The Mediterranean diets: What is so special about the diet of Greece? The scientific evidence

Journal of Nutrition

Volumn 131, Issue 11 SUPPL., 2001, Pages

  Simopoulos, A P ^a  

^a Center for Nutrition Genetics & Health   (United States)

Author keywords

(n 3) fatty acids; (n 6) fatty acids; Antioxidants; Cancer; Diet of Crete; Wild plants

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; ESSENTIAL FATTY ACID; GLUTATHIONE; OLIVE OIL; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; SELENIUM;

BREAST CANCER; CANCER PREVENTION; CANCER RISK; CONFERENCE PAPER; DIET; FAT INTAKE; FOOD INTAKE; FRUIT; GEOGRAPHY; GREECE; HUMAN; ISCHEMIC HEART DISEASE; MORTALITY; RISK ASSESSMENT; VEGETABLE;

OLEACEAE;

EID: 0035165044     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/131.11.3065s     Document Type: Conference Paper

References (114)

1. Genetic variation and nutrition
2. Genetic variation and dietary response
3. Evolutionary aspects of nutrition and health: Diet, exercise, genetics and chronic disease
4. Omega-3 fatty acids in health and disease and in growth and development
5. Paleolithic nutrition. A consideration of its nature and current implications
6. Stone agers in the fast lane: Chronic degenerative diseases in evolutionary perspective
7. Dietary intake of long-chain polyunsaturated fatty acids during the Paleolithic
8. Overview of evolutionary aspects of ω3 fatty acids in the diet
9. Polyunsaturated fatty acids in the food chain in Europe
10. Polyunsaturated fatty acids in the food chain in Japan
11. Genetic variation and evolutionary aspects of diet
12. Evolutionary aspects of omega-3 fatty acids in the food supply
13. Nutrition and fitness
14. Nutrition and fitness. Diet, genes, physical activity and health
15. Nutrition and fitness. Metabolic studies in health and disease
16. Evolutionary aspects of diet and essential fatty acids
17. Mediterranean diets
18. Coronary heart disease in seven countries
19. Mediterranean alpha-linolenic acid-rich diet in the secondary prevention of coronary heart disease
20. Cretan Mediterranean diet for prevention of coronary heart disease
21. Mediterranean dietary pattern in a randomized trial Prolonged survival and possible reduced cancer rate
22. Modified Cretan Mediterranean diet in the prevention of coronary heart disease and cancer
23. Randomised controlled trial of cardioprotective diet in patients with recent acute myocardial infarction: Results of a one year follow-up
24. Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: The Indian experiment of infarct survival-4
25. Health effects of ω3 polyunsaturated fatty acids in seafoods
26. Effects of fatty acids and lipids in health and disease
27. Fatty acids and lipids: Biological aspects
28. Proceedings of the 2nd Congress of ISSFAL on fatty acids and lipids from cell biology to human disease
29. Proceedings of the 3rd Congress of ISSFAL on fatty acids and lipids from cell biology to human disease
30. Purslane: A terrestrial source of omega-3 fatty acids
31. Common purslane: A source of omega-3 fatty acids and antioxidants
32. Purslane in human nutrition and its potential for world agriculture
33. (n-3) Fatty acids in eggs from range-fed Greek chickens
34. Egg yolk as a source of long-chain polyunsaturated fatty acids in infant feeding
35. Trans-fatty-acid content of common foods
36. Serum lipids in elderly men in Crete and The Netherlands
37. Influence of long-term diet modification on platelet function and composition in Moselle farmers
38. Antioxidant vitamins and β-carotene in disease prevention
39. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in The Netherlands
40. Isoflavonoids and lignans in legumes - Nutritional and health aspects in humans
41. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation
42. Mechanisms of action in antioxidants as exemplified in vegetables, tomatoes and tea
43. Effect of changes in fat, fish and fibre intakes on death and myocardial reinfarction
44. Dietary supplementation with n-3 polyunsaturated fatty acids vitamin E after myocardial infarction. Results of the GISSI-Prevenzione trial
45. Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants
46. Safety and efficacy of ω-3 fatty acids in the nutrition of very low birth weight infants. Soy oil and marine oil supplementation of formula
47. Breast-feeding and optimal visual development
48. Cardiovascular effects of n-3 fatty acids
49. ω-3 Fatty acids in the prevention-management of cardiovascular disease
50. Essential fatty acids in health and chronic disease
51. Essentiality of and recommended dietary intakes for omega-6 and omega-3 fatty acids
52. Cancer mortality in Europe, 1990-1992
53. Polyunsaturated fatty acids and epidermal growth factor receptor/mitogen-activated protein kinase signaling in mammary cancer
54. Dietary ω3 fatty acids and cancer: An overview
55. ω3 Fatty acid diet effects on tumorigenesis in experimental animals
56. Fatty acids: Inhibition
57. Breast cancer in Greenland - Selected epidemiological, clinical and histological features
58. Low alpha-linolenic acid content of adipose breast tissue is associated with an increased risk of breast cancer
59. Fatty fish consumption and risk of prostate cancer
60. Association of enhanced cyclooxygenase-2 expression with possible local immunosuppression in human colorectal carcinomas
61. Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells
62. Docosahexaenoic acid, a peroxisome proliferator-activated receptor-alpha ligand, induces apoptosis in vascular smooth muscle cells by stimulation of p38 mitogen-activated protein kinase
63. 15-Hydroxyeicosatrienoic acid (15-HETrE) suppresses epidermal hyperproliferation via the modulation of nuclear transcription factor (AP-1) and apoptosis
64. Cell cycle arrest and apoptosis of melanoma cells by docosahexaenoic association with decreased pRb phosphorylation
65. Effects of reduced dietary linoleic acid intake, alone or combined with algal source of docosahexaenoic acid, on MDA-MB-231 breast cancer growth and apoptosis in nude mice
66. Effects of eicosapentaenoic and docosahexaenoic acids dietary supplementation on cell proliferation and apoptosis in rat colonic mucosa
67. The effect of polyunsaturated fatty acids on the progress of cachexia in patients with pancreatic cancer
68. Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: A randomized control trial
69. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin: A randomized controlled trial
70. Study of prediagnostic selenium levels in toenails and the risk of advanced prostate cancer
71. The chemoprevention role of selenium carcinogenesis
72. Effects of stilbene components of the roots of Polygonum cuspidatum Sieb. et Zucc. on lipid metabolism
73. Effects of stilbenes on arachidonate metabolism in leukocytes
74. Effects of stilbene derivative on arachidonate metabolism in leukocytes
75. Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes
76. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
77. Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor
78. 2 phase transition
79. Resveratrol, a remarkable inhibitor of ribonucleotide reductase
80. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cell
81. DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia
82. Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells
83. Resveratrol, a natural product present in wine, decreases tumor growth in rat tumor model
84. Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice
85. Oral administration of glutathione (GSH) increases plasma GSH concentrations in humans
86. Glutathione in foods listed in the National Cancer Institute's Health Habits and History Food Frequency Questionnaire
87. Nutrient sources in the American diet: Quantitative data from the NHANES II survey I. Vitamins and minerals
88. Nutrient sources in the American diet: Quantitative data from the NHANES II survey II. Macronutrients and fats
89. Glutathione: General review of mechanism of action
90. Perspectives in cancer research. Chemoprevention of cancer
91. Ascorbate is an outstanding antioxidant in human blood plasma
92. Antioxidant micronutrients in immune responses
93. Antioxidant defenses and lipid peroxidation in human blood
94. Inhibition of radiation-induced DNA-protein cross-link repair by glutathione depletion with L-buthionine sulfoximine
95. Glutaredoxin
96. Reversal of age-associated decline in immune responsiveness by dietary glutathione supplementation in mice
97. Systemic glutathione deficiency in symptom-free HIV-seropositive individuals
98. Plasma total glutathione in humans and its association with demographic and health-related factors
99. Vitamin E: Interactions with free radicals and ascorbate
100. Glutathione metabolism and possible biological roles in the higher plant
101. Aspects of glutathione function and metabolism in plants
102. Proceedings 1989 Annual Symposium South ASPP: Glutathione synthesis and function in higher plants
103. Diurnal variation of glutathione levels in tomato seedlings
104. Diurnal changes in the glutathione content of spruce needles (Picea abies L.)
105. Control of wild carrot somatic embryo development by antioxidants
106. Sulphate-induced accumulation of glutathione and frost-tolerance of spinach leaf tissue
107. Chilling-enhanced photooxidation. The peroxidative destruction of lipids during chilling injury to photosynthesis and ultrastructure
108. The Mediterranean food guide. Greek column rather than an Egyptian pyramid