Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures

Journal of Neurochemistry

Volumn 86, Issue 4, 2003, Pages 792-804

  Rego, Ana Cristina ^a   Monteiro, Nuno M ^a   Silva, Ana P ^a   Gil, Joana ^a   Malva, João O ^a   Oliveira, Catarina R ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

AMPA receptors; Caspases; Cytochrome c; Hippocampal neurones; Neurotoxicity; Reactive oxygen species

Indexed keywords

6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; ANTIMYCIN A1; CALCIUM; CALCIUM PERMEABLE AMPA RECEPTOR; CASPASE 3; CYCLOTHIAZIDE; CYTOCHROME C; DIZOCILPINE; INTERLEUKIN 1BETA CONVERTING ENZYME; MANGANESE SUPEROXIDE DISMUTASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NON DESENSITIZING AMPA RECEPTOR; PEROXIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME RELEASE; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; MITOCHONDRION; NERVE CELL CULTURE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; RECEPTOR DOWN REGULATION INHIBITION; RECEPTOR UPREGULATION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; APOPTOSIS; CASPASES; CELLS, CULTURED; CYTOCHROME C GROUP; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; HIPPOCAMPUS; MITOCHONDRIA; N-METHYLASPARTATE; NECROSIS; NEURONS; RATS; RATS, WISTAR; RECEPTORS, AMPA; SUPEROXIDE DISMUTASE; SUPEROXIDES;

ANIMALIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0043068059     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01898.x     Document Type: Article

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