Retina-specific gene expression and improved DNA transfection in WERI-Rb1 retinoblastoma cells

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1628, Issue 3, 2003, Pages 169-176

  Reinisalo, Mika ^a   Urtti, Arto ^a   Honkakoski, Paavo ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

DNA transfection; Gene promoter; Interphotoreceptor retinoid binding protein; Phosphodiesterase ; Polyethyleneimine 25; WERI Rb1

Indexed keywords

INTERPHOTORECEPTOR RETINOID BINDING PROTEIN; MESSENGER RNA; PHOSPHODIESTERASE;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA TRANSFECTION; GENE ACTIVITY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; RETINA; RETINOBLASTOMA;

EID: 0043157854     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4781(03)00140-4     Document Type: Article

References (36)

1. Hauswirth W.W., Beaufrere L. Ocular gene therapy: quo vadis? Invest. Ophthalmol. Vis. Sci. 41:2000;2821-2826.
2. Farrar G.J., Kenna P.F., Humphries P. On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention. EMBO J. 21:2002;857-864.
3. Verma I., Somia N. Gene therapy - promises, problems and prospects. Nature. 389:1997;239-242.
4. Morris T.A., Fong W.-B., Ward M.J., Hu H., Fong S.-L. Localization of upstream silencer elements involved in the expression of cone transducin α-subunit (GNAT2). Invest. Ophthalmol. Vis. Sci. 38:1997;196-206.
5. White J.B., Taylor R.E., Pittler S.J. Reproducible high efficiency gene transfer into Y79 retinoblastoma cells using adenofection. J. Neurosci. Methods. 106:2001;1-7.
6. Nie Z., Chen S., Kumar R., Zack D.J. RER, an evolutionarily conserved sequence upstream of the rhodopsin gene, has enhancer activity. J. Biol. Chem. 271:1996;2667-2675.
7. Ying S., Fong S.-L., Fong W.-B., Kao C.-W., Converse R.L., Kao W.-W. A CAT reporter construct containing 277-bp GNAT2 promoter and 214-bp IRBP enhancer is specifically expressed by cone photoreceptor cells in transgenic mice. Curr. Eye Res. 17:1998;777-782.
8. Ogueta S.B., Di Polo A., Flannery J.G., Yamashita C.K., Farber D.B. The human cGMP-PDE β-subunit promoter region directs expression of the gene to mouse photoreceptors. Invest. Ophthalmol. Vis. Sci. 41:2000;4059-4063.
9. Campbell M., Chader G.J. Retinoblastoma cells in tissue culture. Ophthalmic Paediatr. Genet. 9:1988;171-199.
10. Dunn K.C., Aotaki-Keen A.E., Putkey F.R., Hjelmeland L.M. ARPE19, a human retinal pigment epithelial cell line with differentiated properties. Exp. Eye Res. 62:1996;155-169.
11. Davis A., Bernstein P., Bok D., Turner J., Nachtigal M., Hunt R. A human retinal pigment epithelial cell line that retains epithelial characteristics after prolonged culture. Invest. Ophthalmol. Vis. Sci. 36:1995;955-964.
12. Honkakoski P., Moore R., Washburn K., Negishi M. Activation by diverse xenochemicals of the 51-bp phenobarbital-responsive enhancer module in the Cyp2b10 gene. Mol. Pharmacol. 53:1998;597-601.
13. Boussif O., Lezoualc'h F., Zanta M., Megny M., Scherman D., Demeneix B., Behr J.-P. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl. Acad. Sci. U. S. A. 92:1995;7297-7301.
14. Leventis R., Silvius J.R. Interactions of mammalian cells with lipid dispersions containing novel metabolizable cationic amphiphiles. Biochim. Biophys. Acta. 1023:1990;124-132.
15. Chen C., Okayama H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7:1987;2745-2752.
16. Ruponen M., Ylä-Herttuala S., Urtti A. Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfections studies. Biochim. Biophys. Acta. 1415:1999;331-341.
17. Honkakoski P., Jääskeläinen I., Kortelahti M., Urtti A. A novel drug-regulated gene expression system based on the nuclear receptor CAR. Pharm. Res. 18:2001;146-150.
18. Jääskelainen I., Peltola S., Honkakoski P., Mönkkönen J., Urtti A. A lipid carrier with a membrane active component and a small complex size are required for efficient cellular delivery of anti-sense phosphorothioate oligonucleotides. Eur. J. Pharm. Sci. 10:2000;187-193.
19. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods. 65:1983;237-246.
20. McFall R.C., Sery T.W., Makadon M. Characterization of a new continuous cell line derived from a human retinoblastoma. Cancer Res. 37:1977;1003-1010.
21. Di Polo A., Farber D.B. Rod photoreceptor-specific gene expression in human retinoblastoma cells. Proc. Natl. Acad. Sci. U. S. A. 92:1995;4016-4020.
22. Di Polo A., Lerner L.E., Farber D.B. Transcriptional activation of the human rod cGMP-phosphodiesterase β-subunit gene is mediated by an upstream AP-1 element. Nucleic Acids Res. 25:1997;3863-3867.
23. Lerner L.E., Gribanova Y.E., Ji M., Knox B.E., Farber D.B. Nrl and Sp nuclear proteins mediate transcription of rod-specific cGMP-phosphodiesterase β-subunit gene. J. Biol. Chem. 276:2001;34999-35007.
24. Fong S.-L., Morris T.A., Lee C.-H., Donoso L.A., Fong W.-B. Transfection of retinoblastoma cells: localization of cis-acting elements for human interstitial retinoid-binding protein gene. Methods Neurosci. 15:1993;322-330.
25. Fong S.-L., Fong W.-B. Elements regulating the transcription of human interstitial retinoid-binding protein (IRBP) gene in cultured retinoblastoma cells. Curr. Eye Res. 18:1997;283-291.
26. Horbinski C., Stachowiak M.K., Higgins D., Finnegan S.G. Polyethyleneiminemediated transfection of culture postmitotic neurons from rat sympathetic ganglia and adult human retina. BMC Neurosci. 2:2001;2.
27. Abul-Hassan K., Walmsley R., Boulton M. Optimization of nonviral gene transfer to human primary retinal pigment epithelial cells. Curr. Eye Res. 20:2000;361-366.
28. Li A., Zhu X., Craft C.M. Retinoic acid upregulates cone arrestin expression in retinoblastoma cells through a cis-element in the distal promoter region. Invest. Ophthalmol. Vis. Sci. 43:2002;1375-1383.
29. Boatright J.H., Stodulkova E., Do V.T., Padove S.A., Nguyen H.T., Borst D.E., Nickerson J.M. The effect of retinoids and butyrate on the expression of CRX and IRBP in retinoblastoma cells. Vis. Res. 42:2002;933-938.
30. Martinez J.A., Barnstable C.J. Erx, a novel retina-specific homeodomain transcription factor, can interact with Ret 1/PCEI sites. Biochem. Biophys. Res. Commun. 250:1998;175-180.
31. Bernard M., Klein D.C. Retinoic acid increases hydroxyindole-O-methyl-transferase activity and mRNA in human Y-79 retinoblastoma cells. J. Neurochem. 67:1996;1032-1038.
32. Morris T.A., Fong S.-L. Characterization of the gene encoding human cone transducin alpha-subunit (GNAT2). Genomics. 17:1993;442-448.
33. Chelly J., Concordet J.-P., Kaplan J.-C., Kahn A. Illegitimate transcription: transcription of any gene in any cell type. Proc. Natl. Acad. Sci. U. S. A. 86:1989;2617-2621.
34. Webb P., Lopez G.N., Greene G.L., Baxter J.D., Kushner P.J. The limits of the cellular capacity to mediate an estrogen response. Mol. Endocrinol. 6:1992;157-167.
35. Natesan S., Rivera V.M., Molinari E., Gilman M. Transcriptional squelching re-examined. Nature. 390:1997;349-350.
36. Boatright J.H., Borst D.E., Stodulkova E., Nickerson J.M. Endogenous CRX expression and IRBP promoter activity in retinoblastoma cells. Brain Res. 916:2001;136-142.