson RL. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 1991; 88: 2692-6.
40. Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van de Putte LBA et al. Cyclooxygenase in biology and disease. FASEB J 1998; 12: 1063-73.
41. Cryer B, Feldman M. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal antiinflammatory drugs. Am J Med 1998; 104: 413-21.
42. Warren JB, Coughlan ML, Williams TJ. Endotoxin-induced vasodilation in anaesthetized rat skin involves nitric oxide and prostaglandin synthesis. Br J Pharmacol 1992; 106: 953-7.
43. Feldman M, McMahon AT. Do cyclooxygenase-2 inhibitors provide benefits similar to those of traditional nonsteroidal antiinflammatory drugs, with less gastrointestinal toxicity? Ann Intern Med 2000; 132: 134-43.
44. Wolfe MM, Lichtenstein DR, Singh G. Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs. N Engl J Med 1999; 340: 1888-99.