Glutathione

ANZ Journal of Surgery

Volumn 73, Issue 7, 2003, Pages 517-522

  Jefferies, Heather ^a   Coster, Jane ^a   Khalil, Alizan ^a   Bot, Joan ^a   McCauley, Rosalie D ^a,b   Hall, John C ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b ROYAL PERTH HOSPITAL   (Australia)

Author keywords

Glutathione; Inflammatory bowel disease; Ischaemia reperfusion injury; Oncology; Sepsis

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; REACTIVE OXYGEN METABOLITE; SODIUM SELENITE;

ALLELE; APOPTOSIS; CROHN DISEASE; DETOXIFICATION; DNA POLYMORPHISM; GENE EXPRESSION REGULATION; HUMAN; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PROTEIN FUNCTION; PROTEIN METABOLISM; REDUCTION; REVIEW; SEPSIS; ULCERATIVE COLITIS;

GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HUMANS; INFLAMMATORY BOWEL DISEASES; NEOPLASMS; OXIDATION-REDUCTION; REPERFUSION INJURY; SEPSIS;

EID: 0043234468     PISSN: 14451433     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1445-1433.2003.02682.x     Document Type: Review

References (58)

1. Mates M. Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology 2000; 153: 83-104.
2. Locigno R, Castronovo V. Reduced glutathione system: Role in cancer development, prevention and treatment. Int. J. Oncol. 2001; 19: 221-36.
3. Paolicchi A, Dominici S, Pieri L, Maellaro E, Pompella A. Glutathione catabolism as a signaling mechanism. Biochem. Pharmacol. 2002; 64: 1027-35.
4. Flagg EW, Coates RJ, Eley JW et al. Dietary glutathione intake in humans and the relationship between intake and plasma total glutathione level. Nutr. Cancer 1994; 21: 33-46.
5. Iantomasi T, Favilli F, Marraccini P, Magaldi T, Bruni P, Vincenzini MT. Glutathione transport system in human small intestine epithelial cells. Biochim. Biophys. Acta 1997; 1330: 274-83.
6. Roth E, Oehler R, Manhart N et al. Regulative potential of glutamine - relation to glutathione metabolism. Nutrition 2002; 18: 217-21.
7. Mates JM, Perez-Gomez C, Nunez de Castro I, Asenjo M, Marquez J. Glutamine and its relationship with intracellular redox status, oxidative stress and cell proliferation/death. Int. J. Biochem. Cell Biol. 2002; 34: 439-58.
8. Rennie MJ, Bowtell JL, Bruce M, Khogali SE. Interaction between glutamine availability and metabolism of glycogen, tricarboxylic acid cycle intermediates and glutathione. J. Nutr. 2001; 131: 2488S-90S.
9. Hayes JD, McLellen LI. Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. Free Rad. Res. 1999; 31: 273-300.
10. Berlett BS, Stadtman ER. Protein oxidation in aging, disease, and oxidative stress. J. Biol. Chem. 1997; 272: 20313-6.
11. Beckman KB, Ames BN. Oxidative decay of DNA. J. Biol. Chem. 1997; 272: 19633-6.
12. Arthur JR. The glutathione peroxidases. Cell Mol. Life Sci. 2000; 57: 1825-35.
13. Strange RC, Spiteri MA, Ramachandran S, Fryer AA. Glutathione-S-transferase family of enzymes. Mutat. Res. 2001; 482: 21-6.
14. Whitfield JB. Gamma glutamyl transferase. Crit. Rev. Clin. Lab. Sci. 2001; 38: 263-355.
15. Heales SJ, Bolanos JP. Impairment of brain mitochondrial function by reactive nitrogen species: The role of glutathione in dictating susceptibility. Neurochem. Int. 2002; 40: 469-74.
16. Hancock JT, Desikan R, Neill SJ. Does the redox status of cytochrome C act as a fail-safe mechanism in the regulation of programmed cell death? Free Radic. Biol. Med. 2001; 31: 697-703.
17. Anaya-Prado R, Toledo-Pereyra LH, Lentsch AB, Ward PA. Ischemia/reperfusion injury. J. Surg. Res. 2002; 105: 248-58.
18. Parks DA, Granger DN. Contributions of ischemia and reperfusion to mucosal lesion formation. Am. J. Physiol. 1986; 250: G749-53.
19. Carden DL, Granger DN. Pathophysiology of ischaemia-reperfusion injury. J. Pathol. 2000; 190: 255-66.
20. Wink DA, Mitchell JB. Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide. Free Radic. Biol. Med. 1998; 25: 434-56.
21. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994; 76: 301-14.
22. Nakamura S, Kugiyama K, Sugiyama S et al. Polymorphism in the 5′-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction. Circulation 2002; 105: 2968-73.
23. Chen J, Henderson GI, Freeman GL. Role of 4-hydroxynonenal in modification of cytochrome c oxidase in ischemia/reperfused rat heart. J. Mol. Cell Cardiol. 2001; 33: 1919-27.
24. Anderson MF, Sims NR. The effects of focal ischemia and reperfusion on the glutathione content of mitochondria from rat brain subregions. J. Neurochem. 2002; 81: 541-9.
25. Crack PJ, Taylor JM, Flentjar NJ et al. Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury. J. Neurochem. 2001; 78: 1389-99.
26. Ishibashi N, Prokopenko O, Reuhl KR, Mirochnitchenko O. Inflammatory response and glutathione peroxidase in a model of stroke. J. Immunol. 2002; 168: 1926-33.
27. St Peter SD, Imber CJ, Jones DC et al. Genetic determinants of delayed graft function after kidney transplantation. Transplantation 2002; 74: 809-13.
28. Khurana S, Corbally MT, Manning F, Armenise T, Kierce B, Kilty C. Glutathione S-transferase: A potential new marker of intestinal ischemia. J. Pediatr. Surg. 2002; 37: 1543-8.
29. Gartner R, Albrich W, Angstwurm MW. The effect of a selenium supplementation on the outcome of patients with severe systemic inflammation, burn and trauma. Biofactors 2001; 14: 199-204.
30. Angstwurm MW, Schottdorf J, Schopohl J, Gaertner R. Selenium replacement in patients with severe systemic inflammatory response syndrome improves clinical outcome. Crit. Care Med. 1999; 27: 1807-13.
31. Panes J. Inflammatory bowel disease: pathogenesis and targets for therapeutic interventions. Acta Physiol. Scand. 2001; 173: 159-65.
32. Laroux FS, Grisham MB. Immunological basis of inflammatory bowel disease: Role of the microcirculation. Microcirculation 2001; 8: 283-301.
33. Nieto N, Torres MI, Fernandez MI et al. Experimental ulcerative colitis impairs antioxidant defense system in rat intestine. Dig. Dis. Sci. 2000; 45: 1820-7.
34. Ardite E, Sans M, Panes J, Romero FJ, Pique JM, Fernandez-Checa JC. Replenishment of glutathione levels improves mucosal function in experimental acute colitis. Lab. Invest. 2000; 80: 735-44.
35. Tham DM, Whitin JC, Cohen HJ. Increased expression of extracellular glutathione peroxidase in mice with dextran sodium sulfate-induced experimental colitis. Pediatr. Res. 2002; 51: 641-6.
36. Sido B, Hack V, Hochlehnert A, Lipps H, Herfarth C, Droge W. Impairment of intestinal glutathione synthesis in patients with inflammatory bowel disease. Gut 1998; 42: 485-92.
37. Bhaskar L, Ramakrishna BS, Balasubramanian KA. Colonic mucosal antioxidant enzymes and lipid peroxide levels in normal subjects and patients with ulcerative colitis. J. Gastroenterol. Hepatol. 1995; 10: 140-3.
38. Holmes EW, Yong SL, Eiznhamer D, Keshavarzian A. Glutathione content of colonic mucosa: Evidence for oxidative damage in active ulcerative colitis. Dig. Dis. Sci. 1998; 43: 1088-95.
39. Innocenti F, Ratain MJ. Update on pharmacogenetics in cancer chemotherapy. Eur. J. Cancer 2002; 38: 639-44.
40. Brookes AJ. The essence of SNPs. Gene 1999; 234: 177-86.
41. Engel LS, Taioli E, Pfeiffer R et al. Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: A HuGE review. Am. J. Epidemiol. 2002; 156: 95-109.
42. Pearson WR, Vorachek WR, Xu SJ et al. Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome lpl3. Am. J. Hum. Genet. 1993; 53: 220-33.
43. McWilliams JE, Sanderson BJ, Harris EL, Richert-Boe KE, Henner WD. Glutathione S-transferase M1 (GSTM1) deficiency and lung cancer risk. Cancer Epidemiol. Biomarkers Prev. 1995; 4: 589-94.
44. Zhong S, Wyllie AH, Barnes D. Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer. Carcinogenesis 1993; 14: 1821-4.
45. Sprenger R, Schlagenhaufer R, Kert R. Characterization of the glutathione S-transferase GSTT1 deletion: Discrimination of all genotypes by polymerase chain reaction indicates a trimodular genotype-phenotype correlation. Pharmacogenetics 2000; 10: 557-65.
46. Chenevix-Trench G, Young J, Coggan M, Board P. Glutathione S-transferase M1 and T1 polymorphisms: Susceptibility to colon cancer and age of onset. Carcinogenesis 1995; 16: 1655-7.
47. Elexpuru-Camiruaga J, Buxton N, Kandula V et al. Susceptibility to astrocytoma and meningioma: Influence of allelism at glutathione S-transferase. (GSTT1 and GSTM1) and cytochrome P-450 (CYP2D6) loci. Cancer Res. 1995; 55: 4237-9.
48. Chen H, Sandler DP, Taylor JA et al. Increased risk for myelodysplastic syndromes in individuals with glutathione transferase the (GSTT1) gene defect. Lancet 1996; 347: 295-7.
49. Hayes JD, McMahon M. Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention. Cancer Lett. 2001; 174: 103-13.
50. Afaq F, Mukhtar H. Effects of solar radiation on cutaneous detoxification pathways. J. Photochem. Photobiol. B. 2001; 63: 61-9.
51. Kiss C, Li J, Szeles A et al. Assignment of the ARHA and GPX1 genes to human chromosome bands 3p21.3 by in situ hybridization and with somatic cell hybrids. Cytogenet. Cell Genet. 1997; 79: 228-30.
52. Moscow JA, Morrow CS, He R, Mullenbach GT, Cowan KH. Structure and function of the 5′-flanking sequence of the human cytosolic selenium-dependent glutathione peroxidase gene (hgpx1). J. Biol. Chem. 1992; 267: 5949-58.
53. Moscow JA, Schmidt L, Ingram DT, Gnarra J, Johnson B, Cowan KH. Loss of heterozygosity of the human cytosolic glutathione peroxidase I gene in lung cancer. Carcinogenesis 1994; 15: 2769-73.
54. Lampe JW, Peterson S. Brassica, biotransformation and cancer risk: Genetic polymorphisms alter the preventive effects of cruciferous vegetables. J. Nutr. 2002; 132: 2991-4.
55. Steinkellner H, Rabot S, Freywald C et al. Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens. Mutat. Res. 2001; 480: 285-97.
56. Simopoulos AP. The Mediterranean diets. What is so special about the diet of Greece? The scientific evidence. J. Nutr. 2001; 131: 3065S-73S.
57. McCarver DG, Hines RN. The ontogeny of human drug-metabolizing enzymes: Phase II conjugation enzymes and regulatory mechanisms. J. Pharmacol. Exp. Ther. 2002; 300: 361-6.
58. Perek N, Denoyer D. The multidrug resistance mechanisms and their interactions with the radiopharmaceutical probes used for an in vivo detection. Curr. Drug Metab. 2002; 3: 97-113.