Lack of gender differences and large intrasubject variability in cytochrome P450 activity measured by phenotyping with dextromethorphan

Journal of Clinical Pharmacology

Volumn 41, Issue 7, 2001, Pages 723-731

  McCune, J S ^a   Lindley, C ^a   Decker, J L ^a   Williamson, K M ^a   Meadowcroft, A M ^a   Graff, D ^a   Sawyer, W T ^a   Blough, D K ^a   Pieper, J A ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; DEXTROMETHORPHAN; ESTROGEN; ETHINYLESTRADIOL PLUS LEVONORGESTREL; GUAIFENESIN; MORPHINAN DERIVATIVE; PROGESTERONE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DIAGNOSTIC VALUE; DRUG METABOLISM; DRUG URINE LEVEL; ENZYME ACTIVITY; ESTROGEN BLOOD LEVEL; FEMALE; GENDER; HUMAN; MALE; MENSTRUAL CYCLE; ORAL CONTRACEPTION; PHENOTYPE; PROGESTERONE BLOOD LEVEL; SEX DIFFERENCE;

ADULT; ANALYSIS OF VARIANCE; CONTRACEPTIVES, ORAL, COMBINED; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 ENZYME SYSTEM; DEXTROMETHORPHAN; ETHINYL ESTRADIOL-NORGESTREL COMBINATION; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; HUMANS; MALE; MENSTRUATION; MIXED FUNCTION OXYGENASES; PHENOTYPE; PILOT PROJECTS; SEX CHARACTERISTICS;

EID: 0034963104     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/00912700122010627     Document Type: Article

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