A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene

Drug Metabolism and Disposition

Volumn 31, Issue 8, 2003, Pages 1054-1064

  Zhang, Weisheng ^a   Purchio, Anthony F ^a   Chen, Kevin ^a   Wu, Jianming ^a   Lu, Li ^a   Coffee, Richard ^b   Contag, Pamela R ^a   West, David B ^a  

^a Xenogen Corporation   (United States)

^b Xenogen Biosciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA CYANOPREGNENOLONE; CLOTRIMAZOLE; CYTOCHROME P450 3A4; DEXAMETHASONE; DIMETHYL SULFOXIDE; LUCIFERASE; NIFEDIPINE; PHENOBARBITAL; PREGNENOLONE; RIFAMPICIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG EFFECT; DUODENUM; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; IMAGING SYSTEM; IN VIVO STUDY; KIDNEY; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE;

ANIMALS; CLOTRIMAZOLE; CYTOCHROME P-450 ENZYME SYSTEM; DEXAMETHASONE; DIMETHYL SULFOXIDE; DUODENUM; ENZYME INDUCTION; FEMALE; FIREFLY LUCIFERIN; GENES, REPORTER; HUMANS; INJECTIONS, INTRAPERITONEAL; KIDNEY; LIVER; LUCIFERASES; LUMINESCENT MEASUREMENTS; MALE; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; PREGNENOLONE CARBONITRILE; SEX FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA; MUS MUSCULUS;

EID: 0043027091     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.31.8.1054     Document Type: Article

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