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Volumn 131, Issue 3, 2003, Pages 189-194

Theophylline suppresses IL-5 and IL-13 production, and lymphocyte proliferation upon stimulation with house dust mite in asthmatic children

Author keywords

Bronchial asthma; House dust mite; IL 13; IL 5; Lymphocyte proliferation; Theophylline

Indexed keywords

HOUSE DUST ALLERGEN; INTERLEUKIN 13; INTERLEUKIN 5; THEOPHYLLINE;

EID: 0042665754     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000071485     Document Type: Article
Times cited : (8)

References (48)
  • 1
    • 0021363780 scopus 로고
    • The pharmacology and therapeutic use of theophylline
    • Weinberger M: The pharmacology and therapeutic use of theophylline. J Allergy Clin Immunol 1984;73:525-541.
    • (1984) J Allergy Clin Immunol , vol.73 , pp. 525-541
    • Weinberger, M.1
  • 2
    • 0001987297 scopus 로고    scopus 로고
    • Allergic disorders
    • Behrman RE, Kliegman RM, Jenson HB (eds). Philadelphia, Saunders
    • Sly RM: Allergic disorders; in Behrman RE, Kliegman RM, Jenson HB (eds): Nelson Textbook of Pediatrics, ed 16. Philadelphia, Saunders, 2000, pp 645-697.
    • (2000) Nelson Textbook of Pediatrics, Ed 16 , pp. 645-697
    • Sly, R.M.1
  • 3
    • 0019058162 scopus 로고
    • Emergency therapy of asthma: Comparison of the acute effects of parenteral and inhaled sympathomimetics and infused aminophylline
    • Rossing TH, Fanta CH, Goldstein DH, Snapper JR, McFadeen ER Jr: Emergency therapy of asthma: Comparison of the acute effects of parenteral and inhaled sympathomimetics and infused aminophylline. Am Rev Respir Dis 1980;122:365-371.
    • (1980) Am Rev Respir Dis , vol.122 , pp. 365-371
    • Rossing, T.H.1    Fanta, C.H.2    Goldstein, D.H.3    Snapper, J.R.4    McFadeen E.R., Jr.5
  • 6
    • 0022992986 scopus 로고
    • Overview of effects of theophylline
    • Persson CGD: Overview of effects of theophylline. J Allergy Clin Immunol 1989;78:780-787.
    • (1989) J Allergy Clin Immunol , vol.78 , pp. 780-787
    • Persson, C.G.D.1
  • 8
    • 0030719429 scopus 로고    scopus 로고
    • A comparison of low-dose inhaled budesonide plus theophylline and high-dose inhaled budesonide for moderate asthma
    • Evans DJ, Taylor DA, Zetterstrom O, Chung KF O'Connor BJ, Barnes PJ: A comparison of low-dose inhaled budesonide plus theophylline and high-dose inhaled budesonide for moderate asthma. N Engl J Med 1997;337:1412-1418.
    • (1997) N Engl J Med , vol.337 , pp. 1412-1418
    • Evans, D.J.1    Taylor, D.A.2    Zetterstrom, O.3    Chung, K.F.4    O'Connor, B.J.5    Barnes, P.J.6
  • 9
    • 0028344025 scopus 로고
    • Anti-inflammatory effects of low-dose oral theophylline in atopic asthma
    • Sullivan P, Bekir S, Jaffar Z, Page C, Jeffery P, Costello J: Anti-inflammatory effects of low-dose oral theophylline in atopic asthma. Lancet 1994;343:1006-1008.
    • (1994) Lancet , vol.343 , pp. 1006-1008
    • Sullivan, P.1    Bekir, S.2    Jaffar, Z.3    Page, C.4    Jeffery, P.5    Costello, J.6
  • 10
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secretory proteins
    • Mosmann TR, Cherwinski H, Bond MW, Giedlin MH, Coffman R: Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secretory proteins. J Immunol 1986;136:2348-2357.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.H.4    Coffman, R.5
  • 12
    • 0034065298 scopus 로고    scopus 로고
    • The role of lymphocytes in allergic disease
    • Romagnani S: The role of lymphocytes in allergic disease. J Allergy Clin Immunol 2000;105:399-408.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 399-408
    • Romagnani, S.1
  • 13
    • 0023875104 scopus 로고
    • Purified interleukin (IL-5) supports the terminal differentiation and proliferation of murine eosinophilic precursors
    • Yamaguchi Y, Suda T, Suda J, Eguchi M, Miura Y, Harada N, Tominaga A, Takatsu K: Purified interleukin (IL-5) supports the terminal differentiation and proliferation of murine eosinophilic precursors. J Exp Med 1988;167:43-56.
    • (1988) J Exp Med , vol.167 , pp. 43-56
    • Yamaguchi, Y.1    Suda, T.2    Suda, J.3    Eguchi, M.4    Miura, Y.5    Harada, N.6    Tominaga, A.7    Takatsu, K.8
  • 14
    • 0024591512 scopus 로고
    • Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: Comparison and interaction with IL-1, IL-3, and GM-CSF
    • Clutterbuck EJ, Hirst EMA, Sanderson CJ: Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: Comparison and interaction with IL-1, IL-3, and GM-CSF. Blood 1989;73:1504-1512.
    • (1989) Blood , vol.73 , pp. 1504-1512
    • Clutterbuck, E.J.1    Hirst, E.M.A.2    Sanderson, C.J.3
  • 16
    • 0027320031 scopus 로고
    • Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma
    • Robinson D, Hamid Q, Bentley A, Ying S, Kay AB, Durham SR: Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma. J Allergy Clin Immunol 1993;92:313-324.
    • (1993) J Allergy Clin Immunol , vol.92 , pp. 313-324
    • Robinson, D.1    Hamid, Q.2    Bentley, A.3    Ying, S.4    Kay, A.B.5    Durham, S.R.6
  • 18
    • 0035141618 scopus 로고    scopus 로고
    • IL-12/IL-13 axis in allergic asthma
    • Willis-Karp M: IL-12/IL-13 axis in allergic asthma. J Allergy Clin Immunol 2001;107:9-18.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 9-18
    • Willis-Karp, M.1
  • 23
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA: Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999;103:779-788.
    • (1999) J Clin Invest , vol.103 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6    Zhang, Y.7    Elias, J.A.8
  • 24
    • 0033104696 scopus 로고    scopus 로고
    • Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells
    • Li L, Xia Y, Nguyen A, Lai YH, Feng L, Mosmann TR, Lo D: Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. J Immunol 1999;162:2477-2487.
    • (1999) J Immunol , vol.162 , pp. 2477-2487
    • Li, L.1    Xia, Y.2    Nguyen, A.3    Lai, Y.H.4    Feng, L.5    Mosmann, T.R.6    Lo, D.7
  • 28
    • 0032747618 scopus 로고    scopus 로고
    • Differences in cytokine production by peripheral blood mononuclear cells (PBMC) between patients with atopic dermatitis and bronchial asthma
    • Kimura M, Tsuruta S, Yoshida T: Differences in cytokine production by peripheral blood mononuclear cells (PBMC) between patients with atopic dermatitis and bronchial asthma. Clin Exp Immunol 1999;118:192-196.
    • (1999) Clin Exp Immunol , vol.118 , pp. 192-196
    • Kimura, M.1    Tsuruta, S.2    Yoshida, T.3
  • 29
    • 0033976726 scopus 로고    scopus 로고
    • IL-4 production by PBMCs on stimulation with mite allergen is correlated with the level of serum IgE antibody against mite in children with bronchial asthma
    • Kimura M, Tsuruta S, Yoshida T: IL-4 production by PBMCs on stimulation with mite allergen is correlated with the level of serum IgE antibody against mite in children with bronchial asthma. J Allergy Clin Immunol 2000;105:327-332.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 327-332
    • Kimura, M.1    Tsuruta, S.2    Yoshida, T.3
  • 30
    • 0019453154 scopus 로고
    • Lymphocyte responsiveness to Dermatophagoides farinae extract in mite sensitive patients: Effect of immunotherapy on cellular proliferative response and specific immunoglobulin E antibody (RAST score)
    • Hiratani M, Muto K, Oshida Y, Ito S, Kasei M: Lymphocyte responsiveness to Dermatophagoides farinae extract in mite sensitive patients: Effect of immunotherapy on cellular proliferative response and specific immunoglobulin E antibody (RAST score). J Allergy Clin Immunol 1981;68:205-211.
    • (1981) J Allergy Clin Immunol , vol.68 , pp. 205-211
    • Hiratani, M.1    Muto, K.2    Oshida, Y.3    Ito, S.4    Kasei, M.5
  • 31
    • 0021191538 scopus 로고
    • T cell responses to the major allergen from the house dust mite Dermatophagoides pteronyssinus, Antigen P1: Comparison of patients with asthma, atopic dermatitis, and perennial rhinitis
    • Rawle FC, Mitchell EB, Platts-Mills TAE: T cell responses to the major allergen from the house dust mite Dermatophagoides pteronyssinus, Antigen P1: Comparison of patients with asthma, atopic dermatitis, and perennial rhinitis. J Immunol 1984;133:195-201.
    • (1984) J Immunol , vol.133 , pp. 195-201
    • Rawle, F.C.1    Mitchell, E.B.2    Platts-Mills, T.A.E.3
  • 32
    • 0032571017 scopus 로고    scopus 로고
    • The structure and function of A1 and A2B adenosine receptors
    • Linden J, Auchampach JA, Jin X, Figler RA: The structure and function of A1 and A2B adenosine receptors. Life Sci 1998;62:1519-1524.
    • (1998) Life Sci , vol.62 , pp. 1519-1524
    • Linden, J.1    Auchampach, J.A.2    Jin, X.3    Figler, R.A.4
  • 33
    • 0025727421 scopus 로고
    • Regulation of Ig-induced eosinophil degranulation by adenosine 3′,5′-cyclic monophosphate
    • Kita H, Abu-Ghazaleh RI, Gleich GJ, Abraham RT: Regulation of Ig-induced eosinophil degranulation by adenosine 3′,5′-cyclic monophosphate. J Immunol 1991;146:2712-2718.
    • (1991) J Immunol , vol.146 , pp. 2712-2718
    • Kita, H.1    Abu-Ghazaleh, R.I.2    Gleich, G.J.3    Abraham, R.T.4
  • 39
    • 0034253389 scopus 로고    scopus 로고
    • The downregulation of Bcl-2 expression is necessary for theophylline-induced apoptosis of eosinophils
    • Chung IY, Nam-Kung EK, Lee NM, Chang HS, Kim DJ, Kim YH, Park CS: The downregulation of Bcl-2 expression is necessary for theophylline-induced apoptosis of eosinophils. Cell Immunol 2000;203:95-102.
    • (2000) Cell Immunol , vol.203 , pp. 95-102
    • Chung, I.Y.1    Nam-Kung, E.K.2    Lee, N.M.3    Chang, H.S.4    Kim, D.J.5    Kim, Y.H.6    Park, C.S.7
  • 40
    • 0029793188 scopus 로고    scopus 로고
    • Theophylline's effect on neutrophil function and the late asthmatic response
    • Kraft M, Pak J, Borish L, Martin RJ: Theophylline's effect on neutrophil function and the late asthmatic response. J Allergy Clin Immunol 1996;98:251-257.
    • (1996) J Allergy Clin Immunol , vol.98 , pp. 251-257
    • Kraft, M.1    Pak, J.2    Borish, L.3    Martin, R.J.4
  • 41
    • 0030984157 scopus 로고    scopus 로고
    • Theophylline accelerates human granulocyte apotosis not via phosphodiesterase inhibition
    • Yasui K, Hu B, Nakazawa T, Agematsu K, Komiyama A: Theophylline accelerates human granulocyte apotosis not via phosphodiesterase inhibition. J Clin Invest 1997;100:1677-1684.
    • (1997) J Clin Invest , vol.100 , pp. 1677-1684
    • Yasui, K.1    Hu, B.2    Nakazawa, T.3    Agematsu, K.4    Komiyama, A.5
  • 43
    • 0021269565 scopus 로고
    • The effect of theophyllamine on T-lymphocyte activation in vitro
    • Bruserud Ø: The effect of theophyllamine on T-lymphocyte activation in vitro. Clin Immunol Immunopathol 1984;32:111-118.
    • (1984) Clin Immunol Immunopathol , vol.32 , pp. 111-118
    • Bruserud, Ø.1
  • 44
    • 0029881921 scopus 로고    scopus 로고
    • Phosphodiesterase inhibitors suppress proliferation of peripheral blood mononuclear cells and interleukin-4 and -5 secretion by human T-helper type 2 cells
    • Crocker IC, Townley RG, Khan MM: Phosphodiesterase inhibitors suppress proliferation of peripheral blood mononuclear cells and interleukin-4 and -5 secretion by human T-helper type 2 cells. Immunopharmacology 1996;31:223-235.
    • (1996) Immunopharmacology , vol.31 , pp. 223-235
    • Crocker, I.C.1    Townley, R.G.2    Khan, M.M.3
  • 45
    • 0032008161 scopus 로고    scopus 로고
    • Modulation of Th1- and Th2-like cytokine production from mitogen-stimulated human peripheral blood mononuclar cells by phosphodiesterase inhibitors
    • Yoshimura T, Nagao T, Nakao T, Watanabe S, Usami E, Kabayashi J, Yamazaki F, Tanaka H, Inagaki N, Nagai H: Modulation of Th1- and Th2-like cytokine production from mitogen-stimulated human peripheral blood mononuclar cells by phosphodiesterase inhibitors. Gen Pharmacol 1998;30:175-180.
    • (1998) Gen Pharmacol , vol.30 , pp. 175-180
    • Yoshimura, T.1    Nagao, T.2    Nakao, T.3    Watanabe, S.4    Usami, E.5    Kabayashi, J.6    Yamazaki, F.7    Tanaka, H.8    Inagaki, N.9    Nagai, H.10
  • 46
    • 0032720872 scopus 로고    scopus 로고
    • Effects of theophylline, dexamethasone and salbutamol on cytokine gene expression in human peripheral blood CD4+ T-cells
    • Choy DKL, Ko F, Li ST, Ip LS, Leung R, Hui D, Lai KN, Lai CKW: Effects of theophylline, dexamethasone and salbutamol on cytokine gene expression in human peripheral blood CD4+ T-cells. Eur Respir J 1999;14:1106-1112.
    • (1999) Eur Respir J , vol.14 , pp. 1106-1112
    • Choy, D.K.L.1    Ko, F.2    Li, S.T.3    Ip, L.S.4    Leung, R.5    Hui, D.6    Lai, K.N.7    Lai, C.K.W.8
  • 48
    • 0031890102 scopus 로고    scopus 로고
    • Correlation of house dust mite-specific lymphocyte proliferation with interleukin 5 production, eosinophilia, and the severity of symptoms in infants with atopic dermatitis
    • Kimura M, Tsuruta S, Yoshida T: Correlation of house dust mite-specific lymphocyte proliferation with interleukin 5 production, eosinophilia, and the severity of symptoms in infants with atopic dermatitis. J Allergy Clin Immunol 1998;101:84-89.
    • (1998) J Allergy Clin Immunol , vol.101 , pp. 84-89
    • Kimura, M.1    Tsuruta, S.2    Yoshida, T.3


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