메뉴 건너뛰기




Volumn 103, Issue 1 I, 1999, Pages 107-113

Immune responses after immunization with plasmid DNA encoding Bet v 1, the major allergen of birch pollen

Author keywords

Balbic; Bet v 1; Birch pollen allergen; DNA immunization; Immunotherapy

Indexed keywords

PLASMID DNA;

EID: 0032944136     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(99)70533-6     Document Type: Article
Times cited : (84)

References (35)
  • 2
    • 0026579897 scopus 로고
    • Genetic immunization is a simple method for eliciting an immune response
    • Tang DC, DeVit M, Johnston SA. Genetic immunization is a simple method for eliciting an immune response. Nature 1992;356:152-4.
    • (1992) Nature , vol.356 , pp. 152-154
    • Tang, D.C.1    DeVit, M.2    Johnston, S.A.3
  • 3
    • 0028060149 scopus 로고
    • Intradermal gene immunization: The possible role of DNA uptake in the induction of cellular immunity to viruses
    • Raz E, Carson DA, Parker SE, Parr TB, Abai AM, Aichinger G, et al. Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proc Natl Acad Sci USA 1994;91:9519-23.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9519-9523
    • Raz, E.1    Carson, D.A.2    Parker, S.E.3    Parr, T.B.4    Abai, A.M.5    Aichinger, G.6
  • 4
    • 0027713222 scopus 로고
    • Plasmid DNA is superior to viral vectors for direct gene transfer into adult mouse skeletal muscle
    • Davis HL, Demeneix BA, Quantin B, Coulombe J, Whalen RG. Plasmid DNA is superior to viral vectors for direct gene transfer into adult mouse skeletal muscle. Hum Gene Ther 1993;4:733-40.
    • (1993) Hum Gene Ther , vol.4 , pp. 733-740
    • Davis, H.L.1    Demeneix, B.A.2    Quantin, B.3    Coulombe, J.4    Whalen, R.G.5
  • 5
  • 6
    • 0029789751 scopus 로고    scopus 로고
    • Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: Antigen presentation by non-muscle cells
    • Ulmer JB, Deck RR, Dewitt CM, Donnhly JI, Liu MA. Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: antigen presentation by non-muscle cells. Immunology 1996;89:59-67.
    • (1996) Immunology , vol.89 , pp. 59-67
    • Ulmer, J.B.1    Deck, R.R.2    Dewitt, C.M.3    Donnhly, J.I.4    Liu, M.A.5
  • 7
    • 0029737350 scopus 로고    scopus 로고
    • Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells
    • Doe B, Selby M, Barnett S, Baenziger J, Walker CM. Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells. Proc Natl Acad Sci USA 1996;93:8578-83.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8578-8583
    • Doe, B.1    Selby, M.2    Barnett, S.3    Baenziger, J.4    Walker, C.M.5
  • 8
    • 0029882212 scopus 로고    scopus 로고
    • In vivo cross-priming of MHC class I-restricted antigens requires the TAP transporter
    • Huang AY, Bruce AT, Pardoll DM, Levitsky HI. In vivo cross-priming of MHC class I-restricted antigens requires the TAP transporter. Immunity 1996;4:349-55.
    • (1996) Immunity , vol.4 , pp. 349-355
    • Huang, A.Y.1    Bruce, A.T.2    Pardoll, D.M.3    Levitsky, H.I.4
  • 9
    • 8944253295 scopus 로고    scopus 로고
    • Immunostimulatory DNA sequences necessary for effective intradermal gene immunization
    • Sato Y, Roman M, Tighe H, Lee D, Corr M, Nguyen MD, et al. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science 1996;273:352-4.
    • (1996) Science , vol.273 , pp. 352-354
    • Sato, Y.1    Roman, M.2    Tighe, H.3    Lee, D.4    Corr, M.5    Nguyen, M.D.6
  • 11
    • 0029984358 scopus 로고    scopus 로고
    • CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma
    • Klinman DM, Yi AK, Beaucage SL, Conover J, Krieg AM. CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma. Proc Natl Acad Sci U S A 1996;93:2879-83.
    • (1996) Proc Natl Acad Sci U S a , vol.93 , pp. 2879-2883
    • Klinman, D.M.1    Yi, A.K.2    Beaucage, S.L.3    Conover, J.4    Krieg, A.M.5
  • 12
    • 0031093543 scopus 로고    scopus 로고
    • Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization
    • Feltquate DM, Heaney S, Webster RG, Robinson HL. Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization. J Immunol 1997;158:2278-84.
    • (1997) J Immunol , vol.158 , pp. 2278-2284
    • Feltquate, D.M.1    Heaney, S.2    Webster, R.G.3    Robinson, H.L.4
  • 13
    • 0030791541 scopus 로고    scopus 로고
    • Biological features of genetic immunization
    • Barry MA, Johnston SA. Biological features of genetic immunization. Vaccine 1997;15:788-91.
    • (1997) Vaccine , vol.15 , pp. 788-791
    • Barry, M.A.1    Johnston, S.A.2
  • 14
    • 0022003271 scopus 로고
    • Development of IgE and IgG antibodies to food and inhalant allergens in children at risk of allergic disease
    • Rowntree S, Cogswell JJ, Platts-Mills TA, Mitchell EB. Development of IgE and IgG antibodies to food and inhalant allergens in children at risk of allergic disease. Arch Dis Child 1985;60:727-35.
    • (1985) Arch Dis Child , vol.60 , pp. 727-735
    • Rowntree, S.1    Cogswell, J.J.2    Platts-Mills, T.A.3    Mitchell, E.B.4
  • 15
    • 0027169803 scopus 로고
    • The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production
    • McMenamin C, Holt PG. The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production. J Exp Med 1993;178:889-99.
    • (1993) J Exp Med , vol.178 , pp. 889-899
    • McMenamin, C.1    Holt, P.G.2
  • 16
    • 0027953086 scopus 로고
    • Inhibition of IgE production and normalization of airways responsiveness by sensitized CDS T cells in a mouse model of allergen-induced sensitization
    • Renz H, Lack G, Saloga J, Schwinzer R, Bradley K, Loader J, et al. Inhibition of IgE production and normalization of airways responsiveness by sensitized CDS T cells in a mouse model of allergen-induced sensitization. J Immunol 1994;152:351-60.
    • (1994) J Immunol , vol.152 , pp. 351-360
    • Renz, H.1    Lack, G.2    Saloga, J.3    Schwinzer, R.4    Bradley, K.5    Loader, J.6
  • 17
    • 0029664297 scopus 로고    scopus 로고
    • Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization
    • Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman M, et al. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc Natl Acad Sci U S A 1996;93:5141-5.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5141-5145
    • Raz, E.1    Tighe, H.2    Sato, Y.3    Corr, M.4    Dudler, J.A.5    Roman, M.6
  • 18
    • 0029925502 scopus 로고    scopus 로고
    • Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization
    • Hsu CH, Chua KY, Tao MH, Lai YL, Wu HD, Huang SK, et al. Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization. Nat Med 1996;2:540-4.
    • (1996) Nat Med , vol.2 , pp. 540-544
    • Hsu, C.H.1    Chua, K.Y.2    Tao, M.H.3    Lai, Y.L.4    Wu, H.D.5    Huang, S.K.6
  • 21
    • 0029028998 scopus 로고
    • Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin)
    • Ebner C, Hirschwehr R, Bauer L, Breiteneder H, Valenta R, Ebner H, et al. Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin). J Allergy Clin Immunol 1995;95:962-9.
    • (1995) J Allergy Clin Immunol , vol.95 , pp. 962-969
    • Ebner, C.1    Hirschwehr, R.2    Bauer, L.3    Breiteneder, H.4    Valenta, R.5    Ebner, H.6
  • 22
    • 13344287034 scopus 로고    scopus 로고
    • Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1: Potential use of hypoallergenic isoforms for immunotherapy
    • Ferreira F, Hirtenlehner K, Jilek A, Godnik-Cvar J, Breiteneder H, Grimm R, et al. Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1: potential use of hypoallergenic isoforms for immunotherapy. J Exp Med 1996;183:599-609.
    • (1996) J Exp Med , vol.183 , pp. 599-609
    • Ferreira, F.1    Hirtenlehner, K.2    Jilek, A.3    Godnik-Cvar, J.4    Breiteneder, H.5    Grimm, R.6
  • 23
    • 0025979907 scopus 로고
    • Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs
    • Varney VA, Gaga M, Frew AJ, Aber VR, Kay AB, Durham SR. Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs. Br Med J 1991;302:265-9.
    • (1991) Br Med J , vol.302 , pp. 265-269
    • Varney, V.A.1    Gaga, M.2    Frew, A.J.3    Aber, V.R.4    Kay, A.B.5    Durham, S.R.6
  • 24
    • 0025739170 scopus 로고
    • Differences in clinical and immunologic reactivity of patients allergic to grass pollens and to multiple-pollen species. II. Efficacy of a double-blind, placebo-controlled, specific immunotherapy with standardized extracts
    • Bousquet J, Becker WM, Hejjaoui A, Chanal I, Lebel B, Dhivert H, et al. Differences in clinical and immunologic reactivity of patients allergic to grass pollens and to multiple-pollen species. II. Efficacy of a double-blind, placebo-controlled, specific immunotherapy with standardized extracts. J Allergy Clin Immunol 1991;88:43-53.
    • (1991) J Allergy Clin Immunol , vol.88 , pp. 43-53
    • Bousquet, J.1    Becker, W.M.2    Hejjaoui, A.3    Chanal, I.4    Lebel, B.5    Dhivert, H.6
  • 25
    • 0027443372 scopus 로고
    • Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals
    • Secrist H, Chelen CJ, Wen Y, Marshall JD, Umetsu DT. Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals. J Exp Med 1993;178:2123-30.
    • (1993) J Exp Med , vol.178 , pp. 2123-2130
    • Secrist, H.1    Chelen, C.J.2    Wen, Y.3    Marshall, J.D.4    Umetsu, D.T.5
  • 26
    • 0028901793 scopus 로고
    • Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures
    • Jutel M, Pichler WJ, Skrbic D, Urwyler A, Dahinden C, Muller UR. Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures. J Immunol 1995;154:4187-94.
    • (1995) J Immunol , vol.154 , pp. 4187-4194
    • Jutel, M.1    Pichler, W.J.2    Skrbic, D.3    Urwyler, A.4    Dahinden, C.5    Muller, U.R.6
  • 27
    • 0030003889 scopus 로고    scopus 로고
    • Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma
    • Durham SR, Ying S, Varney VA, Jacobson MR, Sudderick RM, Mackay IS, et al. Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma. J Allergy Clin Immunol 1996;97:1356-65.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 1356-1365
    • Durham, S.R.1    Ying, S.2    Varney, V.A.3    Jacobson, M.R.4    Sudderick, R.M.5    Mackay, I.S.6
  • 28
    • 9844266243 scopus 로고    scopus 로고
    • Immunological changes during specific immunotherapy of grass pollen allergy: Reduced lymphoproliferative responses to grass pollen and shift from Th2 to Th1 in T cell clones specific for Phl p 1, a major grass pollen allergen
    • Ebner C, Siemann U, Bohle B, Willheim M, Wiedermann U, Schenk S, et al. Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to grass pollen and shift from Th2 to Th1 in T cell clones specific for Phl p 1, a major grass pollen allergen. Clin Exp Allergy 1997;27:1007-15.
    • (1997) Clin Exp Allergy , vol.27 , pp. 1007-1015
    • Ebner, C.1    Siemann, U.2    Bohle, B.3    Willheim, M.4    Wiedermann, U.5    Schenk, S.6
  • 29
    • 6844266292 scopus 로고    scopus 로고
    • Bet v l, the major birch pollen allergen, conjugated to crystalline bacterial cell surface proteins, expands allergen-specific T cells of the Th1/Th0 phenotype in vitro by induction of IL-12
    • Jahn-Schmid B, Siemann U, Zenker A, Bohle B, Messner P, Unger FM, et al. Bet v l, the major birch pollen allergen, conjugated to crystalline bacterial cell surface proteins, expands allergen-specific T cells of the Th1/Th0 phenotype in vitro by induction of IL-12. Int Immunol 1997;9:1867-74.
    • (1997) Int Immunol , vol.9 , pp. 1867-1874
    • Jahn-Schmid, B.1    Siemann, U.2    Zenker, A.3    Bohle, B.4    Messner, P.5    Unger, F.M.6
  • 30
    • 0031569601 scopus 로고    scopus 로고
    • Contribution of CpG motifs to the immunogenicity of DNA vaccines
    • Klinman DM, Yamshchikov G, Ishigatsubo Y. Contribution of CpG motifs to the immunogenicity of DNA vaccines. J Immunol 1997; 158:3635-9.
    • (1997) J Immunol , vol.158 , pp. 3635-3639
    • Klinman, D.M.1    Yamshchikov, G.2    Ishigatsubo, Y.3
  • 31
    • 0028097823 scopus 로고
    • Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes
    • Boes B, Hengel H, Ruppert T, Multhaupt G, Koszinowski UH, Kloetzel PM. Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes. J Exp Med 1994;179:901-9.
    • (1994) J Exp Med , vol.179 , pp. 901-909
    • Boes, B.1    Hengel, H.2    Ruppert, T.3    Multhaupt, G.4    Koszinowski, U.H.5    Kloetzel, P.M.6
  • 32
    • 0027214605 scopus 로고
    • Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes
    • Gacynska M, Rock KL, Goldberg AL. Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. Nature 1993;365:264-7.
    • (1993) Nature , vol.365 , pp. 264-267
    • Gacynska, M.1    Rock, K.L.2    Goldberg, A.L.3
  • 33
    • 0029813303 scopus 로고    scopus 로고
    • Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery
    • Pertmer TM, Roberts TR, Haynes JR. Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery. J Virol 1996;70:6119-25.
    • (1996) J Virol , vol.70 , pp. 6119-6125
    • Pertmer, T.M.1    Roberts, T.R.2    Haynes, J.R.3
  • 34
    • 0031929609 scopus 로고    scopus 로고
    • Effects of adjuvants on the immune response to allergens in a murine model of allergen inhalation: Cholera toxin induces a Th1-like response to Bet v l, the major birch pollen allergen
    • Wiedermann U, Jahn-Schmid B, Fritsch R, Bauer L, Renz H, Kraft D, et al. Effects of adjuvants on the immune response to allergens in a murine model of allergen inhalation: cholera toxin induces a Th1-like response to Bet v l, the major birch pollen allergen. Clin Exp Immunol 1998;111:144-51.
    • (1998) Clin Exp Immunol , vol.111 , pp. 144-151
    • Wiedermann, U.1    Jahn-Schmid, B.2    Fritsch, R.3    Bauer, L.4    Renz, H.5    Kraft, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.