pRb inactivation in senescent cells leads to an E2F-dependent apoptosis requiring p73

Molecular Cancer Research

Volumn 1, Issue 10, 2003, Pages 716-728

  Alexander, Kamilah ^a,b   Yang, Hai Su ^a   Hinds, Philip W ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE; CYCLIN E; MUTANT PROTEIN; PROTEIN P73; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F;

APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DEATH; CELL PROLIFERATION; DNA SYNTHESIS INHIBITION; EFFECTOR CELL; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE REPRESSION; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; MITOGENICITY; PHASE TRANSITION; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

APOPTOSIS; BLOTTING, WESTERN; CELL AGING; CELL CYCLE; CELL CYCLE PROTEINS; CYCLIN E; CYCLIN-DEPENDENT KINASES; DNA REPLICATION; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENES, TUMOR SUPPRESSOR; HUMANS; NUCLEAR PROTEINS; RETINOBLASTOMA PROTEIN; S PHASE; TEMPERATURE; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0042929916     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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