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Volumn 183, Issue 1, 1996, Pages 261-269

Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: Exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease

Author keywords

[No Author keywords available]

Indexed keywords

OUTER MEMBRANE PROTEIN; PROTEIN A; PROTEIN C;

EID: 0030048119     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.1.261     Document Type: Article
Times cited : (178)

References (39)
  • 1
    • 0002893627 scopus 로고    scopus 로고
    • Lyme disease
    • R.R. Rich, editor. Mosby-Year Book, St. Louis, MO
    • Bockenstedt, L.K., and S.E. Malawista. 1996. Lyme disease. In Clinical Immunology. R.R. Rich, editor. Mosby-Year Book, St. Louis, MO 1234-1249.
    • (1996) Clinical Immunology , pp. 1234-1249
    • Bockenstedt, L.K.1    Malawista, S.E.2
  • 3
    • 0022999139 scopus 로고
    • Antigens of Borrelia burgdorferi recognized during Lyme disease: Appearance of a new immunoglobulin M response and expansion of the immunoglobulin G response late in the illness
    • Craft, J.E., D.K. Fisher, G.T. Shimamoto, and A.C. Steere. 1986. Antigens of Borrelia burgdorferi recognized during Lyme disease: appearance of a new immunoglobulin M response and expansion of the immunoglobulin G response late in the illness. J. Clin. Invest. 78:934-939.
    • (1986) J. Clin. Invest. , vol.78 , pp. 934-939
    • Craft, J.E.1    Fisher, D.K.2    Shimamoto, G.T.3    Steere, A.C.4
  • 5
    • 0025014625 scopus 로고
    • Isolation of Borrelia burgdorferi from the myocardium of a patient with longstanding cardiomyopathy
    • Stanek, G., J. Klein, R. Bittner, and D. Glogar. 1990. Isolation of Borrelia burgdorferi from the myocardium of a patient with longstanding cardiomyopathy. N. Engl. J. Med. 322: 249-252.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 249-252
    • Stanek, G.1    Klein, J.2    Bittner, R.3    Glogar, D.4
  • 6
    • 0023694063 scopus 로고
    • Lyme myositis: Muscle invasion by Borrelia burgdorferi
    • Atlas, E., S.N. Novak, P.H. Duray, and A.C. Steere. 1988. Lyme myositis: muscle invasion by Borrelia burgdorferi. Ann. Intern. Med. 109:245-246.
    • (1988) Ann. Intern. Med. , vol.109 , pp. 245-246
    • Atlas, E.1    Novak, S.N.2    Duray, P.H.3    Steere, A.C.4
  • 7
    • 0013614630 scopus 로고
    • Lyme borreliosis in the laboratory mouse
    • S.E. Schutzer, editor. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Barthold, S.W., M. de Souza, E. Fikrig, and D.H. Persing. 1992. Lyme borreliosis in the laboratory mouse. In Lyme Disease: Molecular and Immunologic Approaches. S.E. Schutzer, editor. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 223-242.
    • (1992) Lyme Disease: Molecular and Immunologic Approaches , pp. 223-242
    • Barthold, S.W.1    De Souza, M.2    Fikrig, E.3    Persing, D.H.4
  • 8
    • 0022529650 scopus 로고
    • Organization of genes encoding two outer membrane proteins of the Lyme disease agent Borrelia burgdorferi within a single transcriptional unit
    • Howe, T.R., F.W. LaQuier, and A.G. Barbour. 1986. Organization of genes encoding two outer membrane proteins of the Lyme disease agent Borrelia burgdorferi within a single transcriptional unit. Infect. Immun. 54:207-212.
    • (1986) Infect. Immun. , vol.54 , pp. 207-212
    • Howe, T.R.1    LaQuier, F.W.2    Barbour, A.G.3
  • 9
    • 0025202254 scopus 로고
    • Protection of mice against the Lyme disease agent by immunizing with recombinant OspA
    • Fikrig, E., S.W. Barthold, F.S. Kantor, and R.A. Flavell. 1990. Protection of mice against the Lyme disease agent by immunizing with recombinant OspA. Science (Wash. DC). 250, 553-556.
    • (1990) Science (Wash. DC) , vol.250 , pp. 553-556
    • Fikrig, E.1    Barthold, S.W.2    Kantor, F.S.3    Flavell, R.A.4
  • 10
    • 0025333897 scopus 로고
    • Monoclonal antibodies specific for the outer surface protein A (Osp A) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice
    • Schaible, U.E., M.D. Kramer, K. Eichmann, M. Modolell, C. Museteanu, and M.M. Simon. 1990. Monoclonal antibodies specific for the outer surface protein A (Osp A) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice. Proc. Natl. Acad. Sci. USA. 87: 3768-3772.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 3768-3772
    • Schaible, U.E.1    Kramer, M.D.2    Eichmann, K.3    Modolell, M.4    Museteanu, C.5    Simon, M.M.6
  • 11
    • 0025949089 scopus 로고
    • Recombinant outer surface protein A from Borrelia burgdorferi induces antibodies protective against spirochetal infection in mice
    • Simon, M.M., U.E. Schaible, M.D. Kramer, C. Eckerskorn, C. Museteanu, H.K. Muller-Hermelink, and R. Wallich. 1991. Recombinant outer surface protein A from Borrelia burgdorferi induces antibodies protective against spirochetal infection in mice. J. Infect. Dis. 164:123-132.
    • (1991) J. Infect. Dis. , vol.164 , pp. 123-132
    • Simon, M.M.1    Schaible, U.E.2    Kramer, M.D.3    Eckerskorn, C.4    Museteanu, C.5    Muller-Hermelink, H.K.6    Wallich, R.7
  • 12
    • 0028218706 scopus 로고
    • Immunization of mice by recombinant Osp A preparations and protection against Borrelia burgdorferi infection induced by Ixodes ricinus ticks
    • Gern, L., O. Rais, C. Capiau, P. Hauser, Y. Lobet, E. Simoen, P. Voet, and J. Petre. 1994. Immunization of mice by recombinant Osp A preparations and protection against Borrelia burgdorferi infection induced by Ixodes ricinus ticks. Immunol. Lett. 39:249-258.
    • (1994) Immunol. Lett. , vol.39 , pp. 249-258
    • Gern, L.1    Rais, O.2    Capiau, C.3    Hauser, P.4    Lobet, Y.5    Simoen, E.6    Voet, P.7    Petre, J.8
  • 13
    • 0027207678 scopus 로고
    • Osp A vaccination of mice with established Borrelia burgdorferi infection alters disease but not infection
    • Fikrig, E., S.W. Barthold, and R.A. Flavell. 1993. Osp A vaccination of mice with established Borrelia burgdorferi infection alters disease but not infection. Infect. Immun. 61:2553-2557.
    • (1993) Infect. Immun. , vol.61 , pp. 2553-2557
    • Fikrig, E.1    Barthold, S.W.2    Flavell, R.A.3
  • 15
    • 0027367841 scopus 로고
    • Antigenic stability of Borrelia burgdorferi during chronic infections of immunocompetent mice
    • Barthold, S.W. 1993. Antigenic stability of Borrelia burgdorferi during chronic infections of immunocompetent mice. Infect. Immun. 61:4955-4961.
    • (1993) Infect. Immun. , vol.61 , pp. 4955-4961
    • Barthold, S.W.1
  • 16
    • 0029036568 scopus 로고
    • Circumvention of outer surface protein A immunity by host-adapted Borrelia burgdorferi
    • Barthold, S.W., E. Fikrig, L.K. Bockenstedt, and D.H. Persing. 1995. Circumvention of outer surface protein A immunity by host-adapted Borrelia burgdorferi. Infect. Immun. 63:2255-2261.
    • (1995) Infect. Immun. , vol.63 , pp. 2255-2261
    • Barthold, S.W.1    Fikrig, E.2    Bockenstedt, L.K.3    Persing, D.H.4
  • 17
    • 0026529325 scopus 로고
    • Molecular analysis and expression of a Borrelia burgdorferi gene encoding a 22 kDa protein (pC) in Escherichia coli
    • Fuchs, R., S. Jauris, F. Lottspeich, V. Preac-Mursic, B. Wilske, and E. Soutschek. 1992. Molecular analysis and expression of a Borrelia burgdorferi gene encoding a 22 kDa protein (pC) in Escherichia coli. Mol. Microbiol. 6:503-509.
    • (1992) Mol. Microbiol. , vol.6 , pp. 503-509
    • Fuchs, R.1    Jauris, S.2    Lottspeich, F.3    Preac-Mursic, V.4    Wilske, B.5    Soutschek, E.6
  • 18
    • 0027483788 scopus 로고
    • Molecular characterization and expression of p23 (Osp C) from a North American strain of Borrelia burgdorferi
    • Padula, S.J., A. Sampieri, F. Dias, A. Szczepanski, and R.W. Ryan. 1993. Molecular characterization and expression of p23 (Osp C) from a North American strain of Borrelia burgdorferi. Infect. Immun. 61:5097-5015.
    • (1993) Infect. Immun. , vol.61 , pp. 5097-15015
    • Padula, S.J.1    Sampieri, A.2    Dias, F.3    Szczepanski, A.4    Ryan, R.W.5
  • 19
    • 0028026934 scopus 로고
    • Humoral immune response to outer surface protein C of Borrelia burgdorferi in Lyme disease: Role of the immunoglobulin M response in the serodiagnosis of early infection
    • Fung, B.P., G.L. McHugh, J.M. Leong, and A.C. Steere. 1994. Humoral immune response to outer surface protein C of Borrelia burgdorferi in Lyme disease: role of the immunoglobulin M response in the serodiagnosis of early infection. Infect Immun. 62:3213-3221.
    • (1994) Infect Immun. , vol.62 , pp. 3213-3221
    • Fung, B.P.1    McHugh, G.L.2    Leong, J.M.3    Steere, A.C.4
  • 20
    • 0027963449 scopus 로고
    • Expression and gene sequence of outer surface protein C of Borrelia burgdorferi reisolated from chronically infected mice
    • Stevenson, B., L.K. Bockenstedt, and S.W. Barthold. 1994. Expression and gene sequence of outer surface protein C of Borrelia burgdorferi reisolated from chronically infected mice. Infect. Immun. 62:3568-3571.
    • (1994) Infect. Immun. , vol.62 , pp. 3568-3571
    • Stevenson, B.1    Bockenstedt, L.K.2    Barthold, S.W.3
  • 21
    • 0027288183 scopus 로고
    • Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to Osp A and Osp B
    • Kalish, R.A., J.M. Leong, and A.C. Steere. 1993. Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to Osp A and Osp B. Infect. Immun. 61:2774-2779.
    • (1993) Infect. Immun. , vol.61 , pp. 2774-2779
    • Kalish, R.A.1    Leong, J.M.2    Steere, A.C.3
  • 23
    • 0028200919 scopus 로고
    • Tick transmission of Borrelia burgdorferi to inbred strains of mice induces an antibody response to p39 but not to outer surface protein A
    • Golde, W.T., K.J. Kappel, G. Dequesne, C. Feron, D. Plarinchamp, C. Capiau, and Y. Lobet. 1994. Tick transmission of Borrelia burgdorferi to inbred strains of mice induces an antibody response to p39 but not to outer surface protein A. Infect. Immun. 62:2625-2627.
    • (1994) Infect. Immun. , vol.62 , pp. 2625-2627
    • Golde, W.T.1    Kappel, K.J.2    Dequesne, G.3    Feron, C.4    Plarinchamp, D.5    Capiau, C.6    Lobet, Y.7
  • 25
    • 0027934212 scopus 로고
    • Quantitation of the Borrelia burgdorferi outer surface protein A in Ixodes scapularis: Fluctuations during the tick life cycle doubling times, and loss while feeding
    • Burkot, T.R., J. Piesman, and R.A. Wirtz. 1994. Quantitation of the Borrelia burgdorferi outer surface protein A in Ixodes scapularis: fluctuations during the tick life cycle doubling times, and loss while feeding. J. Infect. Dis. 170:883-889.
    • (1994) J. Infect. Dis. , vol.170 , pp. 883-889
    • Burkot, T.R.1    Piesman, J.2    Wirtz, R.A.3
  • 26
    • 0028842880 scopus 로고
    • The growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding
    • 25b. de Silva, A.M., and E. Fikrig. 1995. The growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding. Am. J. Trap. Med. Hyg. 53:397-404.
    • (1995) Am. J. Trap. Med. Hyg. , vol.53 , pp. 397-404
    • De Silva, A.M.1    Fikrig, E.2
  • 27
    • 0027154659 scopus 로고
    • The fate of Borrelia burgdorferi, the agent for Lyme disease, in mouse macrophages: Destruction, survival, recovery
    • Montgomery, R.R., M.H. Nathanson, and S.E. Malawista. 1993. The fate of Borrelia burgdorferi, the agent for Lyme disease, in mouse macrophages: destruction, survival, recovery. J. Immunol. 150:909-915.
    • (1993) J. Immunol. , vol.150 , pp. 909-915
    • Montgomery, R.R.1    Nathanson, M.H.2    Malawista, S.E.3
  • 29
    • 0025509132 scopus 로고
    • Outer surface protein A (Osp A) from the Lyme disease spirochete, Borrelia burgdorferi: High level expression and purification of a soluble recombinant form of OspA
    • Dunn, J.J., B.N. Lade, and A.G. Barbour. 1990. Outer surface protein A (Osp A) from the Lyme disease spirochete, Borrelia burgdorferi: high level expression and purification of a soluble recombinant form of OspA. Protein Expression and Purification. 1:159-168.
    • (1990) Protein Expression and Purification. , vol.1 , pp. 159-168
    • Dunn, J.J.1    Lade, B.N.2    Barbour, A.G.3
  • 30
    • 0026596492 scopus 로고
    • Interactions between extracellular Borrelia burgdorferi proteins and non-Borrelia-directed immunoglobulin M antibodies
    • Dorward, D.W., E.D. Huguenel, G. Davis, and C.F. Garon. 1992. Interactions between extracellular Borrelia burgdorferi proteins and non-Borrelia-directed immunoglobulin M antibodies. Infect. Immun. 60:838-844.
    • (1992) Infect. Immun. , vol.60 , pp. 838-844
    • Dorward, D.W.1    Huguenel, E.D.2    Davis, G.3    Garon, C.F.4
  • 31
    • 0026669299 scopus 로고
    • Carditis in Lyme disease susceptible and resistant strains of laboratory mice infected with Borrelia burgdorferi
    • Armstrong, A.L., S.W. Barthold, D.H. Persing, and D.S Beck. 1992. Carditis in Lyme disease susceptible and resistant strains of laboratory mice infected with Borrelia burgdorferi. Am. J. Trop. Med. Hyg. 47:249-258.
    • (1992) Am. J. Trop. Med. Hyg. , vol.47 , pp. 249-258
    • Armstrong, A.L.1    Barthold, S.W.2    Persing, D.H.3    Beck, D.S.4
  • 32
    • 0028926240 scopus 로고
    • Induction of an outer surface protein on Borrelia burgdorferi during tick feeding
    • Schwan, T.G., J. Piesman, W.T. Golde, M.C. Dolan, and P.A. Rosa. 1995. Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc. Natl. Acad. Sci. USA. 92: 2909-2913.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2909-2913
    • Schwan, T.G.1    Piesman, J.2    Golde, W.T.3    Dolan, M.C.4    Rosa, P.A.5
  • 34
    • 0023124841 scopus 로고
    • Programmed gene rearrangements altering gene expression
    • Borst, P., and D.R. Greaves. 1987. Programmed gene rearrangements altering gene expression. Science (Wash. DC). 235: 658-667.
    • (1987) Science (Wash. DC) , vol.235 , pp. 658-667
    • Borst, P.1    Greaves, D.R.2
  • 35
    • 0026666212 scopus 로고
    • Monoclonal antibodies to a 16-kDa antigen of Serpulina (Treponema) hyodysenteriae
    • Thomas, W., and R. Sellwood. 1992. Monoclonal antibodies to a 16-kDa antigen of Serpulina (Treponema) hyodysenteriae. J. Med. Microbiol. 37:214-220.
    • (1992) J. Med. Microbiol. , vol.37 , pp. 214-220
    • Thomas, W.1    Sellwood, R.2
  • 36
    • 0027295182 scopus 로고
    • Regulation of expression of major outer surface proteins in Borrelia burgdorferi
    • Margolis, N., and P.A. Rosa. 1993. Regulation of expression of major outer surface proteins in Borrelia burgdorferi. Infect. Immun. 61:2207-2210
    • (1993) Infect. Immun. , vol.61 , pp. 2207-2210
    • Margolis, N.1    Rosa, P.A.2
  • 37
    • 0026658940 scopus 로고
    • Nucleotide sequence of the ospAB operon of a Borrelia burgdorferi strain expressing Osp A but not Osp B
    • Eiffert, H., A. Ohlenbusch, W. Fehling, H. Lotter, and R. Thomssen. 1992. Nucleotide sequence of the ospAB operon of a Borrelia burgdorferi strain expressing Osp A but not Osp B. Infect. Immun. 60:1864-1868.
    • (1992) Infect. Immun. , vol.60 , pp. 1864-1868
    • Eiffert, H.1    Ohlenbusch, A.2    Fehling, W.3    Lotter, H.4    Thomssen, R.5
  • 38
    • 0023753146 scopus 로고
    • Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation
    • Schwan, T.G., W. Burgdorfer, and C.F. Garon. 1988. Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation. Infect. Immun. 56:1831-1836.
    • (1988) Infect. Immun. , vol.56 , pp. 1831-1836
    • Schwan, T.G.1    Burgdorfer, W.2    Garon, C.F.3
  • 39
    • 0020316296 scopus 로고
    • The protective role of acquired host antigens during schistosome maturation
    • McLaren, D.J., and R.J. Terry. 1982. The protective role of acquired host antigens during schistosome maturation. Parasite Immunol. 4:129-148.
    • (1982) Parasite Immunol. , vol.4 , pp. 129-148
    • McLaren, D.J.1    Terry, R.J.2


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