Membranolytic selectivity of cystine-stabilized cyclic protegrins

European Journal of Biochemistry

Volumn 267, Issue 11, 2000, Pages 3289-3300

  Tam, James P ^a   Wu, Chengwei ^a   Yang, Jin Long ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Circular dichroism; Cystine knot; Peptide antibiotics; Peptide synthesis; Protegrin

Indexed keywords

CYCLOPEPTIDE; CYSTINE; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEGRIN;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CIRCULAR DICHROISM; CYTOTOXICITY; DISULFIDE BOND; HEMOLYSIS; HUMAN; HUMAN CELL; MEMBRANE DAMAGE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; ANTI-HIV AGENTS; ANTI-INFECTIVE AGENTS; ANTIFUNGAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CANDIDA; CELL MEMBRANE; CIRCULAR DICHROISM; CYSTINE; ERYTHROCYTE MEMBRANE; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HEMOLYSIS; HIV-1; HUMANS; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEINS; SOLUTIONS; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRIFLUOROETHANOL; WATER;

EID: 0034113230     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01359.x     Document Type: Article

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