Protective immunization with plasmid DNA containing the outer surface lipoprotein A gene of Borrelia burgdorferi is independent of an eukaryotic promoter

European Journal of Immunology

Volumn 26, Issue 12, 1996, Pages 2831-2840

  Simon, Markus M ^a   Gern, Lise ^b   Hauser, Pierre ^c   Zhong, Weimin ^a   Nielsen, Peter J ^a   Kramer, Michael D ^d   Brenner, Christiane ^d   Wallich, Reinhard ^d  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^b UNIVERSITY OF NEUCHÂTEL   (Switzerland)

^c GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Borrelia burgdorferi; Gene regulation; Lyme disease; Spirochetes; Vaccination

Indexed keywords

LIPOPROTEIN A; PLASMID DNA;

ANTIBODY TITER; ARTICLE; BACTERIAL GENE; BORRELIA BURGDORFERI; CONTROLLED STUDY; FEMALE; GENE; IMMUNIZATION; LYME DISEASE; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; SPIROCHETE; STRUCTURAL GENE;

EID: 0029800616     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830261206     Document Type: Article

References (55)

1. Steere, A. C., N. Engl. J. Med. 1989. 321: 586.
2. Garcia Monco, J. C. and Benach, J. L., Ann. Neural. 1995. 37: 691.
3. Schaible, U. E., Kramer, M. D., Eichmann, K., Modolell, M., Museteanu, C. and Simon, M. M., Proc. Natl. Acad. Sci. USA 1990. 87: 3768.
4. Fikrig, E., Barthold, S. W., Kantor, F. S. and Flavell, R. A., Science 1990. 250: 553.
5. Simon, M. M., Schaible, U. E., Kramer, M. D., Eckerskorn, C., Museteanu, C., Müller-Hermelink, H. K. and Wallich, R., J. Infect. Dis. 1991. 164: 123.
6. Schaible, U. E., Wallich, R., Kramer, M. D., Nerz, G., Stehle, T., Museteanu, C. and Simon, M. M., Int. Immunol. 1994. 6: 671.
7. Wallich, R., Helmes, C., Schaible, U. E., Lobet, Y., Moter, S. E., Kramer, M. D. and Simon, M. M., Infect. Immun. 1992. 60: 4856.
8. Wilske, B., Luft, B., Schubach, W. H., Zumstein, G., Jauris, S., Preac-Mursic, V. and Kramer, M. D., Med. Microbiol. Immunol. 1992. 181: 191.
9. Schaible, U. E., Wallich, R., Kramer, M. D., Gern, L., Andersen, J. F., Museteanu, C. and Simon, M. M., Vaccine 1993. 11: 1049.
10. Fikrig, E., Telford, S. R. III, Wallich, R., Chen, M., Lobet, Y., Matuschka. F. R., Kimsey, R. B., Kantor, F. S., Barthold, S. W., Spielman, A. and Flavell, R. A., J. Exp. Med. 1995. 181: 215.
11. Golde, W. T., Burkot, T. R., Piesman, J., Dolan, M. C., Capiau, C., Hauser, P., Dequesne, G. and Lobet, Y., Vaccine 1995. 13: 435.
12. Van Hoecke, C., De Grave, D., Hauser, P. and Lebacq, E., in Cevenini, R., Sambri, V. and La Placa, M. (Eds.), Advances in Lyme borreliosis research. Proceedings of the VI International Conference on Lyme borreliosis, Societa Editrice Esculapio, Bologna, Italy 1994. p. 123.
13. Keller, D., Koster, FT., Marks, D. H., Hosbach, P., Erdile, L. F. and Mays, J. P., JAMA 1994. 271: 1764.
14. Wolff, J. A., Malone, R. W., Williams, P., Chong, W., Acsadi, G., Jani, A. and Felgner, P. L., Science 1990. 247: 1465.
15. Wolff, J. A., Ludtke, J. J., Acsadi, G., Williams, P. and Jani, A., Adv. Exp. Med. Biol. 1992. 383: 73.
16. Ulmer, J. B., Donnelly, J. J., Parker, S. E., Rhodes, G. H., Felgner, P. L., Dwarki. V. J., Gromkowski, S. H., Deck, R. R., DeWitt, C. M., Friedman, A., Hawe, L. A., Leander, K. R., Martinez, D., Perry, H. C., Shiver, J. W., Montgomery, D. L. and Liu, M. A., Science 1993. 259: 1745.
17. Raz, E., Carson, D. A., Parker, S. E., Parr, T. B., Abai, A. M., Aichinger, G., Gromkowski, S. H., Singh, M., Lew, D., Yankauckas, M. A., Baird, S. M. and Rhodes, G. H., Proc. Natl. Acad. Sci. USA 1995. 91: 9519.
18. Danko, I. and Wolff, J. A., Vaccine 1994. 12: 1499.
19. Whalen, R. G., Leclere, C., Deriaud, E., Schirmbeck, R., Reimann, J. and Davis, H. L., Ann. NY Acad. Sci. 1995. 772: 64.
20. Wang, B., Ugen, K. E., Srikantan, V., Agadjanyan, M. G., Dang, K., Refaeli, Y., Sato, A. I., Boyer, J., Williams, W. V. and Weiner, D. B., Proc. Natl. Acad. Sci. USA 1993. 90: 4156.
21. Yiang, Z. Q., Spitalnik, S., Tran, M., Wunner, W. H., Cheng, J. and Ertl, H. C., Virology 1994. 199: 132.
22. Barry, M. A., Lai, W. C. and Johnston, S. A., Nature 1995. 377: 632.
23. Sedegah, M., Hedstrom, R., Hobart, P. and Hoffman, S. L., Proc. Natl. Acad. Sci. USA 1994. 91: 9866.
24. Gern, L., Rais, O., Capiau, C., Hauser, P., Lobet, Y., Simoen, E., Voet, P. and Pêtre, J., Immunol. Lett. 1994. 39: 249.
25. Wallich, R., Schaible, U. E., Simon, M. M., Heiberger, A. and Kramer, M. D., Nucleic Acids Res. 1989. 17: 8864.
26. Mizushima, S. and Nagata, S., Nucleic Acids Res. 1990. 18: 5322.
27. Rittner, K., Stöppler, H., Pawlita, M. and Sczakiel, G., Methods Mol. Cell. Biol. 1991. 2: 176.
28. Wallich, R., Simon, M. M., Hofmann, H., Moter, S. E., Schaible, U. E. and Kramer, M. D., Infect. Immun. 1993. 61: 4158.
29. Kim, K. J., Kanellopulos-Langevin, C., Merwin, R. M., Sachs, D. H. and Asofsky, R., J. Immunol. 1979. 122: 549.
30. Wenger, R. H., Rochelle, J. M., Seldin, M. F., Köhler, G. and Nielsen, P. J., J. Biol. Chem. 1993. 268: 23345.
31. Sambrook, J., Fritsch, E. F. and Maniatis, T., Molecular cloning: A laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, 1989.
32. Schaible, U. E., Kramer, M. D., Wallich, R., Tran, T. and Simon, M. M., Eur. J. Immmol. 1991. 21: 2397.
33. Kramer, M. D., Schaible, U. E., Wallich, R., Moter, S., Petzoldt, D. and Simon, M. M., Immunobiology 1990. 181: 357.
34. Wallich, R., Brenner, C., Kramer, M. D. and Simon, M. M., Infect. Immun. 1995. 63: 3327.
35. Schaible, U. E., Gay, S., Museteanu, C., Kramer, M. D., Zimmer, G., Eichmann, K., Museteanu, U. and Simoon, M. M., Am. J. Pathol. 1990. 137: 811.
36. Simon, M. M., Nerz, G., Kramer, M. D., Hurtenbach, U., Schaible, U. E. and Wallich, R., Immmol Lett. 1995. 45: 137.
37. Knigge, H., Simon, M. M., Meuer, S. C., Kramer, M. D. and Wallich, R., Eur. J. Immunol. 1996. 26: 2292.
38. Johnson, B. J. B., Sviat, S. L., Happ, C. M., Dunn, J. J., Frantz, J. C., Mayer, L. W. and Piesman, J., Vaccine 1995. 13: 1086.
39. Frantz, J., Golde, W., Piesman, J., Dolan, M., Kramer, M. D., Simon, M. M. and Hauser, P., in Seventy-sixth conference of research workers in animal diseases, Fort Collins, 1995.
40. Manthorpe, M., Cornefert-Jensen, F., Hartikka, J., Felgner, J., Rundell, A., Margalith, M. and Dwarki, V., Hum. Gene Ther, 1993. 4: 419.
41. Barbour, A. G. and Garon, C. F., Science 1987. 237: 409.
42. Corden, J., Wasylyk, B., Buchwalder, A., Sassone-Corsi, P., Kedinger, C. and Chambon, P., Science 1980. 209: 1406.
43. Benoist, C., O'Hare, K., Breathnach, R. and Chambon, P., Nucleic Adds Res. 1980. 8: 127.
44. Kihara, F. and Ariga, H., Biochim. Biophys. Acta 1991. 1089: 227.
45. Ma, Y., Sturrock, A. and Weis, J. J., Infect. Immun. 1991. 59: 671.
46. Georgilis, K., Peacocke, M. and Klempner, M. S., J. Infect. Dis. 1992. 166: 440.
47. Simon, M. M., Wallich, R. and Kramer, M. D., J. Spirochetal Tick-Borne Dis. 1996. 3: 45.
48. Braun, V. and Wu, H. C., in Ghuysen, J.-M. and Chambon, P. (Eds.), Bacterial Cell Wall, Eisevier, Amsterdam. 1994, p. 319.
49. Yssel, H., Shanafelt, M.-C., Soderberg, C., Schneider, P. V., Anzola, J. and Peltz, G., J. Exp. Med. 1991. 174: 593.
50. Keane-Myers, A. and Nickell, S. P., J. Immunol. 1995. 155: 2020.
51. Matyniak, J. E. and Reiner, S. L., J. Exp. Med. 1995. 181: 1251.
52. Zhong, W., Weismüller, K.-H., Kramer, M. D., Wallich, R. and Simon, M. M., Eur. J. Immunol. 1996. 26: in press.
53. Fikrig, E.,Tao, H., Chen, M. C., Barthold, S. W. and Flavell, R. A., J. Clin. Invest. 1995. 96: 1706.
54. Kalish, R. A., Leong, J. M. and Steere, A. C., Infect. Immun. 1993. 61: 2774.
55. Lengl-Janssen, B., Strauss, A. F., Steere, A. C. and Kamradt, T., J. Exp. Med. 1994. 180: 2069.