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Volumn 5, Issue 11, 2003, Pages 939-946

A DNA vaccine encoding the outer surface protein C from Borrelia burgdorferi is able to induce protective immune responses

Author keywords

DNA vaccines; Gene gun technique; Lyme borreliosis

Indexed keywords

DNA VACCINE; OUTER SURFACE PROTEIN C; PLASMID DNA; RECOMBINANT PROTEIN; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

EID: 0043198261     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(03)00182-5     Document Type: Article
Times cited : (39)

References (33)
  • 1
    • 0030937831 scopus 로고    scopus 로고
    • Lyme disease: A review of aspects of its immunology and immunopathogenesis
    • Sigal L.H. Lyme disease: a review of aspects of its immunology and immunopathogenesis. Annu. Rev. Immunol. 15:1997;63-92.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 63-92
    • Sigal, L.H.1
  • 3
    • 0030025949 scopus 로고    scopus 로고
    • Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine
    • de Silva A.M., Telford S.R., Brunet L.R., Barthold S.W., Fikrig E. Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine. J. Exp. M. 1:1996;271-275.
    • (1996) J. Exp. M , vol.1 , pp. 271-275
    • De Silva, A.M.1    Telford, S.R.2    Brunet, L.R.3    Barthold, S.W.4    Fikrig, E.5
  • 4
    • 0027495494 scopus 로고
    • Passive immunizing activity of sera from mice infected with Borrelia burgdorferi
    • Barthold S.W., Bockenstedt L.K. Passive immunizing activity of sera from mice infected with Borrelia burgdorferi. Infect. Immun. 11:1993;4696-4702.
    • (1993) Infect. Immun. , vol.11 , pp. 4696-4702
    • Barthold, S.W.1    Bockenstedt, L.K.2
  • 5
    • 0028200919 scopus 로고
    • Tick transmission of Borrelia burgdorferi to inbred strains of mice induces an antibody response to P39 but not to outer surface protein A
    • (published erratum appears in Infect. Immun. 63 [3] [1995] 1146)
    • Golde W.T., Kappel K.J., Dequesne G., Feron C., Plainchamp D., Capiau C., Lobet Y. Tick transmission of Borrelia burgdorferi to inbred strains of mice induces an antibody response to P39 but not to outer surface protein A. Infect. Immun. 6:1994;2625-2627. (published erratum appears in Infect. Immun. 63 [3] [1995] 1146).
    • (1994) Infect. Immun. , vol.6 , pp. 2625-2627
    • Golde, W.T.1    Kappel, K.J.2    Dequesne, G.3    Feron, C.4    Plainchamp, D.5    Capiau, C.6    Lobet, Y.7
  • 6
    • 0032950531 scopus 로고    scopus 로고
    • Influence of outer surface protein A antibody on Borrelia burgdorferi within feeding ticks
    • de Silva A.M., Zeidner N.S., Zhang Y., Dolan M.C., Piesman J., Fikrig E. Influence of outer surface protein A antibody on Borrelia burgdorferi within feeding ticks. Infect. Immun. 1:1999;30-35.
    • (1999) Infect. Immun. , vol.1 , pp. 30-35
    • De Silva, A.M.1    Zeidner, N.S.2    Zhang, Y.3    Dolan, M.C.4    Piesman, J.5    Fikrig, E.6
  • 7
    • 0030048119 scopus 로고    scopus 로고
    • Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: Exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease
    • Montgomery R.R., Malawista S.E., Feen K.J., Bockenstedt L.K. Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease. J. Exp. M. 1:1996;261-269.
    • (1996) J. Exp. M , vol.1 , pp. 261-269
    • Montgomery, R.R.1    Malawista, S.E.2    Feen, K.J.3    Bockenstedt, L.K.4
  • 8
    • 0032967572 scopus 로고    scopus 로고
    • Effects of environmental pH on membrane proteins in Borrelia burgdorferi
    • Carroll J.A., Garon C.F., Schwan T.G. Effects of environmental pH on membrane proteins in Borrelia burgdorferi. Infect. Immun. 7:1999;3181-3187.
    • (1999) Infect. Immun. , vol.7 , pp. 3181-3187
    • Carroll, J.A.1    Garon, C.F.2    Schwan, T.G.3
  • 10
    • 0029948977 scopus 로고    scopus 로고
    • Outer surface protein C (OspC), but not P39, is a protective immunogen against a tick-transmitted Borrelia burgdorferi challenge: Evidence for a conformational protective epitope in OspC
    • Gilmore R.D. Jr, Kappel K.J., Dolan M.C., Burkot T.R., Johnson B.J. Outer surface protein C (OspC), but not P39, is a protective immunogen against a tick-transmitted Borrelia burgdorferi challenge: evidence for a conformational protective epitope in OspC. Infect. Immun. 6:1996;2234-2239.
    • (1996) Infect. Immun. , vol.6 , pp. 2234-2239
    • Gilmore R.D., Jr.1    Kappel, K.J.2    Dolan, M.C.3    Burkot, T.R.4    Johnson, B.J.5
  • 11
    • 0028331281 scopus 로고
    • Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kDa antigen
    • Probert W.S., LeFebvre R.B. Protection of C3H/HeN mice from challenge with Borrelia burgdorferi through active immunization with OspA, OspB, or OspC, but not with OspD or the 83-kDa antigen. Infect. Immun. 5:1994;1920-1926.
    • (1994) Infect. Immun. , vol.5 , pp. 1920-1926
    • Probert, W.S.1    LeFebvre, R.B.2
  • 13
    • 0033060246 scopus 로고    scopus 로고
    • Resolution of experimental and tick-borne Borrelia burgdorferi infection in mice by passive, but not active immunization using recombinant OspC
    • Zhong W., Gern L., Stehle T., Museteanu C., Kramer M., Wallich R., Simon M.M. Resolution of experimental and tick-borne Borrelia burgdorferi infection in mice by passive, but not active immunization using recombinant OspC. Eur. J. Immunol. 3:1999;946-957.
    • (1999) Eur. J. Immunol. , vol.3 , pp. 946-957
    • Zhong, W.1    Gern, L.2    Stehle, T.3    Museteanu, C.4    Kramer, M.5    Wallich, R.6    Simon, M.M.7
  • 14
    • 0031027389 scopus 로고    scopus 로고
    • Immunization with outer surface protein (Osp) A, but not OspC, provides cross-protection of mice challenged with North American isolates of Borrelia burgdorferi
    • Probert W.S., Crawford M., Cadiz R.B., LeFebvre R.B. Immunization with outer surface protein (Osp) A, but not OspC, provides cross-protection of mice challenged with North American isolates of Borrelia burgdorferi. J. Infect. Dis. 2:1997;400-405.
    • (1997) J. Infect. Dis. , vol.2 , pp. 400-405
    • Probert, W.S.1    Crawford, M.2    Cadiz, R.B.3    LeFebvre, R.B.4
  • 15
    • 0028785476 scopus 로고
    • Evidence for lateral transfer and recombination in OspC variation in Lyme disease Borrelia
    • Livey I., Gibbs C.P., Schuster R., Dorner F. Evidence for lateral transfer and recombination in OspC variation in Lyme disease Borrelia. Mol. Microbiol. 2:1995;257-269.
    • (1995) Mol. Microbiol. , vol.2 , pp. 257-269
    • Livey, I.1    Gibbs, C.P.2    Schuster, R.3    Dorner, F.4
  • 16
    • 0029000733 scopus 로고
    • Molecular analysis of genes encoding outer surface protein C (OspC) of Borrelia burgdorferi sensu lato: Relationship to ospA genotype and evidence of lateral gene exchange of ospC
    • Jauris-Heipke S., Liegl G., Preac-Mursic V., Rossler D., Schwab E., Soutschek E., Will G., Wilske B. Molecular analysis of genes encoding outer surface protein C (OspC) of Borrelia burgdorferi sensu lato: relationship to ospA genotype and evidence of lateral gene exchange of ospC. J. Clin. Microbiol. 7:1995;1860-1866.
    • (1995) J. Clin. Microbiol. , vol.7 , pp. 1860-1866
    • Jauris-Heipke, S.1    Liegl, G.2    Preac-Mursic, V.3    Rossler, D.4    Schwab, E.5    Soutschek, E.6    Will, G.7    Wilske, B.8
  • 18
    • 0029857266 scopus 로고    scopus 로고
    • Plasmid DNA and protein vaccination of mice to the outer surface protein A of Borrelia burgdorferi leads to induction of T helper cells with specificity for a major epitope and augmentation of protective IgG antibodies in vivo
    • Zhong W., Wiesmuller K.H., Kramer M.D., Wallich R., Simon M.M. Plasmid DNA and protein vaccination of mice to the outer surface protein A of Borrelia burgdorferi leads to induction of T helper cells with specificity for a major epitope and augmentation of protective IgG antibodies in vivo. Eur. J. Immunol. 11:1996;2749-2757.
    • (1996) Eur. J. Immunol. , vol.11 , pp. 2749-2757
    • Zhong, W.1    Wiesmuller, K.H.2    Kramer, M.D.3    Wallich, R.4    Simon, M.M.5
  • 19
    • 0029800616 scopus 로고    scopus 로고
    • Protective immunization with plasmid DNA containing the outer surface lipoprotein A gene of Borrelia burgdorferi is independent of an eukaryotic promoter
    • Simon M.M., Gern L., Hauser P., Zhong W., Nielsen P.J., Kramer M.D., Brenner C., Wallich R. Protective immunization with plasmid DNA containing the outer surface lipoprotein A gene of Borrelia burgdorferi is independent of an eukaryotic promoter. Eur. J. Immunol. 12:1996;2831-2840.
    • (1996) Eur. J. Immunol. , vol.12 , pp. 2831-2840
    • Simon, M.M.1    Gern, L.2    Hauser, P.3    Zhong, W.4    Nielsen, P.J.5    Kramer, M.D.6    Brenner, C.7    Wallich, R.8
  • 20
    • 0031023559 scopus 로고    scopus 로고
    • An OspA-based DNA vaccine protects mice against infection with Borrelia burgdorferi
    • Luke C.J., Carner K., Liang X., Barbour A.G. An OspA-based DNA vaccine protects mice against infection with Borrelia burgdorferi. J. Infect. Dis. 1:1997;91-97.
    • (1997) J. Infect. Dis. , vol.1 , pp. 91-97
    • Luke, C.J.1    Carner, K.2    Liang, X.3    Barbour, A.G.4
  • 22
    • 0033797173 scopus 로고    scopus 로고
    • Genetic vaccination against malaria infection by intradermal and epidermal injections of a plasmid containing the gene encoding the Plasmodium berghei circumsporozoite protein
    • Weiss R., Leitner W.W., Scheiblhofer S., Chen D., Bernhaupt A., Mostbock S., Thalhamer J., Lyon J.A. Genetic vaccination against malaria infection by intradermal and epidermal injections of a plasmid containing the gene encoding the Plasmodium berghei circumsporozoite protein. Infect. Immun. 10:2000;5914-5919.
    • (2000) Infect. Immun. , vol.10 , pp. 5914-5919
    • Weiss, R.1    Leitner, W.W.2    Scheiblhofer, S.3    Chen, D.4    Bernhaupt, A.5    Mostbock, S.6    Thalhamer, J.7    Lyon, J.A.8
  • 23
    • 0031093543 scopus 로고    scopus 로고
    • Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization
    • Feltquate D.M., Heaney S., Webster R.G., Robinson H.L. Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization. J. Immunol. 5:1997;2278-2284.
    • (1997) J. Immunol. , vol.5 , pp. 2278-2284
    • Feltquate, D.M.1    Heaney, S.2    Webster, R.G.3    Robinson, H.L.4
  • 24
    • 0035084743 scopus 로고    scopus 로고
    • DNA vaccines expressing a fusion product of outer surface proteins A and C from Borrelia burgdorferi induce protective antibodies suitable for prophylaxis but not for resolution of Lyme disease
    • Wallich R., Siebers A., Jahraus O., Brenner C., Stehle T., Simon M.M. DNA vaccines expressing a fusion product of outer surface proteins A and C from Borrelia burgdorferi induce protective antibodies suitable for prophylaxis but not for resolution of Lyme disease. Infect. Immun. 4:2001;2130-2136.
    • (2001) Infect. Immun. , vol.4 , pp. 2130-2136
    • Wallich, R.1    Siebers, A.2    Jahraus, O.3    Brenner, C.4    Stehle, T.5    Simon, M.M.6
  • 27
    • 0030791541 scopus 로고    scopus 로고
    • Biological features of genetic immunization
    • Barry M.A., Johnston S.A. Biological features of genetic immunization. Vaccine. 8:1997;788-791.
    • (1997) Vaccine , vol.8 , pp. 788-791
    • Barry, M.A.1    Johnston, S.A.2
  • 28
    • 0037135660 scopus 로고    scopus 로고
    • Gene gun bombardment with gold particles displays a particular Th2-promoting signal that overrules the Th1-inducing effect of immunostimulatory CpG motifs in DNA vaccines
    • Weiss R., Scheiblhofer S., Freund J., Ferreira F., Livey I., Thalhamer J. Gene gun bombardment with gold particles displays a particular Th2-promoting signal that overrules the Th1-inducing effect of immunostimulatory CpG motifs in DNA vaccines. Vaccine. 20:2002;3148-3154.
    • (2002) Vaccine , vol.20 , pp. 3148-3154
    • Weiss, R.1    Scheiblhofer, S.2    Freund, J.3    Ferreira, F.4    Livey, I.5    Thalhamer, J.6
  • 29
    • 0031569601 scopus 로고    scopus 로고
    • Contribution of CpG motifs to the immunogenicity of DNA vaccines
    • Klinman D.M., Yamshchikov G., Ishigatsubo Y. Contribution of CpG motifs to the immunogenicity of DNA vaccines. J. Immunol. 8:1997;3635-3639.
    • (1997) J. Immunol. , vol.8 , pp. 3635-3639
    • Klinman, D.M.1    Yamshchikov, G.2    Ishigatsubo, Y.3
  • 30
    • 0031986558 scopus 로고    scopus 로고
    • Mitogenic synthetic polynucleotides suppress the antibody response to a bacterial polysaccharide
    • Threadgill D.S., McCormick L.L., McCool T.L., Greenspan N.S., Schreiber J.R. Mitogenic synthetic polynucleotides suppress the antibody response to a bacterial polysaccharide. Vaccine. 1:1998;76-82.
    • (1998) Vaccine , vol.1 , pp. 76-82
    • Threadgill, D.S.1    McCormick, L.L.2    McCool, T.L.3    Greenspan, N.S.4    Schreiber, J.R.5
  • 32
    • 0035045007 scopus 로고    scopus 로고
    • The influence of CpG motifs on a protein or DNA-based Th2-type immune response against major pollen allergens Bet v 1a, Phl p 2 and Escherichia coli-derived β-galactosidase
    • Hochreiter R., Hartl A., Freund J., Valenta R., Ferreira F., Thalhamer J. The influence of CpG motifs on a protein or DNA-based Th2-type immune response against major pollen allergens Bet v 1a, Phl p 2 and Escherichia coli-derived β-galactosidase. Int. Arch. Allergy Immunol. 1-3:2001;406-410.
    • (2001) Int. Arch. Allergy Immunol. , vol.1-3 , pp. 406-410
    • Hochreiter, R.1    Hartl, A.2    Freund, J.3    Valenta, R.4    Ferreira, F.5    Thalhamer, J.6
  • 33
    • 0345211498 scopus 로고    scopus 로고
    • DNA immunization is associated with increased activity of type I iodothyronine 5′-deiodinase in mouse liver
    • Brtko J., Mostbock S., Scheiblhofer S., Hartl A., Thalhamer J. DNA immunization is associated with increased activity of type I iodothyronine 5′-deiodinase in mouse liver. Mol. Cell. Endocrinol. 1-2:1999;85-89.
    • (1999) Mol. Cell. Endocrinol. , vol.1-2 , pp. 85-89
    • Brtko, J.1    Mostbock, S.2    Scheiblhofer, S.3    Hartl, A.4    Thalhamer, J.5


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