Design and Characterization of a Hybrid Miniprotein That Specifically Inhibits Porcine Pancreatic Elastase

Journal of Biological Chemistry

Volumn 278, Issue 27, 2003, Pages 24986-24993

  Hilpert, Kai ^a   Wessner, Helga ^a   Schneider Mergener, Jens ^a   Welfle, Karin ^b   Misselwitz, Rolf ^b   Welfle, Heinz ^b   Hocke, Andreas C ^a   Hippenstiel, Stefan ^a   Höhne, Wolfgang ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DEGRADATION; ENTHALPY; ENTROPY; ENZYME IMMOBILIZATION; SPECIFIC HEAT;

ISOTHERMAL TITRATION CALORIMETRY;

PROTEINS;

ECBALLIUM ELATERIUM EXTRACT; HYBRID PROTEIN; OVOMUCOID; PANCREATIC ELASTASE; PROTEINASE; ENZYME INHIBITOR; PEPTIDE FRAGMENT;

ARTICLE; BACTERIAL VIRULENCE; ENDOTHELIUM CELL; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME STABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR RECOGNITION; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN STABILITY; RECEPTOR AFFINITY; SWINE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; GENETICS; MOLECULAR GENETICS; VASCULAR ENDOTHELIUM;

BACTERIA (MICROORGANISMS); ECBALLIUM ELATERIUM; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; SUIDAE; SUS SCROFA;

AMINO ACID SEQUENCE; ANIMALS; DRUG DESIGN; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; MOLECULAR SEQUENCE DATA; PANCREATIC ELASTASE; PEPTIDE FRAGMENTS; RECOMBINANT FUSION PROTEINS; SWINE;

EID: 0043092182     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212152200     Document Type: Article

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